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Danielle E. Panoz-Brown

Danielle E. Panoz-Brown
Numerof & Associates Inc.

Doctor of Philosophy
Healthcare Strategy Consulting Analyst | Numerof & Associates, Inc.

About

16
Publications
1,626
Reads
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187
Citations
Citations since 2017
13 Research Items
184 Citations
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Introduction
Additional affiliations
January 2022 - present
Numerof & Associates Inc.
Position
  • Healthcare Stragety Consulting Analyst
January 2021 - January 2022
Indiana University Bloomington
Position
  • Research Associate
August 2015 - December 2020
Indiana University Bloomington
Position
  • PhD Student
Education
August 2015 - December 2020
Indiana University Bloomington
Field of study
  • Psychology | Neuroscience
August 2013 - May 2015
University of North Carolina at Wilmington
Field of study
  • Psychology | Behavior analysis

Publications

Publications (16)
Article
Vivid episodic memories in people have been characterized as the replay of multiple unique events in sequential order [1-3]. The hippocampus plays a critical role in episodic memories in both people and rodents [2, 4-6]. Although rats remember multiple unique episodes [7, 8], it is currently unknown if animals "replay" episodic memories. Therefore,...
Article
Full-text available
Vivid episodic memories in people have been characterized as the replay of unique events in sequential order [1-3]. Animal models of episodic memory have successfully documented episodic memory of a single event (e.g., [4-8]). However, a fundamental feature of episodic memory in people is that it involves multiple events, and notably, episodic memo...
Article
Chemotherapy is widely used to treat patients with systemic cancer. The efficacy of cancer therapies is frequently undermined by adverse side effects that have a negative impact on the quality of life of cancer survivors. Cancer patients who receive chemotherapy often experience chemotherapy-induced cognitive impairment across a variety of domains...
Article
The rodent odor span task (OST) uses an incrementing non-matching to sample procedure in which a series of odors is presented and selection of the session-novel odor is reinforced. An OST is frequently used to test the effects of neurobiological variables on memory capacity as the number of odors to remember increases during the course of the sessi...
Presentation
Episodic memories in people have been characterized as the vivid replay of multiple unique events in sequential order. Most animal models of episodic memory have documented episodic memory of a single event. However, a fundamental feature of episodic memory in people is that it involves multiple events, and notably, episodic memory impairments in h...
Poster
Alzheimer’s Disease (AD) is a neurodegenerative disease of aging characterized by profound impairments in episodic memory, the memory system that encodes and replays unique personal past experiences. Thus, documenting episodic memory impairment in preclinical models of AD would promote therapeutic strategies that specifically target episodic memory...
Presentation
Vivid episodic memories in people have been characterized as the replay of multiple unique events in sequential order. Although we recently showed that rats remember multiple unique events in context, it is currently unknown if animals “replay” a stream of episodic memories to remember the order in which they occurred. Therefore, we developed an an...
Article
We built upon previous work by Fujita et al. (2012, Animal Cognition, 15(6), 1055–1063) to create an experiment that investigated the presence of incidental memory for the spatial location of uneaten food in the domestic dog. Here, we dissociated potentially incidental spatial memory from the incidental memory for the characteristics of objects, in...
Article
Vivid episodic memories in people have been characterized as the replay of multiple unique events in sequential order [1, 2, 3]. The hippocampus plays a critical role in episodic memories in both people and rodents [2, 4, 5, 6]. Although rats remember multiple unique episodes [7, 8], it is currently unknown if animals “replay” episodic memories. Th...
Poster
Vivid episodic memories in people have been characterized as the replay of multiple unique events in sequential order. The hippocampus plays a critical role in episodic memories in both people and rodents. Although rats remember multiple unique episodes, it is currently unknown if animals ‘‘replay’’ episodic memories. Therefore, we developed an ani...
Poster
Full-text available
METHODS • Rats were treated with paclitaxel or its cremophor vehicle. Post treatment, episodic memory [1], prior learning, new learning, and reversal learning were assessed. • Post-treatment, markers of hippocampal neurogenesis were quantified in using BrdU and Ki67 immunostaining the dentate gyrus of the rats to examine effects of chemotherapy on...
Article
Source memory, a facet of episodic memory, is the memory of the origin of information. Whereas source memory in rats is sustained for at least a week, spatial memory degraded after approximately a day. Different forgetting functions may suggest that two memory systems (source memory and spatial memory) are dissociated. However, in previous work, th...
Poster
Episodic memory in people has been characterized as the replay of events in sequential order. We recently showed that rats remember multiple unique events and the contexts in which they occurred using episodic memory (Panoz-Brown et al., 2016. Current Biology). However, it is not known if rats remember a stream of events in sequential order using e...
Article
Full-text available
The Odor Span Task is an incrementing non-matching-to-sample procedure that permits the study of behavior under the control of multiple stimuli. Rats are exposed to a series of odor stimuli and selection of new stimuli is reinforced. Successful performance thus requires remembering which stimuli have previously been presented during a given session...
Article
The search for symmetry in nonhuman subjects has been successful in recent studies in pigeons (e.g., Urcuioli, 2008). The key to these successes has been the use of successive discrimination procedures and combined training on identity, as well as arbitrary, baseline relations. The present study was an effort to extend the findings and theoretical...

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Projects

Projects (5)
Project
Normal episodic memory function is critical in daily life. Episodic memory consists of representations of unique past events. A vast range of amnesic syndromes in humans produce prominent deficits in episodic memory. Therefore, it is imperative to understand its underlying mechanisms and neural substrate(s). Work by our lab and others suggests that elements of episodic memory can be modeled in non-human animals. These insights hold tremendous potential for translational research and may foster the development of therapeutic approaches to human diseases, such as Alzheimer's, with profound episodic memory impairments. In this continuous line of research, we use a multi-method approach to develop animal models of episodic memory.
Project
Chemotherapy is widely used to treat patients with systemic cancer. The efficacy of cancer therapies is frequently undermined by adverse side effects such as chemotherapy-induced cognitive impairment (CICI) across a variety of domains (e.g., leaning, memory, and attention) that can have a negative impact on survivors quality of life. In the current project, we seek to develop animal models of CICI by examining multiple aspects of cognitive function and dysfunction in rats treated with chemotherapeutic agents.