Dario Di Nardo

• Doctor of Dental Surgery
• Sapienza University of Rome

Abstract Objective: To inquire the effect of glide-path (GP) preparation on reaching the working length and its influence on the cyclic fatigue and torsional stress of new Direct R MI gold files. Methods: A total of eighty Direct R MI gold files were split into two groups (n=40) according to the establishment of the GP: the GP group with the GP per...

Background This study evaluated the gingival crevicular fluid (GCF) and Peri- implant crevicular fluid (PICF) concentrations of interleukin-1 beta (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and active metalloproteinase-8 (a-MMP-8) in sites with healthy conditions vs. sites affected by periodontitis (PER) and peri-implantitis...

The aim of the current study was to retrospectively investigate the prevalence of peri-implant mucositis (PIM) and peri-implantitis (P) in a long-term follow-up (≥20 years) of implants with the same body design and body surface but different collar surfaces with laser-microtextured grooves (LMGSs) vs. no laser-microtextured grooves (no-LMGSs) in pr...

Full-arch implant-supported fixed dental prostheses, an implant-supported prosthesis, which the patient must carefully manage in home oral hygiene procedures, is the fixed alternative to a mucosal-supported or implant-anchored prosthesis. Clinically, the execution of this rehabilitation requires four implants for the lower jaw and six implants for...

Introduction. The introduction of Nickel-Titanium (NiTi) has revolutionized the f ield of endodontics. This alloy allows for easy navigation of the canal curvatures, enabling more conservative root canal preparations in a significantly reduced time. This capability stems from superelasticity, a property that enables NiTi to flex and adapt to the ca...

(1) Background: The possibility of knowing information about the anatomy in advance, in particular the arrangement of the endodontic system, is crucial for successful treatment and for avoiding complications during endodontic therapy; the aim was to find a correlation between a minimally invasive and less stressful endodontic access on Ni-Ti rotary...

This retrospective clinical study compared two different professional maintenance therapy (MT) approaches (with and without periodic removal and decontamination of prosthetic components) on peri-implant inflammatory clinical and biochemical parameters after 5 years of implant function. A retrospective analysis based on patient records was used to a...

Cement-retained implant restorations still represents a widely used prosthetic solution today, considering the simple execution, the possibility of correcting the implant axis according to the dental axis and an extremely satisfactory aesthetic. The objective of the study is to evaluate whether resin-based cements are actually more aggressive towar...

(1) Background: The overdenture is a complete denture, an implant-supported prosthesis, that the patient can remove at home for the usual oral hygiene procedures, thanks to a simple and intuitive anchoring system. Clinically, the execution of this rehabilitation for the lower arch is often favored, but when it is necessary to limit the extension of...

The aim of this retrospective study was to investigate the relationship between the amount of early bone remodeling, the marginal bone loss (MBL) progression, and the peri-implant sulcular fluid concentration of active metalloproteinase-8 (a-MMP-8) and the incidence of peri-implantitis (P) over 5 years of implant function. It has been documented th...

The aim of this study is to assess the surface alterations of four reciprocating instruments before and after the shaping of four resin-simulated root canals. The following four different reciprocating instruments are selected: 10 Reciproc Blue (RB25), 10 WaveOne Gold (WOG), 10 EdgeOne Fire (EOF) and 10 recently introduced instruments OneRECI (OR),...

The aim of this study was to explain the mechanical differences between EdgeTaper Platinum (ETP) and ProTaper Gold (PTG) determining the transition temperatures and the composition of the alloy of ETP, since no data are present in literature. A total of 130 instruments were selected: 65 ETP F2 and 65 PTG F2. 20 instruments per type were submitted t...

Aim: To compare the clinical and radiographic conditions and the expression of pro-inflammatory cytokines in peri-implant crevicular fluid (PICF) at two-piece/bone level (TP/BL) versus one-piece/tissue level (OP/TL) single implants with a laser-microgrooved collar after at least 5 years of loading. Materials and methods: In total, 20 single TP/B...

In recent years, CBCT has proved to be extremely widely used and widespread in dentistry [...]

(1) Background: BioHPP® (Bredent, UK) is a partially crystalline poly ether ether ketone (PEEK) that is strengthened using ceramic. PEEK and its various formulations represent a very interesting alternative, and has been in-depth with its literature in recent years; (2) Methods: A PubMed and Scopus search for the term “BioHPP” yielded 73 results an...

