Debanjan Mukherjee

Debanjan Mukherjee
University of Colorado Boulder | CUB · Department of Mechanical Engineering (ME)

Doctor of Philosophy

About

32
Publications
3,724
Reads
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171
Citations
Additional affiliations
January 2019 - present
University of Colorado Boulder
Position
  • Professor (Assistant)
August 2018 - January 2019
University of Colorado Boulder
Position
  • Professor (Assistant)
January 2014 - August 2018
University of California, Berkeley
Position
  • PostDoc Position
Description
  • Numerical modeling of cardiovascular flows, and coupled particle-laden flows in the human circulatory system.
Education
May 2010 - December 2013
University of California, Berkeley
Field of study
  • Mechanical Engineering - Computational Mechanics
August 2008 - May 2010
University of California, Berkeley
Field of study
  • Mechanical Engineering - Fluids
August 2004 - July 2008
Indian Institute of Technology Madras
Field of study
  • Ocean Engineering

Publications

Publications (32)
Article
Biofluids comprises a core topical domain for modern biomedical engineering education. Like other biomedical topic areas, biofluids education must address highly inter-disciplinary and applied topics. Concept/problem based active learning approaches can provide effective avenues to teach such diverse and applied topics. However, with the heterogene...
Article
The ongoing SARS-CoV-2 (Covid-19) pandemic has ushered an unforeseen level of global health and economic burden. As a respiratory infection, Covid-19 is known to have a dominant airborne transmission modality, wherein fluid flow plays a central role. The quantification of complex non-intuitive dynamics and transport of pathogen laden respiratory pa...
Preprint
The ongoing SARS-CoV-2 (Covid-19) pandemic has ushered an unforeseen level of global health and economic burden. As a respiratory infection, Covid-19 is known to have a dominant airborne transmission modality, wherein fluid flow plays a central role. Quantification of complex non-intuitive dynamics and transport of pathogen laden respiratory partic...
Article
Flow-mediated transport of biochemical species is central to thrombotic phenomena. Comprehensive three-dimensional modeling of flow-mediated transport around realistic macroscale thrombi poses challenges owing to their arbitrary heterogeneous microstructure. Here, we develop a microstructure aware model for species transport within and around a mac...
Article
Full-text available
A pathologically formed blood clot or thrombus is central to major cardiovascular diseases like heart attack and stroke. Detailed quantitative evaluation of flow and flow-mediated transport processes in the thrombus neighborhood within large artery hemodynamics is crucial for understanding disease progression and assessing treatment efficacy. This,...
Preprint
Flow-mediated transport of biochemical species is central to thrombotic phenomena. Comprehensive three-dimensional modeling of flow-mediated transport around realistic macroscale thrombi poses challenges owing to their arbitrary heterogeneous microstructure. Here, we develop a microstructure aware model for species transport within and around a mac...
Article
Here we describe a systematic approach towards creating effective screencast based modules for teaching computational techniques in remote and online modalities. We adopted a multi-stage approach to create screencast videos that replaced in-person demos and active learning content in a finite element analysis based class. The stages include systema...
Article
Full-text available
We investigated the effects of atherosclerosis in the carotid region on cerebral haemodynamics. A total of 15 stenosis cases following NASCET criteria were modelled using patient-specific medical image data and an open-source package, SimVascular. The formulation adopted the stabilised Petrov–Galerkin scheme with Newtonian and incompressible assump...
Article
Full-text available
Haemodynamic correlations among the pulsatility index (PI), resistive index (RI), time to peak velocity (TPV), and mean Reynolds number (ReMean) were numerically investigated during the progression of carotid stenosis (CS), a highly prevalent condition. Fifteen patient-specific CS cases were modeled in the package, SimVascular, by using computed to...
Article
Background: Isolation space must be expanded during pandemics involving airborne transmission. Little to no work has been done to establish optimal design strategies and implementation plans to ease surge capacity and expand isolation capacity over long periods in congregate living facilities. The COVID-19 pandemic has an airborne transmission com...
Preprint
Full-text available
Background: Isolation space must be expanded during pandemics involving airborne transmission. Little to no work has been done to establish optimal design strategies and implementation plans to ease surge capacity and expand isolation capacity over long periods in congregate living facilities. The COVID-19 pandemic has an airborne transmission comp...
Preprint
