Diana Cimpoesu

• Professor
• Head of Emergency Department at Grigore T. Popa University of Medicine and Pharmacy

Background and Objectives: The incidence and prevalence of cancers are increasing worldwide, with special emphasis placed on prevention, early detection, and the development of new therapeutic strategies that strongly impact patient outcomes. Limited data are available about emergency care’s role in treating patients with cancer. This study aims to...

Burnout and stress-related issues are significant concerns among medical personnel involved in emergency situations due to the high demands of their work. A cross-sectional descriptive and comparative study was conducted on 266 prehospital emergency personnel across five Romanian counties, comprising 41 physicians, 74 nurses, and 151 paramedics. Da...

This study explores the antibacterial efficacy and cytotoxicity of ciprofloxacin-functionalized bioceramic implants. We synthesized hydroxyapatite-ciprofloxacin (HACPXCS) composites and applied them to titanium substrates (Ti-HA-CPX), evaluating their performance in vitro against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922)....

Trauma, a global health challenge, remains a significant cause of mortality despite advances in trauma management. The establishment of trauma teams has revolutionized care in trauma resuscitation. The training of these teams is designed to promote self-trust and empower trainees in trauma care, enhance performance, and improve patient outcomes. Va...

Aim of the study This qualitative study explores the resilience of medical staff working in emergency units during the COVID-19 pandemic. Through in-depth interviews and thematic analysis, the research investigates how frontline healthcare workers coped with unprecedented challenges. Key themes identified include professional commitment, teamwork,...

Background The aim of this study was to determine the incidence, clinical and paraclinical characteristics and outcomes of Covid-19 positive patients presenting in the Emergency Department (ED) with and treated for acute limb ischaemia (ALI) during a 2-year period. Methods This retrospective study was conducted in the ED of St. Spiridon County Cli...

Background and importance In 2018, the European Society of Cardiology (ESC) produced syncope guidelines that for the first-time incorporated Emergency Department (ED) management. However, very little is known about the characteristics and management of this patient group across Europe. Objectives To examine the prevalence, clinical presentation, a...

The use of Automatic External Defibrillators (AED) present in public access defibrillation programs (PAD) in cardiopulmonary resuscitation (CPR) is a challenge in the effective treatment of cardiac arrest, especially for adult patients. It is already known that the majority of adult cases of out-of-hospital cardiac arrest arise from ventricular fib...

According to the latest international resuscitation guidelines, extracorporeal cardiopulmonary resuscitation (ECPR) involves the utilization of extracorporeal membrane oxygenation (ECMO) in specific patients experiencing cardiac arrest, and it can be considered in situations where standard cardiopulmonary resuscitation efforts fail if they have a p...

Background Contemporary scientific literature has emphasized two specific aspects of healthcare professionals: compassion satisfaction and compassion fatigue. In the context of the COVID-19 pandemic, which has placed significant strain on health systems and healthcare workers, the Russian-Ukrainian crisis appears to have a magnifying effect, partic...

Background: Upper gastrointestinal (GI) bleeding is a life-threatening condition with high mortality rates. Aim: To compare the performance of pre-endoscopic risk scores in predicting the following primary outcomes: In-hospital mortality, intervention (endoscopic or surgical) and length of admission (≥ 7 d). Methods: We performed a retrospecti...

Worldwide, during COVID-19 pandemic, the healthcare professionals have been exposed to professional and existential stress. The aims of this study were to evaluate of the emotional impact, the degree of resilience of medical staff, immediately after exposure to the risk of COVID-19. Material and methods: e enrolled 64 participants (30 doctors and 3...

Background Severe trauma represents a major global public health burden and the management of post-traumatic bleeding continues to challenge healthcare systems around the world. Post-traumatic bleeding and associated traumatic coagulopathy remain leading causes of potentially preventable multiorgan failure and death if not diagnosed and managed in...

(1) Background: The perfusion index (PI) represents the ratio between pulsatile blood flow and non-pulsatile blood flow in the peripheral tissue. (2) We aimed to investigate the blood pressure perfusion of tissues and organs in ethnobotanical, synthetic cannabinoid and cannabis derivative consumers through the value of perfusion index. (3) Results:...

