Daniele Naviglio

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Verified

Daniele verified their affiliation via an institutional email.

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• Master of Science
• Professor (Associate) at University of Naples Federico II

Chicken eggs represent a relevant diet source of cholesterol. With the aim of evaluating the cholesterol content of the eggs from Campania Region (Italy) and to test a new analytical procedure, a sample of 100 chicken eggs from local market was analysed by gas chromatography using a polar capillary column. The total free cholesterol was extracted f...

In this article, starting from a new solid–liquid extractive principle an innovative solid–liquid extractor is showed. Extractor Naviglio® works at room temperature and it does not need to heat the extractive system; this fact is important in the field of officinal plants and in many other cases when the objective of the extraction are the active p...

This paper presents the development of three methods for quality control, fraud detection, and authentication of butter fat and other oils/fats using chromatographic techniques, with one method for triglycerides and two methods for fatty acids (FAs). The procedure for the analysis of triglycerides requires only dissolution of the sample in í µí±›-h...

A product is characterized by low environmental impact if, during the whole process (from extraction of raw materials from solid natural matter to disposal), its negative contribution to environment modification is significantly reduced or eliminated. According to circular economy, it is important to take into consideration other aspects, such as t...

Food adulteration consists of changing the original structure of a food, and so, by its definition, it is a process not admitted by law. Adulterations can not only have commercial consequences, but also hygienic and nutritional ones, and in some cases, they can cause a serious danger to public health. Therefore, it is of great interest to understan...

Introduction A growing body of evidence recognises the role of signaling molecule of the microbiota-gut-brain axis (MGBA) in cognitive impairment (CI), but data on the link with alterations in specific cognitive domains are limited. We compared the functioning in several cognitive domains (i.e., memory, visuo-constructional, executive, and language...

Human health is now inextricably linked to lifestyle choices, which can either protect or predispose people to serious illnesses. The Mediterranean diet, characterized by the consumption of various medicinal plants and their byproducts, plays a significant role in protecting against ailments such as oxidative stress, cancer, and diabetes. To uncove...

“Aging” is a practice that allows alcoholic beverages to mature and gives them particular flavors and colors. In this context, oak or durmast wooden barrels are used in this process, thus providing different types of aging. This conventional process produces a slow enrichment of organic compounds in the spirit inside the barrels. Organic substances...

The term “officinal” derives from the Latin and includes all medicinal, aromatic and perfume plant species, which have long been a subject of interest for multiple purposes: health, food, pharmacological, cosmetic and so on. In this work, a study on six different species of medicinal plants, particularly characterized by digestive, choleretic and d...

Background Microbiota‐derived short chain fatty acids (SCFA) and liposaccharide (LPS) could modulate astrocyte and neuronal activity. Glial fibrillary acidic protein (GFAP) and neurofilament light (NfL) are markers of astroglial activation and neuronal damage, can be measured in blood samples and have been associated with Alzheimer’s disease (AD) p...

Abstract Background Increasing evidence links the gut microbiota (GM) to Alzheimer’s disease (AD) but the mechanisms through which gut bacteria influence the brain are still unclear. This study tests the hypothesis that GM and mediators of the microbiota-gut-brain axis (MGBA) are associated with the amyloid cascade in sporadic AD. Methods We includ...

SARS-CoV-2 is a new pandemic infection that affects at the beginning the upper respiratory system, and, successively, all the organisms, due to cytokine storm, with serious consequences that can reach death. The aim of this work was the observation of the nasal mucosa of enrolled 60 patients, resulting negative for two weeks to the molecular swab f...

La ricerca nel settore chimico e tecno-farmacologico ha permesso l’utilizzo di dispositivi medici a base di prodotti biologici nelle diverse fasi del processo di riparazione tessutale delle ferite acute e croniche. L’olio di neem e di iperico, l’aloe vera, gli acidi grassi essenziali vengono applicati sulla lesione solo dopo aver rimosso il tessuto...

Dengue fever is a mosquito-borne viral disease that has become a serious health issue across the globe. It is caused by a virus of the Flaviviridae family, and it comprises five different serotypes (DENV-1 to DENV-5). As there is no specific medicine or effective vaccine for controlling dengue fever, there is an urgent need to develop potential inh...

