Daniil Olennikov

Institute Of General And Experimental Biology, Russian Academy of Sciences · Laboratory of Biomedical Research

Dihydrosamidin (DHS), a khellactone 3′-O-isovaleroyl-4′-O-acetyl ester, is naturally found in Apiaceae plants yet remains underexplored in biomedical research. Employing HPLC-PDA -MS analysis, the profiling of coumarins in Phlojodicarpus komarovii revealed its significant presence, reaching DHS concentrations of 95 mg/g. DHS administering at a dosa...

Род Polygala Tourn. ex L. представлен в Сибири тремя видами, включая два малоизученных вида – P. hybrida DC. (син. P. comosa subsp. comosa, P. comosa var. hybrida (DC.) Petelin) и P. sibirica L., корни которых используются в восточной медицине. Хроматографическое разделение компонентов корней P. hydrida привело к выделению 21 вещества, идентифициро...

Two new isoflavone glycosides 1 and 2 were isolated from roots of Astragalus mongholicus Bunge (A. membranaceus Fisch. ex Bunge, Fabaceae). The compounds were calycosin 7-O-(2′′-O-β-D-glucopyranosyl)-β-D-glucopyranoside (astramonghoside A, 1) and calycosin 7-O-(2′′-O-β-D-glucopyranosyl-6′′-O-malonyl)-β-D-glucopyranoside (astramonghoside B, 2) accor...

Four new flavonoids, isovitexin 4′-O-(2′′′-O-β-D-glucopyranosyl)-β-D-glucopyranoside (cucumoside H), isovitexin 4′-O-(6′′′-O-β-D-glucopyranosyl)-β-D-glucopyranoside (cucumoside I), isovitexin 4′-O-(6′′′-O-βD-glucopyranosyl)-β-D-glucopyranoside-2′′-O-(6′′′′-O-p-coumaroyl)-β-D-glucopyranoside (cucumoside J), and isovitexin 4′-O-(6′′′-O-β-D-glucopyran...

The ether fraction of Artemisia scoparia Waldst. & Kit. (Asteraceae) flowers growing in eastern Siberia contained 25 flavonoids, among which was the new flavone 5,2′,4′-trihydroxy-6,7,5′-trimethoxyflavone 4′-O-acetate (arcapillin 4′-O-acetate), the structure of which was established by UV and NMR spectroscopy and mass spectrometry.

Four new cis-khellactone glycosides, which were identified as (3′S,4′S)-cis-khellactone 3′-O-β-Dgalactopyranoside (phlojosibiriside IV, 1), (3′S,4′S)-cis-khellactone 4′-O-β-D-glucopyranoside (phlojosibiriside V, 2), (3′S,4′S)-4′-O-acetyl-cis-khellactone 3′-O-β-D-glucopyranoside (phlojosibiriside VI, 3), and (3′S,4′S)-4′-O-isovaleroyl-cis-khellacton...

The water-soluble part of the EtOH extract of Rhodiola rosea L. [Sedum roseum (L.) Scop., Crassulaceae] contained 15 compounds including six new glycosides 1–6. UV and NMR spectroscopic and mass spectrometric data and chemical transformations determined the structures of the new compounds as hydroquinone 1-O-(6′-O-α-L-arabinopyranosyl)-β-D-glucopyr...

Monoamine oxidase (MAO) inhibitors are effective therapeutic agents for the treatment of neuro-degenerative diseases, and natural flavonoids found in the species Agastache belong to them. In the present study, six new acylated flavone-O-glycosides were isolated from A. foeniculum and identified using UV, NMR spectroscopy, and mass spectrometry as a...

Phenolic compounds of the genus Rhodiola (Crassulaceae) are the subject of numerous studies. Still, most data are dedicated to analyzing roots and rhizomes and, therefore, the metabolites of above-ground organs have been understudied. Rhodiola algida (Ledeb.) Fisch. & C.A. Mey. is a rare and under-investigated species of the genus growing in Altai-...

