Demba Diedhiou

• MD, PhD
• Cheikh Anta Diop University

: The dermatological manifestations of Graves' disease exhibit a polymorphic nature. Our objective was to delineate the diverse cutaneous, mucosal, and pharyngeal manifestations associated with Graves' disease and to assess the influence of the received treatments. : This cross-sectional study involved the prospective collection of data conducted b...

Introduction: Dietary practices can lead to stunted growth in children. The aim was to study stunting and dietary practices in children under 5 in the Sedhiou region. Methodology: This was a descriptive and analytical cross-sectional study. The target population was children under 5 years of age. The sampling method was two-stage cluster sampling....

Background: Early detection of arterial damage is essential for the primary prevention of complications linked to type 2 diabetes (T2D). The study assessed the cardiovascular risk of sub-Saharan African individuals with T2D, while exploring possible mechanisms involved in the pathogenesis of vascular complications in this population. Methodology: A...

Introduction: Hypothyroidism can lead to lipid abnormalities. Work on this entity remains limited in Africa. The aim was to describe the characteristics of dyslipidemia in hypothyroid patients at the Clinique Médicale II of the Centre Hospitalier Abass Ndao in Dakar. Patients and methods: This was a cross-sectional, descriptive and analytical study...

Introduction: Diabetes is a public health problem, exposing patients to serious complications including ketoacidosis. The aim of this study was to describe the epidemiological, therapeutic and evolutionary aspects of diabetic ketoacidosis at the Abass ndao hospital in Dakar. Patients and Methods: This was a cross-sectional, descriptive study conduc...

Epidemiological data predicts that Sub-Saharan Africa will have the largest increase in type 2 diabetes (T2D) prevalence over the next two decades. Metabolomics studies have identified biomarkers that could improve T2D diagnosis and follow-up. However, no studies have characterized the metabolome of people from Sub-Saharan Africa. Plasma samples fr...

Introduction Les polyendocrinopathies auto-immunes (PEAI) sont des maladies caractérisées par la coexistence d’au moins deux affections endocrines de mécanisme auto-immun, associées parfois à une affection auto-immune non endocrinienne. Elles représentent un groupe de pathologies concomitantes, de fréquence rare, présentant une hétérogénéité cliniq...

The association between hyperuricemia and metabolic syndrome (MS) has been reported in many studies. The authors performed this cross-sectional study to determine the association between hyperuricemia and the MS among diabetic patients in Dakar. Type 2 diabetic patients received as part of their follow-up at the Marc Sankalé Center of Abass Ndao Ho...

Thyroid abscess is a very rare disease due to its anatomical position and the physiology of the gland. It most often occurs in the immunosuppressed population. The diagnosis is easy and is based on ultrasound. However it is often unrecognised. Bacteriological examination allows to identify the germ responsible for this condition. We report the case...

Introduction: This study aims to determine the clinical and evolutionary profile of skin and soft tissue lesions in diabetics followed up at the dressing room. Methods: We conducted an observational descriptive and analytical study in the dressing room of the Marc Sankalé Diabetes Center, Dakar from 1 January to 31 December 2017. Our study focus...

Pyoderma gangrenosum (PG) is a rare non-infectious neutrophilic dermatosis often unknowed. It usually presents with inflammatory skin ulcer, very painful, with rapid evolution. It is commonly found in a context of malignancy, inflammatory bowel disease, rheumatic and/or haematological disease. Its diagnosis is very often late after multiple therape...

Fasting glucose (FG) and glycated hemoglobin A1c (HbA1c) perform sub-optimally in people of African origin, especially in individuals with sickle-cell trait (SCT). The purpose of this study was to compare the relationships between HbA1c, FG, and fructosamine in individuals from Senegal with and without SCT. HbA1c, FG, and fructosamine were measured...

Objective: The prevalence of type 2 diabetes (T2D) is rapidly increasing in Sub-Saharan Africa, where sickle-cell trait (SCT) is also frequent. Although SCT is generally considered a benign condition, evidence suggests that SCT could exaggerate vascular dysfunction in T2D. However, it remains unclear whether SCT could increase the risk of developin...

