Detlef Wegener

Detlef Wegener
Universität Bremen | Uni Bremen · Center of Cognitive Sciences

Dr. rer. nat.

About

43
Publications
8,414
Reads
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303
Citations
Additional affiliations
January 2004 - May 2021
Universität Bremen
Position
  • Permanent Faculty
Education
August 1994 - September 1995
University of Glasgow
Field of study
  • Life Sciences
October 1992 - October 1997
Universität Bremen
Field of study
  • Biology

Publications

Publications (43)
Article
Full-text available
Selective visual attention is known to be associated with characteristic modulations of neuronal activity in early visual cortex, but there is only rare evidence showing that these neuronal modulations are directly related to attention-dependent behavioral improvements. Here, we describe a strong, transient increase in the response of neurons in th...
Article
Full-text available
In human and nonhuman primates, goal-directed behavior requires the selection of relevant pieces of information from the multitude of simultaneous sensory inputs. Feature-based attention (FBA) plays a crucial role in this selection by improving the neuronal representation of an attended stimulus feature. Of particular interest for understanding the...
Article
Full-text available
Brain signal recordings with epidural microarrays constitute a low-invasive approach for recording distributed neuronal signals. Epidural field potentials (EFPs) may serve as a safe and highly beneficial signal source for a variety of research questions arising from both basic and applied neuroscience. A wider use of these signals, however, is cons...
Article
Full-text available
Sudden changes in visual scenes often indicate important events for behavior. For their quick and reliable detection, the brain must be capable to process these changes as independently as possible from its current activation state. In motion-selective area MT, neurons respond to instantaneous speed changes with pronounced transients, often far exc...
Article
Full-text available
Reaction times (RTs) are an essential metric used for understanding the link between brain and behaviour. As research is reaffirming the tight coupling between neuronal and behavioural RTs, thorough statistical modelling of RT data is thus essential to enrich current theories and motivate novel findings. A statistical distribution is proposed herei...
Article
Full-text available
The 5-choice serial reaction time task (5-CSRTT) is a behavioral test often used to study visuospatial attention and impulsiveness in rodents. The task requires animals to allocate attention to a horizontal array of five small apertures equipped with light sources and, within a limited time window, nose-poke one illuminated target aperture to get a...
Article
Full-text available
The non-human primate (NHP) constitutes an extraordinarily important model in neuroscience research for understanding the neuronal underpinnings of perceptual, motor, cognitive, and executive functions of the primate brain, and to study the physiological causes, effects, and potential treatments of brain disorders. Due to their cognitive capabiliti...
Preprint
Full-text available
Brain signal recordings with epidural microarrays constitute a low-invasive approach for recording distributed neuronal signals. Epidural field potentials (EFPs) may serve as a safe and highly beneficial signal source for a variety of research questions arising from both basic and applied neuroscience. A wider use of these signals, however, is cons...
Preprint
Full-text available
Sudden changes in visual scenes often indicate important events for behavior. For their quick and reliable detection, the brain must be capable to process these changes as independent as possible from its current activation state. In motion-selective area MT, neurons respond to instantaneous speed changes with pronounced transients, often far excee...
Article
Recordings of epidural field potentials (EFPs) allow to acquire neuronal activity over a large region of cortical tissue with minimal invasiveness. Because electrodes are placed on top of the dura and do not enter the neuronal tissue, EFPs offer intriguing options for both clinical and basic science research. On the other hand, EFPs represent the i...
Preprint
Full-text available
Recordings of epidural field potentials (EFPs) allow to acquire neuronal activity over a large region of cortical tissue with minimal invasiveness. Because electrodes are placed on top of the dura and do not enter the neuronal tissue, EFPs offer intriguing options for both clinical and basic science research. On the other hand, EFPs represent the i...
Article
Full-text available
Neurophysiological data acquisition using multi-electrode arrays and/or (semi-) chronic recordings frequently has to deal with low signal-to-noise ratio (SNR) of neuronal responses and potential failure of detecting evoked responses within random background fluctuations. Conventional methods to extract action potentials (spikes) from background noi...
Article
Non-human primates constitute an indispensable model system for studying higher brain func-tions at the neurophysiological level. Studies involving these animals elucidated the neuronal mechanisms of various cognitive and executive functions, such as visual attention, working memory, and decision-making. Positive Reinforcement Training (PRT) consti...
Preprint