Bristled ferula (Ferulopsis hystrix (Bunge) Pimenov) is a perennial plant belonging to the Apiaceae family, and its aqueous extract is utilised in Eastern medicine to treat digestive system diseases. In this study, water-soluble polysaccharides from F. hystrix were isolated for the first time, and the basic polymer FH-3 was separated and characteri...

The Asteraceae family in Siberian Asia exhibits remarkable biodiversity and has long served as a valuable resource for domesticating various beneficial plants with medicinal, therapeutic, and industrial significance to humanity. In this work, we studied for the first time the chemical composition of six understudied or previously unexplored plant s...

New glycosides of baicalein (1–4) and wogonin (5 and 6) were found by studying phenolic compounds from roots of Scutellaria baicalensis Georgi (Lamiaceae) grown with treatment by 24-epibrassinolide. The new compounds were baicalein 7-O-(2′′-O-β-D-glucosyl)-β-D-glucuronopyranoside (scutellariside III, 1), baicalein 6-O-β-D-glucopyranoside-7-O-(2′′-O...

Seven new acylated C,O-glycosylflavones were isolated from leaves of Cucumis sativus L. (Cucurbitaceae) variety Gele Tros. The new compounds were isovitexin 4′-O-glucoside-2′′-O-(6′′′′-O-caffeyl)-glucoside (cucumoside A), isovitexin 4′-O-glucoside-2′′-O-(2′′′′-O-caffeyl)-glucoside (cucumoside B), isovitexin 4′-O-(2′′′-O-caffeyl)-glucoside-2′′-O-glu...

Dryas oxyodonta Yuz. is a perennial evergreen shrub from the Rosaceae family. D. oxyodonta thrives in subalpine and subarctic regions, as well as in highlands spanning from Central Asia to Siberia and Mongolia. Owing to a lack of information on its chemical composition, we conducted qualitative and quantitative chromatographic analyses on extracts...

The composition of phenolic compounds from Scutellaria titovii Juz. and S. catharinae Juz. (Lamiaceae) growing in Kazakhstan was studied for the first time. A total of 26 known compounds and two new O-glycosylflavones (1 and 2) were detected. The new flavonoids were elucidated as 5,7,2′-trihydroxy-6-methoxyflavone 7,2′-di-O-β-D-glucuronopyranoside...

Gentianopsis is a small gentianaceous genus with a known ethnopharmacological focus as hepatoprotectors containing two underestimated species that are scientifically unexplored: Gentianopsis komarovii (Grossh.) Toyok., which is typical of the Far East, and Gentianopsis stricta (Klotzsch) Ikonn., which is grown in Central Asia. Application of the HP...

A perennial plant Nepeta multifida L. (syn. Schizonepeta multifida (L.) Briq.) is one of the most common species of the Lamiaceae family growing in Eastern Siberia and used in traditional oriental medicine. The chemical composition of N. multifida has not been sufficiently studied. Chromatographic separation of phenolic compounds of N. multifida le...

A study of the chemical composition of polar compounds from seeds of Trigonella caerulea (L.) Ser. (Fabaceae) revealed the presence of monosaccharides (2 and 3); oligosaccharides (4–7); pinitol (8) and galactopinitols (1 and 9–11), including the new compound 1; glycosides of diosgenin (12–15); and alkaloids (16–22). Mass spectrometry, chemical tran...

Mycelium of Inonotus rheades (Pers.) Bondartsev & Singer (Hymenochaetaceae) grown with illumination by blue light contained p-hydroxybenzoic acid 4-O-glucoside, protocatechoic acid 4-O-glucoside, p-coumaric acid 4-O-glucoside, caffeic acid 4-O-glucoside, and the new styrylpyrone glycosides 1 and 2. According to UV, IR, and NMR spectroscopic and mas...

Protective effects of Leuzea uniflora (L.) Holub (Rhaponticum uniflorum (L.) DC., Asteraceae) on the white rats’ brain mitochondrial function in acute hypobaric hypoxia/reoxygenation were studied. The extract of L. uniflora in the dose of 100 mg/kg was administered to animals for 14 days. The effects of the extract on the brain mitochondria respira...

