David Rankin- PhD
- Research Fellow at University of Edinburgh
David Rankin
- PhD
- Research Fellow at University of Edinburgh
About
89
Publications
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Introduction
My expertise is in qualitative health research and I have been involved in several high-quality projects which have explored patients’, partners’/family members’ and health professionals’ views about and experiences of managing type 1 diabetes. My main areas of work include: the DAFNEplus programme grant which aims to re-develop and evaluate the DAFNE programme to help people with type 1 diabetes to better manage their condition in line with their lifestyle; and the CLOuD study which is exploring whether Closed Loop technology can preserve the function of beta cells in young people who have recently been diagnosed with type 1 diabetes better than standard treatment (multiple daily injections).
Current institution
Additional affiliations
June 2002 - present
Education
September 2004 - May 2010
August 1998 - June 2000
October 1992 - July 1996
Publications
Publications (89)
Objectives
Type 1 diabetes can have life-shattering consequences for adolescents and parents. A closed-loop system is a cutting-edge technology which automatically regulates glucose to reduce the burden of diabetes management. We explored adolescents’ and parents’ experiences of using this technology to understand how it affects their biographies a...
Background:
Closed-loop technology may help address health disparities experienced by adolescents, who are more likely to have suboptimal glycemic control than other age groups and, because of their age, find diabetes self-management particularly challenging. The CamAPS FX closed-loop has sought to address accessibility and usability issues report...
Aims:
To explore the everyday experiences of children (aged ≤ 12 years) with Type 1 diabetes to identify factors that help or hinder diabetes self-management practices.
Methods:
Eight databases (Embase, Medline, CINAHL, Web of Science, PsychInfo, ASSIA, ERIC and ProQuest Dissertations) were searched in 2016 to identify qualitative studies explor...
Background:
Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access historical data to inform treatment decisions. While the clinical and psychological benefits of CGM are well established, little is...
Aims
To synthesise the qualitative evidence on parents’ experiences of caring for a child aged ≤8 years with type 1 diabetes to identify: the challenges they encounter; their views about support received; ways in which support could be improved; and, directions for future research.
Methods
We searched Medline, EMBASE, CINAHL, PsycINFO and Web of S...
Aims
To understand and explore the strategies, resources, and interventions healthcare professionals are implementing, or recommend implementing, to promote more equitable access to diabetes technology amongst children and young people (CYP) with type 1 diabetes in the UK.
Methods
Interviews were conducted with ( n = 29) healthcare professionals w...
Background
There is a lack of practical guidance about how to effectively mobilise knowledge at the pre-trial stage. Despite increased guidance on developing complex interventions in recent years, much of this focuses on the theory and principles behind high-quality intervention development, rather than the practical aspects of how this should be a...
Aims
We explored healthcare professionals' perceptions and understandings of the factors and considerations underlying inequities in technology access in children and young people (CYP) with type 1 diabetes.
Methods
We interviewed ( n = 29) healthcare professionals working in paediatric diabetes in England recruited from ( n = 15) purposively sele...
Aims
The DAFNE plus programme incorporates behaviour change techniques into a modified educational intervention and was developed to help address the glycaemic drift observed amongst graduates of standard DAFNE programmes. As the programme's success will be contingent on staff buy‐in, we explored healthcare professionals' experiences of, and views...
Aims
The DAFNE plus programme seeks to promote sustained improvements in glycaemic management by incorporating techniques from behavioural science. It includes five sessions of structured individual support delivered over 12 months following group education. As part of a broader evaluation, and to inform decision‐making about roll‐out in routine ca...
( N Engl J Med. 2023;389:1566–1578)
Type 1 diabetes often causes significant complications both during pregnancy and immediately after delivery for both mother and infant. This makes glycemic control during pregnancy for these women of utmost importance for their health and that of their baby. Several therapies have been introduced for pregnancies...
Background
We assessed whether a sustained period of intensive glucose control with hybrid closed-loop for 12 months following diagnosis of type 1 diabetes in children and adolescents can preserve C-peptide secretion compared to standard insulin therapy.
Methods
In an open-label, multicentre, randomised, parallel trial, youth aged 10–16.9 years we...