Introduction Graves’ disease remains the most frequent cause of hyperthyroidism but poorly described in men. The objective was to study the specificities of Graves’ disease in this population at Abass Ndao University Hospital Center in Dakar (Senegal). Patients and methods It was a descriptive and analytical retrospective study conducted over 20 ye...

Introduction: Systemic scleroderma is a chronic inflammatory disease with cardiovascular complications that make it is a serious condition. There would be a body modification during autoimmune, systemic and chronic inflammatory states. These changes would be responsible for one part of the cardiovascular morbidity and mortality of the disease. It i...

Introduction L'hyperthyroïdie de l'enfant semble rare et constitue un problème de par son retentissement psychosomatique. L’objectif était de faire le point sur ses aspects épidémiologiques et diagnostiques chez l’enfant à Dakar. Méthodes Il s'agissait d'une étude multicentrique, descriptive sur 15 ans. Etaient analysés les aspects épidémiologique...

Introduction: L'hyperthyroïdie de l'enfant semble rare et constitue un problème de par son retentissement psychosomatique. L'objectif était de faire le point sur ses aspects épidémiologiques et diagnostiques chez l'enfant à Dakar. Méthodes: Il s'agissait d'une étude multicentrique, descriptive sur 15 ans. Etaient analysés les aspects épidémiologiqu...

Introduction: The association of diabetes and pregnancy represents a potential risk for both the mother and the fetus. The objective was to assess the morbidity and mortality of newborns of diabetic mothers and to identify maternal and neonatal risk factors. Materials and methods: This was a retrospective, descriptive and analytical study carried o...

Rheumatoid arthritis is often characterized by fatal cardiovascular events. Endothelial dysfunction would be a predictive marker of the occurrence of such cardiovascular events. Impaired endothelial function is often the initial stage of vascular pathology in rheumatoid arthritis. Thus the aim of our study was to assess endothelial function in blac...

Introduction: The diagnosis of cardiothyreosis is based on the presence of the association of thyrotoxicosis and various cardiovascular disorders such as heart failure, coronary artery disease, rhythm or conduction disorders. Data are limited on this entity in Africa which a frequency of 10% to 33% among hyperthyroidism. We aimed to evaluate these...

Background: Rheumatoid arthritis is a systemic disease with often fatal vascular events. In addition to traditional cardiovascular risk factors, disease-specific elements contribute to this cardiovascular mortality. The aim of this study was to assess arterial stiffness in rheumatoid arthritis and to determine the factors involved. Methods: We have...

Résumé Les infections de la main chez le diabétique, décrites sous le nom de « Syndrome de la main diabétique tropicale », sont moins courantes que les atteintes du pied, mais exposent également à des conséquences invalidantes majeures. L’objectif de notre étude était de déterminer leurs caractéristiques épidémiologiques, cliniques, étiologiques et...

Abstract: During a period of three (3) years, from January 2011 to December 2013, we conducted a cohort study of a population of 981 women hospitalized for complications during pregnancy (GP) for risk of premature delivery or abortion to assess the prevalence of Escherichia coli and specific pathogenic bacteria (SPB), namely Mycoplasma and Chlamydi...

Abstract: This retrospective study reproduces the correlation between glycated hemoglobin and fasting glucose in diabetic patients black Abass Ndao Hospital from 1 January 2010 to 31 December 2011 identifying the data on the register of biochemistry laboratory. We proposed glycemic intervals starting from the lowest value with increases of 0.2 g/l...

Objectives: To assess the clinical particularities and management of Graves’ disease at the Medical Clinic II of the Abass Ndao Hospital Centre in Dakar. Patients and methods: This was a retrospective, descriptive study on records of patients monitored for Graves' disease from 1 January 2010 to 31 December 2014 (5 years). Socio-demographic, clinica...

The aim of our study was to determine epidemiological, clinical and therapeutic profile of colorectal cancers in Mauritania. Patients and Methods: It was a retrospective multicentric study conducted over 5 years in Nouakchott National Hospital Centre and in private clinics of Mauritania. All cases of colorectal cancers histologically confirmed were...