Cucumber is an important agricultural crop that is cultivated under greenhouse conditions. Cucumber cultivation generates substantial quantities of green waste that require proper disposal. The lack of data on the chemical composition of cucumber greens and their biological activity emphasizes the necessity for research on useful products resulting...

An investigation of the hexane extract of subterranean organs of Phlojodicarpus sibiricus (Fisch.) Koso-Pol. (Apiaceae) led to the isolation of 20 compounds, including four new coumarins, the structures of which were elucidated using UV, CD, and NMR spectroscopy and mass spectrometry as (3′S,4′S)-3′-O-isovaleroyl-4′-O-isobutyroyl-cis-khellactone (p...

Ferulopsis hystrix is a perennial plant of the Apiaceae family. In Buryat and Mongolian medicine, it is used as a substitute for Costus speciosus roots (ru rta), and in Tibetan medicine, it is used to cure digestive system diseases and used as a wound-healing agent. However, its metabolites and their bioactivities are still poorly understood. High-...

A study of phenolic compounds from four species of the genus Prunella (P. grandiflora, P. laciniata, P. vulgaris, and P. vulgaris subsp. asiatica) led to the isolation of 18 compounds, including the new flavonoid 1. UV and NMR spectroscopic and mass spectrometric data established that 1 was quercetin 3-O-(4′′-O-β-D-xylopyranosyl-6′′-O-α-L-rhamnopyr...

Nine compounds including two new flavonoids that were identified using UV and NMR spectroscopy and mass spectrometry as apigenin 6-C-(4-hydroxy-1-ethylbenzene)-8-C-(2′′′-O-β-D-glucopyranosyl)-β-D-glucopyranoside (cucumerin C, 1) and apigenin 6-C-(2′′′-O-β-D-glucopyranosyl)-β-D-glucopyranoside- 8-C-(4-hydroxy-1-ethylbenzene) (cucumerin D, 2) were is...

Lipid metabolism disorders are a large group of diseases for the treatment of which various strategies are used, including the use of pancreatic lipase inhibitors that reduce the intake and adsorption of lipids. This study was the first that shows that agricultural wastes of cucumber (Cucumis sativus) can be a source of the effective lipase inhibit...

Glucosidase inhibitors are essential in the treatment of diabetes mellitus. Plant-derived drugs are promising sources of new compounds with glucosidase-inhibiting ability. The Geum alep-picum Jacq. and Sibbaldianthe bifurca (L.) Kur o & T.Erikss. herbs are used in many traditional medical systems to treat diabetes. In this study, metabolites of the...

The seeds of dissected hogweed (Heracleum dissectum Ledeb., Apiaceae) are the source of hogweed oil (HSO), which is still underexplored and requires careful chemical and biological studies. The performed physico–chemical analysis of HSO elucidated basic physical characteristics and revealed the presence of fatty acids, essential oil components, pig...

Edible flowers are a new “old” trend in modern gastronomy and healthy nutrition aimed at increasing food attractiveness and improving the consumption of beneficial phytocompounds that have valuable properties. Cucumber (Cucumis sativus L., Cucurbitaceae family) is a well-known agricultural product; it is an important crop that is commonly used acro...

Two new flavonoids (1 and 2) were isolated from the extract of flowers of Rhodiola rosea L. [Sedum roseum (L.) Scop., Crassulaceae]. Their structures were established as hibiscetin 3-O-(3″-O-malonyl)-β-D-glucopyranoside-8-O-β-D-glucuronopyranoside (rhodirosin G, 1) and hibiscetin 3-O-β-D-glucopyranoside-8-O-(2″-O-malonyl)-β-D-glucuronopyranoside (r...

