Diana Wolff

University of Tübingen | EKU Tübingen · Department of Conservative Dentistry

Purpose: Part 2 of this German S3 clinical practice guideline provides recommendations for the process of manufacturing composite restorations. It covers key aspects like caries removal, field isolation, matrix and adhesive techniques, as well as light curing and polishing. The outcomes of interest include survival rates and restoration quality....

Purpose: This German S3 clinical practice guideline offers evidence-based recommendations for the use of composite materials in direct restorations of permanent teeth. Outcomes considered were the survival rates and restoration quality and process quality of the manufacturing process. Part 1 of this two-part presentation deals with the indication...

Preterm birth serves as one of the leading causes of neonatal mortality worldwide. The underlying mechanisms that contribute to preterm birth are not yet fully understood. However, an association between periodontitis and preterm birth has been proposed. The periodontal status and presence of periodontal pathogens in women with different birth outc...

Aim Evaluating the clinical survival and quality parameters of class-II restorations using 3M™ FiltekTM Bulk Fill Posterior Restorative compared to 3M™ FiltekTM Supreme XTE Universal Restorative over a period of five years. Materials and methods A longitudinal, randomized, prospective split-mouth study with 60 patients (29 female, 31 male; mean ag...

Background: Omega-6 and omega-3 polyunsaturated fatty acids (PUFAs) are precursors of pro- and anti-inflammatory lipid mediators. Serum PUFA levels could influence the severity of inflammatory oral diseases, such as gingivitis. Objective: The study analyzed serum PUFA levels in a six-week randomized controlled trial in individuals on the Mediter...

Purpose: To evaluate the long-term clinical quality of subgingivally placed composite resin restorations and the inflammatory status of surrounding supracrestal gingival and periodontal tissues. Materials and methods: Patients with at least one subgingival restoration with deep-margin elevation placed between 2010 and 2020 at Heidelberg Universi...

Objective: This retrospective study aimed to evaluate tooth loss and the evolution of periodontal inflammatory parameters within a strict nonsurgically treated patient cohort with < 2 supportive periodontal care visits per year, defined as minimal periodontal basic care, of 2.5 to 10.7 years. Method and materials: Data for nonsurgically treated...

Aim To investigate associations between oral health-related conditions and the oral microbiome in a representative study sample of centenarians. Materials and methods Clinical and microbial parameters from 54 centenarians were assessed in the Heidelberg Dental Centenarian Study. Plaque and salivary samples were collected, and the microbiota was ch...

Objectives The aim of this randomized controlled clinical trial was to evaluate the clinical survival and quality parameters of class-II restorations using a bulk-fill composite resin compared to a conventional nanohybrid composite resin in a split-mouth design. Methods One hundred and twenty direct restorations were placed in stress bearing class...

To date, there is little evidence on centenarians’ dental and prosthetic status or their oral-health-related quality of life (OHRQoL). Therefore, the aim of this study was to assess possible associations between sociodemographic and oral health factors, including prosthetic needs in this special age group and their potential influence on OHRQoL. Pe...

Purpose: The purpose of this multicenter study was to evaluate the survival and quality outcome of direct composite buildups in the anterior dentition based on representative sample sizes. Materials and Methods: At three university clinics in Germany, the survival and quality outcome of n = 667 direct composite buildups performed between 2001 and...

Purpose: This sub-analysis of our multicenter trial was to assess the long-term periodontal health (PH) of teeth, esthetically reshaped by means of direct composite buildups. Materials and methods: 198 patients who received 667 direct composite buildups on 585 treated teeth (TT) between 01/2001 and 12/2013 were included. PH was assessed for each T...

Objectives: There is a lack of comprehensive indexes, which can measure conditions or changes in dento-facial esthetics before and after treatment. Therefore, the 12-item Dental Esthetic Screening Index (DESI) was developed and validated. Materials and methods: Reliability was tested by five dental professionals, who evaluated 30 standardized pa...

Objectives To elicit patterns in pathogenic biofilm composition we characterized the oral microbiome present in patients with dentin caries in comparison to healthy subjects. Methods 16S amplicon sequencing was used to analyse a total of 56 patients; 19 samples of carious dentin (pooled from at least three teeth) and 37 supragingival samples (pool...

Objective:The composition of the oral microbiome differs distinctively between subjects with and without active caries. Still, caries research has mainly been focused on states of disease; aspects about how biofilm composition and structure maintain oral health still remain widely unclear. Therefore, the aim of the study was to compare the healthy...

