Dario Tammaro

• Medical Doctor at AORN Ospedali dei Colli

Background/objectives: Giant Retroperitoneal Liposarcomas (giant RPLs) represent a rare malignant disease of adulthood that does not yet have a univocal definition in the scientific literature. The symptoms may be late, depending on the position and the size reached. The weight may exceed 20 kg, and the diameter 25 cm. The main treatment is the su...

Background Chronic pain significantly impacts quality of life and poses substantial public health challenges. Buprenorphine, a synthetic analog of thebaine, is recognized for its potential in managing moderate to severe chronic pain with fewer side effects and a lower incidence of tolerance compared to traditional opioids. Objective This retrospec...

Objective Osteoarthritis (OA) is the most common cause of chronic knee pain, often a debilitating condition that can cause a significant reduction in functional capacity. Radiofrequency is a form of neuromodulation that modulates pain signal transmission and has become progressively more common as a treatment for knee pain. This retrospective study...

Chest pain following a trans-thoracic biopsy often has multiple etiologies, especially in patients with lymphomas. Pathological neuronal mechanisms integrate with an overproduction of IL-6, TNF-α, IL1-β by macrophages and monocytes, which amplifies inflammation and pain. In consideration of this complex pathogenesis, international guidelines recomm...

Peripheral neuropathy is a frequent complication after burns. It is often associated with pain, even very intense, not very responsive to pharmacological therapies and paresthesia, allodynia, hyperalgesia. Very often the quality of life is also compromised due to the onset of psychic symptoms. Differential Target Multiplexed (DTM) Spinal Cord Stimu...

Patients with neuromuscular disease are often at risk of malnutrition. This is due to frequent dysphagia, motorimpairment, breathing difficulties and mood disorders. Malnutrition contributes to the loss of lean mass and consequently to hypotonia and worsening of muscle performance as well as contributing to micronutrient deficiency disorders. A cor...

Idiopathic Orbital Inflammatory Syndrome (IOIS) is a chronic disease characterized by the presence of flogistic and even immature osteoid tissue inside of orbita. Patients present proptosis, edema, orbital and facial pain, and redness. Proptosis usually grows with the degree of inflammation fibrosis, and mass effect. It is possible to find optic ne...

Objectives: The dorsal root ganglion (DRG) is involved in the transduction of pain signals to the central nervous system (CNS) and undergoes a number of physiopathological changes during chronic pain. The purpose of this data collection was to evaluate the long-term safety and efficacy of DRG stimulation for the treatment of chronic pain and its im...

Even patients with lymphoproliferative diseases may develop a persistent chronic pain not responsive to usual treatments due to changes in antibody production and to some treatments like radiotherapy, chemotherapy, and the administration of monoclonal antibodies, which further impair the immune defense and induce chronic inflammatory phenomena acti...

Objectives: Post-thoracotomy pain syndrome (PTPS) is defined as persistent pain following a thoracotomy and has an incidence of 21-61%. Dorsal root ganglion stimulation (DRG-S) is a form of neuromodulation that modulates pain signal transmission to the spinal cord. The aims of this study were to investigate the efficacy of DRG-S for the management...

Retrieval of central venous catheters fragments often puts us in front of different situations. Having more techniques available for strategic planning of the procedure is important. The authors propose the simultaneous use of two different approaches for the recovery of a CVC fragment from the pulmonary artery.

The use of central venous catheter (CVC) is associated with risk of catheter-related infection (CRI). They have a huge impact on healthcare costs. One of the prevention strategies of CRI is the administration of non-antibiotic lock solutions such as taurolidine. Taurolidine has been proposed as a lock therapy in CVC because of its antimicrobial eff...

Spinal Cord Stimulation is a minimally invasive, reversible therapy implemented with sophisticated techniques and implanted equipment, including different types of electrodes and pulse generators. In medical literature use of SCS to treat peripheral vascular disease since 1976 is well known. Two theories explaining the mechanisms of SCS-induced va-...

During the COVID-19 pandemic, the management of vascular access in the most critical patients was an emerging problem. Correct management of vascular access according to standards has contributed to improving the outcome especially in patients admitted to the sub-intensive units. The use of PICCs in these patients is certainly a standard of care. I...

The use of central venous catheter (CVC) is associated with risk of catheter-related infection (CRI). They have a huge impact on healthcare costs. One of the prevention strategies of CRI is the administration of non-antibiotic lock solutions such as taurolidine. Taurolidine has been proposed as a lock therapy in CVC because of its antimicrobial eff...

