Diego Boscá

Polytechnic University of Valencia | UPV · Institute for Information and Communication Technologies (ITACA)

This work presents methods to combine data from the Semantic Web into existing EHRs, leading to an augmented EHR. An existing EHR extract is augmented by combining it with additional information from external sources, typically linked data sources. The starting point is a standardized EHR extract described by an archetype. The method consists of co...

Background SNOMED CT Expression Constraint Language (ECL) is a declarative language developed by SNOMED International for the definition of SNOMED CT Expression Constraints (ECs). ECs are executable expressions that define intensional subsets of clinical meanings by stating constraints over the logic definition of concepts. The execution of an EC o...

Currently, data management in oncology department is complex and requires advanced Information Systems (ISs) to process data where "omic" information should be integrated together with patient's clinical data to improve data analysis and decision-making process. This research paper reports a practical experience in this context. A Conceptual Model...

At present, research activities and clinical practice make typically use of two completely separate classes of models, methodologies and tools to support data management. From the research side, for example, the OMOP vocabulary and the MIABIS standard are used to characterise samples within the biobank context and beyond. In clinical practice, open...

Somatic mutation analysis and evaluation of microsatellite instability (MSI) have become mandatory for selecting personalized therapy strategies for advanced colorectal cancer and are not available as routine methods in Paraguay. The aims of this study were to analyze the molecular profile as well as the microsatellite status in a series of advance...

The heterogeneity of clinical data is a key problem in the sharing and reuse of Electronic Health Record (EHR) data. We approach this problem through the combined use of EHR standards and semantic web technologies, concretely by means of clinical data transformation applications that convert EHR data in proprietary format, first into clinical infor...

We present the results of a pilot project of the Spanish Ministry of Health, Social Services and Equality, envisaged to the development of a national integrated data repository of maternal-child care information. Based on health information standards and data quality assessment procedures, the developed repository is aimed to a reliable data reuse...

The heterogeneity of clinical data is a key problem in the sharing and reuse of Electronic Health Record (EHR) data. We approach this problem through the combined use of EHR standards and semantic web technologies, concretely by means of clinical data transformation applications that convert EHR data in proprietary format, first into clinical infor...

The need to achieve high levels of semantic interoperability in the health domain is regarded as a crucial issue. Nowadays, one of the weaknesses when working in this direction is the lack of a coordinated use of information and terminological models to define the meaning and content of clinical data. IHTSDO is aware of this problem and has recentl...

The need to achieve high levels of semantic interoperability in the health domain is regarded as a crucial issue. Nowadays, one of the weaknesses when working in this direction is the lack of a coordinated use of information and terminological models to define the meaning and content of clinical data. IHTSDO is aware of this problem and has recentl...

Messaging standards, and specifically HL7 v2, are heavily used for the communication and interoperability of Health Information Systems. HL7 FHIR was created as an evolution of the messaging standards to achieve semantic interoperability. FHIR is somehow similar to other approaches like the dual model methodology as both are based on the precise mo...

Clinical information models are increasingly used to describe the contents of Electronic Health Records. Implementation guides are a common specification mechanism used to define such models. They contain, among other reference materials, all the constraints and rules that clinical information must obey. However, these implementation guides typical...

This paper describes the design and implementation of a clinical-oriented tool for the definition of HL7 CDA templates based on the archetype methodology proposed by CEN/ISO 13606 and openEHR. The use of archetypes together with HL7 CDA brings along new possibilities for clinical model definitions based on CDA. It allows taking profit of the formal...

In this work we present the Concept Oriented Repository (ROC), a system developed for the management of clinical information models, also known as detailed clinical models (DCM). It has been developed to be used in the Electronic Health Record project of the Valencia regional health agency (AVS). The system uses DCMs as a way to define clinical mod...

Communicating genetic testing reports of a patient in a semantically interoperable way remains difficult. Most of the information is stored as non-communicable documents which cannot automatically be processed. The objective of the project was to obtain semantically interoperable genetic testing reports which could be used not only for communicatio...

The generation of a semantic clinical infostructure requires linking ontologies, clinical models and terminologies [1]. Here we describe an approach that would permit data coming from different sources and represented in different standards to be queried in a homogeneous and integrated way. Our assumption is that data providers should be able to ag...