(Abstracted from N Engl J Med 2023;389:1566–1578
Hyperglycemia during pregnancy is an important risk factor for complications, such as preterm birth, large birth weight, and admission to the intensive care unit. Those at highest risk already have glycated hemoglobin above target levels at the start of pregnancy.
Background
There are over 2000 pregnancies annually in women with type 1 diabetes in the UK. Despite recent improvements in diabetes technology, most women cannot achieve and maintain the recommended pregnancy glucose targets. Thus, one in two babies experience complications requiring neonatal care unit admission. Recent studies demonstrate that hy...
Aims
As part of a broader process evaluation, we explored participants' experiences of, and engagement with, the DAFNEplus programme's group-based structured education course. This course, which was informed by behavioural science, provided participants with education and instruction to use flexible intensive insulin therapy (FIIT) together with te...
Background
There is a lack of practical guidance about how to effectively mobilise knowledge at the pre-trial stage. Despite increased guidance on developing complex interventions in recent years, much of this focuses on the theory and principles behind high quality intervention development, rather than the practical aspects of how this should be a...
Background:
Hybrid closed-loop insulin therapy has shown promise for management of type 1 diabetes during pregnancy; however, its efficacy is unclear.
Methods:
In this multicenter, controlled trial, we randomly assigned pregnant women with type 1 diabetes and a glycated hemoglobin level of at least 6.5% at nine sites in the United Kingdom to rec...
Introduction:
Recent high-profile calls have emphasized that women's experiences should be considered in maternity care provisioning. We explored women's experiences of using closed-loop during type 1 diabetes pregnancy to inform decision-making about antenatal rollout and guidance and support given to future users.
Methods:
We interviewed 23 cl...
Background:
Interest is growing in how closed-loop systems can support attainment of within-target glucose levels amongst pregnant women with type 1 diabetes. We explored healthcare professionals' views about how, and why, pregnant women benefitted from using the CamAPS FX system during the AiDAPT trial.
Methods:
We interviewed 19 healthcare pro...
Aims:
To explore healthcare professionals' views about the training and support needed to rollout closed-loop technology to pregnant women with type 1 diabetes.
Methods:
We interviewed (n=19) healthcare professionals who supported pregnant women using CamAPS FX closed-loop during the AiDAPT trial. Data were analysed descriptively. An online work...
Background
Pregnant women with type 1 diabetes strive for tight glucose targets (3.5-7.8 mmol/L) to minimise the risks of obstetric and neonatal complications. Despite using diabetes technologies including continuous glucose monitoring (CGM), insulin pumps and contemporary insulin analogues, most women struggle to achieve and maintain the recommend...
Objectives:
We explored parents' views about healthcare professionals having remote access to their young child's insulin and glucose data during a clinical trial to inform use of data sharing in routine paediatric diabetes care.
Methods:
Interviews with 33 parents of 30 children (aged 1-7 years) with type 1 diabetes participating in a randomise...
Aims
To explore parents’ experiences of using a hybrid closed-loop system (CamAPS FX) when caring for a very young child (aged 1-7 years) with type 1 diabetes.
Methods
Interviews with n=33 parents of 30 children who used the system during a randomised controlled trial. Data analysis used a descriptive thematic approach.
Results
While some parents...
Aims:
To explore parents' experiences of using remote monitoring technology when caring for a very young child with type 1 diabetes during a clinical trial.
Methods:
Interviews were conducted with parents of 30 children (aged 1-7 years) participating in a trial (the KidsAP02 study) comparing hybrid closed-loop insulin delivery with sensor-augmen...
Objective:
To understand and explore data sharing practices amongst adolescents and their parents using a closed-loop system.
Methods:
18 adolescents (aged 11-18 years) and 19 parents were interviewed after adolescents had ~6 months experience of using a closed-loop system which permitted them to share glucose and insulin data with parents/careg...
Introduction
The successful treatment of type 1 diabetes (T1D) requires those affected to employ insulin therapy to maintain their blood glucose levels as close to normal to avoid complications in the long-term. The Dose Adjustment For Normal Eating (DAFNE) intervention is a group education course designed to help adults with T1D develop and sustai...
