Dauren Sarsenov- MD / F.E.B.S. GenSurg
- Hacettepe University
Dauren Sarsenov
- MD / F.E.B.S. GenSurg
- Hacettepe University
About
35
Publications
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379
Citations
Introduction
Current institution
Education
January 2007 - March 2013
September 1999 - June 2005
Kazakh State Medical University
Field of study
- medicine
Publications
Publications (35)
Objective: This study aimed to evaluate the differences between the types of thyroidectomy surgeries and surgical treatment approaches according to thyroid pathology results, in Turkey's two non-endemic regions.
Material and Methods: Two different centers of the country, which differ in many respects, anda re non-endemic for thyroideal diseases wer...
Objective: Hydatid cyst disease is a widespread zoonotic disease infecting humans as an intermediate host. Since the first description of this pathology, many modalities have been introduced into modern treatment protocols. Minimally invasive surgical treatment is welldescribed and widely used, but has many points where rationalization and modifica...
Objective: Today, it is recommended that the laparoscopic cholecystectomy (LC) is made with standard three ports. In this study, we aimed to determine the preoperative and intraoperative factors that require the use of an additional fourth port during three-port LC. Materials and Methods: All patients who started LC with three ports between January...
Objective:
To compare the diagnostic ability and time efficiency of contrast-enhanced (CE) whole body FDG PET/MRI protocol and non-contrast-enhanced (NCE) protocol.
Subjects and methods:
Ninety-three patients with known primary tumors underwent whole-body hybrid FDG PET/MRI during the follow-up of their malignancies with the use of NCE and CE pr...
Pancreatic hydatid cyst is a rare disease found mostly in endemic regions. Having no specific clinical signs, it may present with tension related abdominal pain, dyspepsia, a palpable mass, and signs of external pressure on the surrounding organs in accordance with localization of the lesion. Pancreatic carcinoma as a neoplastic pathology with poor...
Purpose:
The objective of this study was to assess the demographic, pathologic and survival characteristics of patients who were diagnosed as having bilateral breast cancer.
Methods:
A review was conducted of the records pertaining to patients who presented to our clinic and were diagnosed as having breast cancer. Any second cancer diagnosed wit...
Objective:
In this retrospective study, chemotherapy induced amenorrhea in patients with early stage breast cancer and its effects on survival were investigated.
Materials and methods:
Two hundred fifty-two patients received adjuvant chemotherapy without ovarian suppression treatment (OST) from 600 premenopausal patients were included in the stu...
Left ventricular assist devices (LVADs) have been implanted recently, with increasing frequency, to treat advanced heart failure with good survival rates. Since heart failure is most prevalent in patients above 70 years of age, LVAD implantations are increasing particularly in this cohort. On the other hand, due to a higher incidence of malignant t...
Objective:
The aim of this study was to investigate the impacts of personality traits, anxiety, depression and hopelessness levels on quality of life in the patients with breast cancer.
Materials and methods:
The study was performed on 90 patients diagnosed with breast cancer and 90 healthy women. Sociodemographic and Clinical Data Collection Fo...
Aim:
Tumor-infiltrating lymphocytes (TILs) have a prognostic value in breast cancer (BC); however, because of the lack of standard evaluation methods, we aimed to assess the interobserver agreement of stromal TILs (sTILs) and intratumoral TILs (iTILs) as well as the effect of hot spot areas and molecular subtyping on the overall agreement.
Method...
Objective
The aim of the present study was to investigate the possibility of the effect of life long stressful events, along with coping method used, perception of social support, and life style on the development of breast cancer.
Methods
In this hospital-based case control study, the study group comprised 250 women with breast cancer who were fo...
Objective:
The aim of this study was to determine the roles of biopsychosocial risk factors in the development of breast cancer.
Materials and methods:
This hospital-based case-control study included 491 women with breast cancer (study group) and 512 women who did not have cancer or other serious diseases (control group). Biological, psychologic...
