
David van der ZeeUniversity Medical Center Utrecht | UMC Utrecht · Department of Surgery
David van der Zee
MD., PhD
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323
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Introduction
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April 1980 - June 1986
Publications
Publications (323)
Background:
Esophageal replacement (ER) with gastric pull-up (GPU) or jejunal interposition (JI) used to be the standard treatment for long-gap esophageal atresia (LGEA). Changes of the ER grafts on a macro- and microscopic level however, are unknown.
Aim:
To evaluate long-term clinical symptoms and anatomical and mucosal changes in adolescents...
Esophageal atresia (EA) is a rare birth defect in which respiratory tract disorders are a major cause of morbidity. It remains unclear whether respiratory tract disorders are in part caused by alterations in airway epithelial cell functions such as the activity of motile cilia. This can be studied using airway epithelial cell culture models of pati...
Background:
Esophageal atresia (EA) is most often accompanied by some degree of tracheomalacia (TM), which negatively influences the airway by ineffective clearance of secretions. This can lead to lower airway bacterial colonization (LABC), which may cause recurrent respiratory tract infections (RTIs). This study aims to evaluate the prevalence an...
Many consider the repair of esophageal atresia and tracheoesophageal fistula the quintessential pediatric surgical operation. While the operation for repair of the most common types is certainly elegant and gratifying, there remain controversies and pitfalls to be considered, and the more uncommon varieties of the disease can be some of the most ch...
Background:
Present theory is that uncomplicated and complicated appendicitis are different entities. Recent studies suggest it is safe to delay surgery in patients with uncomplicated appendicitis. We hypothesize that patients with complicated appendicitis are at higher risk for postoperative complications when surgery is delayed.
Methods:
Data...
Background: Esophageal atresia (EA) is often accompanied by tracheomalacia (TM). TM can lead to severe respiratory complaints requiring invasive treatment. This study aims to evaluate if thoracoscopic primary posterior tracheopexy (PPT) can prevent the potential sequelae of TM in patients with EA.
Methods: A cohort study including all consecutive E...
Background: Esophageal atresia (EA) is a rare congenital malformation of the esophagus. Surgical treatment is required to restore the continuity of the esophagus. This can be performed through thoracotomy. However, an increasing number of hospitals is performing minimal invasive surgery (MIS). In this article, we describe the technique of thoracosc...
The definition of long gap esophageal atresia in the past has always been controversial. In a recent position paper on long gap esophageal atresia, the definition was clearly determined as those types of atresia that had no air on plain abdominal X-rays, that is, type A and B.
The management of long-gap esophageal atresia (LGEA) has always been a challenge. The native esophagus is the best option and should be preserved as much as possible. Many centers apply the delayed primary anastomosis technique (wait and watch technique) with anastomosis within 2–4 months. With the advances in minimal invasive surgery techniques in...
Background: Thoracoscopic external traction technique (TTT) is a relatively new surgical intervention for patients with long-gap esophageal atresia (LGEA) that preserves the native esophagus. The major accomplishment with TTT is that esophageal repair can be achieved within days after birth.
This study evaluates the childhood outcome in LGEA patien...
Background
Gastroesophageal reflux disease (GERD) is a common disease in children. When drug treatment fails, laparoscopic anti-reflux surgery (LARS) is considered. Short-term follow-up studies report high success rates; however, few studies report long-term results. The aim of this study was to describe the long-term effects of LARS in pediatric p...
Introduction Evidence supporting best practice for long-gap esophageal atresia is limited. The European Reference Network for Rare Inherited Congenital Anomalies (ERNICA) organized a consensus conference on the management of patients with long-gap esophageal atresia based on expert opinion referring to the latest literature aiming to provide clear...
IntroductionIn patients treated with an appendectomy for acute appendicitis, the specimen is generally sent for histological evaluation. In an era of increasing non-operative treatment for acute appendicitis, it is important to know the incidence, the diagnostic accuracy, and treatment consequences of appendicular neoplasms that are found in acute...
Purpose
Assessing quality of life (QoL) after esophageal replacement (ER) for long gap esophageal atresia (LGEA).
Methods
All patients after ER for LGEA with gastric pull-up (GPU n = 9) or jejunum interposition (JI n = 14) in University Medical Center Groningen and Utrecht (1985–2007) were included. QoL was assessed with 1) gastrointestinal-relate...
