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David  Andrew Ross Burd

David Andrew Ross Burd
Free Lance Medico/Legal Consultant · Second Opinion (Medico/Legal) Hong International Ltd Kong

MB ChB, FRCSEd, MD, PhD

About

213
Publications
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Introduction
David Andrew Ross Burd currently works at the Second Opinion (Medico/Legal) Hong International Ltd Kong, Free Lance Medico/Legal Consultant. David Andrew Ross does research in Epidemiology, Surgery and Plastic Surgery. Their current project is 'It is complicated. I am just thinking at present.'.

Publications

Publications (213)
Article
Full-text available
Wound management is most important and challenging job in medical field.as we know there are regulatory guidelines for wound management .wound has two major type's acute and chronic .acute wound subdivided into post-operative wound, abrasion, contusion, superficial burn which heal with conventional line of treatment. We are concerned about non heal...
Chapter
For this Chapter in this Book the story of the journey towards scarless healing should begin with the birth of Ian Donald on the 27th of December, 1910. He was born in Liskeard, an old market town located on the southern edge of Bodmin Moor in South West England. The First World War was just around the corner and within the span of one generation t...
Article
Full-text available
Introduction: This case report aims to raise awareness of the unique protocol developed in the Prince of Wales Hospital (PWH) in Hong Kong, for the acute management of acid assault burns. Chemical assaults are rare in the UK, although, previously there have been several high-profile cases in the past three decades. In Hong Kong, acid assaults are m...
Article
Our previous study has demonstrated the stem cell-like properties of human umbilical cord lining epithelial cells (CLECs) and their capability for epidermal reconstitution in organotypic skin culture; however, the immunogenicity of these cells has not been clearly defined. We assessed several aspects of the immune properties of CLECs in vitro. We e...
Article
Preliminary clinical trials suggest a superior effect when steroids and 5-fluorouracil are injected together for the intralesional therapy of keloids. In addition, it has been proposed that low-dose 5-fluorouracil may have advantages over conventional high dosages. We explored the molecular basis for the potential synergy involved in the combined t...
Article
Objective: To review clinical characteristics, imaging modalities, and treatment outcomes of patients referred to a multidisciplinary clinic for management of vascular malformations. Design: Retrospective case series. Setting: Multidisciplinary vascular malformation out-patient referral clinic in a teaching hospital in Hong Kong. Patients: T...
Patent
Full-text available
Disclosed are a hydrogel dressing for covering or treating a wound and a method for preparing the same. The hydrogel dressing includes a matrix structure of a cross-linked mixture, and an elastic sheet coated with an elementary metal or ionic metal embodied in the matrix structure. The mixture comprises a hydrophilic polymer, about 0.5 to about 5 w...
Article
Full-text available
This case report aims to raise awareness of the unique protocol developed in the Prince of Wales Hospital (PWH) in Hong Kong, for the acute management of acid assault burns. Chemical assaults are rare in the UK, although, previously there have been several high-profile cases in the past three decades. In Hong Kong, acid assaults are more common, an...
Article
Full-text available
Advanced wound care centres are now a well established response to the growing epidemic of chronic wounds in the adult population. Is the concept transferable to children? Whilst there is not the same prevalence of chronic wounds in children there are conditions affecting the integumentary system that do have a profound effect on the quality of lif...
Article
Full-text available
The ultimate goal of the treatment of cutaneous burns and wounds is to restore the damaged skin both structurally and functionally to its original state. Recent research advances have shown the great potential of stem cells in improving the rate and quality of wound healing and regenerating the skin and its appendages. Stem cell-based therapeutic s...
Article
Full-text available
The surgical management of advanced, incurable, malignant disease presents particular ethical and technical challenges. The clear goal is palliation and the surgical futility must be avoided. This case series presents some particular challenges in end-of-life surgery. Fifteen patients referred with advanced malignant disease involving a limb girdle...
Article
The aim of our study is to review our experience in the management of patients who sustained burns associated with suicidal attempts over a 10-year period. In particular, we look into the outcome and incidence of self-harm/suicide after discharge among the survivors. Thirty-one patients with median age 36 years, ranging from 10 to 74, were included...
Article
To investigate gabapentin's role in head and neck cancer surgery following the demonstration of the effectiveness of gabapentin in reducing postoperative pain. Non-randomised open-label trial. Prince of Wales Hospital, Hong Kong. Pain scores, analgesic usage, and the frequency of adverse effects. In patients undergoing anterolateral thigh flap reco...
Chapter
The reconstruction of the human ear is a considerable challenge for the Plastic Reconstructive and Aesthetic Surgeon. This challenge is considerably increased when the need for reconstruction is due to damage following burn injury. The external ear is conceptually simple; a sandwich of skin, cartilage and skin. However the construction of the ear;...
Chapter
The United States Census Bureau estimates that in 2008 there will be 135,330,281 human births globally, which means 257 babies are born every minute. The birth of a baby is, and should be, in most cases a wonderful celebration of the process of nature. At the same time, it is an opportunity to reflect upon the complexity of human reproduction with...