Background:
We explored health professionals' views about the training, support, and resourcing needed to support people using closed-loop technology in routine clinical care to help inform the development of formal guidance.
Methods:
Interviews were conducted with health professionals (n = 22) delivering the Closed Loop from Onset in Type 1 Diabe...
Aim:
To explore health professionals' views about who would benefit from using a closed-loop system and who should be prioritized for access to the technology in routine clinical care.
Methods:
Health professionals (n = 22) delivering the Closed Loop from Onset in type 1 Diabetes (CLOuD) trial were interviewed after they had ≥6 months' experienc...
Background:
Limited attention has been paid to adolescents and young adults' (AYA's) experiences in the aftermath of a cancer diagnosis, despite this being a time when potentially life-changing decisions are made. We explored AYA's and caregivers' experiences of, and views about, making treatment and trial participation decisions following a cance...
Background
While a growing body of research has explored why people take part in clinical trials, this research has not considered how people’s understandings, motivations and agendas might influence their conduct during a trial. This is an important area of enquiry because it is now widely recognised that an intervention might lead to different cl...
Increasing ethical attention and debate is focusing on whether individuals who take part in clinical trials should be given access to post-trial care. However, the main focus of this debate has been upon drug trials undertaken in low-income settings. To broaden this debate, we report findings from interviews with individuals (n ¼ 24) who participat...
Objective:
To explore individuals' experiences of daytime use of a day-and-night hybrid closed-loop system, their information and support needs, and their views about how future systems could be improved.
Research design and methods:
Twenty-four adults, adolescents, and parents were interviewed before using a hybrid day-and-night closed-loop sys...
Aims
To explore whether, how and why moving onto and using a hybrid day‐and‐night closed‐loop system affected people's food choices and dietary practices, to better understand the impact of this technology on everyday life, and to help inform recommendations for training and support given to future users.
Methods
Twenty‐four adults, adolescents an...
Background
People with type 1 diabetes who attend structured education training in self-management using flexible intensive therapy achieve improved blood glucose control and experience fewer episodes of severe hypoglycaemia. However, many struggle to sustain these improvements over time. To inform the design of more effective follow-up support we...
Background
When children with type 1 diabetes approach adolescence, they are encouraged to become more involved in diabetes self-management. This study explored the challenges pre-adolescent children encounter when self-managing diabetes and the factors which motivate and enable them to take on new diabetes-related tasks. A key objective was to inf...
Background
Randomised controlled trials (RCTs) of complex interventions often begin with a pilot phase to test the proposed methods and refine the intervention before it is trialled. Although the Medical Research Council (MRC) recommends regular communication between the practitioners delivering the intervention and the researchers evaluating it du...
Background
While pre‐adolescent children with type 1 diabetes receive most support from their parents/caregivers, others also contribute to their care. This study explored pre‐adolescent children's experiences of receiving diabetes‐related support from friends and peers. The objective was to identify how children could be better supported by their...
Background
Insulin is generally administered to people with type 1 diabetes mellitus (T1DM) using multiple daily injections (MDIs), but can also be delivered using infusion pumps. In the UK, pumps are recommended for patients with the greatest need and adult use is less than in comparable countries. Previous trials have been small, of short duratio...
Background
The ending of a clinical trial may be challenging, particularly if staff are required to withdraw the investigated treatment(s); however, this aspect of trial work is surprisingly under-researched. To address this gap, we explored the experiences of staff involved in closing out a trial that entailed withdrawal of treatment (insulin pump...
To explore health professionals' views about insulin pump therapy [continuous subcutaneous insulin infusion (CSII)] and the types of individuals they thought would gain greatest clinical benefit from using this treatment.
In-depth interviews with staff (n = 18) who delivered the Relative Effectiveness of Pumps Over MDI and Structured Education (REP...
Few studies have identified determinants of glycemic control (HbA1c) and diabetes-specific quality of life (DSQoL) in adults with type 1 diabetes. To identify factors predicting outcomes following structured diabetes education. 262 participants completed biomedical and questionnaire assessments before, and throughout 1 year of follow-up. The propor...