Aim: The aim of the present study was to compare the direct and indirect cytotoxicity of a porcine dried acellular dermal matrix (PDADM) versus a porcine hydrated acellular dermal matrix (PHADM) in vitro. Both are used for periodontal and peri-implant soft tissue regeneration. Materials and methods: Two standard direct cytotoxicity tests-namely,...

In recent years, improvements in imaging techniques have profoundly facilitated the diagnosis of pathologies of the maxillofacial district [...]

This preliminary study aims to evaluate the efficacy of an autologous dentin graft in preventing periodontal defects after impacted or semi-impacted lower third molars’ (M3) surgical extraction. For this purpose, radiographic and periodontal evaluation of post-extractive sockets were performed. Ten patients were enrolled in the study: twenty M3 ext...

In this report, a 26-year-old female patient experienced a facial subcutaneous emphysema, occurred in a few seconds during the surgical extraction of an impacted lower left third molar performed by the use of a high-speed turbine. The patient showed a normal mouth opening but an impossibility to fully open the left eye; there was no pain or breathi...

Background: The most used types of retention of implant-supported prostheses are screw-retained or cement-retained restorations. The advantages and disadvantages of both have been identified by various authors over the years. However, cement-retained implant crowns and fixed partial dentures are among the most used types of restorations in implant...

Since there are no reviews of the literature on this theme, the aim of this narrative review is to summarize the metallurgical tests used in endodontics, pointing out their functional use and their pros and cons and giving readers a user-friendly guide to serve as an orientation aid in the plethora of metallurgical tests. With this purpose, a liter...

Objectives: The aim of this retrospective study was to analyze peri-implant marginal bone loss levels/rates and peri-implant sulcular fluid levels/rates of metalloproteinase-8 in three timeframes (6 months post-surgery-restoration delivery (T0)-and 6 (T6) and 24 (T24)-months post-loading) and to evaluate if there is a correlation between peri-impl...

In recent years, improvements in imaging techniques have profoundly changed the diagnosis of pathologies of the maxillofacial district [...]

Since the introduction of Nickel-Titanium alloy as the material of choice for the manufacturing of endodontic rotary instruments, the success rate of the root canal therapies has been significantly increased. This success mainly arises from the properties of the Nickel-Titanium alloy: the biocompatibility, the superelasticity and the shape memory e...

(1) Background: the frequency with which diagnostic tests are prescribed with exposure to ionizing radiation, a cause of biological damage, has been studied, and with much more attention, patients are subjected to these diagnostic tests for diagnosis and follow-up. This review aimed, given the recent developments of this technology, to evaluate the...

The aim of this study was to assess the role of the crystallographic phase of Nickel-titanium (NiTi) rotary instruments in determining their torsional resistance during different bending conditions, such as different degrees and angles of curvature. 200 F-One 20.04 instruments (Fanta Dental, Shanghai, China) were used, 100 austenitic instruments an...

Objectives: to compare gingival tissue healing at surgically manipulated periodontal sites and at sites receiving implants and healing abutments with machined (MS) vs. laser-microtextured (LMS) surface placed with one-stage protocol . Material and methods: Twenty-four non smoking patients each received two implants with one-stage protocol in a s...

The purpose of this review was to analyze how the retraction and protection of lingual flap (LF+) could influence the incidence of lingual nerve injury (LNI) during third molar extraction, as compared with protocols that do not involve handling of lingual tissue (LF). A literature review was performed from the “Medline” and “Scopus” medical databas...

Previously published studies have investigated the influence of instrument access on cyclic fatigue resistance. However, no studies have evaluated the relationship between angulated access and torsional resistance. The aim of this study was to investigate the influence of the angle of access on the torsional resistance of endodontic instruments. On...

Aim: To assess the potential ability of nuclear magnetic resonance micro-imaging (mMRI) to visualize and identify soft tissue debris and unfilled spaces inside radicular canals in endodontic treated extracted teeth, for understanding the causes of treatment failure. Toward this goal, multi-parametric mMRI and cone beam computed tomography (CBCT) we...

This narrative review aims to evaluate the current evidence for the application of magnetic resonance imaging (MRI), a radiation-free diagnostic exam, in some fields of dentistry. Background: Radiographic imaging plays a significant role in current first and second level dental diagnostics and treatment planning. However, the main disadvantage is...

Introduction The aim of this study was to investigate the influence of mass and polar moment of inertia on torsional behavior of NiTi rotary instruments, to understand which parameter of cross-sectional design had a key role in terms of torsional resistance. Materials and Methods Four different instrument models were designed and meshed by a compu...