(1) Background: Poisonings in children are common reasons for addressing ED and can potentially have serious complications. Our research aims to review risk factors leading to poisoning in children. (2) Methods: A retrospective review of all pediatric poisoning cases addressing the Children’s emergency department of St Mary Hospital over a two-year...

ESCAPE-NET and PARQ: a continuity for resuscitation science PARQ aims to create a network of researchers across Europe whose overall aim is to reduce the societal burden of sudden cardiac arrest (SCA). To reach this aim, PARQ will conduct studies that focus on two dimensions: (1) prevention of SCA through the discovery of its inherited, acquired, a...

(1) Background: The aim of the current study is to identify the relations between worries, threat perceptions, anxiety states, and general health in a sample of Emergency unit staff during the Russian Ukrainian armed conflict. The sample consisted of 372 Emergency Care staff (M age = 39.41; 77.2% women), physicians, and nurses from North-eastern Ro...

Background: Unnecessary resuscitation is defined as putting in a disproportionate amount of effort compared to the patients' prognosis and chance of survival. The primary objective of this study was to determine the number of resuscitations perceived as unnecessary by emergency medical personnel and to correlate it with the characteristics of resu...

Drones have evolved significantly in recent years, acquiring greater autonomy and carrier capacity. Therefore, drones can play a substantial role in civil medicine, especially in emergency situations or for the detection and monitoring of disease spread, such as during the COVID-19 pandemic. The aim of this paper is to present the real possibilitie...

Background Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure patients’ ED management and short-term outcomes. Methods This was a sub-analysis of a European EURODEM study. Data on patient...

Objective: The aim of this current study was to identify the prevalence of burnout manifestation in a sample recruited from the emergency department of a hospital. Moreover, we aimed to assess the role of professional experience, age, and the professional category in shaping burnout manifestations. Results: The results showed that higher proport...

Background Despite the severity of ethylene glycol intoxication, there is a paucity of studies that analyze prognostic factors. This study aims to determine prognostic factors with impact on core outcomes like death and prolonged kidney injury (KI) in ethylene glycol poisoned patients. Methods We retrospectively assessed prevalence, clinical and b...

Introduction: The rapid use of an automated external defibrillator (AED) is crucial for increased survival after an out-of-hospital cardiac arrest (OHCA). Many factors could play a role in limiting the chance of an AED use. We aimed to verify the situation regarding AED legislation, the AED mapping system and first responders (FRs) equipped with a...

Emergency Medicine - out of hospital and in hospital: CPR, trauma, disaster, cardiovascular emergencies, respiratory emergencies, abdominal emergencies

The European Resuscitation Council has produced these first aid guidelines, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics include the first aid management of emergency medicine and trauma. For medical emergencies the following content is covered: recovery posi...

Informed by a series of systematic reviews, scoping reviews and evidence updates from the International Liaison Committee on Resuscitation, the 2021 European Resuscitation Council Guidelines present the most up to date evidence-based guidelines for the practice of resuscitation across Europe. The guidelines cover the epidemiology of cardiac arrest;...

The European Resuscitation Council (ERC) has produced these Systems Saving Lives guidelines, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The following topics are covered: chain of survival, measuring performance of resuscitation, social media and smartphones apps for e...

Background Survival after out-of-hospital cardiac arrest (OHCA) is still low. For every minute without resuscitation the likelihood of survival decreases. One critical step is initiation of immediate, high quality cardiopulmonary resuscitation (CPR). The aim of this subgroup analysis of data collected for the European Registry of Cardiac Arrest Stu...

The aim of this study was to assess the delays that can potentially occur in the emergency transfer of patients with ST-elevation myocardial infarction (STEMI) to percutaneous coronary intervention (PCI) centers. We conducted a retrospective study using the medical reports pertaining to 97 patients who presented to the Emergency Department of the E...

The European Resuscitation Council (ERC) has produced these Systems Saving Lives guidelines, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics covered include chain of survival, measuring performance of resuscitation, social media and smartphones apps for engaging...

The European Resuscitation Council has produced these first aid guidelines, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics include the first aid management of emergency medicine and trauma. For medical emergencies the following content is covered: recovery posi...

"Abstract: Stroke has a significant prevalence in Romania. The predisposition for this multifactorial disease is partially known. The aim of this study is to investigate the predisposition for stroke in Romanian population. Material and methods. We selected cases with recent ischemic stroke (n=100) and healthy control subjects (n=100). The AGTR1 A1...

