Didier Zugaj

Didier Zugaj
Ajou University · Department of Dermatology

Doctor of Philosophy

About

20
Publications
1,865
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398
Citations

Publications

Publications (20)
Article
Background Rosacea is a chronic inflammatory skin disease. Characteristic vascular changes in rosacea skin include enlarged, dilated vessels of the upper dermis and blood flow increase. Brimonidine is approved for symptomatic relief of the erythema of rosacea. It acts by selectively binding to α2‐adrenergic receptors present on smooth muscle in the...
Article
Skin is one of the most important organs of the human body because of its characteristics and functions. There are many alterations, either pathological or physiological, that can disturb its functioning. However, at present all methods used to investigate skin diseases, non‐invasive or invasive, are based on clinical examinations by physicians. Th...
Article
Background: One major sequelae of acne is atrophic scarring, yet objective tools to assess scars are lacking. Neither depth nor volume of atrophic scars is readily evaluable clinically and standard 2D photography is significantly affected by lighting and shadows. The aim of our study was to define and evaluate parameters of 3D imaging that can be...
Article
Full-text available
Background: Currently, imaging technologies that can accurately assess or provide surrogate markers of the human cutaneous microvessel network are limited. Dynamic optical coherence tomography (D-OCT) allows the detection of blood flow in vivo and visualization of the skin microvasculature. However, image processing is necessary to correct images,...
Article
Full-text available
During the evaluation of skin disease treatments, dermatologists have to clinically measure the evolution of the pathology severity of each patient during treatment periods. Such a process is sensitive to intra- and inter- dermatologist diagnosis. To make this severity measurement more objective we quantify the pathology severity using a new image...
Conference Paper
Full-text available
In this paper, we use statistical inference and muti-spectral images to quantify the evolution of skin hyper-pigmentation lesions under treatment. We show that statistical inference allows getting change maps of the disease which can be useful for dermatologists to analyze the disease evolution. Indeed, a local change map is obtained by computing t...
Article
Full-text available
During evaluation of skin disease treatments, dermatologists have to clinically measure the pathology severity of each patient during treatment periods. Such a process is sensitive to intra- and inter- dermatologist diagnosis. To make this severity measurement more robust we propose to use image processing to quantify the pathology severity. We foc...
Article
Full-text available
According to clinical protocols, skin diseases are quantified by dermatologists throughout a treatment period, and then a statistical test on these measures allows to evaluate a treatment efficacy. The first step of this process it to classify pathological interest areas. This task is challenging due to the high variability of the images in one cli...
Conference Paper
Full-text available
Clinical evaluation of skin treatments consists of two steps. First, the degree of the disease is measured clinically on a group of patients by dermatologists. Then, a statistical test is used on obtained set of measures to determine the treatment efficacy. In this paper, a method is proposed to automatically measure the severity of skin hyperpigme...
Article
Melasma is a commonly acquired hyperpigmentary disorder of the face, but its pathogenesis is poorly understood and its treatment remains challenging. We conducted a comparative histological study on lesional and perilesional normal skin to clarify the histological nature of melasma. Significantly, higher amounts of melanin and of melanogenesis-asso...
Conference Paper
Full-text available
In this paper, we compare two different approaches for semiautomatic detection of skin hyper-pigmentation on multi-spectral images. These two methods are support vector machine (SVM) and blind source separation. To apply SVM, a dimension reduction method adapted to data classification is proposed. It allows to improve the quality of SVM classificat...
Conference Paper
Full-text available
Data reduction procedures and classification via support vector machines (SVMs) are often associated with multi or hyperspectral image analysis. In this paper, we propose an automatic method with these two schemes in order to perform a classification of skin hyper-pigmentation on multi-spectral images. We propose a spectral analysis method to parti...
Article
Please cite this paper as: In vivo reflectance confocal microscopy detects pigmentary changes in melasma at a cellular level resolution. Experimental Dermatology 2010; 19: e228–e233. Abstract: Melasma is a frequent pigmentary disorder caused by abnormal melanin deposits in the skin. In vivo reflectance confocal microscopy (RCM) is a repetitive imag...
Conference Paper
Quantum Dots (QDs) are semiconductor crystals with nanometer dimensions, which have fluorescence properties that can be adjusted through controlling their diameter. Under ultraviolet light excitation, these nanocrystals re-emit photons in the visible spectrum, with a wavelength ranging from red to blue as their size diminishes. We created an experi...
Conference Paper
Full-text available
We present a video analysis and indexing engine, that can perform fully automatic scene segmentation and feature extraction, in the context of a television archive, based on a library of image analysis functions and templates.
Article
Image segmentation requires processing of a huge volume of data. It is therefore necessary, for their implementation in industrial computer controlled systems, to search for straightforward algorithms. Presently, literature offers a lot of gray-tone image segmentation techniques, but few of them attend to color image segmentation. This paper presen...
Article
On présente dans cet article deux contours actifs dits paramétriques qui nous servent pour asservir par système de vision, une machine de déroulement d'une bobine de film plastique. On montre leur aptitude à déterminer le rayon de la bobine et à suivre très précisément une boucle de très faible épaisseur qui présente des occlusions partielles. On p...
Article
Nous nous intéressons au partitionnement temporel de vidéo, qui est une étape nécessaire dans l'analyse du contenu d'un document audiovisuel en vue de son indexation et de son exploitation. L'objectif est plus particulièrement la détection de volets qui sont des transitions progressives fréquemment utilisées dans le montage de vidéo et le changemen...

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