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Herein, a novel fluorescent sensor has been developed for the detection of biothiols based on theoretical calculations of the stability constant of the complex between a Cu²⁺ ion and (E)-3-((2-(benzo[d]thiazol-2-yl)hydrazono)methyl)-7-(diethylamino) coumarin (BDC) as a fluorescent ligand. In this study, on the basis of density functional theory met...
A novel coumarin derivative (5) was synthesized and used as a colorimetric and fluorescent probe for selective detection of Cu²⁺ ions in the presence of other metal ions, with the detection limits of 5.7 and 4.0 ppb, respectively. Cu²⁺ ion reacts with probe 5 to form a 1:1 stoichiometry complex, resulting in a remarkable redshift of absorption maxi...
The paper presented initial calculated results obtained by molecular dynamics simulations of some CD38-micro and nanomolar inhibitor systems in vacuum using reactive force field ReaxFF. The ReaxFF software integrated in SCM's ADF has been used. The analysis and processing of results has been supplemented by VMD, CHIMERA and some external support so...
In this review, the calculations of the electronically excited states were introduced as the recent outstanding applications of quantum chemical calculations for developing the fluorescent sensors. The applications of the ground state and excited state optimized geometry‐based calculations for the absorption and fluorescence properties have been in...
This paper outlines the results of external assessment and the accreditation of educational quality of 17 non-state universities according to the Consolidated Document No. 06/2014 / VBHN-BGD & DT, implemented by 4 Educational Quality Centers and published the Resolution on social networks. The article also compares main reasons that the criteria ha...
University autonomy is regarded as the necessary condition to implement advanced university governance practices to improve and enhance the quality of higher education. It should be paid attention to how to grant autonomy to higher education institutions and how these institutions exercise autonomy to ensure the purpose of improving the efficiency...
A coumarin-based fluorescent sensor (7-Acryloxy-4-methylcoumarin, AMC) for biothiols has been studied by a combination of quantum chemical calculation and experimental investigation. The AMC selectively reacts with mercapto biomolecules via Michael addition, which can be served as a ratiometric fluorescent sensor for thiol-containing biomolecules....
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