Alkyl cinnamates 1–8 were isolated for the first time from pollen of Pinus sylvestris L. Their structures were determined using UV, IR, and NMR spectroscopy and mass spectrometry. The known compounds 1,16-dioxohexadecan-7-yl 7-O-cis-p-coumarate (1), 1-hydroxy-16-oxohexadecan-7-yl 7-O-trans-p-coumarate (2), and 1,16-dihydroxyhexadecan-7-yl 7-O-trans...

The basic strategy for the treatment of diabetes mellitus is the control of postprandial glucose levels; therefore, pancreatic α-amylase, which hydrolyzes complex carbohydrates, is an important enzymatic target for scientific research. In the present study, an aqueous extract and its ethyl acetate fraction (EAF) from the seeds of Rhaponticum uniflo...

Two North bluebells, Mertonian stylosa and M. serrulata, are plants used in the traditional medicine of the Buryats as wound healing and antitumor remedies. Both mertensias have been used by local healers as substitutes for the rare Tibetan raw material Cynoglossum amabile. The lack of information on the chemical composition of M. stylosa and M. se...

Inonotus is a small genus of xylotrophic basidiomycetes and a source of bioactive fun-gochemicals among which a special place is occupied by polymeric compounds. In this study, polysaccharides that are widespread in Europe, Asia, and North America and a poorly understood fungal species, I. rheades (Pers.) Karst. (fox polypore), were investigated. W...

Owing to progressive aging in the population, there is an increase in patients with cogni-tive impairment. For the prevention of dementia, the use of plant remedies is relevant. Of particular interest is Klasea centauroides (L.) Cass. (Serratula centauroides L., Asteraceae), which has significant natural reserves, contains a wide range of biologica...

Lovage (Levisticum officinale W.D.J. Koch) is a known aromatic apiaceous species that is widely used as a culinary and medicinal plant. Traditionally, more scientific attention has been paid to lovage volatiles, while other groups of compounds have been underutilized. In this study, me-tabolites of fresh lovage roots were investigated by liquid chr...

Serratula L. and Klasea Cass. are two systematically related genera of the family Asteraceae, which are distributed in most of the Eurasia area and are used as food and colorants and in traditional medicines as a drug. Since 1967, 261 metabolites have been isolated and identified from five Serratula species and 21 Klasea species. This review provid...

(1) Background: Two Caucasian blueberries Vaccinium myrtillus L. and Vaccinium arctostaphylos L. are famous berry bushes growing in the Caucasus region and used to treat neurological diseases, but the chemistry and bioactivity of leaf extracts are still poorly studied. (2) Methods: Phenolic compounds of V. myrtillus and V. arctostaphylos leaf extra...

The aim of the study is to evaluate the effect of R. uniflorum dry extract on morphofunctional state of mice thymus and spleen at cyclophosphamide immunosuppression. Materials and methods . The experiments were carried out on F1 (CBAxC57Bl/6) mice 18–20 g of weight. Immune deficiency was simulated by a single intraperitoneal introduction of cycloph...

Introduction . The search, development and introduction of new drugs with an immunotropic effect are one of the priority tasks of modern immunopharmacology. Numerous studies have proven the immunotropic activity of individual substances isolated from medicinal plants (flavonoids, polysaccharides, ecdysteroids, terpenoids, etc.). In the present stud...

Marigold (Calendula), an important asteraceous genus, has a history of many centuries of therapeutic use in traditional and officinal medicines all over the world. The scientific study of Calendula metabolites was initiated at the end of the 18th century and has been successfully performed for more than a century. The result is an investigation of...

Rhaponticum uniflorum (L.) DC. (syn. Leuzea uniflora (L.) Holub) is a plant species of the Compositae (Asteraceae) family that is widely used in Asian traditional medicines in China, Siberia, and Mongolia as an anti-inflammatory and stimulant remedy. Currently, R. uniflorum is of scientific interest to chemists, biologists, and pharmacologists, and...

The chemical composition of two species in the family Boraginaceae, Nonea rossica Steven and Tournefortia sibirica L., in which alkaloids, hydroxycinnamates, and flavonoids, including two new acylglycosides 1 and 2 were observed, was studied. UV and NMR spectroscopy and mass spectrometry found that the new compounds were quercetin 3-O-(2′′-O-caffeo...