This 4-year randomized controlled trial (RCT) aimed at investigating whether routine home use of both a SnCl2/AmF/NaF-containing mouth rinse and toothpaste has a preventive effect on oral health. Fifty-four test subjects were examined in biannual intervals. The primary endpoint “dental erosion” was determined by the Basic Erosive Wear Examination (...

Objectives: The aim of this trial was to investigate the diagnostic value of the basic erosive wear examination (BEWE) in clinical use, on dental photographs, and on dental casts over a two-year follow-up period (2013-2015). According to the main hypothesis for longitudinal monitoring of dental erosion, the BEWE is equally reproducible by the thre...

Abstract The aims of this four-year randomized controlled clinical trial were to gain insights into management and prevention of dental caries and the effect of stannous fluoride products in athletes. Fifty-four participants were randomized into test and control groups. The test group used special stannous fluoride products. The primary endpoint de...

Introduction This study aimed to develop a suitable instrument for a comprehensive quantitative and qualitative assessment of perceived psychosocial impact, levels of stress and learning effect in undergraduate dental students during the transition from pre‐clinical to clinical education. These findings might improve curricular structures and didac...

Placement of composite resin restorations in deep subgingival cavities can damage surrounding soft tissues. In addition, commonly used resin-based composites (RBCs) might interfere with wound healing and periodontal health. To clarify cellular interactions with RBCs, we used an MTT assay to investigate adhesion of primary human gingival fibroblasts...

Introduction: Limited access to interdental spaces complicates removal of excess material when placing class II composite resin restorations. Evidence-based recommendations on interproximal finishing are rare. We present novel microscalpels for this indication. The aim of the study was to test their fracture strength and cutting ability and to com...

Statement of problem: Although fiber-reinforced composite fixed dental prostheses (FRC FDPs) are a reliable treatment option for the restoration of single missing teeth, comparatively few prospective clinical trials (PCT) exist. Purpose: The purpose of this PCT was to evaluate the survival, quality outcome, and effect of FRC FDPs on periodontal...

Purpose: To evaluate the effects of aqueous storage on shear bond strength (SBS) and monomer release of fiberreinforced composites (FRCs). Materials and methods: Four unidirectional FRCs were tested, including one semi-interpenetrating polymer network (IPN) (ES, everStick) and three cross-linked polymer (CLP) FRCs (GT, GrandTec; TF, TenderFiber;...

Aim: To compare long-term effects of brushing with an oscillating-rotating power toothbrush or an ADA reference manual toothbrush on pre-existing gingival recession. Materials and methods: In this controlled, prospective, single-blind, parallel group study, healthy subjects with pre-existing recession were randomized and brushed with a power too...

Das Konzept der minimalinvasiven Zahnheilkunde bietet aufgrund der defektorientierten Vorgehensweise günstige Voraussetzungen für die Verwendung von adhäsiv verankerten und plastisch verarbeitbaren Kompositmaterialien. Im Bereich der Zahnerhaltungskunde existieren seit Längerem die faserverstärkten Komposite (FRC). Hierbei werden anorganische Faser...

Restorative rehabilitation of missing single teeth in the posterior dentition is achieved primarily by dental implants or fixed dental prostheses. Here we introduce an uncommon, minimally invasive treatment option in order to close single tooth gaps. The purpose of this study was to evaluate the clinical quality and survival of 45 direct composite...

Current treatment protocols and recent developments in composite resin technology allow for extended indication of direct composite resin restorations. This article presents clinical longterm observations of direct composite resin restorations indicated for primary and replacement therapy, repair restorations, direct crowns, and composite buildups...

Ausgedehnte tief subgingival reichende Defekte im Seitenzahngebiet kommen in der Praxis recht häufig vor, und die Restauration solcher Zähne stellt den Zahnarzt vor technische Herausforderungen. Das Hauptanliegen der Patienten ist in erster Linie der langfristige Erhalt des Zahns bei gutem Nutzen-Risiko- und Nutzen-Kosten-Verhältnis. Allerdings ist...

The aim of this investigation was to give insights into the impact of endurance training on oral health, with regard to tooth erosion, caries, and salivary parameters. The study included 35 triathletes and 35 non-exercising controls. The clinical investigation comprised oral examination, assessment of oral status with special regard to caries and e...

Objective A great benefit of FRC technology is that, in case of minor failure events, restorations can be repaired or reinserted. However, various FRC materials are available, that differ in matrix composition and fiber pre-treatment. The aim of this investigation was, therefore, to evaluate original and repair bond strength of FRC materials. Meth...