Aim: The aim of this systemic review is to investigate these parameters by analyzing the characteristics of fractured instruments to determine which is the most relevant mechanical stress that induces intracanal separation in vivo. Background: The fracture of nickel-titanium (Ni-Ti) instruments is a result of flexural fatigue and torsional fatig...

Background Repeated removal and replacement of healing abutments result in frequent injuries to the soft tissues. Purpose The purpose of this study was to evaluate the effect of disconnection/reconnection of laser microgrooved vs. machined healing and prosthetic abutments on clinical periodontal parameters, marginal bone levels, and proinflammator...

Aim and objective: The aim and objective of this study was to evaluate and compare the cutting efficacy of two different nickel titanium rotary instruments by a novel methodology: the operative torque (torque and time needed to progress toward the apex). Materials and methods: Ten fresh extracted upper first premolars with two canals were instru...

Aim and objective: The aim of this case report was to describe regenerative endodontic procedures (REPs) of the previously treated mature teeth with long-term results. Background: Regenerative endodontic procedures are aimed to treat apical periodontitis and regenerate the pulp-dentin complex in necrotic teeth. However, there is no consensus in...

Aim and objective: The aim of the present case report is to describe the digital management of an implant prosthetic rehabilitation performed by the use of different digital technologies, which allowed to successfully perform in 1 day both the surgical and the prosthetical stages with a minimally invasive approach and a high standard of care. Bac...

Objectives To retrospectively evaluate the conditions of the peri‐implant tissues in treated patients with chronic periodontitis (CP) and in patients without chronic periodontitis (noCP). Materials and Methods A chart review was used to evaluate 267 implants, 134 placed in 42 CP treated patients and 133 placed in 46 noCP patients. The primary outc...

During the long history of their evolution, higher organisms, including mammals, have learnt to take great advantage from living in close contact with selected populations of microbes.1 By living in close contact, animals and microbes underwent a progressive and mutual co-evolutive process that is believed to be a major driving force in the develop...

The aim of the present study was to retrospectively evaluate the longevity of teeth and implants during a long-term period in a cohort of periodontally compromised patients, treated and maintained in a private specialist periodontal practice, and to analyze the associated risk factors. Fifty-eight patients (30 men, 28 women) who had received active...

Abstract Aim: The aim of this systemic review is to investigate these parameters by analyzing the characteristics of fractured instruments to determine which is the most relevant mechanical stress that induces intracanal separation in vivo. Background: The fracture of nickel–titanium (Ni–Ti) instruments is a result of flexural fatigue and torsional...

The aims of the present study were to propose a new machine for testing the bending behavior of an instrument at multiple specific points along the cutting surface and to compare the influence of proprietary heat treatment on the bending ability of EdgeTaper (ET), Protaper Universal (PTU), EdgeTaper Platinum (ETP), and Protaper Gold (PTG). A total...

Introduction Previously published studies have deeply investigated the characteristics of flexural and torsional resistance of nickel-titanium rotary instruments, but none of them investigated the relationship between the 2 stresses. The objective of the present study was to evaluate the influence of flexural stresses over torsional resistance. Me...

Background: Marginal bone loss (MBL) represents an important indicator of peri-implant health and the measure of its level is considered a determining factor in the evaluation of the quality of survival. Aim of this study is to compare radiographic changes in the fractal and mesial/distal vertical dimensions of peri-implant trabecular bone of dent...

Introduction: The aim of this study was to investigate the role of the cross-sectional design surface in improving the cyclic fatigue resistance by comparing two nickel-titanium (NiTi) rotary instruments with the same heat-treatment and grinding procedure. Materials and Methods: A total of 40 new NiTi instruments (20 S-One 25.06 taper and 20 AF Blu...

Surgical extraction of the third molar can often result in the development of a periodontal pocket distal to the second molar that could delay the healing, and the socket could be colonized by bacteria and lead to secondary abscesses, or it may cause mobility or hypersensitivity. The aim of this case report is to assess the efficacy of a dentin aut...

Aim: The present study was conducted to assess the perceived risk of COVID-19 transmission in dental professionals (DPs), that include dentists and dental auxiliary staffs, and whether rapid tests should be a recommended tool to constrain the transmission of the COVID-19, and who should be bearing their cost (governments, dentists, or patients) th...

Protaper Universal (PTU), Protaper Gold (PTG) (Maillefer, Ballaigues, CH), EdgeTaper (ET), and EdgeTaper Platinum (ETP) (Albuquerque, NM, USA) were tested for both torsional and flexural resistance. The aim of the present study was to evaluate the influence of proprietary heat treatment on the metallurgical properties of the aforementioned instrume...