New O-glycosides of herbacetin and gossypetin (1–6) and eight known compounds were isolated from leaves of Rhodiola rosea L. [Sedum roseum (L.) Scop., Crassulaceae]. According to UV, IR, and NMR spectroscopic and mass spectrometric data, the isolated compounds were herbacetin-3-O-(3′′ -O-malonyl)-β-Dglucopyranoside-7-O-β-D-glucopyranoside-8-O-β-D-g...

BACKGROUND: The search of effective and safe drugs to prevent and treating the immune deficient states is an actual problem of modern medicine. AIM: The purpose of the study is to evaluate the effect of Serratula marginata dry extract on structure of mice thymus and spleen at cyclophosphamide immunosuppression. MATERIALS AND METHODS: The experiment...

Fragaria orientalis is the most distributed wild strawberry in the North Asia, and it is consumed in large quantities by the local population. However, poor knowledge of the chemical composition , metabolic profiles, and bioactivity leads to the insufficient use of F. orientalis beyond the region. The aim of our study was to investigate the nutriti...

Phenolic compounds of Urtica cannabina L. (cannabis nettle; family Urticaceae), a widespread Asian species of Russia, are poorly studied. In the present study, for the first time, a chromatographic analysis of U. cannabina growing in Eastern Siberia was realized together with isolation of flavonoids and hydroxycinnamates and study of the biological...

Chromatographic separation of constituents from roots and fruit of Peucedanum morisonii Besser (Apiaceae) isolated 30 compounds, including four new coumarins 1–4. UV and NMR spectroscopy and mass spectrometry established that the new compounds were officinalin isovalerate (1), umbelliferone-6-carboxylic acid 7-O-β-D-glucopyranoside (peumoriside I,...

Polysaccharide constituents from the aerial part of three species of Gentiana (Gentianaceae) growing in Azerbaijan were characterized for the first time. Neutral and acidic polymers and water-soluble polyphenol-polysaccharide conjugates containing fragments of phenolic acids and possessing antiradical activity were observed in G. asclepiadea L., G....

Lingonberry (Vaccinium vitis-idaea L.) fruits are important Ericaceous berries to include in a healthy diet of the Northern Hemisphere as a source of bioactive phenolics. The waste generated by the V. vitis-idaea processing industry is hard-skinned press cake that can be a potential source of dietary fiber and has not been studied thus far. In this...

Dracocephalum botryoides Steven and Dracocephalum austriacum L. are unexplored species of the Dracocephalum genus (Lamiaceae family) with a distribution in the Caucasus, where they are used in folk medicine and local cuisine. There are no data on the chemical composition of these Dracocephalum species. In this study, the application of a liquid chr...

The antihypoxic effect of the Nepeta multifida L. dry extract was studied in experiments on white Wistar rats. The life span of animals was determined against the background of acute hypoxias: hypercapnic, hemic, and histotoxic ones. Using the model of acute hypobaric hypoxia/reoxygenation there was evaluated the content of ATP, lactic and pyruvic...

A perennial plant Nepeta multifida L. (syn. Schizonepeta multifida (L.) Briq.) is one of the most common species of the Lamiaceae family growing in Eastern Siberia and used in traditional oriental medicine. The chemical composition of N. multifida has not been sufficiently studied. Chromatographic separation of phenolic compounds of N. multifida le...

Chromatographic separation of the Me2CO extract of Vaccinium vitis-idaea L. (Ericaceae) stems isolated new catechin-O-glycosides that were identified using UV, IR, and NMR spectroscopy and mass spectrometry as (–)-epicatechin-3-O-α-L-rhamnopyranoside (vacciniside D, 1), (+)-catechin-3-O-[4′′-O-(3′′′-hydroxy-3′′′-methylglutaroyl)]-α-L-rhamnopyranosi...