Background
Parents of non-adolescent children with type 1 diabetes are responsible for most of their child’s diabetes management tasks. Consultations are used to provide diabetes education, review clinical progress and promote diabetes management tasks. This study explored parents’ experiences of, and views about, their child’s diabetes consultatio...
The perspectives and experiences of trial staff are increasingly being investigated as these can be used to improve recruitment, adherence to trial protocols and support given to future staff. We interviewed staff working on a type 1 diabetes trial in order to aid interpretation of trial findings, inform recommendations for the rollout of the treat...
Background: Many adults with type 1 diabetes cannot self-manage their diabetes effectively and die
prematurely with diabetic complications as a result of poor glucose control. Following the positive results
obtained from a randomised controlled trial (RCT) by the Dose Adjustment For Normal Eating (DAFNE)
group, published in 2002, structured trainin...
To explore the difficulties parents encounter in trying to achieve clinically recommended blood glucose levels and how they could be better supported to optimize their child's glycaemic control.
In-depth interviews were conducted with 54 parents of children with Type 1 diabetes (≤12 years). Data were analysed thematically.
Parents described being r...
Aims We explored people's reasons for, and experiences of, using bolus advisors to determine insulin doses; and, their likes/dislikes of this technology.
Subjects and methods 42 people with type 1 diabetes who had received instruction in use of bolus advisors during a structured education course were interviewed post-course and 6 months later. Data...
AimsTo compare, in a randomized controlled non-inferiority trial, the outcomes of the traditional format for Dose Adjustment for Normal Eating structured education courses; that is, one delivered over 5 consecutive days (1-week course) with a variant of this format delivered 1 day a week for 5 consecutive weeks (5-week course).Methods
Adults with T...
Aim. To explore patients’ experiences of, views about, and need for, social support after attending a structured education programme for type 1 diabetes.
Background. Patients who attend structured education programmes attain short-term improvements in biomedical and quality-of-life measures but require support to sustain self-management principles...
Background
Children with type 1 diabetes (T1D) experience poor glycaemic control. Among non-adolescent children, parents assume much responsibility for managing diabetes and attaining blood glucose levels within clinically recommended target ranges. We explored parents’ experiences of managing their child’s diabetes and reasons for treatment non-...
Objectives:
To explore the experiences of people who have hypoglycaemia unawareness and its impact on their everyday lives.
Methods:
In-depth interviews with thirty-eight people with Type 1 diabetes who have hypoglycaemia unawareness. Data analysis used an inductive, thematic approach.
Results:
Participants reported imposed and self-imposed chang...
Aim and objectiveThe aim of this study was to describe and explore parents' information and support needs when their child is diagnosed with type 1 diabetes, including their views about the timing and chronology of current support provision. Our objective was to identify ways in which parents could be better supported in the future.Design and parti...
The aim of this study was to explore from parents' perspectives the circumstances and events which led to their child being diagnosed with type 1 diabetes (T1D). The objective was to understand reasons for delays in seeking treatment and parents' emotional reactions to diagnosis so others can be better informed and supported in future.
In-depth int...
Objective Hypoglycaemia Unawareness (HU) affects approximately 25% of people with type 1 diabetes. People with HU are often reliant on family to detect hypoglycaemia and treat severe episodes. We explored the impact of HU on family members’ lives; their involvement in preventing and managing hypoglycaemia; and, their information and support needs....
Aims
Continuous subcutaneous insulin infusion delivered via a pump is increasingly recommended for younger children with type 1 diabetes. We aimed to better understand the impacts on parents who care for young children using insulin pumps. Our objectives were to help interpret psychological outcomes reported in quantitative research and inform prov...
Diabet. Med. 30, 209–215 (2013)
Aims Despite improvements in insulin therapy, hypoglycaemia remains an inevitable part of life for many people with Type 1 diabetes. Little attention has been paid to how individuals self-treat hypoglycaemia and their likes and dislikes of clinically recommended treatments. We explored participants’ experiences of se...
As part of the shift toward patient-centered care, patients are increasingly being consulted about their preferences for health services and interventions, including those explored during randomized controlled trials (RCTs), to ensure that service recommendations are aligned to their own circumstances and needs. Hence, we interviewed patients (N =...
