Denis o'Leary

Denis o'Leary
University of Oxford | OX · Division of Medical Sciences

About

32
Publications
2,880
Reads
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1,183
Citations
Citations since 2016
7 Research Items
273 Citations
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20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060

Publications

Publications (32)
Article
Full-text available
Introduction: The complexity of new terms for UK trainee doctors has raised concerns for patient safety and team working. Older terms (junior or resident) may compound these effects. This study explores other team-members’: (i) understanding of the new terminology; (ii) accuracy of matching clinical tasks to the core training grade; and (iii) attit...
Conference Paper
Background: Ten years ago, concerns were raised that quality of postgraduate training would be compromised by socially, economically, and politically driven changes in the UK; which might have contributed to the current recruitment and retention crisis. We aimed to test these concerns through a survey of trainees’ experience. Methods: A cross-secti...
Article
Full-text available
Traditionally, two divergent approaches are used to explain the mechanism of action of psychotropic drugs. The dominant “Disease-centred” view emphasises the biochemical imbalance caused by ‘illnesses’. In contrast the “Drug-centred” view emphasises the psychoactive properties of these drugs and their ability to induce an ‘altered-state’ of mind. I...
Article
Full-text available
A recent Royal College of Physicians' study on assessment raises serious questions for workplace assessment. To address these, a system is recommended that bridges the gap from competence to performance and integrates supervised learning events (SLEs) that are formative in purpose with summative assessment of performance by entrustable professional...
Article
The safety of trainees is a key concern within any psychiatric training scheme. The Royal College of Psychiatrists has suggested respective national standards.AimTo audit compliance with standards related to the safety of psychiatric trainees within a Mental Health Trust in the United Kingdom.Method All trainees working within the Mental Health Tru...
Article
The aim of this audit was to identify the performance of the Bicester component of the North Oxfordshire Community Mental health team across a selected number of patient satisfaction questions that are related to patient awareness of CPA.Methodology:The domain for audit included the following items:1.Knowledge of the care coordinator2.Accessibility...
Article
Full-text available
Aims and method Relative to workforce numbers, the National Clinical Assessment Service (NCAS) has reported high rates of referrals for performance concerns in psychiatrists. Our aim was to see how these concerns would be distributed across good medical practice (GMP) domains. Such specification would help identify appropriate training and developm...
Article
This paper extends previous work describing course in depression using a recommended operational model that defines remission onset and relapse. We test whether a similar course pattern would emerge using this model in a new cohort of depressed participants. We recruited a cohort of 86 participants, first-time inpatients, with DSM-IV major depressi...
Article
Full-text available
Background Lithium carbonate and valproate semisodium are both recommended as monotherapy for prevention of relapse in bipolar disorder, but are not individually fully effective in many patients. If combination therapy with both agents is better than monotherapy, many relapses and consequent disability could be avoided. We aimed to establish whethe...
Article
We reviewed suicide rates in affective disorder and their variation with electroconvulsive therapy (ECT) and antidepressant availability. Suicide rates were calculated from 75 follow-up studies, identified by systematic literature searches and analyzed for differences over time eras characterized by the availability of specific treatments. MEDLINE,...
Article
The relationship between personality and depressive illness is complex. The aim of this study was to assess whether the presence of a personality disorder or high neuroticism (N) scores predicted longer times to discharge or remission onset or higher risks of relapse for a cohort of depressed subjects admitted for the first time. 100 consecutive su...
Article
Background: Few prospective studies of course for first admission depressives are reported. Methods: One hundred consecutive depressed inpatients were followed prospectively over 18 months. Course was defined operationally using the Hamilton Depression scale and ICD-10 criteria. Results were analysed using life-tables. Results: The cumulative proba...
Article
Few prospective studies of course for first admission depressives are reported. One hundred consecutive depressed inpatients were followed prospectively over 18 months. Course was defined operationally using the Hamilton Depression scale and ICD-10 criteria. Results were analysed using life-tables. The cumulative probabilities of remission onset by...
Article
This study aimed to replicate findings that length of episode prior to adequate antidepressant treatment (the 'no-treatment interval') and premorbid neuroticism predict time to remission from the institution of adequate treatment for depression. Eighty-three inpatients meeting ICD-10 criteria for a depressive illness were entered into an 18-month p...
Article
This paper examines the interval between the onset of depressive illness and subsequent medical presentation in a group of patients undergoing their first psychiatric admission with moderate to severe depression. The average preconsultation interval was 76 days, compared with an average time from consultation to the commencement of adequate treatme...
Article
Patients with unipolar depression show impaired performance on the Tower of London planning task. Positron emission tomography, which has previously identified resting state blood flow abnormalities in depression, was used to investigate neural activity associated with performance of this task in depressed patients and normal controls. Six patients...
Article
The naturalistic course of patients with endogenous subtype of depression is described. The subtype may predict shorter times to remission, and reduced relapse risk. In the longer term, the subtype predicts increased risk of readmission, though studies on recurrence are equivocal. Recurrence of endogenous episodes may be less dependent on life even...
Article
The longer term prognosis of depressed patients treated with ECT is relatively unknown. We describe seven-year mortality and readmission risks for the Nottingham ECT series. Cases were defined and subtyped using the Present State Examination (PSE). Follow-up was naturalistic. Death and readmission were ascertained using the Nottingham case register...
Article
Full-text available
This report describes the use of the needs for care assessment (NFCA) in measuring symptom and social function in patients with long-term mental illness. The schedule recommends specific care interventions and these were implemented where appropriate. The problem status at the patients was reassessed using the needs for care schedule after the inte...
Article
The Nottingham electroconvulsive therapy (ECT) trial was designed with a simulated treatment group to test prospectively the power of delusions or agitation to predict response. The response of patients without retardation and without delusions was examined retrospectively as well because of doubts over the usefulness of ECT for this subgroup. Delu...
Article
The results of the Nottingham electroconvulsive therapy (ECT) trial were examined to compare the response of patients aged 60 and over to real versus simulated ECT. The outcome of patients given real compared to simulated ECT was significantly better immediately after six study treatments. Unilateral ECT was an effective as bilateral treatment. The...

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