Background:
Prolongation of survival in patients with breast cancer due to early diagnosis and modern methods of treatment has turned the attention on lymphedema, which is the most important morbidity secondary to the treatment of the disease. Determination of lymphedema and related risk factors in patients before a surgical intervention may provi...
Nowadays, surgery, radiotherapy and chemotherapy are the most frequently used modalities in the treatment of breast cancer. It is very well-known that some severe complications may result from after these treatments. Early and late complications of radiotherapy are well known. The complications of radiation therapy may be seen in (early) or after t...
Angiogenesis accompanying liver regeneration is regulated by both proangiogenic and anti-angiogenic effectors. This study investigated angiogenesis at both local and systemic levels also targeting measurement of endostatin's local expression during hepatic regeneration. Methods: 64 female rats underwent 70% hepatectomy and were sacrificed on the po...
Purpose:
The receptor status of breast cancer plays a critical role in clinical practice. During the metastatic process, a change in the biological characteristics of the tumor can be seen. This study aimed to investigate the hormone receptor and HER2 status changes between primary and recurrent breast cancers and their effect on survival.
Method...
Persistent left superior vena cava is the most common congenital venous anomaly of the thoracic venous system, occurring in 0.3% to 0.5% of individuals in the general population. It may remain asymptomatic throughout life and be incidentally found in healthy individuals undergoing vascular procedures such as venous access device placements and endo...
Secretory carcinoma is a very rare subtype of breast carcinoma. These tumors are generally associated with a favorable prognosis, although having triple-negative phenotype (estrogen receptor (ER), progesterone receptor (PR) negative and c-erbB2 (HER2) negative). In this presentation, a rare secretory carcinoma of the breast in a woman aged 24 years...
Objective:
The effect of estrogen on bone mineral density (BMD) and breast cancer has been known for a long time. The aim of this study was to compare of the BMD of patients with breast cancer and healthy individuals, and to investigate the degree of correlation of estrogen receptor (ER) with BMD.
Materials and methods:
Seventy-one patients with...
Background:
Premenopausal breast cancer with a triple-negative phenotype (TNBC) has been associated with inferior locoregional recurrence free survival (LRFS) and overall survival (OS) after breast conserving surgery (BCS). The aim of this study is to analyze the association between age, subtype, and surgical treatment on survival in young women (...
The aim of the present study was to evaluate the geographic variability of the tumor bed following oncoplastic breast-conserving surgery (OP-BCS), and to assess its relevance for radiotherapy planning. In this prospective study, pre- and postoperative computerized tomography (CT) scans of 22 patients with early-stage breast cancer were fused. The p...
A woman aged 50 years was diagnosed as having an invasive ductal carcinoma in the right breast and ductal carcinoma in situ in the left breast and underwent bilateral mastectomy eight years ago. A mass was identified during follow-up in positron-emission tomography (PET) image in the left infraclavicular region, indicating metastasis. Histopatholog...
Integrated positron-emission tomography-magnetic resonance imaging (PET-MRI) is a new hybrid simultaneous imaging modality with higher soft tissue contrast and lower radiation doses compared with PET-CT. Two patients who were referred to our hospital with left breast masses that were pathologically diagnosed as invasive ductal carcinoma. The women...
Background:
This study was aimed at investigating clinical and histopathologic features of ipsilateral breast tumor recurrences (IBTR) and their effects on survival after breast conservation therapy.
Methods:
1,400 patients who were treated between 1998 and 2007 and had breast-conserving surgery (BCS) for early breast cancer (cT1-2/N0-1/M0) were...
Background
Oncoplastic techniques enabled performing breast conserving surgery (BCS) to larger tumors. Mini latissimus dorsi flap (MLDF) is a novel approach promising successful cosmetic outcome after wide excisions for breast cancer surgery. The aims of this study are to evaluate the effect of MLDF on BCS rate in early stage breast cancer patients...
