Devinder Singh Sandhu

• Doctor of Medicine
• Consultant Medical Oncologist at Sandhu Cancer Centre, Ludhiana

Background: Geographic variations with regard to incidence, clinical presentation, and histological subtypes are known to occur in several cancers. This study was aimed to see if similar differences existed in non-Hodgkin's lymphoma (NHL) also during pre-immunohistochemical era. Materials and Methods: Cases of NHL seen at Institute Rotary Cancer Ho...

Background: Stressful states are known to impair immune function of the body. Impaired immune system and cancer are interrelated, each predisposing to the other. Relaxation techniques, by relieving stress, are expected to restore immune function to normalcy. Sudarshan Kriya and Pranayam (SKP) is a composite relaxation technique based on rhythmic br...

Struma ovarii is a rare ovarian tumor characterized by the presence of mature thyroid tissue. Struma ovarii of the ovary constitutes about 1% of all ovarian tumors. Approximately 15% of ovarian teratomas contain a small, non-significant focus of thyroid tissue, and 0.8-3% are characterized by the presence of functional thyroid tissue or thyroid tis...

We report an 11-year-old child who presented with an abdominal lump and was diagnosed as having an extragonal primary mesenteric seminoma. Patient was treated with 4 cycles of combination chemotherapy cisplatin, etoposide and bleomycin; he is now disease free for 2 years. We discuss and review extragonadal germ cell tumors arising from the mesenter...

Effect of rhythmic breathing (sudarshan kriya and pranayam) on immune functions and tobacco addiction. Ann N Y Acad Sci. 1056:242-52. Stress affects different systems in the body, including the immune system and the endocrine system, and thereby affects the whole physiology. Stress is also linked to the habit of tobacco consumption and substance ab...

Primary mammary osteosarcoma is a rare entity. There are only a few reports in the literature that have focussed on its clinical behavior, histological features and treatment. Pure osteosarcoma needs to be distinguished from those arising in phylloides tumour or carcinosarcoma. It may arise from metaplastic sarcomatous transformation of neoplastic...

A 44 year old male presented with extensive hyperpigmentation and nodularity of skin of anterior chest wall and epigastrium .He was finally diagnosed as a case of POEMS syndrome. The clinical photograph of the skin is being sent for publication in the “Images” in the journal.

Metastases to the eye are rare and those from carcinoma esophagus are very rare, with only one report in the English literature. We report a 46-year-old man with adenocarcinoma of esophagus who developed isolated choroid metastasis after definitive treatment of the primary tumor.

Primary adrenal non-Hodgkin's lymphoma is very rare. We have seen 2 such cases among 241 cases of non-Hodgkin's lymphoma (0.83%) over the past 4 years. We could detect 2 more cases who had adrenal involvement, in addition to other extra nodal disease sites. Review of English literature revealed 65 cases of primary adrenal non-Hodgkin's lymphoma, mo...

The POEMS syndrome, also known as Crow-Fukase disease, is a rare multisystem disorder, which may take several years to evolve fully. The combination of symptoms and signs is highly complex and some of the features are detected at sub-clinical level requiring high level of suspicion. The clinical data on POEMS is still evolving with only a few case...

About one-third of NHL patients present lymphomas at extranodal sites. Involvement of multiple noncontiguous extranodal sites at presentation without lymph node involvement is unknown. Herein we present two such cases. The first patient had sinonasal tract and urinary bladder NHL at presentation, while the other patient presented with bilateral adr...

A 65year old male presented with obstructive voiding symptoms and recurrent hematuria following transurethral resection of malignant prostates. Following an unsuccessful attempt at catheterization, urethroscopy revealed narrowing of anterior urethra secondary to multiple nodular lesions. Biopsy of lesion showed adenocarcinoma positive for prostate...

A 65-year old male presented with obstructive voiding symptoms and recurrent hematuria following transurethral resection of malignant prostates. Following an unsuccessful attempt at catheterization, urethroscopy revealed narrowing of anterior urethra secondary to multiple nodular lesions. Biopsy of lesion showed adenocarcinoma positive for prostate...