Introduction:
Many studies on short-term efficacy of laparoscopic antireflux surgery (LARS) have shown good to excellent results on reflux symptom control and health-related quality of life (HRQoL). Prospective studies on the long-term efficacy, however, are scarce and indicate that the efficacy of symptom control may decline over time. The aim of...
Introduction
A gastrostomy placement (GP) is an established treatment to provide enteral feeding in pediatric patients with feeding difficulties aiming to improve nutritional status and health-related quality of life (HRQoL). The aim of this study was to evaluate HRQoL in children with severe feeding difficulties who have undergone GP.
Materials a...
Introduction Improvements in care of patients with esophageal atresia (EA) and tracheoesophageal fistula (TEF) have shifted the focus from mortality to morbidity and quality-of-life. Long-term follow-up is essential, but evidence is limited and standardized protocols are scarce. Nineteen representatives of the European Reference Network for Rare In...
Pancreatic tumors in children are rare [1]. A 38-year retrospective single-institute study revealed only 14 patients with pseudopapillary neoplasms being the most frequent with 6 cases, followed by insulinoma (N = 3). There were two neoplastic tumors. Furthermore focal or diffuse hyperinsulinism in infancy may be encountered [2, 3].
Introduction Many aspects of the management of esophageal atresia (EA) and tracheoesophageal fistula (TEF) are controversial and the evidence for decision making is limited. Members of the European Reference Network for Rare Inherited Congenital Anomalies (ERNICA) conducted a consensus conference on the surgical management of EA/TEF based on expert...
Background
Long-gap esophageal atresia (LGEA) is defined as atresia without distal tracheoesophageal fistula. Preserving the native esophagus is considered superior over intestinal interposition. Thoracoscopic traction technique facilitates lengthening of the esophageal ends, and allows anastomosis within the first weeks of life. The aim of this st...
Background
Esophageal atresia (EA) is usually accompanied by some form of tracheomalacia. During the early phases in life, excessive dynamic collapse of the trachea can cause a wide spectrum of symptoms ranging from mild complaints to apparent life-threatening events (ALTE’s). Therapeutic strategies for severe tracheomalacia include aortopexy to li...
Background and purpose:
A gastrostomy placement (GP) aims to improve nutritional status and health-related quality of life (HRQoL) in children who require long-term enteral tube feeding. We evaluated the effect of GP on HRQoL.
Methods:
A prospective, longitudinal cohort study was performed including patients referred for laparoscopic GP. Childre...
Esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) represents a congenital developmental anomaly. It is the most common congenital malformation of the esophagus characterized by an esophageal discontinuity (the upper esophagus terminates in a blind-ending pouch) and a possible tracheoesophageal connection [1–3].
Esophageal atresia (EA) repair has always been a source of immense professional gratification for the pediatric surgeon. In many ways, this anomaly defines the entire profession. Due to its rarity, there is an increased risk of inadvertent events occurring during correction. This article describes some of the error traps that may occur in attemptin...
This chapter describes the evolution from delayed management of long-gap oesophageal atresia to thoracoscopic treatment directly after birth without the placement of a gastrostomy. Long-gap oesophageal atresia remains a challenge for pediatric surgeons. Over the years several techniques have been described to manage long-gap oesophageal atresia. Mo...
Congenital oesophageal strictures are rare and are commonly associated with cartilaginous rings. Surgical intervention in congenital stenosis in shown to be beneficial with very good outcome. Acquired oesophageal strictures in children are related to severe gastro-oesophageal reflux, anastomosis and accidental ingestion of corrosive bleach or butto...
Background:
Esophageal atresia (EA) is usually accompanied by some form of tracheomalacia (TM). During the early phases in life, excessive dynamic collapse of the trachea can cause a wide spectrum of symptoms ranging from mild complaints to apparent life-threatening events (ALTE's) or brief resolved unexplained events (BRUE's). Therapeutic strateg...
Background:
Gross genetic causes for SCT are unknown; however, it might be associated with other abnormalities. We assessed the incidence of associated abnormalities in a large national cohort of neonates with SCT and aimed to identify predictive risk factors.
Procedure:
The medical records were reviewed of 235 consecutive neonates with SCT trea...