Background: In Europe, survival-rates after out-of-hospital cardiac arrest (OHCA) vary widely between regions. Whether a system dispatching First Responders (FRs; main FR-types: firefighters, police officers, citizen-responders) is present or not may be associated with survival-rates. This study aimed to assess the association between having a disp...

Abstract Introduction Cardiopulmonary resuscitation (CPR) in patients with a poor prognosis increases the risk of perception of inappropriate care leading to moral distress in clinicians. We evaluated whether perception of inappropriate CPR is associated with intention to leave the job among emergency clinicians. Methods A cross-sectional multi-...

Pediatric comas are particular situations of terrestrial or aerial medical intervention, requiring knowledge of specific protocols and prioritization and hierarchy of emergency interventions. The reactivity of the comatose child is modified according to multiple biological, physiological parameters and generating pathologies. The study aims to anal...

BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are common in emergency departments (ED). Guidelines recommend administration of inhaled bronchodilators, systemic corticosteroids and antibiotics along with non-invasive ventilation (NIV) for patients with respiratory acidosis. AIM: To determine compliance with guideline re...

Background: The epidemiology and outcome after out-of-hospital cardiac arrest (OHCA) varies across Europe. Following on from EuReCa ONE, the aim of this study was to further explore the incidence of and outcomes from OHCA in Europe and to improve understanding of the role of the bystander. Methods: This prospective, multicentre study involved th...

Objectives: To determine the prevalence of clinician perception of inappropriate cardiopulmonary resuscitation (CPR) regarding the last out-of-hospital cardiac arrest (OHCA) encountered in an adult 80 years or older and its relationship to patient outcome. Design: Subanalysis of an international multicenter cross-sectional survey (REAPPROPRIATE)...

Background: In Europe, survival rates after out-of-hospital cardiac arrest (OHCA) vary widely. Presence/absence and differences in implementation of systems dispatching First Responders (FR) in order to arrive before Emergency Medical Services (EMS) may contribute to this variation. A comprehensive overview of the different types of FR-systems use...

Background: Cardiopulmonary resuscitation (CPR) in special circumstances includes the emergency intervention for special causes, special environments, and special patients. Special causes cover the potential reversible causes of cardiac arrest that must be identified or excluded during any resuscitation act. The special environments section includ...

Background: Acute pulmonary embolism (PE) requires rapid diagnosis and early and appropriate treatment, often under conditions of hemodynamic instability. The therapeutic strategy should optimally integrate the therapeutic arsenal in a multidisciplinary but unitary approach. Areas of uncertainty: The short list of the major uncertainties associa...

Benzodiazepines represents a large category of medications that were originally developed to treat anxiety disorders or issues with anxiety, seizures, and issues with sleeping. The most common drugs abused along with benzodiazepines are other benzodiazepines, prescription pain medications and alcohol. Alcohol and benzodiazepine have a synergistic d...

Plant extracts with antimicrobial potential are an important research directive in the current medical world, aiming to isolate active components in order to develop new chemotherapeutic agents that can be used in the treatment of various infectious disease. In the present study we determined the content of polyphenol carboxylic acids and flavonoid...

ABSTRACT Introduction Cardiopulmonary resuscitation (CPR) is often started irrespective of comorbidity or cause of arrest. We aimed to determine the prevalence of perception of inappropriate CPR of the last cardiac arrest encountered by clinicians working in emergency departments and out-of-hospital, factors associated with perception, and its re...

Very often disasters result in mass casualty situations, which trigger a complexity of decisions to be made at collection points and advanced medical posts by local health services. The decision-making process becomes complicated because of significant bleeding into the peritoneal, pleural, or pericardial spaces may occur without visible warning si...

Statins are a class of lipid-lowering medications that reduce cardiovascular disease and mortality in pacients who are at high risk. The molecular docking technique has become an increasingly important tool for drug discovery which help us understand the most stable conformations resulting from ligand-active site of the biological receptor interact...

Pain is defined as a disagreeable sensory and emotional experience related to a tissue or potential lesion. Paracetamol (Acetaminophen) is the most used non-morphine analgesic. For the determination of paracetamol we developed and validated the high performance liquid chromatography (HPLC) analysis using a Dionex Ultimate 3000 liquid chromatograph...

