Daniel Lawson

Daniel Lawson
Imperial College London | Imperial · Department of Life Sciences

About

132
Publications
49,784
Reads
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13,687
Citations
Citations since 2016
65 Research Items
6679 Citations
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201620172018201920202021202202004006008001,000
201620172018201920202021202202004006008001,000
Additional affiliations
January 2016 - present
Imperial College London
Position
  • Fellow
June 2005 - December 2015
European Molecular Biology Laboratory
Position
  • Coordinator
September 1995 - June 2005

Publications

Publications (132)
Article
Full-text available
The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB, https://veupathdb.org) represents the 2019 merger of VectorBase with the EuPathDB projects. As a Bioinformatics Resource Center funded by the National Institutes of Health, with additional support from the Welllcome Trust, VEuPathDB supports >500 organisms comprising inverteb...
Article
Full-text available
Following publication of the original article [1], it was reported that the article copyright was incorrect. The correct copyright statement is: © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021. The original article [1] has been corrected.
Article
Full-text available
Background The stable fly, Stomoxys calcitrans, is a major blood-feeding pest of livestock that has near worldwide distribution, causing an annual cost of over $2 billion for control and product loss in the USA alone. Control of these flies has been limited to increased sanitary management practices and insecticide application for suppressing larva...
Article
Full-text available
Background: The Asian tiger mosquito, Aedes albopictus, is a highly dangerous invasive vector of numerous medically important arboviruses including dengue, chikungunya and Zika. In four decades it has spread from tropical Southeast Asia to many parts of the world in both tropical and temperate climes. The rapid invasion process of this mosquito is...
Article
Full-text available
Background: New sequencing technologies have lowered financial barriers to whole genome sequencing, but resulting assemblies are often fragmented and far from 'finished'. Updating multi-scaffold drafts to chromosome-level status can be achieved through experimental mapping or re-sequencing efforts. Avoiding the costs associated with such approache...
Article
Full-text available
Background: Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate viviparity), a vertebrate blood-specific diet by both sexes, and obligate bacterial symbiosi...
Preprint
Full-text available
Background: The stable fly, Stomoxys calcitrans, is a major blood-feeding pest of livestock that has near worldwide distribution, causing an annual cost of over $2 billion for control and product loss in the United States alone. Control of these flies has been limited to increased sanitary management practices and insecticide application for suppre...
Article
Full-text available
Arthropods play a dominant role in natural and human-modified terrestrial ecosystem dynamics. Spatially-explicit arthropod population time-series data are crucial for statistical or mathematical models of these dynamics and assessment of their veterinary, medical, agricultural, and ecological impacts. Such data have been collected world-wide for ov...
Preprint
Full-text available
Background: Tsetse flies (Glossina sp.) are the sole vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate viviparity), a vertebrate blood specific diet by both sexes and obligate bacterial symbiosis....
Preprint
Full-text available
Background New sequencing technologies have lowered financial barriers to whole genome sequencing, but resulting assemblies are often fragmented and far from ‘finished’. Updating multi-scaffold drafts to chromosome-level status can be achieved through experimental mapping or re-sequencing efforts. Avoiding the costs associated with such approaches,...
Preprint
Full-text available
Arthropods play a dominant role in natural and human-modified terrestrial ecosystem dynamics. Spatially-explicit population time-series are crucial for statistical or mathematical models of these dynamics and assessment of their veterinary, medical, agricultural, and ecological impacts. Arthropod data have been collected world-wide for over a centu...
Article
Full-text available
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and pro...
Data
Pattern recognition receptors (PRRs) and cytokines
Data
Supplementary Figures, Supplementary Notes and Supplementary References
Data
fasta sequences of predicted secreted proteins (fasta)
Data
secretome B. glabrata, Interproscan annotation
Data
Pfam domain annotation of predicted secretome
Data
Predicted GPCR genes of Biomphalaria glabrata
Data
Conserved precursor miRNAs, Structural, location and thermodynamic
Data
Predicted bioactive cleavage products of neuropeptides
Data
Biomineralization transcripts from B. glabrata mantle tissue.
Data
Low-copy transposable elements (TE) abundance
Data
Conserved mature miRNAs B. glabrata and homologs
Data
conserved precursor miRNAs tissue distribution in B. glabrata
Data
Cardiac regulatory and structural genes in B. glabrata
Data
Identity of 34 B. pfeifferi and B. glabrata sequence homologs
Data
Sequence Identity of B. pfeifferi homologs to 162 B. glabrata genes from
Article
Full-text available
The authors note that Angela B. Lange should be added to the author list between Leonardo B. Koerich and José Manuel Latorre-Estivalis, and Ian Orchard should be added to the author list between Sheila Ons and Lucia Pagola. Angela B. Lange and Ian Orchard should be credited with supplying sequencing samples and conducting gene annotation and supple...
Article
Full-text available
Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic anaplasmosis, babesiosis and other diseases. The large genome reflects accumulation of repetitive DNA, new lineages of retro-tr...
Article
Full-text available
Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic anaplasmosis, babesiosis and other diseases. The large genome reflects accumulation of repetitive DNA, new lineages of retro-tr...
Data
Supplementary Figures 1-25, Supplementary Tables 1-38, Supplementary Note 1, Supplementary Methods and Supplementary References
Article
Full-text available
Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to...
Article
Full-text available
Significance Rhodnius prolixus is a major vector of Chagas disease, an illness caused by Trypanosoma cruzi which affects approximately 7 million people worldwide. This report describes the first genome sequence of a nondipteran insect vector of an important human parasitic disease. This insect has a gene repertoire substantially distinct from dipte...