Purpose:
The correlation between imaging findings and pathologic characteristics of tumors may provide information for diagnosis and treatment of cancer. The aim of this study is to determine whether ultrasound features of breast cancer are associated with molecular subtype, histologic grade, and hormone receptor status, as well as assess the pred...
One of the most important adverse effects of zoledronic acid (ZA) is osteonecrosis of the jaw (ONJ). In previous literature, several risk factors have been identified in the development of ONJ. In this study, we aimed to determine the role of trastuzumab, an antiangiogenic agent, as an independent risk factor for the development of this serious sid...
Heterotopic pancreas is a relatively common variant of foregut embryologic dystopia that can be described as pancreatic tissue found outside the normal anatomic location, being independent from vascular supply of normal pancreas. Having all features of pancreatic tissue except for the major duct structures, this ectopic tissue may be clinically rec...
In the light of recent advances in radionuclide diagnostics of occult infectious states, it is clearly seen that positron emission tomography will have a part in routine work-up especially for critically ill patients in near future. For the purpose of further development of a specific agent that might be capable of detecting a living microorganism...
In the light of recent advances in radionuclide diagnostics of occult infectious states, it is clearly seen that positron emission tomography will have a part in routine work-up especially for critically ill patients in near future. For the purpose of further development of a specific agent that might be capable of detecting a living microorganism...
Questions
Questions (9)
There is a copper based alloy (aluminium bronze) containing iron for specific custom application. The ratios should be very unusual: 65% copper, 25% aluminium and 10% iron. I tried to search literature for this diagram, but failed to find anything. Maybe because there is no such an alloy in practical use. Software "Thermocalc" is expensive for personal use, so I tried demo version and failed to reach databases (thought that they could have this ratio alloy already) present in demo version.
Is it possible to construct a ternary phase diagram for such an alloy using some software (if yes, would you refer me to such software, or maybe even calculate it for me?)? Or somehow estimate the liquidus and solidus temperatures some other way (aside from experimental)?
Thank you very much!
Dear RG'ers,
There is a friend of mine who had a meningioma located in mid brain. Due to increase in intracranial pressure after Cyberknife treatment she had vision loss which was told to never recover. Then she had an open surgery where the tumor was 75% resected. After ventriculoperitoneal shunt she is doing actually well neurologically. Coming to vision, she was not seeing anything until postop month 2., when she started to see little shiny dots of different colors, then came lines and more complex shapes. In 5 months she started to see contours of objects and even whole picture of something in fornt of her (but only when she was somehow got scared...). Now she has constant daily change in background colour (started 3 months ago) - one day is black and she does not see anything, another day is grey and she sees contours of objects. She sees movement, she percieves brightness changes.
Do these changes mean that her vision is recovering? What does this grey-black background change mean? Is there something she can do to accelerate the process (if it is vision recovery, of course). Maybe there are neuroscientists who have seen such patients? Are there resources to get knowledge on this matter?
Thank you, guys
Best regards
I aim to suggest a reference range for some protein for rats' blood serum. Animals won't be sacrificed and can be used again and again. In ideal setting, how many animals should be used to be able to say that in, let's say 5 weeks aged rats of some certain breed line, protein X is in Y-Z range for male/female?
Thank you very much!
Can somebody advise a big, widely used and comprehensive resource on studies related to origin of life? Or maybe there are some institutions/individuals constantly working on that problem?
And another question is what happened to Eigen and Schuster's Hypercycle Theory? Is it a fundamental for today's understanding of the basic realisation of inorganic-->organic transition concept?
Does anybody know what cost would it be worth to set a totally home based laboratory for work in microbiology and dealing with cell cultures? Is it somehow possible with reasonable investment?
What happens to peptide ligands after detaching from binding site of receptor (for reversible reactions) - are they getting free and, let's say swim away or are they metabolized together with receptor itself? Found no explanation on this subject.
