
Danai Dimitra AngelidakiMax Planck Institute for Biology of Ageing | AGE · RNA-Binding Proteins in Metabolism and Ageing
Danai Dimitra Angelidaki
PhD in Biology
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2
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Introduction
Publications
Publications (2)
Amino acid (AA) availability is a robust determinant of cell growth through controlling mechanistic/mammalian target of rapamycin complex 1 (mTORC1) activity. According to the predominant model in the field, AA sufficiency drives the recruitment and activation of mTORC1 on the lysosomal surface by the heterodimeric Rag GTPases, from where it coordi...
Amino acid (AA) availability is a robust determinant of cell growth, through controlling mTORC1 activity. According to the predominant model in the field, AA sufficiency drives the recruitment and activation of mTORC1 on the lysosomal surface by the heterodimeric Rag GTPases, from where it coordinates the majority of cellular processes. Importantly...