Currently, fiber-reinforced fixed dental prostheses (FRC FDPs) are a reliable treatment option for the restoration of single missing teeth in the anterior area. The purpose of this study was to evaluate the survival of direct and semidirect fabricated FRC FDPs in the anterior area and to rate the quality of the outcome. Twenty-four participants (12...

Objective: Currently, there are many fibre-reinforced composites (FRCs) available which differ in the type and volume fraction of fibres, pre-treatment of fibres and matrix composition. The aims of this in vitro investigation were to determine whether there is a difference in biocompatibility of FRCs and if coating FRCs with resin composites influ...

Objective: Patients with RA suffer from a higher risk of periodontal attachment loss and increased oral inflammation. We hypothesize that there are pathogenetic and immunological interactions between these diseases that go beyond impaired manual dexterity accompanying advanced RA. The primary objective of the present study was to determine whether...

Aufgrund der Fortschritte in der Adhäsiv- und Komposittechnologie ist es heute problemlos möglich, ästhetisch ansprechende Rekonstruktionen im Frontzahnbereich mit direkt applizierten Kompositen durchzuführen. Hierfür stehen langzeitstabile Adhäsiv- und Kompositsysteme zur Verfügung. Direkte Restaurationen aus Kompositen im Sinne von Zahnformkorrek...

Objective: Several studies reported that patients with rheumatoid arthritis (RA) suffer from a higher risk of periodontal attachment loss and increased oral inflammation. It is discussed that there are pathogenetic and immunological interactions between both diseases which go beyond impaired manual dexterity accompanying advanced RA as etiologica...

Adhesive resin composite technology enables dentists to add composite material to tooth surfaces to close gaps and reshape tooth form without cavity preparation. This option creates new possibilities for minimally invasive dentistry as the tooth shape, position and colour can be altered without loss of tooth substance. However, evidence-based data...

SUMMARY Provided that moisture control is possible, today's resin composite materials can be applied successfully in the restorative treatment of extensively decayed teeth. This suggests that restorative margins will be increasingly located below the cementoenamel junction, probably invading biological width. The recently introduced technique of pr...

Background: Certain major pathogens such as Streptococcus mutans, Lactobacillus spp. and others have been reported to be involved in caries initiation and progression. Yet, in addition to those leading pathogens, microbial communities seem to be much more diverse and individually differing. The aim of this study, therefore, was to analyze the bact...

The authors conducted a literature review to determine how dentofacial esthetics can be evaluated in restorative dentistry and which quantifiable clinical parameters can be used for this assessment of dentofacial esthetics. The authors selected 35 studies that focused on assessment strategies for dental professionals. The primary inclusion criteria...

The aim of the study was to test whether a novel three-step matrix technique for posterior direct-composite additions creates sufficiently strong proximal contacts. Contact tightness was measured between direct-composite additions and between original teeth on a model. Therefore, the frictional forces required to remove a straight, 0.05-mm-thick, m...

The aim of the study was to analyze the dissolving depth of adhesive resin monomers into pre-polymerized fiber-reinforced composites (FRC) with either a semi-interpenetrating polymer network (semi-IPN) or a cross-linked polymer (CLP) matrix. Five unidirectional FRCs were tested, including one semi-IPN FRC (everStick(®) C&B, StickTech, (ES)) and fou...

An objective structured clinical examination (OSCE) has been implemented in preclinical dentistry. It was taken at an early stage (propaedeutics course). The objectives of this study were to evaluate the reliability, validity, and feasibility of the examination, and the effect of circuit number on OSCE score. The OSCE was designed by an expert comm...

Objective: Case report presents dental treatment of oral inflammation and subsequent reduction of symptoms of active rheumatoid arthritis (RA). Methods: Male Patient was diagnosed with highly active anti-CCP-negative RA in 2010-06. He reported morning stiffness and pain in fingers, hip and shoulders. Finger joints were swollen. Health-assessment-qu...

Objective: The aim of the study was to test whether the application of a novel triple-step matrix technique for posterior direct composite additions allows for the reconstruction of sufficient proximal contacts points. Methods: The contact strengths were measured between direct composite additions and between original teeth on a model. Therefore, f...