In the era of transition from "classic" Cardiopulmonary resuscitation (CPR) to assisted device-CPR or hemodynamic driven CPR, the present book, published by "InTechOpen", highlights some interest aspects of resuscitation. Divided in three sections, it passes from emphasizing details of resuscitation in special circumstances to possible future appli...

Aim To assess the time to connect the telephone call to emergency medical dispatch. Methods Regional randomised study as a part of a prospective, multicenter study was conducted in April 2013 within the Medical Dispatch, Iasi, Romania. The distribution of the 112 calls followed a diurnal distribution using a computer generated sets of random numbe...

Background: Acute pulmonary embolism (PE) is a major cause of cardiac arrest with a high in-hospital mortality rate. If a fibrinolytic drug is given in these circumstances, survival and good neurological outcome have been reported in some cases although a study powered to reach significance has not yet been conducted. Methods: We are planning a pro...

Objective: Sepsis is a common syndrome with devastating implications for health care systems worldwide. Biomarkers may play an important role in highlighting the presence, absence or severity of sepsis. Materials and methods: This study is an retrospective study, performed on patients with suspected sepsis (81 patients) from a total of 10,483 patie...

Aim: In out of hospital cardiac arrest (OHCA) a single rescuer should start with Cardiopulmonary Resuscitation (CPR) immediately after calling the Emergency Medical Communication Centre (EMCC). The start of CPR may be delayed considerably if the total time to connect to the dispatcher at the EMCC (TT-EMCC) is prolonged. EUROCALL aimed to investiga...

The authors regret that the following contributors were not acknowledged in the original manuscript: Ondrej Franek (Czech Republic); Nuria López Cabeza (Spain); José M. Navalpotro Pascual (Spain). The authors would like to apologise for any inconvenience caused.

Aim: Suicide is a global health problem with an increasing incidence among young adults and teenagers. The study was aimed at analyzing the profile and identifying the frequency, nature, and contributing factors of suicides. Material and methods: This retrospective study included all patients who attempted suicide admitted to the Emergency Depar...

Aim: The study aimed to identify the risk factors and the particularities of ethnobotanicals and cannabis users who needed medical care in the Emergency Department of the „Sf. Spiridon” County Hospital. Material and methods: Retrospective study conducted over a period of 18 months (January 1, 2015- June 30, 2016). This study included all patient...

Suicidal behavior can be prevented by attending psychotherapeutic, pharmacological or neuromodulator treatments for mental disorders.

Teaching cardiopulmonary resuscitation in Romanian schools is a joint initiative of the Acute Cardiac Care Working Group of the Romanian Society of Cardiology, the Romanian National Resuscitation Council and the Romanian Society of Emergency Medicine and Disaster. Teaching young generations to save people in cardiac arrest requires a structural app...

The aim of the EuReCa ONE study was to determine the incidence, process, and outcome for out of hospital cardiac arrest (OHCA) throughout Europe. This was an international, prospective, multi-centre one-month study. Patients who suffered an OHCA during October 2014 who were attended and/or treated by an Emergency Medical Service (EMS) were eligibl...

Drawings made by training children into cardiopulmonary resuscitation (CPR) during the special education week called “School otherwise” can be used as non-verbal means of expression and communication to assess the impact of such training. We analyzed the questionnaires and drawings completed by 327 schoolchildren in different stages of education. A...

AIM: The objective of this study is to evaluate divalent cations serum levels (magnesium, zinc, copper) in liver cirrhossis and one of its major complication (variceal bleeding).

Sepsis syndrome is a common situation and has devastating implications on health care systems worldwide. Biomarkers may have an important role to highlight the presence, absence or severity of sepsis. Retrospective study is conducted on a group of 95 suspected sepsis patient (0.16%) out of a total of 56,996 patients that were presented in the Emerg...

Emergency medicine as a medical specialty has to deal with all kind of emergency situations, from medical to post traumatic acute eyents and from new born to the elderly persons, but also with particular situations like explosions. In Romania nowadays these are accidental explosions and rare like frequency, but may be dramatic due to numbers of vic...

Romania ranks fourth in the world for the consumption of ethnobotanical products, behind England, Germany and the Netherlands, although in 2008, our country was not in the ranking. The study intends to identify the substances contained in ethnobotanical products. This was possible using gas chromatography-mass spectrometry. The results revealed the...