Deborah J Gaebler-Spira

Deborah J Gaebler-Spira
Northwestern University | NU · Feinberg School of Medicine

About

43
Publications
6,005
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
926
Citations

Publications

Publications (43)
Article
Full-text available
Importance: Early identification of cerebral palsy (CP) is important for early intervention, yet expert-based assessments do not permit widespread use, and conventional machine learning alternatives lack validity. Objective: To develop and assess the external validity of a novel deep learning-based method to predict CP based on videos of infants...
Article
Peer review is an important process that produces the evidence-based medicine that guides the standards by which we provide care. We all have a role to contribute to the advancement of our field through involvement in this process. Opportunities and guidance to the next generation of reviewers is essential to continue to move our field forward and...
Article
This qualitative study evaluated barriers and facilitators to mobility in the homes of children with medical complexity (CMC) and the subsequent impact on CMC and their families. Eighteen caregivers of CMC were interviewed. Parents described that accessibility barriers impaired delivery of care at home and impacted the child’s participation in fami...
Article
Aim: To understand the mobility experiences, supportive mobility device (SMD) use, and desired participation outcomes of individuals with cerebral palsy (CP) across the life span, and describe how perspectives of rehabilitation care and professional resources may influence mobility decision-making processes and outcomes. Method: In the second ph...
Article
Full-text available
Children and adolescents with movement challenges have lower instances of physical activity and longer time spent in sedentary behaviors compared to children with typical development. The purpose of this study was to investigate the feasibility of a sport-based youth development running program modified for accessibility using a running frame and t...
Article
Introduction: Adults with cerebral palsy (CP) face high morbidity from cardiovascular disease (CVD). Concerningly, classic screening parameters are inconsistent in identifying CVD risk in this population. Dual Energy X-ray absorptiometry (DEXA), which provides direct measurements of fat mass (FM), may be an alternative screening method. Objective:...
Article
Objective: To describe the relationship between activity level and cardiovascular risk measures as well as describe general activity patterns of adults with cerebral palsy Design: Cross‐Sectional Setting: Academic Outpatient Rehabilitation Clinic. Participants: 47 adults with cerebral palsy (CP) Interventions: Not applicable Main Outcome Measures:...
Article
Greater ventriculomegaly in preterm infants with intraventricular hemorrhage (IVH) has been associated with worse neurodevelopmental outcomes in infancy. We aim to explore the relationship between ventriculomegaly and school-age functional outcome. Retrospective review of preterm infants with Grade III/IV IVH from 2006 to 2020. Frontal–occipital ho...
Article
Aim To determine whether functional impairments and autonomic symptoms are correlated in young people with developmental and epileptic encephalopathies (DEEs). Method Cross-sectional, online surveys (2018–2020) of parents recruited from family groups obtained information on several aspects of children’s conditions including functional abilities (m...
Article
Background: All women, regardless of disability status, should receive screening for breast cancer. In 2010, only 61.4% of women with disabilities (WWD) received a mammogram in the past 2 years compared to 75% of women without disabilities. The purpose of this study is to explore breast cancer screening experiences of women with cerebral palsy (CP)...
Article
Aim: To assess diet quality and its relationship with cardiovascular health measures for adults with cerebral palsy (CP). Method: A convenience sample of 45 adults with CP (26 females, 19 males; mean age 35y 10mo [SD 14y 9mo]). were recruited for this cross-sectional study. Demographic, medical, and Gross Motor Function Classification System (GM...
Article
Full-text available
In this study we investigate the disease etiology in 12 patients with de novo variants in FAR1 all resulting in an amino acid change at position 480 (p.Arg480Cys/His/Leu). Following next-generation sequencing and clinical phenotyping, functional characterization was performed in patients’ fibroblasts using FAR1 enzyme analysis, FAR1 immunoblotting/...
Article
Rationale Developmental epilepsies and encephalopathies (DEEs) are characterized by many severe developmental impairments, which are not well-described. A functional framework could facilitate understanding of their nature and severity and guide the selection instruments to measure improvements in therapeutic trials. Methods An online survey admin...
Conference Paper
Despite growing evidence focused on early power mobility, questions regarding application in practice persist and may influence a young child’s access to power mobility. This full day workshop explores advantages and barriers for clinical and community implementation of power mobility programs for infants and toddlers with mobility limitations. Evi...
Article
Full-text available
Background: Early identification of cerebral palsy (CP) during infancy will provide opportunities for early therapies and treatments. The aim of the present study was to present a novel machine-learning model, the Computer-based Infant Movement Assessment (CIMA) model, for clinically feasible early CP prediction based on infant video recordings....
Article
Smaller, smarter, more portable rehabilitation technology has the potential to improve the ability of individuals with cerebral palsy to perform activities and increase participation. Robotics and virtual reality may improve movement by maximizing exercise dose, providing feedback, and motivating users. Augmentative and alternative communication te...
Article
Full-text available
