Dana B Mcqueen

Northwestern University | NU · Argonne-Northwestern Solar Energy Research Center (ANSER)

To evaluate the impact of race on in-vitro fertilization (IVF) outcomes. Retrospective analysis. Private practice. All women who underwent a first autologous IVF cycle at Fertility Centers of Illinois from January 2010 to December 2012. Information was collected on baseline characteristics, cycle parameters, and outcomes. Race was self-reported. Cl...

Objective: To assess the effectiveness of luteal start vaginal micronized P in a recurrent pregnancy loss (RPL) cohort. Design: Observational cohort study using prospectively collected data. Setting: Not applicable. Patient(s): Women seen between 2004 and 2012 with a history of two or more unexplained pregnancy losses <10 weeks in size; endo...

To assess the prevalence of chronic endometritis in women with a history of recurrent early pregnancy loss (REPL) and/or fetal demise (FD). Observational cohort study using prospectively collected data. Recurrent pregnancy loss program in an academic medical center. Three hundred ninety-five women with a history of two or more pregnancy losses of l...

To evaluate the prevalence of chronic endometritis (CE) in women with recurrent pregnancy loss (RPL) and compare pregnancy outcomes in women with and without CE. Case control observational study. Academic fertility practice. Women with two or more pregnancy losses. Hematoxylin and eosin (H & E) staining was performed on all endometrial biopsies and...

Study question: Does an association exist between high normal numbers of CGG trinucleotide repeats on the fragile X mental retardation 1 (FMR1) gene and diminished ovarian reserve (DOR)? Summary answer: This large data set demonstrated that a high normal number of CGG repeats (35-54 repeats) on the FMR1 gene was not significantly correlated with...

Objective To evaluate the association between embryo transfer techniques and pregnancy outcomes. Design This is a prospective observational study with a retrospective cohort. Setting University Clinic. Patients Patients underwent embryo transfers between 2015 and 2020. Intervention/Exposure Fourteen physicians performed 25 mock embryo transfers...

The objective of this study was to evaluate prevalence of chronic endometritis in a cohort of patients with retained pregnancy tissue (RPT) following miscarriage, with and without a history of recurrent pregnancy loss (RPL). In a cohort of our single academic fertility centre, we evaluated women with unexplained RPL (two or more losses) without evi...

Objective To determine if there is a relationship between paternal factors and embryonic aneuploidy of paternal origin using preimplantation genetic testing for aneuploidy (PGT-A). Design Retrospective cohort. Setting Academic. Participants Couples undergoing in vitro fertilization with PGT-A. Interventions None. Main outcome measure To determ...

Objective To evaluate the relationship between maternal body mass index (BMI) and embryonic aneuploidy of maternal origin. Design Retrospective cohort analysis. Setting University hospital-based reproductive center. Patients Maternal origin of aneuploidy was available for 453 cycles and 1,717 embryos. Interventions Data regarding BMI were colle...

Objective To assess the relationship between maternal body mass index (BMI) and embryo morphokinetics on time-lapse microscopy (TLM).DesignRetrospective cohort study.Methods All IVF cycles between June 2015 and April 2017 were reviewed. Female BMI prior to egg retrieval was collected through chart review. BMI (kg/m2) classification included underwe...

Objective To investigate the association of maternal body mass index (BMI) and recurrent pregnancy loss (RPL). Design Systematic review and meta-analysis. Setting Not applicable. Patient(s) A total of 3,833 women with RPL and 4,083 women as controls. Intervention(s) Studies were identified through a search of PubMed, Embase, Scopus, and Cochran...

Objective To develop diagnostic criteria for chronic endometritis and compare the prevalence of chronic endometritis between women with recurrent pregnancy loss (RPL) and controls. Design Cohort study. Setting Single academic fertility center. Patients Women with unexplained RPL (two or more pregnancy losses) and prospectively recruited controls...

PurposeTo evaluate perceptions of delayed fertility care secondary to the COVID-19 pandemic.Methods This was a cross-sectional anonymous survey of N = 787/2,287 patients (response rate = 42.6%) from a single academic fertility center. Participants were randomized 1:1 to receive supplemental educational explaining the rationale behind recommendation...

Objective To study whether single nucleotide polymorphism array could be used to test tissue from ectopic pregnancy to distinguish whether ectopic pregnancies were aneuploid. Design Case series report Setting Academic medical center Patients 178 women who underwent surgery for ectopic pregnancy at Northwestern Memorial Hospital between 2015-2018...