Roots of Nepeta multifida L. (Schizonepeta multifida (L.) Briq.; Lamiaceae) contained 15 observed compounds including two new rosmarinic acid glycosides 1 and 2. UV and NMR spectroscopy and mass spectrometry showed that the new compounds were rosmarinic acid 3,3′-di-O-methyl ether 4′-O-β-D-glucopyranoside (nepetamultin C, 1) and rosmarinic acid 3′-...

The new compounds vaccinisides A–C (1–3) were isolated from leaves of Vaccinium vitis-idaea (Ericaceae) and identified using chemical transformations; UV, IR, and NMR spectroscopy; and mass spectrometry as 2′ ,6′-di-O-caffeoylarbutin (1), quercetin-3-O-[2′′-O-(3′′′-hydroxy-3′′′-methylglutaroyl)]-α-L-rhamnopyranoside (2), and quercetin-3-O-[2′′-O-(3...

The paper presents the study of natural populations of Scutellaria baicalensis Georgi in the Trans-Baikal Territory and its cultivation in the Republic of Buryatia. The authors collected seed and planting material, identified thickets of wild-growing S. baicalensis, determined the phytomass in different plant communities, biological and exploitable...

The aim of the study to evaluate the anti-ischemic effect of Serratula centauroides and Rhaponticum uniflorum dry extracts for bilateral carotid artery occlusion. Materials and methods . The studies were carried out on 77 Wistar rats. Rh. uniflorum and S. centauroides dry extracts at doses 50, 100, 200 mg/kg were administered intragastrically for 1...

Comparative phytochemical and pharmacological analysis of leaves and shoots of Arctostaphylos uva-ursi (L.) Spreng. and endemic of Transcaucasia and North Caucasia Arctostaphylos caucasica Lipsch. was carried out. Phenolic compounds in methanol extracts were investigated by HPLC-PDA-ESI-MS. Pharmacological investigation was carried out at the model...

The purpose of the study is to evaluate the effect of Silene jeniseensis and Silene repens dry extracts on structure of mice thymus and spleen at cyclophosphamide immunosuppression. Materials and methods. The experiments were carried out on F1 (CBAxC57Bl/6) mice. Immune deficiency was simulated by a single intraperitoneal introduction of cyclophosp...

«BioChaga» is a natural extract of the birch mushroom chaga, produced according to the author's technology of the Irkutsk company SibPribor LLC under the trademark «Baikal Legend ». The high quality of «BioChaga» is due to the combination of environmentally friendly chaga medicinal plant raw materials rich in biologically active substances of the B...

The Parasenecio hastatus (L.) H. Koyama (Cacalia hastata L., Compositae) is a well-known medicinal plant that is widespread in Siberia and the southeast Asia and widely used in the practice of the traditional medicine of Asian countries as a wound-healing agent. The efficacy of the P. hastatus-containing medicines has been confirmed by scientific s...

In the course of the ongoing chemical study of species of Silene genus, S. repens Patrin as a common species of the genus, was selected as the object of this study. Using high-performance liquid chromatography with photodiode array detection and electrospray ionization triple quadrupole mass spectrometric detection (HPLC-PDA-ESI-tQ-MS), the presenc...

In modern life, the use of plant stress-protectors has taken on particular significance due to the wide distribution of neurosis-like and neurotic diseases caused by neuroendocrine-immune system imbalance. Special attention has been paid to the plants containing ecdysteroids, i.e., hormone-like bioactive substances with high adaptogenic activity. T...

Prickly rose (Rosa acicularis Lindl.) is the most distributed rose species in the Northern Hemisphere, used by indigenous people for various food purposes. The lack of detailed information about the chemical composition of R. acicularis has led us to study the phytochemical composition and metabolic profile of prickly rose extracts using chromatogr...

Rubus matsumuranus H. Lev. & Vaniot, a famous Siberian shrub of the Rosaceae family, is used in the folk medicine of nomads (Buryats, Yakuts, Soyots, and Mongols) as a remedy for the treatment of diseases of the respiratory and hepatobiliary systems. The lack of scientific information on R. matsumuranus leaves contributed to the investigation of th...

