
Daphika S DkharIndian Institute of Technology BHU | BHU · School of Bio-Chemical Engineering
Daphika S Dkhar
Master of Science
PhD student in the School of Biochemical Engineering, IIT (BHU)
About
24
Publications
2,861
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
422
Citations
Introduction
Publications
Publications (24)
Cancer is considered a formidable global health threat, despite substantial strides in diagnosis, detection, and therapeutic strategies. Remarkable progress has been achieved in these realms, yet the survival rates for cancer patients have persisted at suboptimal levels over decades. Acknowledging the need to address the ongoing challenges in cance...
A monolayer of boron known as borophene has emerged as a novel and fascinating two-dimensional (2D) material with exceptional features, such as anisotropic metallic behavior and supple mechanical and optical capabilities. The engineering of smart functionalized opto-electric 2D materials is essential to obtain biosensors or biodevices of desired pe...
Picloram (4-Amino-3,5,6-trichloro pyridine-2-carboxylic acid) is a chlorinated herbicide that has been discovered to be tenacious and relatively durable in both soil and water. It is known to have adverse and unpleasant effects on humans causing several health complications. Therefore, the determination of picloram is profoundly effective because o...
To curtail pathogens or tumors, antimicrobial or antineoplastic drugs have been developed. These drugs target microbial/cancer growth and survival, thereby improving the host’s health. In attempts to evade the detrimental effects of such drugs, these cells have evolved several mechanisms over time. Some variants of the cells have developed resistan...
In vivo monitoring of essential biomolecules is crucial to address numerous critical diseases such as diabetes, cancer, and different neurological disorders that require continuous, rapid, and trace level recognition. In recent years, implantable biosensors conjugated with different kinds of nanomaterials are being used for in vivo detection as it...
Nanobiosensors are devices that utilize a very small probe and any form of electrical, optical, or magnetic technology to detect and analyze a biochemical or biological process. With an increasing population today, nanobiosensors have become the broadly used electroanalytical tools for the timely detection of many infectious (dengue, hepatitis, tub...
The focus of this research is to design a bioengineered drug delivery vehicle that is efficient in anti-cancer drug delivery in a controlled manner. The experimental work focuses on constructing a methotrexate-loaded nano lipid polymer system (MTX-NLPHS) that can transport methotrexate (MTX) in MCF-7 cell lines in a controlled manner through endocy...
A nanosensor comprising of gold nanostars (Au-Nstars)-graphitic carbon nitride (g-C3N4) nanocomposite layered on a glassy carbon electrode (GCE) to detect serotonin (ST) in various body fluids has been fabricated. The nanocomposite and the sensing platform have been thoroughly characterized with UV–visible spectroscopy (UV–vis), transmission electr...
Metallic dendrites, a class of three-dimensional nanostructured materials, have drawn a lot of interests in the recent years because of their interesting hierarchical structures and distinctive features. They are a hierarchical self-assembled array of primary, secondary, and terminal branches with a plethora of pointed ends, ridges, and edges. Thes...
In recent years, an increasing amount of attention has been paid to utilizing dedicated waste biomass as a sustainable, cheap, and abundant fuel and material source. There is a tremendous opportunity for maximizing energy production by applying different reliable waste biomass as a renewable, affordable, and excellent resource. As a result of renew...
Lab-on-a-chip (LOC) biosensors have recently piqued the interest of the research community as a result of its potential utility in personal healthcare and disease diagnostics. LOCs devices have been consistently developed over the last decades as merging microfluidics onto a single chip for performing many lab studies at the same time, such as bioc...
Cancer is one of the major health‐related issues affecting the population worldwide and subsequently accounts for the second‐largest death. Genetic and epigenetic modifications in oncogenes or tumor suppressor genes affect the regulatory systems that lead to the initiation and progression of cancer. Conventional methods, including chemotherapy/radi...
Antibodies play a crucial role in the defense mechanism countering pathogens or foreign antigens in eukaryotes. Its potential as an analytical and diagnostic tool has been exploited for over a century. It forms immunocomplexes with a specific antigen, which is the basis of immunoassays and aids in developing potent biosensors. Antibody-based sensor...
Over the past decade, compared to all other macromolecules lipid-based nanocarriers have proven to be an excellent carrier and delivery system for various pharmaceutical drugs of poor bioavailability. In addition to that, they exhibit exceptional qualities such as minimal toxicity, economical scale-up production, great biocompatibility, and high dr...
The ocean covers two‐third of our planet and has great biological heterogeneity. Marine organisms like algae, vertebrates, invertebrates, and microbes are known to provide many natural products with biological activities as well as potential sources of biomaterials for therapeutic, biomedical, biosensors, and climate stabilization. Over the years,...
Reactive oxygen species are produced as a by-product of the animal cellular metabolism and play an important function in cell signaling. Uncontrolled reactive oxygen species production is coupled with the evolution of acute diseases, namely, diabetes, cancer, tumors, cardiovascular and several neurodegenerative diseases, metabolic disorders, inflam...
Wearable devices have transformed the hourly analysis of events such as body signals and environmental risks into real‐time monitoring. Wearable sensors have facilitated the ability to obtain useful data by monitoring the physiological parameters and activities of an aided and a healthy individual. Wearable devices employ detectable biomarkers in t...
Viral infections are becoming the foremost driver of morbidity, mortality and economic loss all around the world. Treatment for diseases associated to some deadly viruses are challenging tasks, due to lack of infrastructure, finance and availability of rapid, accurate and easy-to-use detection methods or devices. The emergence of biosensors has pro...
Questions
Questions (2)
In my experiment, the peak-to-peak separation does not fall under the conventional value of 57 at 25 degree Celsius due to a temperature change. I am assuming that the reaction may be quasireversible. Can I use randles-sevcik equation for calculating the area or diffusion coefficient?
Usually, after coating the electrode surface with EDC/NHS, a decrease in the current response while performing voltametric analysis can be observed. But in my case the opposite is observed. Can anyone tell me the probable reasons for it?