Deyala Naguib

• Associate professor of Plant Physiology
• Professor (Associate) at Al Baha University

There is a shortage in the experimental research directly comparing the effectiveness of different nanoparticles in boosting asparaginase (ASNase) activity. This study assessed the impact of various nanoparticles on enhancing ASNase activity, stability, and anticancer effects through immobilization. Escherichia coli ASNase was immobilized on differ...

Antibiotic resistance poses a global health threat. It reduces the effectiveness of antibiotics against bacterial infections. Antimicrobial peptides, including thionins, offer a promising alternative due to their broad-spectrum activity and lower likelihood of resistance development. This study focuses on the production of thionin from barley cell...

Few researches have explored the production of pharmaceuticals from aquatic plants. Therefore, this study explored, for the first time, the phytochemical composition and bioactivities of ten aquatic plants. Aquatic plant shoots from various Nile River canals were collected, dried, and ground for aqueous extract preparation. Phytochemical compositio...

Heavy metal pollution is a serious environmental problem. Most of the current techniques used to mitigate the toxic effects of heavy metals have limitations. This creates an urgent need to explore safer and more efficient methods to address these toxic effects. This study investigates the potential of nano-water hyacinth protein (nano-WHP) as an ad...

This research addresses the urgent global need for the safe and economical removal of dyes from wastewater. We assessed the efficacy of polyphenol oxidase (PPO) extracted from different agricultural residues in removing reactive blue dye, marking the initial endeavor to do so. PPOs isolated and refined from rice straw, corn stover, peanut peels, ol...

Aim This study aims to evaluate the impact of seed primimg with soil microorganism on the germination and metabolism of pearl millet seeds when exposed to the allelopathic effects of some specific weed extracts. Methods Pearl millet seeds were categorized into five distinct groups. Four of these groups were subjected to priming with different soil...

Fungal pathogens cause over a billion human infections annually, leading to more than 1.6 million deaths each year. The scarcity of available antifungal drugs intensifies the public health threat posed by human pathogenic fungal infections. Therefore there is a critical demand for novel, safe, and effective antifungal agents. Although chitinases ar...

Bio-priming is a proven method for enhancing seed germination in stressful environments. Researchers have thoroughly explored its impact on enzyme activity during seed germination under diverse environmental stresses. Yet, there is limited knowledge about how bio-priming specifically influences enzyme kinetics. Understanding these kinetic changes c...

The present study aims to investigate the physicochemical characteristics of phenylalanine ammonia-lyase (PAL) extracted from agricultural waste and its potential use as an anticancer agent in comparison to microbial PAL. We extracted and partially purified PAL from agricultural waste sources. We assessed the temperature and pH range of PAL and det...

Antibiotic-resistant pathogenic bacteria and the oxidative stress related to their infections are dangerous health problems. Finding new safe, effective antibacterial and antioxidant agents is an urgent global need. Probiotics are a strong candidate for possible antibacterial and antioxidant agents. The delivery of these probiotics without any effe...

We aim to find a simple agricultural waste processing method to improve soil water retention and soil enzymes vitality, control soil-borne pathogens, and enhance plant resistance against biotic stress. We extracted polysaccharides from different agricultural wastes. We tested the antimicrobial activity of the extracted polysaccharides on different...

Agriculture activities industries produce a huge amount of waste every year. Agricultural wastes are a great source of natural polysaccharides characterized by accessibility, biocompatibility, and ease of modification. Finding new safe antibacterial agents has become one of the top priorities of health organizations worldwide. This priority emerged...

The plants exert rapid responses to environmental stresses to adapt with the stress. Plants respond in many ways to different abiotic and biotic stresses. The first cellular component to sense stress signals is cell membrane. Cell membrane is a biological membrane, and its main constituents are Lipids that can sense conditions outside the cell. Rem...

Salvadora persica (SP) is an important medicinal plant. Numerous articles have been conducted on the leaf, the roots, and the stem of the plant, but there is little information about the seed. Thus, the present work tries to identify the chemical composition of SP seed bio-oil and investigates its use as an adsorbent for cyclohexane removal. This s...

