Dara S Farhadi

Dara S Farhadi
The University of Arizona | UA · College of Medicine - Phoenix

MS

About

31
Publications
1,282
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62
Citations
Education
July 2018 - May 2022
The University of Arizona, College of Medicine - Phoenix
Field of study

Publications

Publications (31)
Article
The incorporation of perspective into art and science revolutionized the study of the brain. Beginning in about 1504, Leonardo da Vinci began to model the ventricles of the brain in three dimensions. A few years later, Andreus Vesalius illustrated radically novel brain dissections. Thomas Willis’ work, Cerebri Anatome (1664), illustrated by Christo...
Article
BACKGROUND The modified Spetzler-Martin (SM) grading system proposes that grade III arteriovenous malformation (AVM) subtypes are associated with variable microsurgical risks, with small AVMs (III−) having lower risk and medium/eloquent AVMs (III+) having higher risk. Adding patient age and AVM bleeding status and compactness to the SM grade produc...
Article
Abstract Background The ideal treatment for unruptured vertebral artery dissecting aneurysms (VADAs) and ruptured dominant VADAs remains controversial. We report our experience in the management and endovascular treatment of patients with VADAs. Methods Patients treated endovascularly for intradural VADAs at a single institution from January 1, 19...
Article
BACKGROUND Interrupted and continuous suturing are 2 common techniques for microvascular anastomosis in cerebrovascular surgery. One of the technical complexities of interrupted suturing includes the risk of losing the needle in between interrupted sutures during knot tying, which may result in unnecessary movements and wasted time. OBJECTIVE To r...
Article
Large dolichoectatic aneurysms of middle cerebral artery (MCA) trifurcations are rare and often require trapping and revascularization of the region with a bypass.1-9 This video describes the treatment of an MCA trifurcation aneurysm by clip trapping and double-barrel superficial temporal artery (STA) to M2-MCA bypass followed by M2-M2 end-to-end r...
Article
Background Burst fractures of the fifth lumbar vertebra (L5) are rare injuries and typically occur because of high-energy axial compressive load. Their unique anatomy and biomechanical characteristics distinguish them from other lumbar spine injuries. To the best of our knowledge, the treatment strategies for L5 burst fractures have not been thorou...
Article
Background Multidisciplinary Spine Conferences (MSCs) are a strategy for discussing diagnostic and treatment aspects of patient care. Although they are becoming more common in hospitals, there’s a paucity of literature investigating how they impact patient care and outcomes. Objective: Examine the impact of MSCs on surgical management and outcomes...
Article
Purpose Multiple hippocampal transection (MHT) is a surgical technique that offers adequate seizure control with minimal perioperative morbidity. However, there is little evidence available to guide neurosurgeons in selecting this technique for use in appropriate patients. This systematic review analyzes patient-level data associated with MHT for i...
Article
Full-text available
Purpose To determine whether the published literature supports the current practice of utilizing antibiotics postoperatively in spine surgery. Methods A systematic review from PubMed and Cochrane Central Register of Controlled trials databases was performed. Search terms used: “Antibiotic Prophylaxis”[Mesh], antibiotic*, antibacterial*, “Spine”[Me...
Article
Full-text available
Background: Dropped head syndrome (DHS) is uncommon and involves severe weakness of neck-extensor muscles resulting in a progressive reducible cervical kyphosis. The first-line management consists of medical treatment targeted at diagnosing underlying pathologies. However, the surgical management of DHS has not been well studied. Methods: Here,...
Article
Background New findings and research regarding the microsurgical treatment of intracerebral aneurysms (IAs) continue to advance even in the era of endovascular therapies. Research in the past 2 decades has continued to revolve around the question of whether open surgery or endovascular treatment is preferable. The answer remains both complex and in...
Article
Full-text available
BACKGROUND The transradial artery (TRA) approach for neuroendovascular procedures is a safe and effective alternative to the transfemoral artery (TFA) approach. We compared the efficiency and periprocedural outcomes of TRA and TFA approaches for acute stroke interventions in patients receiving intravenous tissue plasminogen activator. METHODS A re...
Conference Paper
Objective: The uniportal transorbital approach is used in clinical practice, as has the combined transorbital transnasal, but to date, no study has assessed the surgical use and applicability of a biportal bitransorbital approach. Methods: Ten specimens underwent an anterior subfrontal (A.Sub), bilateral transorbital microscopic (BTM) and bilatera...
Article
Background: Both the pterional and supraorbital approaches have been proposed as optimal access corridors to deep and paramedian anatomy. Objective: To assess key intracranial structures accessed through the surgical approaches using the angle of attack (AOA) and the volume of surgical freedom (VSF) methodologies. Methods: Ten pterional and 10...
Article
Dorothy Russell’s contributions to neuropathology are pivotal in the evolution of modern neurosurgery. In an era preferential to men in medicine, she entered the second medical school class to include women at the London Hospital Medical College in 1919. In the laboratory of Hubert Turnbull, she met Hugh Cairns, who would become her professional ne...
Article
Various well-known people associated with the history of the presidency of the United States have experienced neurological disease or injury, especially trauma to the head or spine. Nancy Reagan, however, as the wife of President Ronald Reagan and First Lady, would leave a significant and lasting mark on the progress of neurosurgical science and ed...
Article
Objective: The incidence and severity of stroke are disproportionately greater among Black patients. In this study, the authors sought to examine clinical outcomes among Black versus White patients after mechanical thrombectomy for stroke at a single US institution. Methods: All patients who underwent mechanical thrombectomy at a single center fro...
Presentation
Introduction: Both the pterional and supraorbital approaches are standard techniques utilized by neurosurgeons on a daily basis to tackle multiple pathologies. Both approaches have been proposed as optimal access corridors to deep and paramedian anatomy purporting superiority in instrument maneuverability. Various studies have attempted to elucidat...
Article
Objective Qualitative and quantitative analyses of blood flow in normal and pathologic brain and spinal cord microvasculature wasperformedusing confocal laser endomicroscopy (CLE). Methods Blood flow in cortical, dural, and spinal cordmicrovasculature was assessed in vivo in swine. We assessed microvasculatureunder normal conditions and after vess...
Article
Full-text available
Background Noninvasive intraoperative optical biopsy that provides real-time imaging of histoarchitectural (cell resolution) features of brain tumors, especially at the margin of invasive tumors, would be of great value. To assess clinical-grade confocal laser endomicroscopy (CLE) and to prepare for its use intraoperatively in vivo , we performed a...
Article
Full-text available
This is the first study to assess confocal laser endomicroscopy (CLE) use within the transsphenoidal approach and show the feasibility of obtaining digital diagnostic biopsies of pituitary tumor tissue after intravenous fluorescein injection. We confirmed that the CLE probe reaches the tuberculum sellae through the transnasal transsphenoidal corrid...
Article
Full-text available
Understanding neuronal function at the local and circuit level requires understanding astrocyte function. We have provided a detailed analysis of astrocyte morphology and territory in the Drosophila 3rd -instar VNC where there already exists considerable understanding of the neuronal network. Astrocyte shape varies more than previously reported; ma...
Article
Full-text available
Stereotactic brain needle biopsies are indicated for deep-seated or multiple brain lesions and for patients with poor prognosis in whom the risks of resection outweigh the potential outcome benefits. The main goal of such procedures is not to improve the resection extent but to safely acquire viable tissue representative of the lesion for further c...

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