This work is aimed at the development of a microcolumn HPLC-UV assay for the rapid quantitative analysis of arbutin, bergenin, and gallic acid in Bergenia crassifolia. The results obtained indicate appropriate metrological parameters of the developed assay. It was found that the known methods of quantitative analysis of phenolic glycosides using SP...

The new benzofuran lignans nepetamultin A (1) and B (2) were isolated from flowers of Nepeta multifida L. [Schizonepeta multifida (L.) Briq.; Lamiaceae]. UV and NMR spectroscopic and mass spectrometric data indicated 1 was the 9′9′′′-di-O-methyl ester of schizotenuin A; 2, the 9′-O-methyl ester of schizotenuin C1. Biological studies revealed that 1...

The aim of this study was to determine effect of the styrylpyrone fraction from mycelium of hymenochaetoid species Inonotus rheades (Agaricomycetes) on ROS inhibitory effect in the cells culture of Thellungiella salsuginea under oxidative stress was examined. We identified antioxidant effect of styrylpyrones from mycelium of I. rheades on oxidative...

Willowherb (Epilobium angustifolium L., family Onagraceae) is a well-known food and medicinal plant used after fermentation as a source of beverages with high antioxidant potential. Despite this long history of use, only a few papers have described the chemical profile and bioactivity of fermented willowherb tea in general. To understand the basic...

The effect was studied of dry leaf extract of Serratula centauroides L. on the behavior of white rats (Wistar) in tests with positive reinforcement. It was revealed that the extract of S. centauroides at doses of 50200 mg/kg promotes in animals a decrease in the level of anxiety, adaptation to unfamiliar conditions, and as a consequence, to an incr...

Five new iridoid glycosides were isolated by chromatographic separation of extracts from the roots of three Gentiana species (Gentianaceae) growing in Eastern Siberia. Their structures were elucidated by spectral methods as 2′-O-(2′′-hydroxy-3′′ -O-β-D-glucopyranosyloxybenzoyl)swertiamarin (gentiridoid A), 2′-O-(2′′-hydroxy-3′′-O-β-D-glucopyranosyl...

New phenolic compounds were isolated by chromatographic separation of MeOH extracts from leaves of two Gentiana species growing in eastern Siberia. Their structures were elucidated by UV and NMR spectroscopy and mass spectrometry. The new xanthone isomangiferin-7-O-β-D-glucopyranoside (neoisomangiferin) was isolated from G. dahurica Fisch. A new C,...

Six new compounds including four flavonoids (1–3, 5) and two iridoids (4 and 6) were found in three Veronica species growing in eastern Siberia. Their structures were studied by UV and NMR spectroscopy and mass spectrometry. 6-Hydroxyluteolin-7-O-(6″-O-isoferuloyl)-β-D-glucopyranoside (veroniside A, 1) was isolated from V. daurica Steven; 6-hydroxy...

Adams’ rhododendron (Rhododendron adamsii Rehder) or Sagan Dalya tea is a famous Siberian evergreen medical plant of the Ericaceae family used in traditional medicines of Buryats, Yakuts, and Mongols as a tonic, stimulant, and adaptogenic drug. The high popularity of R. adamsii coupled with poor scientific knowledge prompted the addressing of gaps...

The present work aimed at the study of the phenolic compounds of Sanguisorba officinalis L. (Rosaceae) growing in Eastern Siberia. The quantitative content of flavonoids in S. officinalis extracts determined by the spectrophotometric method was 0.68–5.41% in herb and 0.20–0.51% in rhizomes and roots. Catechin content was 0.05–0.75% in herb and 0.08...

The authors of this study examined the seasonal changes in qualitative and quantitative contents of fatty acids, total lipids, phospholipids, and sterols of the common oat ( Avena sativa L. ) that were sown at different times. They grow in Yakutia permafrost and undergo inter-season cold hardening. During the first phase of cold hardening (fall per...