David Mallinson

David Mallinson
University of Strathclyde · Strathclyde Institute of Pharmacy and Biomedical Sciences

Bachelor of Science (Hons) Pharmacology

About

11
Publications
3,240
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
190
Citations

Publications

Publications (11)
Article
Poly (methyl methacrylate) and polyurethane are polymers currently used for a range of biomedical applications. To modify their surface characteristics, biocompatibility and potentially reduce any related side effects the addition to the polymers of appropriate compounds has been investigated. Isatin thiosemicarbazone derivatives were synthesised a...
Article
Full-text available
Glucocorticoids (GCs) are steroid hormones released from the adrenal gland in response to stress. They are also some of the most potent anti-inflammatory and immunosuppressive drugs currently in clinical use. They exert most of their physiological and pharmacological actions through the classical/genomic pathway. However, they also have rapid/non-g...
Article
Full-text available
Inkjet printing technology was used to apply insulin polymeric layers on metal microneedles for transdermal delivery. A range of various polymers such as gelatin (GLN), polyvinyl caprolactame-polyvinyl acetate-polyethylene glycol (SOL), poly(2-ethyl-2-oxazoline) (POX) and trehalose (THL) were assessed for their capacity to form thin uniform and hom...
Article
Full-text available
Hematopoietic stem cells (HSCs) maintain balanced blood cell production in a process called hematopoiesis. As humans age, their HSCs acquire mutations that allow some HSCs to disproportionately contribute to normal blood production. This process, known as age‐related clonal hematopoiesis, predisposes certain individuals to cancer, cardiovascular an...
Article
Full-text available
Polydopamine has been found to be a biocompatible polymer capable of supporting cell growth and attachment, and to have antibacterial and antifouling properties. Together with its ease of manufacture and application, it ought to make an ideal biomaterial and function well as a coating for implants. In this paper, atomic force microscope was used to...
Article
Full-text available
Purpose: The present study reports a novel conjugate of gemcitabine (GEM) with bovine serum albumin (BSA) and thereof nanoparticles (GEM-BSA NPs) to potentiate the therapeutic efficacy by altering physicochemical properties, improving cellular uptake and stability of GEM. Methods: The synthesized GEM-BSA conjugate was extensively characterized b...
Article
The present study reports a novel conjugate of gemcitabine (GEM) with bovine serum albumin (BSA) and thereof nanoparticles (GEM-BSA NPs) to potentiate the therapeutic efficacy by altering the physicochemical properties, improving the cellular uptake and stability of GEM. The GEM-BSA conjugate was synthesized by carbodiimide chemistry and confirmed...
Article
Full-text available
Formation of ordered porous polymer films is one of the techniques currently under investigation for its potential for the manufacturing of coatings with biomedical applications. Aiming for films with improved characteristics against bacterial colonization, poly(methyl methacrylate) (PMMA) and polyurethane (PU) films were formed via the spin coatin...
Article
Using a combination of experimental and computational approaches, the interaction between anastellin, a recombinant fragment of fibronectin, and representative biomaterial surfaces has been examined. Anastellin and superfibronectin, have been seen to exhibit anti-angiogenic properties and other properties that may make it suitable for consideration...
Article
Inkjet printing technology was used to apply insulin polymeric layers on metal microneedles for transdermal delivery. A range of various polymers such as gelatin (GLN), polyvinyl caprolactame-polyvinyl acetate-polyethylene glycol (SOL), poly(2-ethyl-2-oxazoline) (POX) and trehalose (THL) were assessed for their capacity to form thin uniform and hom...
Conference Paper
Full-text available
Glucocorticoids (GCs) are steroid hormones released from the adrenal gland in response to both physical and emotional stress. They are also released during strenuous exercise and are the only drugs that have been shown to improve skeletal muscle strength and function as well as delay the onset of disability in suffers of Duchenne muscular dystrophy...

Network

Cited By