Abstract Background Structured education programmes are now established as an essential component to assist effective self-management of diabetes. In the case of Type 1 diabetes, the Dose Adjustment For Normal Eating (DAFNE) programme improves both glycaemic control and quality of life. Traditionally delivered over five consecutive days, this forma...
OBJECTIVE
To determine whether improvements in glycemic control and diabetes-specific quality of life (QoL) scores reported in research studies for the type 1 diabetes structured education program Dose Adjustment for Normal Eating (DAFNE) are also found when the intervention is delivered within routine U.K. health care.RESEARCH DESIGN AND METHODS
B...
Aim:
To explore patients' experiences of using flexible intensive insulin therapy, a regimen requiring them to determine and adjust quick-acting and background/basal insulin doses and mealtime ratios.
Methods:
Repeat, in-depth interviews with 30 type 1 diabetes patients converted to flexible intensive insulin therapy recruited from Dose Adjustme...
Background
Structured education programmes for patients with diabetes and other chronic conditions are being widely adopted. However, follow-up studies suggest that course graduates may struggle to sustain the self-care practices taught on their courses over time. This study explored the support needs of patients with type 1 diabetes after attendin...
Use of blood glucose targets is considered essential to help patients with Type 1 diabetes achieve tight glycaemic control following structured education. To foster effective use of blood glucose targets, we explored patients' experiences and views of implementing clinically recommended blood glucose targets after attending a structured education p...
Conventional insulin therapy requires patients with Type 1 diabetes to adhere to rigid dietary and insulin injection practices. Recent trends towards flexible intensive insulin therapy enable patients to match insulin to dietary intake and lifestyle; however, little work has examined patients' experiences of incorporating these practices into real-...
Many patients with type 1 diabetes struggle to self-manage this chronic disease, often because they have a poor knowledge and understanding of the condition. However, little attention has been paid to examining the reasons for this poor knowledge/understanding. To inform future educational interventions, we explored patients' accounts of the educat...
To explore whether, and why, patients change their food and eating practices following conversion to flexible intensive insulin therapy (FIIT), a regimen which requires quick acting insulin doses to be matched to the carbohydrate content of meals/snacks consumed.
repeat, in-depth interviews with 30 type 1 diabetes patients converted to FIIT recruit...
This thesis explores processes involved in stakeholders’ attempts to secure sustainability of
three short-term funded community health initiatives known as healthy living centres
(HLCs). The overall aim was to identify and examine development of sustainability
strategies in Scottish HLC organisations. In contrast to retrospective accounts examining...
Objective:
To examine patients' perceptions and experiences over time of the devolvement of diabetes care/reviews from secondary to primary health-care settings.
Design:
Repeat in-depth interviews with 20 patients over 4 years.
Participants and setting:
Twenty type 2 diabetes patients recruited from primary- and secondary-care settings across...
Little is known about how health practitioners tasked with tackling health inequalities account for their own programmes and actions. This paper attempts to address this gap by drawing on data collected in the course of an evaluation of the Healthy Living Centre (HLC) programme, which was designed to address the wider determinants of health, in par...
Objective To explore the diverse roles of drop-in services in the HLC sector; to develop further the classification of drop-in services offered by earlier studies; and to provide an example of some the challenges faced by HLCs in their attempts to tackle poor health using area-based methods with vulnerable, hard-to-reach users.
Setting Scottish Hea...
The Healthy Living Centre (HLC) programme was designed to address the wider determinants of health, in particular social exclusion and socio-economic disadvantage, through targeting services at the most deprived local communities. This paper draws on data collected during an in-depth process evaluation of six Scottish HLC case study sites. Food-rel...
Health promotion is a relatively new discipline and there is little in the way of practical help choosing and implementing appropriate evaluation methods. As the demands for rigorous evaluation and evidence-based decision-making increase, health promotion cannot ignore the need for accurate, reliable, and valid methods to carry out evaluation. This...
Augmentative communication (AC) systems with synthesized speech output have been developed for nonspeaking people. Most AC devices that aim to support social conversation have been designed to help the user generate novel utterances as quickly as possible. However, they remain too slow to support effective, real-time conversation. Preconstructed ph...
