Daniela Beghelli

Daniela Beghelli
University of Camerino | UNICAM · School of Biosciences and Veterinary Medicine

About

53
Publications
23,976
Reads
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989
Citations
Citations since 2016
25 Research Items
749 Citations
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
Additional affiliations
August 1993 - present
University of Camerino
Position
  • Senior Researcher
August 1993 - March 2017
University of Camerino
Position
  • Senior Researcher

Publications

Publications (53)
Article
Full-text available
Nutrition has relevant consequences for human health and increasing pieces of evidence indicate that medicinal mushrooms have several beneficial effects. One of the main issues in Western countries is represented by the challenges of aging and age-related diseases, such as neurodegenerative disorders. Among these, Parkinson’s disease (PD) affects 1...
Article
This study investigated the effects of dietary linseed and physiological state on blood concentrations of some metabolic hormones and indicators, in transition dairy ewes. From 21 d before lambing to 60 d post-partum, ewes were provided with one of three isoenergetic and iso‑nitrogenous pelleted concentrates, without (CTR, n = 21), or with 100 (EL-...
Article
Full-text available
Aging is a multifactorial phenomenon characterized by degenerative processes closely connected to oxidative damage and chronic inflammation. Recently, many studies have shown that natural bioactive compounds are useful in delaying the aging process. In this work, we studied the effects of an in vivo supplementation of the stilbenoid pterostilbene o...
Article
Full-text available
Spent coffee grounds (SCGs), waste products of coffee beverage production, are rich in organic compounds such as phenols. Different studies have demonstrated phenol beneficial effects in counteracting neurodegenerative diseases. These diseases are associated with oxidative stress and neuroinflammation, which initiates the degeneration of neurons by...
Article
Full-text available
Neurodegenerative diseases are driven by several mechanisms such as inflammation, abnormal protein aggregation, excitotoxicity, mitochondrial dysfunction and oxidative stress. So far, no therapeutic strategies are available for neurodegenerative diseases and in recent years the research is focusing on bioactive molecules present in food. In particu...
Article
Objectives: To determine the draft genome sequence and analyze the genetic features of a Staphylococcus pseudintermedius clinical isolate according to the main typing schemes available with a special focus on antibiotic resistance. Methods: The strain was isolated from a case of otitis externa in a dog. Its identity and pattern of antibiotic sus...
Article
Full-text available
Aging and age-related neurodegeneration are among the major challenges in modern medicine because of the progressive increase in the number of elderly in the world population. Nutrition, which has important longterm consequences for health, is an important way to prevent diseases and achieve healthy aging. The beneficial effects of Vigna unguiculat...
Article
Full-text available
Allium subhirsutum, known as hairy garlic, is a bulbous plant widespread in the Mediterranean area and locally used as a food and spice. In the present study, the chemical profile of the ethanolic extracts from bulbs (BE) and aerial parts (APE) were analyzed by HPLC-ESI-MSn, and antioxidant properties were evaluated by DPPH, ABTS and TEAC assays. T...
Article
This study was carried out to characterize extracts from nine samples of the apple ‘Mela Rosa dei Monti Sibillini’ (MR) and to assess the antioxidant and anti-inflammatory activities. The extracts were analysed by High Performance Liquid Chromatography coupled with photodiode array detector and mass spectrometry (HPLC-DAD-MS) for 20 phytochemicals....
Article
Full-text available
The effects of an oregano and/or rosemary (Origanum vulgare L. and/or Rosmarinus officinalis L.) dietary supplementation to the diet of fattening pigs were investigated. Thirty-two grower-finisher pigs (45 kg) were divided into four dietary groups identified as: control diet (CTR); CTR+ 0.2% oregano (O); CTR + 0.2% rosemary(R), and CTR+ 0.1% oregan...
Article
Pulicaria undulata is used as a traditional herbal remedy in Egypt. We used gas chromatography-mass spectrometry for analysis of essential oil of this plant growing wild in Egypt and 64 compounds were identified. The oil was rich in oxygenated monoterpenes (64.0%) and aromatic derivatives (18.8%). The major components were carvacrol (46.5%), xantho...