Background: Early prediction of cerebral palsy (CP) using the General Movement Assessment (GMA) during the fidgety movements (FM) period has been recommended as standard of care in high-risk infants. The aim of this study was to determine the accuracy of GMA, alone or in combination with neonatal imaging, in predicting cerebral palsy (CP). Method...
Article
Although various treatment methods have been investigated to reduce spasticity and intoeing gait in children with cerebral palsy (CP), methods to concurrently reduce an intoeing gait and associated ankle/knee stiffness and spasticity according to a child's specific needs are lacking. This study aimed to develop a training program to improve walking...
Article
Aim To conduct a review of research literature on the use of dance and movement with music (rhythmic auditory stimulation [RAS]) in the neurorehabilitation of children and adults with cerebral palsy (CP). Method We conducted a systematic search and quality appraisal of the research literature on dance and RAS in CP. Additionally, we linked the res...
Article
Full-text available
Objective: To evaluate the feasibility and effectiveness of a wearable robotic device in guiding isometric torque generation and passive-active movement training for ankle motor recovery in children with acute brain injury. Participants/setting: Ten inpatient children with acute brain injury being treated in a rehabilitation hospital. Design:...
Article
To assess the prevalence, type, and impact of urinary problems in adults with cerebral palsy (CP) and their relationship with Gross Motor Functional Classification Scale (GMFCS). Cross-Sectional Prospective Survey Study SETTING: Outpatient, Urban, Academic Rehabilitation Clinic PARTICIPANTS: 91 adults with cerebral palsy (45 women and 46 men) INTER...
Article
Full-text available
The aim of this systematic review was to inform evidence-based clinical practice guidelines for children with cerebral palsy (CP) and low bone mineral density (BMD). A computer-assisted literature search was focused on low BMD in children with CP, and was limited to the following interventions: weight-bearing activities, bisphosphonate use, and vit...
Article
To evaluate spasticity under controlled velocities and torques in children with cerebral palsy (CP) using a manual spasticity evaluator. The study involved 10 children with spastic CP (six males, four females; mean age 10 y 1 mo, SD 2 y 9 mo, range 7-16 y; one with quadriplegia, six with right hemiplegia, three with left hemiplegia; Gross Motor Fun...
Article
Full-text available
Aim The aim of this systematic review was to examine the literature on the effects of partial body-weight support treadmill training (PBWSTT) in children with cerebral palsy (CP) on functional outcomes and attainment of ambulation. Method We searched the relevant literature from 1950 to July 2007. We found eight studies on the use of PWSBTT on func...
Article
Full-text available
Fourteen participants (six females, eight males) ranging in age from 7 years 11 months to 18 years 2 months (mean 11y 7mo) with a confirmed diagnosis of spastic cerebral palsy (CP) were included in the study. Participants included those who drooled (CP+, n=14); age- and sex-matched children with spastic CP who were dry to mild and never to infreque...
Article
The aim of this study was to examine measures of health-related quality of life (HRQL) in children with cerebral palsy (CP) by comparing scores of a generic HRQL measure, the Child Health Questionnaire (CHQ); a disease-specific HRQL measure for children with CP, the Caregiver Questionnaire (CQ); and a pediatric functional measure, the Wee-Functiona...
Article
Full-text available
electrogoniometer at different velocities ranging from 0.2 to 8 rad s-1. EMG signals from the rectus femoris and medial hamstrings muscles were collected with surface electrodes. The relations between velocity and: the resistance at the beginning of motion, work done to move a limb, and maximum activation of the rectus femoris and hamstrings muscle...
Article
The aim of this study was to examine measures of health-related quality of life (HRQL) in children with cerebral palsy (CP) by comparing scores of a generic HRQL measure, the Child Health Questionnaire (CHQ); a disease-specific HRQL measure for children with CP, the Caregiver Questionnaire (CQ); and a pediatric functional measure, the Wee-Functiona...
Article
In this descriptive study, the Wee-Functional Independence Measure (WeeFIM) was used to document functional change in children with cerebral palsy after orthopedic surgery and physical therapy. The study sample consisted of 20 children between the ages of four and 12 years with a diagnosis of spastic cerebral palsy. The subjects' WeeFIM scores coll...
Article
The results of selective posterior rhizotomy in fifty patients (group I) and of soft-tissue procedures in fifty patients (group II), all 100 of whom had cerebral diplegia and were seen in a private office, were reviewed retrospectively. No effort was made to randomize the treatment, as the selection criteria for the two procedures are different. We...
Article
The incidence of deep vein thrombosis (DVT) in the disabled pediatric population has rarely been studied. The purpose of our retrospective study was to define the incidence in patients younger than 18 years of age who were in a rehabilitation center. We reviewed the charts of 532 children admitted to the center from 1983 through 1987, and found a 2...
Article
Functional outcome studies after treatment of primary brain tumors in children are lacking. This study of 30 children, ages 3 to 20 years (x 10.8 yrs) was aimed at documenting the effects of rehabilitation on functional outcome after treatment of primary brain tumors. Functional measurements were documented by a modified functional independence mea...
Article
Superior mesenteric artery syndrome is a condition in which the third portion of the duodenum is intermittently compressed by the overlying superior mesenteric artery, resulting in gastrointestinal obstruction. Predisposing factors include rapid weight loss, prolonged supine positioning, and using a spinal orthosis, all of which are common among ac...