A pathologically formed blood clot or thrombus is central to major cardiovascular diseases like heart attack and stroke. Detailed quantitative evaluation of flow and flow-mediated transport processes in the thrombus neighborhood within large artery hemodynamics is crucial for understanding disease progression and assessing treatment efficacy. This,...
Article
Full-text available
A hybrid, multiscale, particle–continuum numerical method is developed for resolving the interaction of a realistic thrombus geometry with unsteady hemodynamics typically occurring within large arteries. The method is based on a discrete particle/element description of the thrombus, coupled to blood flow using a fictitious domain finite element met...
Article
We describe a patient-specific simulation based investigation on the role of Circle of Willis anatomy in cardioembolic stroke. Our simulation framework consists of medical image-driven modeling of patient anatomy including the Circle, 3D blood flow simulation through patient vasculature, embolus transport modeling using a discrete particle dynamics...
Preprint
We describe a patient-specific simulation based investigation on the role of Circle of Willis anatomy in cardioembolic stroke. Our simulation framework consists of medical image-driven modeling of patient anatomy including the Circle, 3D blood flow simulation through patient vasculature, embolus transport modeling using a discrete particle dynamics...
Article
The complexity of inertial particle dynamics through swirling chaotic flow structures characteristic of pulsatile large-artery hemodynamics renders significant challenges in predictive understanding of transport of such particles. This is specifically crucial for arterial embolisms, where knowledge of embolus transport to major vascular beds helps...
Article
Stroke caused by an embolism accounts for about a third of all stroke cases. Understanding the source and cause of the embolism is critical for diagnosis and long-term treatment of such stroke cases. The complex nature of the transport of an embolus within large arteries is a primary hindrance to a clear understanding of embolic stroke etiology. Re...
Article
A modular discrete element framework is presented for large-scale simulations of industrial grain-handling systems. Our framework enables us to simulate a markedly larger number of particles than previous studies, thereby allowing for efficient and more realistic process simulations. This is achieved by partitioning the particle dynamics into disti...
Article
Full-text available
Roughly one-third of all strokes are caused by an embolus traveling to a cerebral artery and blocking blood flow in the brain. The objective of this study is to gain a detailed understanding of the dynamics of embolic particles within arteries. Patient computed tomography image is used to construct a three-dimensional model of the carotid bifurcati...
Article
This work presents a computer simulation framework based on discrete element method to analyze manufacturing processes that comprise a loosely flowing stream of particles in a carrier fluid being deposited on a target surface. The individual particulate dynamics under the combined action of particle collisions, fluid–particle interactions, particle...
Article
The general problem of a loosely flowing erosive granular jet undergoing impact with a compliant surface is common in many manufacturing processes, and also in the operating environment of a variety of machine parts. This paper presents a three-dimensional, collision-driven discrete particle simulation framework for investigating the dynamics of a...
Article
Virtually all engineering applications involve the use of piping, conduits, and channels. In the petroleum industry, piping systems are extensively used in upstream and downstream processes. These piping systems often carry fluids that are corrosive, which leads to wear, cavitation, and cracking. The replacement of damaged piping systems can be qui...
Article
Virtually all engineering applications involve the use of piping, conduits and channels. In the petroleum industry, piping systems are extensively employed in upstream and downstream processes. These piping systems often carry fluids that are corrosive, which leads to wear, cavitation and cracking. The replacement of damaged piping systems can be q...
Conference Paper
Full-text available
Particulate media are ubiquitous in modern manufacturing processes. These include spray-forming, abrasive finishing, and sintering based processes amongst others. All of these processes involve a flowing stream of discrete, particulate media. For these processes, the aggregate behavior originating from the individual particle or grain dynamics is o...
Conference Paper
Full-text available
The process of decommissioning ships, usually followed by ship scraping, is associated not only with significant costs but also with many environmental and toxic hazards. Thus, re usability of such ships will offer more advantages than recycling its steel. This paper proposes reusing a post-service life vessel by converting it into an Ocean Wave En...

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