Psidium guajava L. (guava) is a small tree known for its fruit flavor that is cultivated almost around the globe in tropical areas. Its fruit is amazingly rich in antioxidants, vitamin C, potassium, and dietary fiber. In different parts of the world, this plant holds a special place with respect to fruit and nutritional items. Pharmacological resea...

Propolis is a resinous substance from beehive produced by the combination of plants and bee secretions. For a long time, this substance has gotten high attention in traditional and modern medicine. The aim of this review was to discuss the recent advances in the chemical composition and biological activities of propolis. The search for recent publi...

The aim of this work is to characterize and compare three different structures of Ferrous citrates (Fe(II)C), amorphous, semicrystalline, and crystalline incorporated into a SiO2 inorganic matrix by sol–gel technique. Fourier transform infrared spectroscopy (FTIR) confirms both the Fe(II)C presence in the silica matrix and the interactions among di...

There is no waste in nature. Everything that is produced has a purpose and everything that becomes waste can be transformed into a new resource, triggering a virtuous circuit that feeds itself. The circular economy of waste means a system in which the production‐consumption‐disposal process is overcome to replace it with a circular model, where the...

In the perspective of biosustainable development and renewable resource technologies, by‐products and waste from agro‐industrial sector represent a relatively cheap source of material suitable for several aims, which would reduce both the amount of waste and the related costs of disposal, while producing added‐value nutritional products. The proces...

Spirulina is a blue alga belonging to the class of Cyanobacteria. This alga is characterized by a high content of phycocyanin (PC), a blue photosynthetic pigment belonging to the phycobiliprotein family. As natural dye, PC has a lot of industrial applications, in several fields such as the cosmetic, food, and textile sectors. It is also used in the...

Nowadays a possible strategy in food preservation consists of the use of active and functional packaging to improve safety and ensure a longer shelf life of food products. Many studies refer to chitosan-based films because of the already-known chitosan (CH) antibacterial and antifungal activity. In this work, we developed CH-based films containing...

Abstract: Background: Non-alcoholic liver steatosis (NAS) results from an imbalance between hepatic lipid storage, disposal, and partitioning. A multifactorial diet high in fiber, monounsaturated fatty acids (MUFAs), n-6 and n-3 polyunsaturated fatty acids (PUFAs), polyphenols, and vitamins D, E, and C reduces NAS in people with type 2 diabetes (T2...

This study focused on the biological evaluation and chemical characterization of Malabaila lasiocarpa Boiss. (M. lasiocarpa) (Family: Apiaceae). The phytochemical profile, antioxidant, enzyme inhibitory of the methanolic, aqueous, dichloromethane, n‐hexane extracts were investigated. Based on UHPLC‐HRMS analyses, a total of 101 peaks were annotated...

In many cases in science, many discoveries are made by pure chance, as happened for example to Alexander Fleming (Darvel (Scotland) 6 August 1881–London (England) 11 March, 1955) who, while observing slides under a microscope in 1922, a few weeks after putting his nasal mucus on a Petri dish, noticed that cultures of microbes had developed all over...

In this work, we assess the potential of waste products of Phlegrean mandarin (Citrus reticulata Blanco), namely seeds and peel, to be reutilized as a source of bioactive compounds beneficial for the human diet. Starting from the evidence that the by-products of this specific cultivar are the most powerful sources of antioxidants compared to pulp,...

Background: Although recent data support an association between certain bacterial strains and Alzheimer's Disease (AD), it is not clear how these alterations contribute to different aspects of the disease. Increasing evidences also from our group (Cattaneo, AAIC 2020), suggest that endothelial dysfunction, reflected by the upregulation of cell adh...

Tomentosin is a natural compound known for its presence in some medicinal plants of the Asteraceae family such as Inula viscosa. Recent studies have highlighted its anticancer and anti-inflammatory properties. Its anticancer mechanisms are unique and act at different levels ranging from cellular organization to molecular transcriptional factors and...

The aim of this work was to explore a more sustainable approach in the viticulture of Mediterranean countries that could derive from growing hybrid grape varieties inheriting tolerance/resistance characters from the wild vines utilized for their selection. Among the plethora of hybrid grapes developed in the last decades, some are able to produce h...

