Dianne Trussell- BSc Hons
- Alumni member at Flinders University
Dianne Trussell
- BSc Hons
- Alumni member at Flinders University
About
16
Publications
436
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709
Citations
Introduction
Science is my first love. However I'm usually outside the box-ticking exercises! But seriously, Bachelor of Science with Honours (major in Biological Sciences plus Psychology, Earth Sciences and Chemistry), 17 years in university medical and biological research, a list of peer-reviewed papers as part of research teams, experience as Problem-based Learning tutor to Graduate Medical students, presenter at 4 conferences on the science of consciousness in the last 3 years... some boxes ticked!
Skills and Expertise
Current institution
Additional affiliations
January 1990 - December 1992
Position
- Research Assistant
Description
- Immunohistochemical localization of neuropeptides in nerve fibres of human ureter, kidney and bladder. Discovered layer-specific patterns of neuropeptide distribution, analogous to that found in intestines.
January 1998 - December 1998
January 1998 - April 1999
Publications
Publications (16)
The physiological characteristics of central neural populations are being increasingly explored in slice preparations. A major challenge of this approach is to correlate the physiological properties of individual neurones or groups of neurones with their anatomical and chemical properties in order to gain key insights into their functional identiti...
The patterns of colocalisation of neuropeptides, tyrosine hydroxylase (TH), and protein gene product 9.5 (PGP), were studied in nerve fibres supplying the upper and lower human ureter using a double labelling immunofluorescence technique. The majority (85%-95%) of nerve fibres within the ureter contained neuropeptide Y-like immunoreactivity (NPY-LI...
The occurrence, distribution and regional variation of neurones immunoreactive for the neuropeptides, vasoactive intestinal polypeptide (VIP), neuropeptide Y (NPY), enkephalin (ENK), calcitonin gene-related peptide (CGRP), and substance P (SP) were investigated in human ureters by indirect immunohistochemistry. In addition, immunoreactivities to ty...
The projections and terminal ramifications of electrophysiologically characterized myenteric neurons of the guinea pig small intestine were studied after intracellular injection of the marker substance biocytin. Myenteric neurons were impaled with microelectrodes containing 4% biocytin in 2 M KCl (pH 7.4) and characterized electrophysiologically as...
Recordings were made from myenteric neurons of the guinea-pig ileum during reflexes evoked by mechanical stimulation of the mucosa. Impaled neurons were injected with dye (Lucifer yellow or biocytin), and their shapes were determined. All neurons were 5-12 mm from the stimulus, a brush stroke that deformed the mucosal villi. Neurons were classified...
The distribution of nerve cells with immunoreactivity for the calcium-binding protein, calbindin, has been studied in the small intestine of the guinea-pig, and the projections of these neurons have been analysed by tracing their processes and by examining the consequences of nerve lesions. The immunoreactive neurons were numerous in the myenteric...
The distribution of nerve cell bodies and fibres with immunoreactivity for gamma-aminobutyric acid (GABA) has been studied in the guinea-pig small intestine. Cell bodies were common in myenteric ganglia but were extremely rare in the submucosa. Reactive fibres were numerous in the tertiary component of the myenteric plexus and in the circular muscl...
The shapes of myenteric neurons in the guinea-pig small intestine were determined after injecting living neurons with the dye Lucifer yellow via a microelectrode. The cells were fixed and the distribution of Lucifer yellow rendered permanent by an immunohistochemical method. Each of 204 nerve cells was examined in whole-mount preparations of the my...
Questions
Questions (2)
Update from a twice-infected patient, myself: I can confirm that Blastocystis causes active clinical symptoms. Tests for all other organisms are consistently negative. On both occasions when I contracted Blastocystis, the symptoms appeared and were the same in both cases, very uncomfortable, reducing quality of life. On both occasions, treatment with Metronidazole, even extended therapy including oral and rectal administration, was totally ineffective.
There was an experiment in which a very thin flat vertical glass tank of water with established laminar flow had nozzles injecting dye at one end. The flow pattern was analyzed. A pattern emerged from turbulence in the form of transient eddies. It was found that the probability of a pattern increased with each instance of it occurring, until it became a stable, enduring formation. I cannot find the experiment anywhere on the internet - can someone point me in the right direction? I've drawn an approx setup from memory of it being shown in operation on a television science show (in the late 80s - early 90s).