Full-text available
Non-human primates constitute an indispensable model system for studying higher brain functions at the neurophysiological level. They can be trained on highly demanding cognitive tasks, and studies involving these animals elucidated the neuronal mechanisms of various cognitive and executive functions, such as visual attention, working memory, and d...
Article
Full-text available
University of Bremen neuroscientists Andreas Kreiter and Detlef Wegener argue on the importance of non-human primate studies for basic and translational biomedical research in Europe.
Article
Full-text available
Neuroscientist Dr Detlef Wegener and his colleagues at the University of Bremen’s Brain Research Institute in Germany study how cognitive processes influence the way we perceive the world in which we live and act.
Presentation
Full-text available
Presentation on "25th Annual Computational Neuroscience Meeting: CNS-2016 " BMC Neuroscience 17, 112-113 (2016).
Preprint
Full-text available
Non-spatial selective attention is based on the notion that specific features or objects in the visual environment are effectively prioritized in cortical visual processing. Feature-based attention (FBA) in particular, is a well-studied process that dynamically and selectively enhances neurons preferentially processing the attended feature attribut...
Conference Paper
Full-text available
ICGenealogy: towards a common topology of neuronal ion channel function and genealogy in model and experiment Ion channels are fundamental constituents determining the function of single neurons and neuronal circuits. To understand their complex interactions, the field of computational modeling has proven essential: since its emergence, thousands...
Article
Full-text available
Neurons in the middle temporal area (MT) respond to motion onsets and speed changes with a transient-sustained firing pattern. The latency of the transient response has recently been shown to correlate with reaction time in a speed-change detection task, but it is not known how the sign, the amplitude, and the latency of this response depend on the...
Article
Full-text available
Directing attention to a specific feature of an object has been linked to different forms of attentional modulation. Object-based attention theory founds on the finding that even task-irrelevant features at the selected object are subject to attentional modulation, while feature-based attention theory proposes a global processing benefit for the se...
Article
Full-text available
Perception of constant motion has been extensively studied both psychophysically and physiologically, but the human ability to detect dynamic changes in motion, such as rapid speed changes, is only poorly characterized and understood. Yet, perception and representation of such dynamic changes is of strong behavioral relevance, as illustrated by the...
Article
Full-text available
In monkeys, long-term recordings with chronically implanted microelectrodes frequently suffer from a continuously decreasing probability to record single units or even small multiunit clusters. This problem is associated with two technical limitations of the available devices: first, restrictions for electrode movement, and second, absent possibili...
Article
Full-text available
Feature-directed attention has been recently studied in various psychophysical, electrophysiological, and imaging studies. Convincing evidence has been obtained for its global effectiveness, but there is a debate about the processing fate of non-attended target features. A number of studies demonstrated feature-directed attention being associated w...
Article
Full-text available
We report findings from several variants of a psychophysical experiment using an acceleration detection task in which we tested predictions derived from recent neurophysiological data obtained from monkey area MT. The task was designed as a Posner paradigm and required subjects to detect the speed-up of a moving bar, cued with 75% validity. Display...
Article
Full-text available
Remarkable alterations of perception during long-lasting attentional processes have been described in several recent studies. Although these findings have gained much interest, almost nothing is known about the modulation of neuronal responses during sustained attention. Therefore, we investigated the effect of prolonged selective attention on neur...
Thesis
Eine zentrales Interesse der modernen Neurowissenschaft besteht darin, kognitive Prozesse wie Aufmerksamkeits- oder Gedächtnisleistungen auf Ebene einzelner Neurone zu verstehen. Die in diesem Buch beschriebene Studie tritt den Nachweis an, dass selektive visuelle Aufmerksamkeit die neuronale Repräsentation von Objekten bereits auf Ebene der frühen...
Conference Paper
In plethodontid salamanders retinal ganglion cells (rgc) terminate in the superficial three layers of the optic tectum and the basal optic nucleus (BON)[1]. On the basis of HRP and Golgi studies, four mor-phologically distinct types of rgc have been previously described, including small, medium-sized and large rgc. Medium-sized rgc were further sub...

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Projects

Projects (3)
Project
Understanding behavioral and neuronal dynamics and top-down modulation of change detection
Project
Investigating behavioral and neuronal conditions causing object- or feature-dominated processing of visual information