Stryphnodendron rotundifolium Mart., popularly known as “barbatimão”, is a plant species traditionally used by topical and oral routes for the treatment of infectious and inflammatory diseases. Considering the well-described antioxidant properties of this species, this study investigated the protective effects of its keto-aqueous extract using an i...

Copper-based phytosanitary treatments are widely employed in viticulture for combating the fungal diseases of European grape (Vitis vinifera L.). Herein we evaluated copper accumulation in the soil of a 50-year-old still productive vineyard in South Italy in comparison with samples taken from a 'control' area in which grapevines had never been cult...

Cardoon (Cynara cardunculus), an herbaceous perennial plant able to grow with high productivity in dry and hot regions, as well as in unproductive soils, was used as a biomass source for the production of both bioactive compounds derived from leaves and proteins extracted from seeds. Naviglio® technology was found as an efficient method to obtain a...

In this paper a series of cases are reported to evaluate the relationship between nasal eosinophilia and rheumatoid arthritis (RA). In addition, a brief review of literature data on the correlation between eosinophilia in the respiratory system and RA was performed. Seven patients (five men and two women) aged between 7 and 60 years (mean age 38.5...

The aim of this work was to develop processing methods that safeguard the quality and antimicrobial properties of H. illucens and B. mori oils. We adopted a vegetable diet for both insects: leftover vegetables and fruit for H. illucens and mulberry leaves for B. mori. First, alternative techniques to obtain a good oil extraction yield from the drie...

The aim of this work is to synthesize Nb‐V oxide catalysts by sol gel route starting from metal alkoxides using different H2O/V ratios. Dried samples are characterized by X‐ray diffraction (XRD), atomic absorption, and Brunauer‐Emmett‐Teller (BET) analysis. Calcination of dried materials up to 600°C in flowing air has been followed with Thermogravi...

To understand the intimate essence of the phenomena that occur around us and in us, it is necessary to go down to the atomic and molecular level. From the scale of atoms to the human one, nature is chiral (the term derives from the Greek χείρ, “hand,” that are not superimposable). A chiral chemical compound exists as two isomeric forms, called enan...

The aging process of wine goes beyond conservation and involves the use of wood, which is capable of containing and protecting, and allows a limited passage of oxygen, sufficient to promote slow maturation of the wine, thanks to which it reaches the maximum of its organoleptic qualities. The most used wood is oak and during aging, the wine extracts...

Background:Metagenomic data support an association between certain bacterial strains and Alzheimer’s disease (AD), but their functional dynamics remain elusive. Objective:To investigate the association between amyloid pathology, bacterial products such as lipopolysaccharide (LPS) and short chain fatty acids (SCFAs: acetate, valerate, butyrate), inf...

Foods are a mixture of substances capable of supplying the human body with nutrients, which, once metabolized, are used mainly for the production of energy, heat, replenishment, and growth material for organs and tissues, ensuring the normal performance of vital functions necessary for growth of the human body. Therefore, the study of the chemical...

In this review we describe the relation between nasal eosinophilia and rheumatoid arthritis (RA). Moreover we was performed a literature revision that valued the relation between eosinophilia in respiratory system with arthritis. We have examined, through nasal cytology, 7 patients (5 men and 2 women) aged between 7 and 60 years old, with a middle...

In this review we describe the relation between nasal eosinophilia and rheumatoid arthritis (RA). Moreover we was performed a literature revision that valued the relation between eosinophilia in respiratory system with arthritis. We have examined, through nasal cytology, 7 patients (5 men and 2 women) aged between 7 and 60 years old, with a middle...

Microorganism resistance to conventional antibiotics represents one of the major global health concerns. This paper focuses on a peptide (OctoPartenopin) extracted from suckers of Octopus vulgaris; bioassay-guided chromatographic fractionation was used to identify this sequence, which holds significant antibacterial activity against Gram-positive a...

Peel, pulp and seed extracts of three mandarin varieties, namely Phlegraean mandarin (Citrus reticulata), Kumquat (Citrus japonica), and Clementine (Citrus clementina) were compared and characterised in terms of photosynthetic pigment content, total polyphenols amount, antioxidant activity and vitamin C to assess the amount of functional compounds...

