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27
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Introduction
Current institution
Additional affiliations
December 2022 - present
Education
September 2007 - September 2013
Faculty of Medicine
Field of study
- Medicine
Publications
Publications (27)
Numerous studies reported about potential effects of L-carnosine in regulation of tumor growth and metabolism. We evaluated the effects of different concentrations of L-carnosine from Karnozin EXTRA® supplement on mitochondrial respiratory chain complexes of human embryo lung fibroblasts (MRC-5) and human breast cancer cells (MCF-7), with different...
Background and Objective
Nowadays, the separation of adenocarcinomas (ADCs) and squamous cell carcinomas (SCCs) is crucial given that there are new specific targeted therapies. So, the aim of this study was to examine the differences in cytomorphological features between ADC and SCC in bronchoscopic brush samples.
Material and Methods
The retrospe...
Introduction: Primary pulmonary sarcomas (PPS) are a diverse group of rare non-epithelial malignant lung tumors, accounting for about 5% of all malignant lung tumors, originating from mesenchymal tissue. Although we are living in an era of great progress in molecular diagnostics, which has contributed to a more accurate diagnosis and classification...
Introduction: Fungal infections are becoming a major public health problem in an era of global increase in the number of immunocompromised patients. Radiological manifestations of this disease include a wide range of differential diagnoses, including malignant diseases. Case report: We present the case of a patient who underwent for surgical treatm...
The aim was to detect and correlate anticancer effects of metformin in combinations with other repurposed drugs, already registered for other indications, which may be immediately applied and clinically investigated in oncology, reducing the time and cost of research for new cancer treatments. Immunohistochemistry was performed for tumors treated b...
(1) Background: home-based spirometry, as a form of telemedicine in pulmonology, was previously successfully implemented in clinical practice in developed countries. However, experiences from developing countries are lacking. The aim of this study was to assess the reliability and feasibility of home-based spirometry in patients with interstitial l...
Introduction: According to the ATC system of drug classification, group R06 includes H1 antihistamines for systemic use, which are divided into drug groups of the 1st and 2nd generation. Aim: Since there are no national guidelines in Serbia, for treating most allergic diseases, our aim was to compare pharmaceutical products and treatment strategies...
Objective:
The objectives of our study were to examine the adequacy of samples and accuracy of transthoracic needle aspiration (TTNA) in patients with peripheral pulmonary nodule (PPN) diagnosis.
Methods:
The retrospective study included 248 patients who underwent TTNA of PPN and subsequent diagnostic-therapeutic surgical procedure during a 5-ye...
Background and Objectives: The COVID-19 pandemic has led to significant changes globally , which has also affected patients with type 1 diabetes mellitus (T1DM). This study aimed to determine the incidence of T1DM and the characteristics of diabetic ketoacidosis (DKA) during the pandemic comparing it to pre-pandemic period. Materials and Methods: D...
MILJKOVIC, D.; DRLJACA, J.; LOVRENSKI, A. & GAJIC, M. A comprehensive morphometric study of visceral and subcutaneous adipose tissue depots in mice, hamsters and rats. SUMMARY: Adipose tissue morphology of different fat tissue depots can be described using the number of adipocytes and cell surface of adipocytes. This study deals with characteristic...
The paper presents a pathological-radiological correlation of the manifestation of mucosal cystadenoma with ovarian stroma of the liver with examination and correlation with the new stroma nomenclature and differential diagnostic dilemmas of radiologists and pathologists.
Carnosine is known as a natural dipeptide, which inhibits the proliferation of tumor cells throughout its action on mitochondrial respiration and cell glycolysis. However, not much is known about its effects on the metabolism of healthy cells. We explored the effects of Karnozin EXTRA® capsule with different concentrations of L-carnosine, on the ce...
We investigated the anticancer effect of disulfiram and metformin combination on fibrosarcoma in hamsters. Hamsters of both sexes (~ 70 g) were randomly allocated to control and experimental groups (8 animals per group). In all 10 groups, 2 × 106 BHK-21/C13 cells in 1 ml were injected subcutaneously into the animals' backs. Peroral treatments were...
The aim of the present study was to evaluate the effect of different staining techniques on applicability and accuracy of tooth cementum annulation (TCA) method. Nine decalcination techniques, 8 dehydration protocols and 8 different techniques were applied in 3 teeth from the persons of a known age. Black and white, and color images of histological...
We investigated the effect of nitroglycerin with metformin on fibrosarcoma in hamsters. Syrian golden hamsters of both sexes, weighing approximately 60 g, were randomly allocated to control and experimental groups, with 8 animals per group. In all groups, 2 × 10⁶ BHK-21/C13 cells in 1 ml were injected subcutaneously into the animals’ backs. Peroral...
Aim:
A growing body of evidence pointed correlation between insulin-resistance, testosterone level and infertility, but there is scarce information about mechanisms. The aim of this study was to identify the possible mechanism linking the insulin-resistance with testosterone-producing-Leydig-cells functionality.
Methods:
We applied in vivo and i...
The thymus is the primary lymphoid organ involved in the regulation of the immune and endocrine systems. It is particularly sensitive to various types of stress, which induce its atrophy. This study deals with the effect of repeated restraint stress on the weight, proliferation and apoptosis of the thymus in mice. During restraint, the animals were...
The anticancer effects of metformin (an antihyperglycaemic agent) and itraconazole (an antifungal agent), which are established non-oncologic drugs, were investigated in the present study. The weight, diameter, volume, density, surface, surface to volume ratio and immunohistochemistry of experimental fibrosarcoma tumors were investigated in hamster...
Pycnogenol® (PYC) has already being used as a food supplement and herbal medicine due to its potent antioxidant properties. The aim of the present study was to examine the protective effect of PYC on acetaminophen‐induced acute liver injury in rats. The effect of PYC on acetaminophen‐induced hepatotoxicity in rats was examined by determining bioche...
Controlled changes in mitochondrial biogenesis and morphology are required for cell survival and homeostasis, but the molecular mechanisms are largely unknown. Here, male and female prepubertal mice (P21) with insulin and IGF1 receptors deletions in steroidogenic tissues (Insr/Igf1r-DKO) were used to investigate transcription of the key regulators...
Objective:
We investigated the effect of metformin and caffeine on fibrosarcoma in hamsters.
Materials and methods:
32 Syrian golden hamsters of both sexes, weighing approximately 100 g, were randomly allocated to 3 experimental and 2 control groups, with a minimum of 6 animals per group. 2 x 106 BHK-21/C13 cells in 1 ml were injected subcutaneo...
Objective:
We investigated the effect of metformin on an in vivo solid tumor model of fibrosarcoma in hamsters.
Materials and methods:
33 Syrian golden hamsters of both sexes, weighing approximately 100 g, were randomly allocated to 3 experimental and 2 control groups. 2 x 106 BHK-21/C13 cells in 1 ml were injected subcutaneously into the animal...
Purpose: To investigate the effect of mebendazole on an in vivo solid tumor model of fibrosarcoma in hamsters. Methods: 24 Syrian golden hamsters of both sexes with the approximate body weight of 100g were randomly distributed in 2 experimental and 2 control groups, with 6 animals in each group. BHK-21/C13 cells (2 x 10⁶) in 1 mL Glasgow Minimum Es...
Both histology and pathology as a scientific fields and as an educational subjects have always relied on technology. In the 19th century a major breakthrough happened in certain areas related to histotechnology, so histology and pathology were rapidly developing. Technological revolution has lead to modernization of histology and pathology teaching...