Objectives: The aim of the study was to compare the penetration of an adhesive into fiber-reinforced-composites (FRC) with either interpenetrating-polymer-network (IPN) or cross-linked-polymer (CLP) matrix. Methods: 5 materials were tested including one IPN-FRC (everStick-C&B, StickTech) and four CLP-FRCs (GrandTec,VOCO; Dentapreg, ADM; TenderFib...

Objectives: The aim of the study was to evaluate the cleaning efficacy and the forces necessary for insertion of novel triangular interdental-brushes (TIB, n=4) and conventional round interdental brushes (RIB, n=4). Methods: Extracted human teeth were fixed in a socket and matched to pairs in a reversible and reproducible manner, simulating small...

Objective: The aim of the study was to establish and validate a quantitative real-time PCR assay (RQ-PCR) for typing a broad spectrum of caries and health associated oral bacteria. Methods: 140 PCR primers for relevant caries and health associated species were designed by aligning primer sequences against data from the Ribosomal Database Project an...

Irregular tooth shape and position in the anterior maxilla and mandible are major aesthetic problems for patients. In recent years such conditions have increasingly been treated minimally or even non-invasively by recontouring teeth with direct composite resin buildups. Although clinical experience with this treatment option is promising, evidence-...

High-throughput technologies for typing caries or health-associated bacterial populations including PCR, DNA microarrays and next-generation sequencing techniques require significant amounts of bacterial DNA. In clinical settings, the amount of sampled DNA is often limited and amplification is therefore essential. Protocols should be able to reprod...

The use of mineral trioxide aggregate (MTA) might improve the prognosis of teeth after pulp exposure. The treatment outcome of teeth after direct pulp capping, either with mineral trioxide aggregate (MTA) or calcium hydroxide (controls), was investigated, taking into account possible confounding factors. One hundred forty-nine patients treated betw...

To obtain survival data on 32 fiber-reinforced fixed dental prostheses which were inserted in our department and to rate the quality of these restorations on the basis of esthetic, biological, and functional parameters. Thirty-two patients with fiber-reinforced fixed dental prostheses were included in the study. The fiber frameworks were made of a...

"Submicron hiatus" represents a potential space between the base of the collagenous network and the mineralized dentin when it is acid etched for bonding. This study evaluated the relationship between microtensile bond strength (microTBS) and occurrence of submicron hiatus formations at the resin-dentin interface using the same specimens. Resin-den...

To evaluate gingival recession changes after six months of brushing with an oscillating-rotating power toothbrush (PT) or an ADA reference manual toothbrush (MT). Healthy subjects with pre-existing recession were assigned to brush with either a PT (n=55) or an ADA reference MT (n=54) according to a prospective randomized, controlled, single-blind,...

This study evaluated the relationship between microtensile bond strength (microTBS) and occurrence of nanoleakage at the resin-dentin interface using the same specimens. Resin-dentin-bonded micro-specimens (sticks with a size of 300 microm x 300 microm x 8mm) were prepared using one of two material combinations (group I: Syntac classic/Tetric Ceram...

The aim of this study was to compare the resistance to insertion forces and cleaning efficacy values of triangular interdental brushes (TIB) and conventional round interdental brushes (RIB). Extracted human teeth were fixed in a socket and matched to pairs simulating interdental spaces. Before and after standardized cleaning of the proximal surface...

The purpose of this study was to evaluate both reliability and validity of the assessment of the shape of the mandibular condyle in panoramic images of the TMJ. Forty subjects were included and were examined according to the Research Diagnostic Criteria for Temporomandibular Disorders. Panoramic radiographs (PRs) and magnetic resonance images (MRIs...

The aim of this study was to evaluate the cleaning efficacy of interdental brushes with different stiffnesses, e.g. soft and hard interdental brushes with identical brush diameter. Cylindrical soft and hard interdental brushes with diameters of 2,3 and 5 mm each were tested. Sixteen extracted human molars were fixed in split cast models to simulate...

We report on 82 patients who had segmental resection of the mandible and immediate reconstruction with titanium plates, which were supplemented by polymethylmethacrylate cement (n=32), glass ionomer cement (n=27), silicone (n=9), or nothing (n=14). The mean (S.D.) follow-up time was 92 (26) months. Six months after operation, 27 (46%) of the plates...

AIM: The aim of this retrospective study was to investigate whether radical (segmental resection) or conservative (marginal) resection of mandibular bone influenced patients, survival. PATIENTS AND METHODS: A series of 136 patients selected for partial mandibular resection for the treatment of squamous cell carcinomas of the lower oral cavity was e...

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Heidelberg, Univ., Diss., 2004.