Featured Application: In this study two extraction methods for Ganoderma lucidum spores were evaluated for the potential use of extracted compounds in cancer treatments. Our findings showed that the innovative Rapid Solid Liquid Dynamic Extraction (RSLDE) permits the successful extraction of compounds with antiproliferative activity against human c...

Featured Application: This study sought to contribute to the improvement of the extraction, identification and quantification of the fatty acids component in Ganoderma lucidum spores in order to find simple and non-expensive tools for laboratory studies aiming at future applications, such as the easy comparison of lipids produced by different strai...

In recent years, the concept of food has undergone a radical transformation to the point of attributing to foods, in addition to their nutritional and sensorial properties, an important role in maintaining health and psycho-physical well-being and in the prevention of certain diseases. However, foods can hide many pitfalls for human health. There a...

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Comparison between RSLDE and maceration applied to alcholic extraction of FENUGREC GRAINES AND VANILLE GOUSSES SUSTAINABLE

Comparison between RSLDE and maceration applied to alcholic extraction of FENUGREC GRAINES AND VANILLE GOUSSES SUSTAINABLE

In this work, the effect of dyes extracted through the Naviglio method (an eco-innovative solid-liquid extraction technique) was tested, which proved interesting for such an extraction. The dyes extracted from Opuntia ficus-indica (L.) Miller waste were treated to maximize the extraction of the coloring molecules. The extraction method was compared...

In the present work, the kinetics of the extraction process from female inflorescences of Canapa sativa subsp. sativa var. sativa were studied, on the basis of determination of the content of cannabinoids: cannabidiolic acid (CBDA), Δ9-tetrahydrocannabinolic acid (THCA), cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), before and after decarbox...

In the present work, the kinetics of the extraction process from female inflorescences of Canapa sativa subsp. sativa var. sativa were studied, on the basis of determination of the content of cannabinoids: cannabidiolic acid (CBDA), Δ9-tetrahydrocannabinolic acid (THCA), cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), before and after decarbox...

In the course of investigations on the role of secondary metabolites in plant-microbe interactions, the production of secondary metabolites by Macrophomina phaseolina isolates from Eucalyptus globulus, was studied. This fungus is responsible for several plant diseases which affect crop productivity and industry. Although secondary metabolites may p...

Iron is an essential trace element for animals, in fact the human body is not able to produce iron independently and for this reason it must be obtained by dietary intake. Generally, with proper nutrition and intact intestinal flora, the required dose of iron can be taken through food. However, in case of deficiency, it is necessary to resort to th...

An ideal drug delivery system is developed to provide the therapeutic amount of a drug at the appropriate site in the body and to maintain the desired drug concentration. Interactions between drugs and the sol–gel system can affect the rate of release. The aim of this work is the synthesis of iron(II)‐based therapeutic systems. The use of oral iron...

The aim of this work is the development of a system able to release ferrous ions in a controlled manner. An interesting alternative to a systemic therapy can be the use of controlled drug release for medical applications. Starting from iron powder and citric acid, ferrous citrate (Fe(II)C) is synthesized by a redox reaction between these two. The c...

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Nasal polyposis is characterized by benign, non-cancerous and painless growths originating in the tissue of the nasal cavities and paranasal sinuses. Polyps arise from chronic inflammation due to asthma, recurrent infections, allergies, drug sensitivity or immune disorders. They can obstruct the nasal cavities and thus cause respiratory problems, a...

Sea urchins (Echinodermata, Echinoidea) are good a source of bioactive compounds belonging to different classes of natural substances. The edible Mediterranean sea urchin Paracentrotus lividus is a renowned animal model for study in different fields of biology, but it is intensively harvested for high commercial value due to the delicacy of its gon...

It is taken for granted that paper filters (inert cellulose filters) do not affect water. However, our experiments show that after such filters repeatedly touched water, the liquid is modified. For example, the liquid’s electric conductivity, density, structure and composition are modified. The modifications neither are ascribable to impurities pre...