The laparoscopic management of duodenal obstruction is challenging but feasible and has a good outcome. The procedure is technical demanding and usually requires an experienced laparoscopic surgeon.
In patients with long-gap esophageal atresia, the native esophagus alone is not always sufficient to create esophageal continuity. While delayed primary anastomosis or traction techniques should be attempted first, the small bowel, stomach, or colon may ultimately be required to bridge the ends of the atretic esophagus.KeywordsEsophageal atresiaLon...
Objective
Neonates have a high risk of oxidative stress during anesthetic procedures. The predictive role of oxidative stress biomarkers on the occurrence of brain injury in the perioperative period has not been reported before.
Methods
A prospective cohort study of patients requiring major surgery in the neonatal period was conducted. Biomarker l...
Esophageal atresia is an anomaly with frequently occurring sequelae requiring lifelong management and follow-up. Because of the complex issues that can be encountered, patients with esophageal atresia preferably should be managed in centers of expertise that have the ability to deal with all types of anomalies and sequelae and can perform rigorous...
Introduction
The aim of the current study was to determine the effect of general anesthesia on neonatal brain activity using amplitude-integrated EEG (aEEG).
Methods
A prospective cohort study of neonates (January 2013-December 2015), who underwent major neonatal surgery for non-cardiac congenital anomalies. Anesthesia was administered at the disc...
Supporting information.
(XLSX)
Differences between thoracoscopic and non-thoracoscopic procedures.
(DOCX)
Correlation ISI-values and background patterns.
(DOCX)
Introduction:
Improving health-related quality of life (HRQoL) is increasingly recognized as an essential part of patient care outcome. Little is known about the effect of laparoscopic antireflux surgery (LARS) on the HRQoL in the pediatric patients. The aims of this study were to evaluate the effect of LARS on HRQoL in children with gastroesophag...
Background:
Esophageal intraluminal baseline impedance reflects the conductivity of the esophageal mucosa and may be an instrument for in vivo evaluation of mucosal integrity in children with gastroesophageal reflux disease (GERD). Laparoscopic antireflux surgery (LARS) is a well-established treatment option for children with proton pump inhibitor...
Introduction:
A choledochal malformation (CM) is a rare entity, especially in the Western world. We aimed to determine the incidence of CM in the Netherlands and the outcome of surgery for CM in childhood.
Methods:
All pediatric patients who underwent a surgical procedure for type I-IV CM between 1989 and 2014 were entered into the Netherlands S...
Background:
A gastrostomy placement is frequently performed in pediatric patients who require long-term enteral tube feeding. Unfortunately, postoperative complications such as leakage, feeding intolerance, and gastroesophageal reflux frequently occur. These complications may be due to postoperative gastric dysmotility. Our aim was to evaluate the...
INoEA is the International Network of Esophageal Atresia and consists of a broad spectrum of pediatric specialties and patient societies. The working group on long-gap esophageal atresia (LGEA) set out to develop guidelines regarding the definition of LGEA, the best diagnostic and treatment strategies, and highlight the necessity of experience and...
Esophageal atresia has always been the hallmark of pediatric surgery. Long-gap esophageal atresia (LGEA) has been a challenge for many pediatric surgeons for many decades. Several alternative techniques have past the revenue, some to stay, and some to go. As early as in the late 1950s of the past century, Rehbein [1] already described the approxima...
Introduction:
Laparoscopic antireflux surgery (LARS) in children primarily aims to decrease reflux events and reduce reflux symptoms in children with therapy-resistant gastroesophageal reflux disease (GERD). The aim was to objectively assess the effect and efficacy of LARS in pediatric GERD patients and to identify parameters associated with failu...
Introduction:
Choledochal malformations (CMs) are increasingly diagnosed antenatally. There is a dilemma between early surgery to prevent CM-related symptoms and postponing surgery to reduce complications. We aimed to identify the optimal timing of surgery in asymptomatic neonates with antenatally diagnosed CM and to identify predictors for develo...
Background:
Children born with esophageal atresia require an anastomosis between the proximal and distal esophagus. When this distance is too wide (long gap esophageal atresia, LGEA) esophageal replacement strategies have to be deployed. The aim of this study was to assess long-term respiratory morbidity and lung function after esophageal replacem...
Aim:
This study aimed to report the results of a multicentric survey about laparoscopic treatment of pancreatic tumors in children.