Aim: The aim of the present study was to take a survey on Italian practitioners concerning the perceived risks of aerosol contamination in COVID-19 times and their attitude toward modifications of treatment protocols to reduce this risk. Materials and methods: Power analysis calculated a minimum sample size of 150 participants at 99% confidence...

COVID-19 pandemic has strongly and rapidly affected routine lifestyle and consequently, dental business, practice, and education. During the pandemic period, most Governments worldwide made specific regulations or recommendations to close practices, to avoid non-urgent dental therapies and treat only dental emergencies. Some recent surveys1,2 showe...

The use of pterygoid implants can be an attractive alternative to sinus bone grafting in the treatment of posterior atrophic maxilla. This technique has not been widely used because of the difficulty of the surgical access, the presence of vital structures, and the prosthetic challenges. The use of dynamic computer aided implantology (DCAI) allows...

Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextractive alveolar healing was then assessed through...

Aim: Aim of this study is to evaluate the efficacy of two different sonic and ultrasonic devices in the elimination of debris from artificial main and accessory canals. Methodology: Two different irrigant activator devices were tested: The sonic handpiece Endo- Activator (Dentsply Maillefer, Baillagues, Switzerland) and the ultrasonic handpiece Ult...

Introduction Ultra-conservative access cavities (UCAC) have been proposed to reduce crown weakening, but there is no consensus about their design and size, about their advantages and disadvantages, which are also related on how differently they are performed. The purpose of the present study was to evaluate the possible use of a novel Dynamic Navig...

Transversal hypoplasia of the upper maxilla is a frequent condition between malocclusions. The rapid maxillary expansion (RME) is an already consolidated technique for these types of defects. This case report analyzes the outcome of a novel surgical technique that we named TOPP (Partial Palatal osteotomy technique) aiming to provide scientifically...

Aim: The aim of the present study was to investigate the role of the flat design compared with a non-flat designed instrument on the centering ability in a simulated root canal system. Materials and methods: Two file systems were chosen: the F-One (Fanta Dental, Shanghai, China) and a prototype with the same design but without the flat-side desi...

Objectives The progressive peri-implant bone remodeling caused by dynamic cycles of microdamage may change peri-implant bone characteristics and volume after the functional loading. This prospective study was designed to evaluate the radiographic trabecular bone density and peri-implant vertical dimensional changes around the non submerged dental i...

New minimally invasive endodontic cavities have been described and proposed to preserve dentin (and enamel) through strategic access, including point endodontic access cavity (PEAC). There is no consensus to what extent PEAC contributes to tooth’s resistance to fracture, because there is no agreement on how PEAC should be performed. The purpose of...

Featured Application Torque Range should be considered a crucial parameter for describing instrument safety and could ensure treatments in a more efficient way. Abstract The aim of the present study is to evaluate operative torque, torque at failure and the difference between these two values—the “torque range”—of two different NiTi files. We also...

Denture stomatitis (DS) is an inflammatory status of oral mucosae frequently observed in denture wearers, and mainly associated with oral overgrowth of Candida albicans. DS is the cause of multiple visits to the dental office and is thought to enhance the risk of systemic infections. The treatment of DS mainly relies upon improvement of oral hygien...

Background: The aim of the present study was to radiographically evaluate the vertical socket walls changes, and the peri-implant marginal bone remodelling, and clinicallly the soft tissues conditions around the non-submerged single implants placed into the inter radicular septum of mandibular molar sockets, associated with a collagen membrane, af...

Aim: The aim of this study was to analyze, by the aid of microbiological analysis and the field emission scanning electron microscopical (FE-SEM) analysis, the role of high-density polytetrafluoroethylene (d-PTFE) membranes in avoiding the microbial colonization of a nanocrystalline hydroxyapatite (nc-HA) bone graft and the involvement of this col...

The role of nickel-titanium (NiTi) in the production of endodontic instruments increased in the last few decades; therefore, the way of evaluation of its performance increased as well. Nowadays, there are several ways to evaluate NiTi instruments, divided into static and dynamic tests. The static ones are cyclic fatigue tests, torsional resistance...

Objective: To evaluate the difference in torsional resistance, angular deflection and fragment length between two new rotary instruments: AF Blue S4 and S-One. These files share all features except cross-sectional design. Material and Methods: A total of 40 new Nickel-Titanium instruments of 25 mm in length were tested in this study and divided in...

Aim: To evaluate and compare radiographic crestal bone loss (CBL) and soft tissue parameters around submerged/two-stage and nonsubmerged/one-stage single implants with the same endosseous portion (body design and surface, thread design and distance) and identical intramucosal laser-microgrooved surface, after 3 years of loading. Materials and met...