Thoracotomy is one of the most painful types of incision a patient can experience. Pain is a very complex pathophysiological entity. Neuronal pathophysiological mechanisms are integrated with the immunological response, which amplify inflammation and pain. Prolonged inflammation induces a pathological response of the immune-system and constantly st...

Retroperitoneal fibrosis is a connective disease of the auto-inflammatory/auto-immune type of the retroperitoneum with unknown etiology and pathological mechanism. The manifestations of the pathology can be local or systemic. Amongst the local symptoms, the dull and constant pain in the hips, back or abdomen is the most frequent. We report here a c...

INTRODUZIONE Uno degli argomenti meno noti e più controversi in algologia è rappresentato dalla gestione dei pazienti con dolore pelvico cronico. I recenti progressi tecnologici e scientifici ottenuti nella nostra disciplina hanno consentito di valutare nuovi campi di applicazione della neuromodulazione elettrica. Attualmente non vi è ancora alcun...

Introduzione Il dolore alla spalla è una delle malattie muscolo scheletriche più diffuse negli adulti con elevate percentuali di cronicizzazione (1). L'approccio terapeutico in questi pazienti deve essere multimodale con metodi non invasivi, terapie infiltrative, blocchi antalgici periferici ed infine la chirurgia. Una ulteriore possibilità di trat...

The prevalence of chronic pain is between 33% to 64% and is due to cancer pain, but it has also been observed in non-cancer patients. Chronic pain is associated with lower quality of life and higher psychological distress and depressive/anxiety disorders in patients without a history of disorder. In this study we evaluated in clinical practice the...

Introduction: The treatment of chronic intractable pain has been optimized in the years using a personalized and multimodal combination of drugs and interventional approaches. We report here our preliminary experience in Spinal Cord Stimulation with a new programming approach which simultaneously combines different waveforms and uses a new mapping...

Il dolore alla spalla rappresenta una delle affezioni algiche del sistema muscoloscheletrico che più frequentemente tende a cronicizzare; a causa della complessa struttura anatomica della spalla, tale dolore risulta spesso difficile da trattare. Le cause possono essere molteplici: patologie della cuffia dei rotatori, tendiniti, sindrome da conflitt...

Il dolore cranio-facciale rappresenta una categoria eterogenea di patologie dolorose tra le quali si annoverano la nevralgia trigeminale, il dolore facciale idiopatico persistente e la nevralgia occipitale. Tali affezioni dolorose sono generalmente poco responsive al trattamento farmacologico ed hanno delle importanti ripercussioni sulla qualità di...

Introduzione: La radiofrequenza è una corrente elettrica ad alta frequenza alternata i cui effetti terapeutici sono indicati per il trattamento di sindromi dolorose farmacoresistenti; il dolore cronico prevalentemente radicolare in assenza di indicazioni chirurgiche (ernie discali espulse o deficit neurologici gravi), è trattabile con stimolazione...

Percutaneous electrical nerve stimulation is a peripheral neuromodulation for neuropathic chronic pain. It use with a noninvasive approach, fine gauge needles inserted through the skin of the painful area providing an alternate electrical stimulation for a predetermined period of time.

Neuromodulation is a treatment modality that shows promise and so far case reports have used peripheral approaches to the trigeminal ganglion and its branches. We describe the use of high frequency spinal cord stimulation at the cervical spine as a novel approach to management of refractory trigeminal neuralgia. We have enrolled 3 patients, sufferi...

Radiofrequency neurotomy of genicular nerves has been often used as an efficacious treatment option in all patients suffering from chronic osteoarthritis pain to provide long-term pain relief. After providing informed written consent, 80 patients with severe knee chronic osteoarthritis pain had been enrolled; patients had been divided into two grou...

Objective. Radiofrequency neurotomy of genicular nerves has been often used as an efficacious treatment option in all patients suffering from chronic osteoarthritis pain of knee when intra-articular or extra-articular pharmacologic therapies have failed. The application of cold to tissues creates a conduction block, similar to the effect of local a...

Introduction: Spinal Cord Stimulation (SCS) has been widely used in the last twenty years as an efficacious treatment option when pharmacologic and mini-invasive therapies have failed in all cases of neuropathic pain. Limitations of this technique are due to extremely selected area needed to treat, as i.e. foot, lower limbs, groin, all neuronal tar...

Introduction: The “Budapest Criteria” defined CPRS type I/II as “an array of painful conditions characterized by a continuing Regional Pain seemingly disproportionate in time or degree to the usual course of any known trauma or other lesion”. Conventional Spinal Cord Stimulation (SCS) is an important treatment option (especially Type I) when less i...