Clinical decision-support systems (CDSSs) comprise systems as diverse as sophisticated platforms to store and manage clinical data, tools to alert clinicians of problematic situations, or decision-making tools to assist clinicians. Irrespective of the kind of decision-support task CDSSs should be smoothly integrated within the clinical information...

Normalization of data is a prerequisite to achieve semantic interoperability in any domain. This is even more important in the healthcare sector due to the special sensitivity of medical data: data exchange must be done in a meaningful way, avoiding any possibility of misunderstanding or misinterpretation. In this chapter, we present the LinkEHR sy...

Possibly the most important requirement to support co-operative work among health professionals and institutions is the ability of sharing EHRs in a meaningful way, and it is widely acknowledged that standardization of data and concepts is a prerequisite to achieve semantic interoperability in any domain. Different international organizations are w...

Clinical guidelines contain recommendations based on the best empirical evidence available at the moment. There is a wide consensus about the benefits of guidelines and about the fact that they should be deployed through clinical information systems, making them available during consultation time. However, one of the main obstacles to this integrat...

In this paper, we present the ResearchEHR project. It focuses on the usability of Electronic Health Record (EHR) sources and EHR standards for building advanced clinical systems. The aim is to support healthcare professional, institutions and authorities by providing a set of generic methods and tools for the capture, standardization, integration,...

Since the approval of the CEN EN13606 norm for the electronic health record communication, a growing interest around the application of this specification has emerged. The main objective of the norm is to serve as a mechanism to achieve the semantic interoperability of clinical data. This will require an effort to use common terminologies, to norma...

To develop a powerful archetype editing framework capable of handling multiple reference models and oriented towards the semantic description and standardization of legacy data. The main prerequisite for implementing tools providing enhanced support for archetypes is the clear specification of archetype semantics. We propose a formalization of the...

The construction of a Virtual Federated Electronic Health Record (VFEHR) requires using standards, tools and an adequate technological infrastructure. We have developed LinkEHR as a framework platform for the standardization, integration and sharing of health information among distributed and heterogeneous Health Information Systems. To perform thi...

We present the mapping and data transformation capabilities of LinkEHR-Ed, a visual tool to construct formal definitions of medical concepts in the form of archetypes which can be defined on the basis on multiple electronic health record architecture such as ISO 13606. With LinkEHR-Ed, users can enrich archetypes with mapping information which capt...

The International Organization for Standardization (ISO) has recently approved a new standard for the communication and semantic interoperability of electronic health record extracts. This standard is based on a dual model architecture, where a simple and generic reference model is defined for the representation of data and an archetype model is us...

Motivation Healthcare is a very data-intensive sector, producing and consuming a great amount of biomedical information. In healthcare organizations, especially hospitals, the big amount of data gets increasingly obscure due to their decentralized organization which has allowed different departments to meet specific or local requirements. This has...

One of the basic needs for any healthcare professional is to be able to access to clinical information of patients in an understandable and normalized way. The lifelong clinical information of any person supported by electronic means configures his/her Electronic Health Record (EHR). This information is usually distributed among several independent...

Resumen Una de las necesidades básicas de cualquier profesional sanitario es tener acceso al registro de todos los datos clínicos disponibles de sus pacientes. Cuando esta información está en soporte informático (Historia Clínica Electrónica o HCE) normalmente está distribuida por diversos sistemas autónomos y heterogéneos cuya interopeabilidad es...

During last years great efforts have been made on Healthcare systems computerization. Those efforts are a great leap on both quantitative and qualitative patient care. However, nearly all of current developed systems are still being built ad-hoc for each organization. This makes the communication between organizations a time and money consuming tas...

The demographic information management of the patients in an information system is usually considered a secondary problem. This causes that the demographic information is scattered around the organization or stored along with the clinical information. With the standardization of the clinical information becoming a popular topic, the standardization...

Privacy of personal health information is the target of many efforts of Health Information Systems administrators. But every person has the right to gain access and control his own information security rules. In this work we propose a framework for the definition of access policies oriented to its use by the legal owners of data: the patients. At t...