Article
In the present study the use of Selenium-fortified olive leaves as potential dietary source of Se in rabbit nutrition was evaluated. Sixty New Zealand White rabbits (35 days of age) were randomly assigned to the following dietary treatments: standard diet (C), and C supplemented with either 10% olive leaves (OL) or 10% Selenium-fortified olive leav...
Article
Full-text available
Phytotherapy, herbal remedies and dietary supplementation are recovering, to the present day, more and more attention from the scientific world of the Western countries not only in virtue of the antibiotic-resistance emerging problem or of the hypersensitivity towards some synthetic molecules typical of the conventional medicine, but also because t...
Article
Full-text available
Diabetes mellitus (DM) is a common disorder in middle-aged to older dogs. Treatment options, similar to those for humans, include insulin injection, dietary changes and exercise. Since some diabetic dogs may develop humoral immune responses to exogenous insulin resulting in treatment failure, the use of alternative medicine could represent an inter...
Article
Full-text available
Boswellia serrata (BS) is an important traditional medicinal plant that currently represents an interesting topic for pharmaceutical research since it possesses several pharmacological properties (e.g., anti-inflammatory, antimicrobial, and antitumour). The safety and versatility of this dietary supplement should allow for its use in numerous patho...
Article
Full-text available
Leishmania, an intracellular protozoan parasite, is endemic, widespread and represents a public health problem in most countries of the Mediterranean basin as it is implicated in a wide spectrum of diseases both in humans and animals. Vaccination of canines remains the best control strategy to counteract the progression of active infection for cani...
Article
The effects of a diet supplemented with oregano essential oil on performance, oxidative status, pork quality traits and sensorial properties were evaluated. In two studies, 72 pigs in indoor or outdoor conditions were assigned to either a control diet or an identical diet supplemented with 0.2% oregano essential oil. Pigs reared outdoor showed lowe...
Article
Ethnopharmacological relevance: The top flowering aerial parts of the Hypericum species are traditionally used to prepare ointments to heal cuts and burns. Sometimes even the fruits are used for these purposes. Hypericum androsaemum L., commonly known as tutsan or shrubby St. John's Wort, is a Mediterranean medicinal plant which has been traditiona...
Conference Paper
Full-text available
Lipid oxidation negatively impacts the healthfulness of meat as it causes the formation of toxic compounds like malondialdehyde and cholesterol oxidation products, which have been demonstrated to negatively affect human's health 1. For this reason, the meat industry extensively used synthetic antioxidants, especially in the past. However, in the...
Poster
Full-text available
Natural antioxidants are receiving increased attention in human and animal nutrition because of their association with food quality characteristics and immune responses (Cullen et al., Irish J. Agric. Food Res., 2005; Middleton & Kandaswami, Biochem. Pharmacol. 1992). Plant such as Oregano (Origanum vulgare) has attracted great interest as its esse...
Article
In the present work we conducted a comprehensive chemical analysis of blue honeysuckle (Lonicera caerulea) spontaneously growing in eastern Russia. HPLC-DAD-ESI/MS analysis showed cyanidin-3-glucoside as the major constituent among phenolics, while nutritional analysis revealed fibre, protein, calcium and magnesium as the most important macro- and...
Article
Full-text available
The milk antioxidants, by preventing lipid peroxidation, maintain milk quality, but they also exert a beneficial effect on the consumer's health, in particular that of infants. Donkey Milk (DM), for its nutritional, functional and bioactive components, seems to be one of the best substitutes of breast milk when the latter is not available. However,...
Article
Hypericum androsaemum, also known as Tutsan, is a small evergreen shrub common in the Mediterranean basin where it is traditionally used as diuretic and hepatoprotective herbal drug. This plant possesses the peculiarity to produce fleshy and berry-like fruits that ripen from red to shiny black. In the present work, the chemical constituents of meth...