Article
Full-text available
Cutaneous injury triggers a cascade of signaling events essential for wound re-epithelialization. CD9, a cell-surface protein, has been implicated in a number of cellular processes by coupling to intracellular signaling; however, its exact role in wound healing remains unidentified. We reported that CD9 was downregulated in migrating epidermis, and...
Article
Stem cells are particularly attractive for many cell-based therapeutic interventions because of their ability to self-renew and their capacity to differentiate into site-specific differentiating cells. Restoration of the integrity of epithelial continuity is an essential aspect of wound repair and tissue regeneration. We are currently looking at th...
Article
Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited blistering skin disorder caused by mutations in COL7A1 gene encoding type VII collagen, the major component of anchoring fibrils in the dermo-epidermal junction. The development of cutaneous squamous cell carcinoma (SCC) is one of the most serious complications of this disease. We re...
Article
Intralesional injection of low-dose 5-fluorouracil (5-FU) has recently been used as an experimental modality for treating keloid scarring and has shown promising efficacy in improving scar appearance and preventing recurrence of the keloid. We sought to explore the cellular- and molecular-based evidence for the observed clinical benefits. Primary c...
Article
Full-text available
There have been tremendous advances in burns care over the past 50 years. Much of this, but not all, can be attributed to basic science and clinically related research. Out of the best centres in the world, centres that are fully funded and richly resourced, best practice guidelines result in impressive outcomes not only in terms of survival but al...
Article
There have been tremendous advances in burns care over the past 50 years. Much of this, but not all, can be attributed to basic science and clinically related research. Out of the best centres in the world, centres that are fully funded and richly resourced, best practice guidelines result in impressive outcomes not only in terms of survival but al...
Article
Full-text available
Burns can cause extensive and devastating injuries of the head and neck. Prevention of the initial injury must always be a priority, but once an injury has occurred, then prevention of progression of the damage together with survival of the patient must be the immediate goals. The acute care will have a major influence on the subsequent scarring, r...
Article
Hyaluronan (HA) is a major extracellular matrix component of the skin. Amongst its biological functions is the maintenance of epidermal homeostasis. The mechanisms of action, however, remain unclear. To explore the interaction of HA with the epidermis, we have looked at the effects of exogenous application of HA in an organotypic culture model cont...
Chapter
Overview of skin injury Biomechanical considerations [1-4] Effects of friction Pressure ulcer Effects of suction Miscellaneous reactions to mechanical trauma Foreign bodies Other penetrating injuries Skin lesions in drug addicts Skin hazards of swimming and diving Vibration Reactions to internal mechanical stress Mechanical trauma and skin neoplasi...
Article
This case series comprises 31 patients who were victims of acid assault burns. They were admitted for acute or reconstructive care to a regional burns unit. Ten patients were admitted late with suboptimal acute care and needed a total of 50 reconstructive procedures. Of 13 patients admitted acutely, 7 had surgery performed after 48 hours of constan...
Article
Full-text available
We report a case of a 32-year-old woman presenting with scar endometriosis 2 years after a lower segment caesarean section. The epidemiology, pathogenesis, diagnosis, investigations and treatment of the condition are discussed. Endometriosis is a common gynaecological condition; scar endometriosis is a rare subtype and usually arises after a surgic...
Article
This case series comprises 31 patients who were victims of acid assault burns. They were admitted for acute or reconstructive care to a regional burns unit. Ten patients were admitted late with suboptimal acute care and needed a total of 50 reconstructive procedures. Of 13 patients admitted acutely, 7 had surgery performed after 48 hours of constan...
Article
Hyaluronan (HA) is a fundamental component of many biomaterials. Reports on the biological effects of HA are, however, both inconsistent and contradictory. This particularly refers to fibroblast contraction in the presence of high concentrations of HA. In this study we used a broad range of molecular weight (MW) and concentrations of HA to assay it...
Article
Full-text available
We report an unusual malignant tumour affecting an unusual site. Epithelioid haemangioendothelioma was formerly considered a tumour of intermediate malignancy but has been reclassified as fully malignant. It is important to be aware of this clinical entity as the best hope of cure is timely radical resection. There is a paucity of evidence concerni...
Article
The use of perforator-based flaps as freestyle pedicled flaps for traumatic defects has been limited. We explored this possible application in small to moderate sized traumatic defects presenting in the delayed phase, with distinct oedema and induration in the potential flap donor area and posttraumatic vessel disease. Attempts to skeletonize perfo...
Article
Aim: To describe a novel way of monitoring a buried fasciocutaneous anterolateral thigh (ALT) flap used for pharyngeal reconstruction. Methods: A tubed ALT flap was used to reconstruct a circumferential pharyngeal defect following resection of a carcinoma. An island of skin based on a separate perforator and externalized through the neck incision w...
Article
Cutaneous thermal injury caused by direct contact with objects heated solely by sun exposure is rare. We undertook to investigate factors that may influence the temperature of sun-exposed objects at the ground level. Two clinical cases of burns caused by contact with sun-exposed objects are described. Surface temperatures on a citywide scale were d...