Materials and methods:
The data of patients operated using minimally invasive surgery (MIS) for a pancreatic tumor in 5 International centers of Pediatric Surgery in the last 5 years were retrospectively reviewed. W...
Management of esophageal atresia has merged from correction of the anomaly to the complete spectrum of management of esophageal atresia and all its sequelae. It is the purpose of this article to give an overview of all aspects involved in taking care of patients with esophageal atresia between January 2011 and June 2016, as well as the patients who...
Background:
Elongation and repair of long gap esophageal atresia (LGEA) can be performed thoracoscopically, even directly after birth. The effect of thoracoscopic CO2-insufflation on cerebral oxygenation (rScO2) during the consecutive thoracoscopic procedures in repair of LGEA was evaluated.
Methods:
Prospective case series of five infants, with...
Supplemental Table 1. Overview of congenital anomalies. Supplemental table 2. Statistics of Wilcoxon Signed Rank test.
Objective:
To evaluate the incidence of brain injury after neonatal surgery for noncardiac congenital anomalies using magnetic resonance imaging (MRI).
Study design:
An MRI was obtained in 101 infants at 7 days [range: 1-115] after neonatal surgery for major noncardiac congenital anomalies. Brain injury was assessed using T1, T2, diffusion weigh...
Paediatric endoscopic surgery is greatly indebted to Karl Storz for developing paediatric endoscopic instruments. In more recent years, there is an increasing interest in endoscopic surgery in neonates. Now more complex procedures are being performed, although it will take another generation before these will be more generally applied. One of the k...
Background
Little is known about the effects of carbon dioxide (CO2) insufflation on cerebral oxygenation during thoracoscopy in neonates. Near-infrared spectroscopy can measure perioperative brain oxygenation [regional cerebral oxygen saturation (rScO2)].
Aims
To evaluate the effects of CO2 insufflation on rScO2 during thoracoscopic esophageal atr...
Background:
A small percentage of neonates with sacrococcygeal teratoma die shortly after birth from hemorrhagic complications. The incidence of and risk factors associated with hemorrhagic mortality are unknown. In this multicenter study we determined the incidence of early death in neonates born with SCT and evaluated potential risk factors for...
Objectives:
A novel automated 3-dimensional (3D) sonographic method has been developed for measuring gastric volumes. This study aimed to validate and assess the reliability of this novel 3D sonographic method compared to the reference standard in 3D gastric sonography: freehand magneto-based 3D sonography.
Methods:
A prospective study with 8 ba...
Background:
Percutaneous endoscopic gastrostomy (PEG) and laparoscopic-assisted gastrostomy (LAG) are widely used in the paediatric population. The aim of this study was to determine which one of the two procedures is the most effective and safe method.
Methods:
This systematic review was conducted according to the preferred reporting items for...
Background:
Laparoscopic antireflux surgery (LARS) is a well-established treatment option for children with proton pomp inhibitor (PPI)-resistant gastroesophageal reflux disease (GERD). Besides preventing reflux of gastric fluid and solid content, LARS may also impair the ability of the stomach to vent intragastric air (i.e. gastric belching) and...
To investigate gastric accommodation, accurate measurements of gastric volumes are necessary. An excellent technique to measure gastric volumes is dynamic magnetic resonance imaging (MRI). Unfortunately, dynamic MRI is expensive and not always available. A new 3-D ultrasound (US) method using a matrix transducer was developed to measure gastric vol...
Introduction
An increasing percentage of surgical interventions in neonates is performed by minimal invasive techniques. Recently, concerns have been raised regarding a decrease of cerebral oxygenation in neonates during thoracoscopy.
Aim
To evaluate the effect of CO2-insufflation with 5 and 10 mmHg on cerebral oxygenation and hemodynamics in neon...
Introduction
Neonates undergoing surgery for congenital anomalies are at risk of adverse neurodevelopmental outcomes, possibly due to perioperative cerebral damage. Near infrared spectroscopy (NIRS) can be applied to measures perioperative regional cerebral oxygen saturation (rScO2). Little is known about the effects of carbon dioxide (CO2)-insuffl...
Purpose:
The impact of chemotherapeutic sequelae on long-term quality of life (QoL) for survivors of malignant sacrococcygeal teratoma (SCT) is unknown. The incidence of chemotherapeutic toxicity in patients treated for malignant SCT and possible effects on the QoL were analyzed.