Lycopene is a red carotenoid pigment found in fresh tomatoes. Several epidemiological studies show that the lycopene content of tomatoes and tomato-based products is related to a variety of health benefits due to its antioxidant activity, which is fundamental in treating cardiovascular diseases, slowing down cellular ageing and preventing some form...

Traditionally, solid-liquid extractions are performed using organic and/or inorganic liquids and their mixtures as extractant solvents in contact with an insoluble solid matrix (e.g., the Soxhlet method) or using sequential atmospheric pressure systems that require long procedures, such as maceration or percolation. The objective of this procedure...

[This corrects the article DOI: 10.1016/j.heliyon.2019.e01526.].

Lasiodiplodia theobromae is a fungal plant pathogen that has been associated with Botryosphaeria dieback of grapevine. Despite several studies on L. theobromae, until now the production of secondary metabolites by strains isolated from grapevines has not been reported. The ability of two strains of L. theobromae isolated from grapevine to produce l...

In the current era of high consumption and increasing waste, many products that are believed to be unusable can find a new purpose in the market. For example, the grape peel waste resulting from the production of wine contains numerous bioactive compounds. In reality, grape peels are by-products of winemaking that can be conveniently reused in many...

These data demonstred the high efficiency of Extractor Naviglio compared with conventional maceration of Fenugreeek and Vanilla. Kinetics of extraction of the two techniques is very different.

This chapter aims to explore the classifications, origins, and characteristics of natural beverages. Beverages are liquids suitable for human consumption, and the beverage of excellence is definitively water, as this substance is more essential for life than food. Natural beverages for human consumption are divided into two main categories: (1) alc...

There is evidence that secondary metabolites are involved in the fungal pathogenicity and virulence of Neofusicoccum spp. Fatty acids may also influence the plant–pathogen interaction but, so far, no information is available on their production by species of Neofusicoccum associated with Botryosphaeria dieback, which is a well-known syndrome of sev...

Background & aims: Dietary polyphenols have beneficial effects on glucose/lipid metabolism in subjects at high risk to develop type 2 diabetes; however, the underlying mechanisms are not clear. We aimed to evaluate: 1) the acute effects of the consumption of a drink rich in polyphenols from red grape pomace (RGPD) on glucose/insulin and triglyceri...

The use of oral iron integration is commonly recommended for the treatment of iron deficiency, nevertheless the diagnosis and treatment of this disease could clearly be improved. The aim of this work was the synthesis of therapeutic systems, iron (II) based, by sol-gel method. In an SiO2 matrix, we embedded different weight percentages of polyethyl...

Iron deficiency represents a widespread problem for a large part of the population, especially for women, and has received increasing attention in food/supplement research. The contraindications of the iron supplements commercially available (e.g., imbalances in the levels of other essential nutrients, low bioavailability, etc.) led us to search fo...

The renewed interest in medicinal and aromatic plants and the increase in their market demand have favoured rural development programs for their cultivation, also as a measure to counteract the profound crisis affecting some agricultural sectors. Sage (Salvia officinalis) is a plant of the Lamiaceae family, whose leaves contain some different activ...

Ultrasound is composed of mechanical sound waves that originate from molecular movements that oscillate in a propagation medium. The waves have a very high frequency, equal to approximately 20 kHz, are divided into two categories (i.e., low-intensity and high-intensity waves) and cannot be perceived by the human ear. Nature has created the first ul...

Pasta with eggs added (generally termed “special pasta” for Italian legislation) is made by adding no less than 4 eggs without shells (or no less than 200 g of liquid or lyophilized egg product) per kilogram of semolina, as provided by law. In this work, to determine the final content of eggs added to dough, an analytical procedure was developed fo...

In the last decades the increasing awareness by the scientific community of the importance to exploit natural resources for the finding of new bioactive products has stimulated a huge research activity concerning the marine biological resources, and advanced strategies have been developed for investigations on microbial metabolomics. Gas chromatogr...

Lasiodiplodia theobromae is a phytopathogenic fungus that causes diseases not only in a broad number of plant hosts but also occasionally in humans. The capacity of L. theobromae to produce bioactive metabolites at 25 C (environmental mean temperature) and at 37 C (body mean temperature) was investigated. Two strains, CAA019 and CBS339.90, isolated...