Objective To use time-lapse imaging to compare embryo morphokinetic parameters between embryos resulting in euploid pregnancy loss and euploid embryos resulting in live birth. Design Retrospective cohort study. Setting Single academic fertility center. Patient(s) All euploid single embryo transfers between October 2015 and January 2018. Interve...

Objective To evaluate current national practices in embryo transfer (ET) training in United States reproductive endocrinology and infertility (REI) fellowship programs and live birth rates after ET performed by fellows versus attending physicians. Design Cross-sectional survey of U.S. fellowship program directors and fellows in 2019 and retrospect...

Objective To summarize current understanding of the effects of novel and prior coronaviruses on human reproduction, specifically male and female gametes, and in pregnancy. Design Review of English publications in PubMed and Embase to April 6, 2020. Methods Manuscripts were screened for reports including coronavirus, reproduction, including pathop...

Research question Is minority race associated with worse oocyte donation outcomes? Design Retrospective analysis of 926 oocyte recipients who underwent a donor cycle with fresh embryo transfer at a single fertility centre between January 2009 and June 2015. Race was self-reported. To adjust for repeat donors within the sample, mixed models were us...

Objective: To investigate the rate of sperm DNA fragmentation in male partners of women with recurrent pregnancy loss and fertile control women. Design: Systematic review and meta-analysis. Setting: Not applicable. Patient(s): A total of 579 male partners of women with recurrent pregnancy loss and 434 male partners fertile control women. In...

Objective: To characterize the available support for infertility treatment and populations served by private foundations across the United States. Design: Web-based cross-sectional survey. Setting: Not applicable. Patient(s): Not applicable. Intervention(s): None. Main outcome measure(s): Geographies and populations served, dollar-amount...

Rapid advances in genomics have expanded the use of chromosome testing following miscarriage. In addition to conventional cytogenetics, the availability of single nucleotide polymorphism microarray technology and array comparative geneomic hybridization have provided further options for clinicians. This review will cover the indications for testing...

Objective: To determine whether an association exists between maternal antithyroid antibodies and euploid miscarriage in women with recurrent early pregnancy loss (REPL). Design: Observational cohort study. Setting: Two academic medical centers. Patient(s): Women seen between 2004-2015 with a history of REPL, who were euthyroid or had subcli...

Therapeutic anticoagulation is required for all patients with prosthetic mitral valves. Anticoagulation with warfarin is recommended; however, warfarin is teratogenic in early pregnancy and therefore alternate anticoagulation regimens are suggested for pregnant patients. A 28-year-old gravida 2, para 1 woman at 36 weeks’ gestation with a prosthetic...

A system and method for measuring movements, utilizing one or more wireless accelerometers attached to one or more limbs of a human subject for the purpose of determining certain temporal and spatial gestures of the subject.

Mounting evidence shows that low-birth-weight and prematurity are related to serious health problems in adulthood, including increased body fat, decreased fitness, poor bone mineralization, pulmonary problems, and cardiovascular disease. There are data to suggest that increasing physical activity in preterm infants will have effects on short-term m...

In this paper we demonstrate a Markov model based technique for recognizing gestures from accelerometers that explicitly represents duration. We do this by embedding an Erlang-Cox state transition model, which has been shown to accurately represent the first three moments of a general distribution, within a Dynamic Bayesian Network (DBN). The trans...

There is emerging data that patterns of motor activity early in neonatal life can predict impairments in neuromotor development. However, current techniques to monitor infant movement mainly rely on observer scoring, a technique limited by skill, fatigue, and inter-rater reliability. Consequently, we tested the use of a lightweight, wireless, accel...

With a focus on the early stages of developing new assessment tools, we present an example of how researchers can apply qualitative data to the development of conceptual domains and specific items representing those domains for quantitative instruments. Specifically, our previous research examining mothers' perceptions and experiences of engaging i...

This paper reports on the requirements for, design of, and preliminary evaluation of a novel pervasive healthcare system for supporting the care of premature infants as they transition from hospital to home. In support of this system, we report the results of gesture sensing in a clinical setting and of interviews and focus groups with caregivers a...

To identify important factors that influence mothers' perceptions of engaging in exercise with their preterm infants. Qualitative, semistructured individual interviews. Neonatal Intensive Care Unit. Thirteen mothers of preterm infants who were in the Neonatal Intensive Care Unit. Two researchers conducted interviews with mothers in English or Spani...

Members of the protein 4.1 family of adapter proteins are expressed in a broad panel of tissues including various epithelia where they likely play an important role in maintenance of cell architecture and polarity and in control of cell proliferation. We have recently characterized the structure and distribution of three members of the protein 4.1...