Intercropping is a tried-and-true approach for restoring depleted agricultural soils, making better use of resources, controlling pests and disease, and ultimately boosting crop yield by reducing soil disease. This study tries to evaluate the role of tomato potato onion intercropping in induction tomato resistance against the soil-borne pathogen, F...

Excessive and frequent usage of synthetic fungicides has negative effects on the environment and human health. Biological control is one of the most efficient and environmentally responsible ways to manage plant diseases. In the present study, Bacillus velezensis strain B63, Bacillus subtilis subsp. Spizizenii strain TRC-20S and Serratia sp. Showed...

Background Colorectal cancer (CRC) is one of the most common causes of cancer death in the world. Although genes are considered the most importantcauses that contribute to CRC, the intestinal microorganisms are an important player. Recently, various studies ensured the role of microbial infection and the ensuing inflammation in colon cancer initiat...

The considerable effect of enzymes on human health draws great attention to enzyme-based drugs (therapeutic enzymes), in recent times. L-asparaginase (ASNase) is a well-known therapeutic enzyme. It has varied applications and is a single molecule for the treatment of multiple diseases. This study tries to extract asparaginase from soybean debris (a...

The soil enzymes are the heart of the biochemical reactions that occur in the soil saving the soil nutrients needed for plant growth. Recently yeast's importance as plant growth-promoting microorganisms has great attention. This study evaluated the effect of yeast application on the soil enzymes activity and root metabolic status in corn plants und...

Seed germination is one of the most critical and complex physiological stages in the plant life cycle. It is highly affected by environmental stress. Priming is a promising tool for the improvement of the plant withstanding against different biotic and abiotic. Most studies that deal with the evaluation of the role of priming on germination evaluat...

Background Onion (Allium cepa) is very rich in nutritional and pharmaceutical components, such as saponins, tannins, alkaloids, steroids, and phenols. Many recent researches approved its anticancer activity against various cancer cell lines. In this paper, we attempt to improve its anticancer activity with encapsulation on nano chitosan. On the bes...

The original version of this article unfortunately contained a mistake in the author group section. The correct name of the first author is “Abdulrahman Ali Alzandi.” The original article has been corrected.

Background Gastrointestinal cancers are the most dangerous cancers all over the world. The gut microbiota dysbiosis increases the risk of GI cancers and induces the host’s susceptibility to carcinogenic bacteria. Antibiotic resistance is rising in these bacteria. Thus, discovering new safe and effective antibacterial agents is a worldwide concern....

Water is the secret of life. The earth is the only planet on which there is life because of water. Therefore water saving should be on the top of our priority. Industries contribute to water pollution hugely with various pollutants varied from large objectives to micro molecules such as heavy metals. Water pollution affects growing plants, animals,...

Colorectal cancer (CRC) is one of the most common causes of cancer death in the world. Although genes are considered the most important causes that contribute to CRC, intestinal microorganisms are an important player. It is proved that microbial infection has a great role in colon cancer initiation and progression. This present study tries to evalu...

Objectives Pancreatic cancer is one of the malignant tumors in the digestive system all over the world. It has a very low survival rate. Although there is a great advancement in its therapy either through radiotherapy, chemotherapy, or other therapies, the overall survival is still less than 24 months. Another problem for pancreatic cancer is the r...

Objectives To discover new natural effective anticancer agents and new antibacterial agents against antibiotic-resistant bacteria which are the most serious public health concern. Another important concern is drug delivery which is the transport of pharmaceutical compounds to have a therapeutic effect in organisms having a disease. Azurin is a prom...

Medicinal plants have a great role in influencing health all over the world. There are few studies for the phytochemical investigations in medicinal plants were conducted in Saudi Arabia especially in Albaha region in south-western Saudi Arabia. Therefore this study focused on the detection of the phytochemical composition of the most dominant eigh...

Fusarium oxysporum is one of the most common soil borne pathogens over the world. This work tried to introduce safe and efficient agent in controlling this pathogen infection in cucumber plants, beside that understanding the mechanism at which fabitine enables the cucumber plants to fight wilt disease. Also, this works introduce a molecular modelin...

Background: Salinity is one of the main threats that can cause crop yield losses by limiting plant growth. Several important cultivated crops including wheat exhibit sensitivity to salt stress by severe yield reductions. Approaches to improve salt resistance are critical for improved food production in the future. Aims: Silicon (Si) is well known f...

