Daniel Martins

University of Essex · School of Computer Science and Electronic Engineering

While metasurface based intelligent reflecting surfaces (IRS) are an important emerging technology for future generations of wireless connectivity in its own right, the plans for the mass deployment of these surfaces motivate the question of their integration with other new and emerging technologies that would require mass proliferation. This quest...

Bacteria are microorganisms found in the human body, and almost in everywhere, that recently they have been investigated as human gut's health indicator. After colonizing a surface, bacterial populations form biofilms, which is their natural protection mechanism against physical attacks, harmful chemical compounds and environmental changes. Recent...

Synthetic logic circuits have been proposed as potential solutions for theranostics of biotechnological problems. One proposed model is the engineering of bacteria cells to create logic gates, and the communication between the bacteria populations will enable the circuit operation. In this paper, we analyse the quality of bacteria-based synthetic l...

Bacteria are known to interpret a range of external molecular signals that are crucial for sensing environmental conditions and adapting their behaviors accordingly. These external signals are processed through a multitude of signaling transduction networks that, include the Gene Regulatory Network (GRN). From close observation, the GRN resembles a...

Within many chemical and biological systems, both synthetic and natural, communication via chemical messengers is widely viewed as a key feature. Often known as molecular communication, such communication has been a concern in the fields of synthetic biologists, nanotechnologists, communications engineers, and philosophers of science. However, inte...

Bacterial cells are sensitive to a range of external signals used to learn the environment. These incoming external signals are then processed using a Gene Regulatory Network (GRN), exhibiting similarities to modern computing algorithms. An in-depth analysis of gene expression dynamics suggests an inherited Gene Regulatory Neural Network (GRNN) beh...

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and electrochemical sensing technologies. The computing can be flexibly integrated into the chip, but we focus on e...

Bacterial ecosystems are integrated with cascading molecular communications networks that contain redundant paths transmitting molecular signals through a shared medium, resulting in accumulation of diverse molecules. Due to a range of factors, including residual noise and channel attenuation, the information flow between bacterial populations can...

Alterations in the human Gut Bacteriome (GB) can be associated with human health issues, such as type-2 diabetes and obesity. Both external and internal factors can drive changes in the composition and in interactions of the human GB, impacting negatively on the host cells. This paper focuses on the human GB metabolism and proposes a two-layer netw...

The recent COVID-19 pandemic has driven researchers from different spectrum to develop novel solutions that can improve detection and understanding of SARS-CoV- 2 virus. In this article we propose the use of Intelligent Reflector Surface (IRS) and terahertz communication systems to detect violent expiratory aerosol cloud that are secreted from peop...

Synthetic biology has utilised engineering concepts for the rational design of biocompatible systems. Here we utilise two bacterial populations to create a modulated molecular channel coding scheme for molecular communications systems. We believe this approach can drive the development of more reliable biocompatible molecular communications systems...

In recent years, the Molecular Communications field has contributed with the development of new methods for biotechnological applications. Due to noise and memory effects typically found in molecular systems, the design of precise detection system becomes a challenging task. In this work, we present a robust deep learning voting system model to imp...

Some characteristics of the operation of synthetic biology system are not well-explained using digital electronics, but they can be modelled using analog electronics. In this paper, we contribute to the characterization of bacteria internal signal processing by using an analog circuit analysis to show the impact of the binding/unbinding of molecule...

In recent years, bacterial populations have been engineered to act as biological sensors able to improve human health by developing novel therapeutics and diagnostics. Nowadays, populations of engineered bacteria can be remotely controlled to perform some medical actions on-demand; however, it brings crucial concerns from the cybersecurity perspect...

The recent COVID-19 pandemic has driven researchers from different spectrum to develop novel solutions that can improve detection and understanding of SARS-CoV-2 virus. In this article we propose the use of Intelligent Reflector Surface (IRS) emitting terahertz signals to detect airborne respiratory aerosol cloud that are secreted from people. Our...