Article
Full-text available
A 57-day study was performed to determine the effects of two aqueous extracts (AEs) on broiler performance, immune function and intestinal microflora. Four groups of 75 one-day-old female broilers (Ross308) received one of the following treatments: (1) a standard commercial feed (C); (2) C supplemented with 2 g/kg rosemary AE (R); (3) C supplemente...
Article
Full-text available
Trachyspermum ammi (Apiaceae) is a plant with a good reputation in the traditional Persian and Ajurvedic medicine. The hydrodistilled essential oil from the fruits of T. ammi, known as ‘ajwain oil’, is used in countries like Iraq, Iran, Afghanistan, Pakistan, and India in the preparation of curry, to flavor several foods, as preservative, and in pe...
Article
As a result of issues arising from overheating and deterioration of feed in the silos of farmers during the summer months, company Gima SpA has installed on Pelleting Technology, a pilot plant of refrigeration. The goal of this research was to evaluate the effects of the refrigeration system of grain storage technology applied to the pelleting of f...
Article
Full-text available
In this study the effect of diets supplemented with extracts of oregano and/or rosemary (Origanum vulgare L. and/or Rosmarinus officinalis L.) on lipid metabolism, antioxidant status and sensory perceptions in meat was investigated in fattening pig. Eighty pigs were divided into five dietary groups (n.16/each identified as: control, C; 2: foil, F;...
Article
Full-text available
Cow’s milk protein allergy (CMPA) is an abnormal immunological response to cow milk proteins, which results in IgE-mediated reactions. The therapeutic strategy to respond to CMPA envisages the total elimination of milk or the administration of cow’s milk substitutes. For this reason the use of milk from other mammalian species was tested. Among the...
Article
Background The discovery of IL-17-producing CD4+ T helper (Th17) cells challenged the long-standing paradigm of Th1/Th2 cell immune response and shed some light on the pathogenic mechanisms of systemic autoimmune disorders. IL-17 in a pro-inflammatory cytokine which mediates target organs damage during the disease. To note, it has been recently obs...
Article
Growing evidence suggests that IL-17-producing T cells, lacking both CD4 and CD8 molecules and defined as double negative (DN) cells, play a pivotal role in the pathogenesis of a number of systemic autoimmune disorders. We recently demonstrated that this T-cell subset is expanded in the peripheral blood (PB) of patients with primary Sjögren's syndr...
Article
Full-text available
A small CD3+ T-cell population, that lacks both CD4 and CD8 molecules, defined as double negative (DN), is expanded in the peripheral blood of patients with systemic lupus erythematosus, produces IL-17 and accumulates in the kidney during lupus nephritis. Since IL-17 production is enhanced in salivary gland infiltrates of patients with primary Sjög...
Poster
Full-text available
Homeopathy remains one of the most controversial subjects in therapeutics. However, the potential use of homeopathic drugs to enhance the immune responses represent an attractive and alternative strategy for promoting human and animal welfare and health status. Scientific trials on animals, not conditioned by a ‘placebo effect’, could contribute to...
Article
Full-text available
The quality of meat obtained by Fabrianese heavy lambs (33kg) reared in the Italian Sibillini mountains national park under extensive conditions had been investigated. Twenty entire male lambs had been used in this experiment; the Longissimus Thoracis et Lumborum muscle, taken from all the 20 animals, was analyzed for chemical composition, fatty ac...
Article
The aim of this study was to validate an A/T single nucleotide polymorphism (SNP) corresponding to a LINE2 sequence located ∼1.1kb downstream of the IL-6 gene (SNP BIEC2-911738) and to determine if this variant is correlated with interleukin 6 (IL-6) modulation or with different plasma concentrations of Zn, Cu, Se and Fe. The frequency of the newly...
Article
Full-text available
The aim of this study was to determine the effects of age on chemical composition and tenderness of donkey meat. These characteristics were determined on Longissimus thoracis samples taken from 40 entire donkey males of Martina Franca breed slaughtered at 12 (Group 1, n = 20) and at 18 months (Group 2, n = 20) of age. Tenderness was evaluated at tw...