Methods:
Retrospective chart review of patients ≥18 years treated...
Context:
Increasing concerns have been raised about the incidence of neurodevelopmental delay in children with noncardiac congenital anomalies (NCCA) requiring neonatal surgery.
Objective:
This study aimed to determine the incidence and potential risk factors for developmental delay after neonatal surgery for major NCCA.
Data sources:
A system...
Background:
To evaluate defecation and micturition complaints in adults treated for sacrococcygeal teratoma (SCT) during childhood and to identify risk factors for soiling, urinary incontinence, and constipation beyond childhood.
Procedure:
Records of patients aged ≥18 treated for SCT during infancy in the Netherlands were retrospectively review...
Objective:
To assess incidence and clinical course of Dutch patients with achalasia diagnosed before 18 years of age as well as their current symptoms and quality of life (QoL).
Study design:
Retrospective medical chart review and a cross-sectional study assessing current clinical status using the Eckardt score and reflux disease questionnaire....
Background:
Research in postoperative mortality is scarce. Insight into mortality and cause of death might improve and innovate perioperative care. The objective for this study was to report the 24-hour and 30-day overall, and surgery and anaesthesia-related, in-hospital mortality at a tertiary paediatric hospital.
Methods:
All patients <18 yr o...
Background:
Children treated for sacrococcygeal teratoma (SCT) may suffer from sexual dysfunction later in life because of the extended pelvic surgery performed, however, structured evaluations have not been performed yet.
Methods:
The Female Sexual Function Index (FSFI), the International Index of Erectile Function (IIEF) and the Body Image Que...
Progressive familial intrahepatic cholestasis (PFIC) with low gamma-glutamyl transpeptidase (GGT) and Alagille syndrome are associated with persistent cholestasis and severe pruritus. Various types of biliary diversion have been used to reduce this pruritus and prevent liver dysfunction. We report our experience concerning the efficacy and safety o...
Malrotation occurs when there is a failure in the intestinal rotation leading to abnormal fixation to the abdominal wall and a mesentery with a short root. Volvulus is a life-threatening complication of malrotation. It can lead to irreversible intestinal necrosis and requires immediate attention. Early recognition of malrotation and surgical correc...
The aim of this study was to investigate whether younger age at surgery is associated with the increased incidence of postoperative complications after prophylactic thyroidectomy in pediatric patients with multiple endocrine neoplasia (MEN) 2.
The shift toward earlier thyroidectomy has resulted in significantly less medullary thyroid carcinoma (MTC...
Objectives:
The aim of the study was to compare parent proxy-reports with that of self-reports of children with anorectal malformations (ARM) or Hirschsprung's disease (HD) and healthy siblings and thereafter was examined whether these comparisons differed between patients and their siblings.
Methods:
Parents (n = 98) of either children with ARM...
Concern remains about the safety of carbon dioxide (CO2) pneumoperitoneum (PP) in young infants having surgery for pyloric stenosis via laparoscopy. Interests here mainly focus on possible jeopardized organ perfusion and in particular brain oxygenation with possible adverse neurodevelopmental outcomes. The aim of this study was to investigate the i...
A conglomerate of European pediatric surgeons [1], united in the anorectal malformations network (ARMs-Net), refined the ‘Krickenbeck classification’ [2] that has served as a gold standard for the clinical management of anorectal malformations (ARM) over the past decade.With expanding experience when dealing with ARM and continuing improvement in d...
To describe the evolution from delayed management of long gap esophageal atresia to thoracoscopic treatment directly after birth without the placement of a gastrostomy.
Long gap esophageal atresia remains a challenge for pediatric surgeons. Over the years, several techniques have been described to deal with the problem of the distance between the p...
Objective This study aims to develop a set of quality indicators for the measurement of the quality of surgical care for neonates with surgical disorders. Methods An expert panel of the Netherlands Association of Pediatric Surgeons developed internal (clinical) indicators for neonatal surgery. This included the selection of appropriate care process...
Children treated for sacrococcygeal teratoma (SCT) may experience functional sequelae later in life. It is not known whether SCT and associated problems affect the patient's general quality of life (QoL). In a national survey, we evaluated general QoL in adults treated for SCT during childhood and compared the results to reference values for the Du...