Stevia rebaudiana Bertoni is a perennial shrub belonging to the Asteraceae family. The leaves contain a mixture of steviol glycosides with extraordinary sweetening properties, among which the most important are stevioside and rebaudioside A. These components have a high sweetening power, which is about 300 times that of sucrose, and a negligible ca...

This research aimed to determine the effects of cryo-maceration at different temperatures on polyphenol content during the winemaking process of Chardonnay wine. Samples of Chardonnay grapes were subjected to rapid cooling processes by direct injection of liquid CO2 to obtain final temperatures of 10.0, 8.0, 6.0 and 4.0 °C and yield different batch...

The authors describe a case of Epstein Barr virus infection (EBV) in a five-year-old girl. In the field of otorhinolaryngology diagnostics, and in the strong suspicion of a viral disease, the study of the nasal mucosa has highlighted the presence of atipical lymphocyte cells. This observation led the authors to anti-EBV antibody research and a bloo...

Talarodiolide, a new 12-membered macrodiolide, was isolated and characterized from the culture filtrate of strain LT6 of Talaromyces pinophilus. The structure of (Z)-4,10-dimethyl-1,7-dioxa-cyclododeca-3,9-diene-2,8-dione was assigned essentially based on NMR and MS data. Furthermore, several known compounds were isolated and identified in the crud...

French fries are popular products worldwide. However, this product is a sufferable source of high acrylamide due to high temperature and low moisture. The main objective of this study was to evaluate the effect of grass pea flour (GPF), transglutaminase (TGase)-treated (GPF + TGase), chitosan (CH), and pectin (PEC) hydrocolloid coating solutions on...

Imbalance of the iron level in the body causes several diseases. In particular, the low level of iron, during pregnancy, is responsible for the iron deficiency anemia, and even of neurodegenerative diseases. Although the treatment of iron deficiency anemia with oral iron supplements has been known, this problem still afflicts many people. The aim o...

Objectives Gastroesophageal reflux disease (GERD) or Gastro-Oesophageal Reflux Disease (GORD), is a disease of interest in gastroenterology that is caused by pathological complications of gastroesophageal reflux (GER). This study aims to assess the ability of reduced-carbohydrate diets and foods enriched with acid pH (lemon and tomato) to quickly a...

Il chitosano è un polimero naturale ottenuto per deacetilazione della chitina, principale componente dell’esoscheletro degli insetti, dei gusci dei crostacei, della parete cellulare dei funghi. La possibilità di ottenere, mediante elettrospinning, elettrofilati di chitosano a diverso spessore ha indicato la strada per le varie applicazioni del chit...

Portulaca oleracea is a wild plant pest of orchards and gardens, but is also an edible vegetable rich in beneficial nutrients. It possesses many antioxidant properties due to the high content of vitamins, minerals, omega-3 essential fatty acids and other healthful compounds; therefore, the intake of purslane and/or its bioactive compounds could hel...

Stevioside and rebaudioside A are the main diterpene glycosides present in the leaves of the Stevia rebaudiana plant, which is used in the production of foods and low-calorie beverages. The difficulties associated with their extraction and purification are currently a problem for the food processing industries. The objective of this study was to de...

In this work, a comparison between three extraction processes, including traditional maceration in n-hexane and ethyl alcohol, supercritical fluid extraction (SFE) and cyclically pressurized extraction known as rapid solid-liquid dynamic extraction (RSLDE), has been carried out for the extraction of pyrethrins, predominantly nonpolar natural compou...

Chitosan is the most common natural polymer after natural cellulose. It is obtained by deacetylating chitin and has many versatile uses because of its solubility in weak acids; it can be used to produce biodegradable adhesive films, fibers of different thicknesses obtained by means of electrospinning, functional hydrogels, nanoemulsions and nanopar...

A set of seven extraction experiments was performed to investigate the influence of pressure cycles on the kinetics of solute removal from leaves of mate dispersed in water. The mass ratio of liquid to dry solid (40), the temperature (32°C) and time of extraction (3600 s) were not varied. Five extraction runs were under cyclic pressurization (1 cyc...