Nowadays there is an urgent need for using the natural resistance elicitors due to the numerous problems caused by the chemical ones and these natural elicitors can be used in organic agriculture. This study examines the ability of onion dry scale extract to enhance the resistance in eggplant against bacterial wilt. This evaluation was performed th...

The induction of secondary metabolites under osmotic stress is well documented. However, cell death is probably due to osmotic stress. This work tries to study the synergetic effect of hydropriming and polyethylene glycol (PEG) on enhancing the secondary metabolites production in fenugreek callus cultures without facing cell death. PEG initiates th...

Priming is a safe, easy, and effective way to increase plant tolerance against stress. This research aims to study the metabolic status of the nano-silica-primed germinated maize seeds under salinity stress. We prepare the nano-silica solution (10 mg/ml) from rice straw. We primed group maize seeds with nano-silica solution and the other group rema...

Phenols are very dangerous contaminants found in wastewater. Discharge of these compounds without treatment is highly serious risks to living organisms. The present study offers new effective immobilized peroxidase for phenol removal from wastewater. Nano peroxidase particles were prepared through immobilization of peroxidase enzyme extracted from...

Fruits peels are considered one of the most waste products of food industry. In this paper we attempt to get useful of these peels with low cost methods. We prepared aqueous extract of peels of apple, banana, guava, kiwi, lemon, mango, orange, papaya, pomegranate and watermelon. The anticancer activity of the extracts against different cell lines w...

This study aimed to utilize Pseudomonas fluorescens metabolites as biopriming agent for induction systemic resistance against Fusarium wilt in tomato plants. Two groups of tomato seeds were used, the first was kept dry and the second was primed with Pseudomonas fluorescens metabolites and planted under Fusarium infection conditions. The primed grou...

The resistance mechanism of plants against diseases includes many molecules. This work tries to study role of lipids in the resistance mechanism of eggplant against Fusarium wilt disease. Two eggplant cultivars, the first alabaster, which is susceptible to Fusarium wilt, the second is alabaster F1 which is resistant to Fusarium wilt, were grown und...

Trigonella foenum has a role in cancer treatment. This study tries to evaluate the effect of germination on the anticancer activity of fenugreek seeds. We prepared a dry and germinated aqueous extract from fenugreek seeds. We investigated the growth inhibitory effect of both extracts on MCF7 human breast and Pancreatic (AsPC-1) cells. Fenugreek ext...

This work collects the most important information about the plant immune response. This is very useful for studying phytopathology. It is valuable work in understanding how plants identify different pathogens. The signal transduction pathway. The induction of plant defense genes. plant structures involved in defense against pathogen. plant defense...

The exogenous application of natural plant resistance inducer is a new interesting way for disease management. From this point of view, this study investigated the effect of wheat grain priming with defensin on the resistance of the grown plants against the Fusarium wilt. The results showed that priming enhanced the antioxidant system represented i...

This work tries to study the effect of the cotton seed hydropriming on its metabolic status during germination. Two groups of cotton seed (primed with water and non-primed) were germinated for 7 days. Through this period; the antioxidant enzymes, H2O2, Malonyl dialdehyde, lipid hydrolysis, shikimic acid, aldolase, and the isocitrate lyase were dete...

Silicon (Si) is an abundant macro-element in the soil that helps plants tolerate environmental stress conditions and can ameliorate soil conditions. In this work, we studied the effects of Si ions and silica nanoparticles (both extracted from rice straw) on the physiological and biochemical responses and the expression of the two silicon uptake gen...

In the recent years, the looming food scarcity problem has transformed plant sciences as an emerging discipline committed to devise new strategies for enhanced crop productivity. The major factors causing food scarcity are biotic and abiotic stresses which substantially limit crop productivity worldwide. For enhancing the crops productivity under t...

SALINITY and wilt disease are of the most popular stress conditions that face crops specially rice, our study aims to evaluate biochemical response of rice plants to wilt disease and salinity stress under silica ions and nanoparticles application. Rice plants grew under Fusarium infection (wilt disease) stress and irrigated with five different conc...