Alterations in the human gut bacteriome can be associated with human health issues, such as type-2 diabetes and cardiovascular disease. Both external and internal factors can drive changes in the composition and in the interactions of the human gut bacteriome, impacting negatively on the host cells. In this paper, we focus on the human gut bacterio...

While metasurface-based intelligent reflecting surfaces (IRS) are an important emerging technology for future generations of wireless connectivity in its own right, plans for the mass deployment of these surfaces motivate the question of their integration with other new and emerging technologies that would require such widespread deployment. This q...

The recent advancements in bio-engineering and wireless communications systems have motivated researchers to propose novel applications for telemedicine, therapeutics and human health monitoring. For instance, through wireless medical telemetry a healthcare worker can remotely measure biological signals and control certain processes in the organism...

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and electrochemical sensing technologies. The computing can be flexibly integrated into the chip, but we focus on e...

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and electrochemical sensing technologies. The computing can be flexibly integrated into the chip, but we focus on e...

Bacterial quorum sensing can be engineered with a view to the design of biotechnological applications based on their intrinsic role as a means of communication. We propose the creation of a positive feedback loop that will promote the emission of a superfolded green fluorescence protein from a bacterial population that will flow through hydrogel, w...

Studies have recently shown that the bacteria survivability within biofilms is responsible for the emergence of superbugs. The combat of bacterial infections, without enhancing its resistance to antibiotics, includes the use of nanoparticles to quench the quorum sensing of these biofilm-forming bacteria. Several sequential and parallel multi-stage...

The outbreak of Ebola virus in recent years has resulted in numerous research initiatives to seek new solutions to contain the virus. A number of approaches that have been investigated include new vaccines to boost the immune system. An alternative post-exposure treatment is presented in this paper. The proposed approach for clearing Ebola virus ca...

Nanomedicina visa revolucionar os métodos paradiagnóstico, tratamento e prevenção de doenças usando conceitosdas áreas de bio-tecnologia e nanotecnologia. Nanodispositivos serão capazes de realizar essas atividades a partir de informações na escala molecular. Tarefas complexas podem também ser efetuadas se esses nanodispositivos forem capazes de in...

In recent years, bacterial infections have become a major public health concern due to their ability to cooperate between single and multiple species resisting to various forms of treatments (e.g., antibiotics). One form of protection is through biofilms, where the bacteria produce a protective medium known as the Extracellular Polymeric Substances...

Este artigo apresenta uma caracterização matemática do ruído presente em uma planta de uma indústria nacional de grande porte. A investigação da característica espectral, bem como o equacionamento da função densidade de probabilidade do ruído gerado por ventiladores industriais permite elaborar técnicas mais eficientes de controle ativo do ruído af...

Este artigo apresenta uma caracterização matemática do ruído presente em uma planta de uma indústria nacional de grande porte. A investigação da função densidade de probabilidade do ruído gerado por ventiladores industriais se apresenta como uma alternativa interessante à metodologia tradicional para prever ruídos gerados por ventiladores. Sistemas...

This paper presents a new approach to measure and analyze the noise in an industrial plant. The measurements were made in a large footwear industry environment. The main goal of this study is develop a methodology to measure noise that adresses the Brazilian legislation and presents other important informations to help a future mitigation of the no...

The industrial environment provides many risks to workers, and the audible noise is one of them. Chronic exposure to audible noise may cause hearing damage physiological and worker’s body. On this dissertation is presented a methodology to analyse existing levels of sound pressure and the behaviour of audible noise in an industrial environment. A s...

Este artigo apresenta uma análise preliminar do ruído presente em uma planta de uma indústria nacional de grande porte. Os equipamentos utilizados em um ambiente industrial geram poluição sonora e podem afetar a saúde do trabalhador. A legislação atual contempla apenas a exposição a altos níveis de ruído, independentemente da sua característica esp...

Os sistemas de comunicação ótica no espaço livre, ou FSO, servem para estabelecer enlaces de comunicação do tipo wireless, ponto-a-ponto, a uma elevada taxa de dados e com alcances que podem variar de algumas centenas de metros a alguns quilômetros. Atualmente novos modelos de comunicação foram propostos e duas idéias se mostram bastante interessan...