The aim of the present prospective study was to evaluate the stability of peri-implant soft tissue and the stability of the implant-gingival unit (IGU) around one-stage titanium implants with a laser-microgrooved collar surface following 3 years of loading. Thirty one-stage titanium implants with a laser-microgrooved collar surface were placed in 3...

Background: The clinical outcome of full arch fixed prostheses vs. full arch telescopic-retained retrievable prostheses supported by implants and natural tooth abutments in periodontally treated patients has been reported by few studies, with controversial results. The objective of this study was to evaluate long-term (15 years) complications of a...

Objectives This in vivo study evaluated the operative torque and preparation time of ProTaper NEXT (Dentsply Maillefer; Ballaigues, Switzerland) and EdgeFile X7 (EdgeEndo; Albuquerque, New Mexico, United States) rotary systems during root canal preparation of maxillary premolars. Materials and Methods Ten double-rooted maxillary premolars with inde...

Dynamic navigation systems were introduced to facilitate dental implantology by improving the accuracy of dental implant positioning. Dynamic navigation integrates surgical instrumentation and radiologic images by using an optical positioning device controlled by a dedicated computerized interface. These features could help in reducing the risk of...

The aim of this study was to investigate the role of the flat-designed surface in improving the resistance to cyclic fatigue by comparing heat-treated F-One (Fanta Dental, Shanghai, China) nickel–titanium (NiTi) rotary instruments and similar prototypes, differing only by the absence of the flat side. The null hypothesis was that there were no diff...

The aim of the present randomized study was to radiographically evaluate the early marginal bone remodeling (EMBR) around one-stage implants with a collar surface that is laser-microtextured (LM), placed with the mirograp/interface at different levels relative to the bone crest, and to clinically evaluate the influence of keratinized tissue thickne...

Aims: This study aims to estimate the microbial presence on the surface of different brand new NiTi endodontic instruments for clinical use. Material and methods: Eleven different types of NiTi rotary endodontic instruments, obtained from their fresh opened original packages, were assigned to three different groups, according to packaging type a...

Background: Aim of this study is to investigate the cyclic fatigue resistance of the Gold treated WaveOne Gold and the Firewire treated EdgeOne Fire instruments. The null hypotesis was that there were no differences between the lifespan of Gold treated and FireWire treated instruments when subjected to cyclic fatigue tests. Material and methods:...

Background: Aim of this study was to analyze the root canal configuration in mandibular central and lateral incisors in vivo using cone-beam computed tomography (CBCT) imaging. Material and methods: A total of 487 mandibular central incisors and 491 mandibular lateral incisors from 250 patients were examined using CBCT imaging, previously taken...

Objectives The aim of the present prospective study was to evaluate, by means of intraoral periapical radiographs and cone-beam computed tomography, hard tissue changes after ridge augmentation procedures in posterior extraction sockets with severe wall defects. Material and Methods Twenty patients, with a non-restorable premolar/molar tooth and s...

Background To evaluate the cyclic fatigue resistance of two different Nickel-Titanium instruments, Reziflow (Komet, Brasseler GmbH & Co., Lemgo, Germany) and WaveOne Gold (Dentsply Maillefer, Ballaigues, Switzerland). Material and Methods Two groups of 20 different NiTi endodontic instruments of identical tip size of 0.25 mm were tested; Reziflow...

Implant therapy has become a widespread reality in modern dentistry. Nevertheless, dental implants can fail due to different causes, among which inflammatory peri-implant diseases (IPDs) are a major challenge, with prevalences that are much higher than previously believed. Specific searches were undertaken for each question raised between October a...

Background The displacement of a third molar is a rare occurrence, but it could lead to serious and/or life threatening complication. Aim of this review is to understand the most correlated causes of displacement and the possible solutions proposed in literature to avoid and solve this complication for maxillary and mandibular third molars at the a...

Aim To clinically, biochemically, and microbiologically evaluate the influence of crown margins position on one‐stage laser‐microgrooved implants. Materials and Methods Twenty‐one‐stage titanium implants with a laser‐microgrooved collar surface, supporting screwed, single crown restorations, were placed in 20 partially edentulous patients and eval...

Aim To compare two different clinical techniques when using endodontic rotary instruments by monitoring the torque in vivo. Methodology Ten single rooted maxillary anterior teeth were prepared by an endodontist using size 25, .06 taper TF rotary instruments (KerrEndo, Orange, CA, USA). All instruments were rotated at 500 rpm with maximum torque se...