Article
Full-text available
Milk is one of the most common causes of food allergies among children under one year of age. No specific therapy exists for this allergy, and thus the only feasible response is to avoid assumption of milk and derived products. Studies conducted on the serum of children with hypersensi- tivity to milk have shown that caseins are the proteins with t...
Article
Full-text available
Hypoallergenic properties of ass’s milk protein fractions have been recently con- firmed, allowing ass’s milk to be considered as a valid substitute of the available hypoallergenic infant formulas. The objective of this study was to give a further contribution to the knowledge of ass’s milk safety and quality characteristics. A new procedure has be...
Article
The rheological and chemical characteristics of meat obtained from 12 Martina Franca donkey males, slaughtered at 14months of age and a mean final body weight of 169kg were determined. Meat samples were taken four days post mortem from muscles Longissimus thoracis et lumborum and Biceps femoris, colorimetric parameters were measured to determine L(...
Article
A study based on 15 entire donkey males was carried out to evaluate carcass quality and nutritional characteristics of meat obtained by these animals slaughtered at 15 months of age and a mean final body weight of 181kg. The meat had a low (2.02g/100g) fat content, an appreciable (22.8g/100g) protein content, and cholesterol content was 68.7mg/100g...
Article
Tenderness and mineral levels were determined in the Longissimus thoracis taken from 20 llama and 30 alpaca males reared in Peru and slaughtered at 25 months of age. Mineral contents were determined using an inductively coupled plasma emission spectrometer. Tenderness evaluation was determined two and seven days post slaughter using a Warner-Bratzl...
Article
This work shows a methodological approach carried out with the aim to evaluate the effort of different kind of pastoral system management. It is based upon an integrated research including vegetation sciences, nutriments chemical properties, alpine farming and animal physiology and anatomy.
Article
Full-text available
– A first serological survey to evaluate the presence of antibodies against Neospora caninum in alpaca (Lama pacos) was carried out. 104 sera, collected in June and in November 2004 from alpacas reared in Central Italy, were tested using a c-Elisa kit (VMRD, USA) in order to investigate the prevalence of infection and the possible involvement of N....
Article
This research examined the effects of dietary alpha-tocopheryl acetate (50 or 200 mg/kg diet) and selenium (Se, 0 or 0.5 ppm) supplementation on motion characteristics, oxidative stability and fertilizing ability of rabbit spermatozoa, fresh and stored for 24 h at 5 degrees C. The higher amount of dietary alpha-tocopheryl acetate increased the leve...
Article
This research examined the effects of dietary α-tocopheryl acetate (50 or 200mg/kg diet) and selenium (Se, 0 or 0.5ppm) supplementation on motion characteristics, oxidative stability and fertilizing ability of rabbit spermatozoa, fresh and stored for 24h at 5°C. The higher amount of dietary α-tocopheryl acetate increased the level of Vitamin E in t...
Article
The effect of parenteral administration of two subcutaneous injections of vitamin E and Se (5 mg and 0.1 mg/kg of body weight, respectively) during the dry period on the mammary health and milk somatic cell counts of 25 dairy ewes was investigated. Supplementation reduced somatic cell counts (5.4 vs. 6.0 log10) during the subsequent lactation but h...
Article
On 700 milk samples from single half udders of Comisana ewes, somatic cell count (SCC) and differential cell count (DCC) were determined, using a Fossomatic 90 cell counter (Foss Electric, Denmark) (SCCF) and milk smears stained with May Grünwald-Giemsa (DCCS). SCC and DCC were also determined with modified KOVAH SYSTEM (Hicor Biomedical Inc. Irvin...

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Projects (2)
Project
Evaluation of the effects on performance, oxidative and immunological status, product quality and consumer perception deriving from the inclusion of Origanum vulgare essential oil and sweet chestnut wood extracts in diets formulation for growing pigs reared indoor and outdoor