Denosumab is an anti-RANK ligand (RANKL) monoclonal antibody approved for the treatment of postmenopausal osteoporosis and prevention of skeletal metastasis complications. Administered subcutaneously every 6months, it reduces the risk of vertebral fracture by 70% and of hip fracture by 40%. Its safety profile is acceptable. Denosumab may be used to...

Résumé L’Afrique sub-saharienne, caractérisée par la pauvreté, les maladies transmissibles, l’insuffisance des infrastructures et du personnel de santé, doit faire face au fardeau du diabète sucré. Bien que les données soient insuffisantes, la prévalence et le nombre de cas, estimés respectivement à 4,8 % et 19,1 millions, seront respectivement de...

Introduction La chirurgie bariatrique est une réponse à l’épidémie mondiale d’obésité de l’adulte. Le court-circuit gastrique représente la majorité des interventions dans le monde. Il provoque des bouleversements métaboliques aigus qui affectent l’équilibre osseux. Cette revue est consacrée aux conséquences osseuses du court-circuit gastrique. Ma...

Diabetic neuropathy occurs in more than 60% of diabetic’s populations. The aim of our study wasto describe clinical and electromyography characteristics of diabetic neuropathy in a Senegalese black diabetic population (Senegal). This was a cross-sectional study of 68 neuropathic type 2 diabetic patients with 56.8years mean age. Clinical examination...

Introduction: The objective of this study was to investigate the determinants of rape among minors in the Kolda region. Methodology: A retrospective, cross-sectional, descriptive and analytical was conducted from 23 December 1992 to 31 December 2011, based on the charts of rape victims under the age of 18 years. Sampling was complete. Bivariate...

Study of determinants of rape in minors in the Kolda region of Senegal Introduction: The objective of this study was to investigate the determinants of rape among minors in the Kolda region. Methodology: A retrospective, cross-sectional, descriptive and analytical was conducted from 23 December 1992 to 31 December 2011, based on the charts of rape...

Sexual steroids are major determinants of skeletal maturation and steady state. Estrogens are mandatory in both sexes. They induce endochondral bone formation and growth plate knitting. Androgens are mainly active in male. They increase length and radial bone growth. These differences explain the duality of biomechanics in both sexes. Deep androgen...

Introduction Lack of specialists is one of the major problems in the management of diabetes mellitus in sub-Saharan Africa. Our objective was to evaluate the practice of trained general practitioners (GPs) on diabetes. Material and methods A multicenter study was conducted in Senegal and Côte-d’Ivoire from August 2008 to August 2009. Untreated typ...

Introduction: There are three forms of bacterial dermohypodermitis according depth of lesion and lowers limbs prevail. Objective was to estimate epidemiological, clinical and progressive aspects of bacterial dermohypodermitis in internal medicine in Dakar. Patients and method: A retrospective study over 5 years was carried out to analyze aspects of...

Introduction : Peu d’études ont été consacrées à la thrombophlébite des membres inférieurs sur diabète sucré. Le but était d’étudier les aspects épidémiologiques, cliniques et étiologiques de la phlébite des membres inférieurs chez les sujets diabétiques en comparaison de patients non diabétiques. Patients et méthodes : il s’agissait d’une étude tr...

Summary Introduction: Diabetic foot ulcers represent a significant cause of morbidity. The major risk is amputation. The purpose of this study was to look at the epidemiological, clinical, and evolutionary aspects of foot ulcers as well as the main etiologies and those most prone to amputation in diabetic subjects in Dakar. Patients and method: It...

The main goal of this study was to describe the use of therapeutic resources available for diabetes management in Senegal. There were 387 patients, enrolled in this study from 5 medical centers for diabetes care. Type 2 diabetes represented 92.5% and 7.2% were type 1. Mean age was 52.2 ± 12.4 years and mean HbA1c 7.6 ± 2.4%. Among type 2 patients,...

Introduction : Seul ou associé à d’autres facteurs de risque vasculaire, le diabète est responsable d’une lourde morbi-mortalité partout dans le monde. Son expansion prend des allures de pandémie, mais elle reste encore peu documentée en Afrique sub-saharienne. Ce travail fournit quelques aspects épidémiologiques du diabète parmi les autres facteur...