Article
An abstract is unavailable. This article is available as HTML full text and PDF.
Article
Integra dermal regeneration template - a two-stage, tissue-engineered, artificial skin - was introduced in the UK in May 1996. There were no restrictions on clinical application and a series of applications in reconstructive surgery were undertaken. One case involved a Caucasian lady with a nose tip basal cell carcinoma (BCC) who had a single-stage...
Chapter
A significant proportion of the activities of a plastic and reconstructive surgeon is directed toward the healing of wounds and the reconstruction of defects in the skin and soft tissue. In this chapter, we look at some of the opportunities and challenges presented by the stem cells and, in particular, those derived from cord blood in the fields of...
Article
Skin is the largest immunologically competent organ in the body. The skin has two layers, epidermis and dermis. The epidermis is rich in cells that are specialized in the formation of keratin and are called keratinocytes. The epidermis consists of a stratified layer of cells stretching from the basement membrane below to the stratum corneum above....
Article
Full-text available
Article
Malignant melanoma is the world's fastest growing cancer, in terms of incidence, in the Caucasian population. There is a paucity of data regarding age-related population based studies in Chinese people. There are observations to suggest that malignant melanoma is a different disease in the Chinese with a far higher proportion of lesions being acral...
Article
I have just finished writing a short update review on cutaneous melanoma for a local journal, and a point of note is the ethnocentricity of the melanoma debate.1 2 I have no doubt that sun exposure but also …
Article
Reconstruction of defects involving the knee and proximal one third of the lower leg presents a challenging problem in plastic surgery. To evaluate the reversed anterolateral thigh adipofascial flap for covering such defects. Between September 2006 and May 2007, one man and four women with defects around the knee and upper calf underwent reconstruc...
Article
Many parents purchase topical applications without knowing what they contain, and apply them liberally to their children with dermatological disorders. In one such case, an infant developed fever, diarrhea and a small ulcer near the right labia majora which was treated with a topical cream called '999' containing dexamethasone acetate. The infant s...
Article
Full-text available
To develop burn prevention strategies for the elderly population in Hong Kong using a novel epidemiological approach. Medical records of all patients aged 60 or above who were admitted to our hospital in a 6-year period were reviewed and demographic data, injury characteristics, details of management and outcome were obtained. Selected interviews w...
Article
Extramammary Paget's disease (EMPD) is a rare disease in Chinese males. Our objectives were to examine the results of our experience, to correlate them with the published literature, and thus to formulate improved management guidelines. This was a retrospective analysis of all male patients with EMPD treated at our institution. We reviewed the pati...
Conference Paper
Full-text available
Near-infrared spectroscopy (NIRS) has been used as non-invasive sensor of blood oxygen level. In this paper, we demonstrate our implementation of a compact dual-channel blood-oxygen level monitoring system based on NIRS.
Article
A 4-mo-old Chinese infant developed necrotizing fasciitis and gangrene from a small skin infection on his buttock that was treated with topical herbs. Sequential cultures revealed a number of organisms: Enterococcus species, sensitive to ampicillin, were isolated throughout the course, and coagulasenegative staphylococci replaced gram-negative rods...
Article
Full-text available
Vaginal reconstruction after tumor resection or in congenital vaginal agenesis remains a challenging area in surgery, with many techniques previously described underlining the continued search for an ideal method. In this preliminary report, a series of patients are presented who underwent vaginal reconstruction using a deep inferior epigastric art...
Article
The prospect of being able to replace damaged tissue by the process of regeneration would dramatically and irrevocably change the impact, management and outcome of burns. The current understanding of stem cell-based modulation and therapy together with their potential developments do bring this prospect ever closer to a clinical reality. This paper...
Article
Epidermolysis bullosa dystrophica (EBD) is a rare blistering disease that may present in the neonatal period. Diagnosis is based on clinical symptomatology, histopathology, electromicroscopy and genetic studies. Age of onset, symptomatology and prognosis of the various subtypes are varied. We describe a case of EBD diagnosed in the neonatal period...
Article
Gathering information on the thermal characteristics of the causative agent in scald injuries provides clues as to the likely depth of injury. We theorize that viscosity and thermal capacity may have important roles to play when we view scalds as contact burns due to a liquid. From a 4-year review of our scald patients, we found that scalds due to...
Article
Comprehensive burn wound management comprises a challenging spectrum of acute, chronic, traumatic, and surgical wounds with a wide range of anatomical locations and depth. When processing of porcine and cadaver skin - items central to burn care management strategies - became problematic at one Hong Kong hospital, a commercially available cost-effec...
Article
Epidermolysis bullosa (EB) is one of the rare blistering diseases that may present in the neonatal period. Diagnosis is based on clinical symptomatology, histopathology, electron microscopy and genetic studies. Age of onset, symptomatology and prognosis of the various subtypes are varied. We describe three cases of EB dystrophica (EBD) followed at...