Dan Yamin

Dan Yamin
Tel Aviv University | TAU

PhD

About

65
Publications
4,318
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693
Citations

Publications

Publications (65)
Article
Halting the rapid clinical deterioration, marked by arterial hypoxemia, is among the greatest challenges clinicians face when treating COVID-19 patients in hospitals. While it is clear that oxygen measures and treatment procedures describe a patient’s clinical condition at a given time point, the potential predictive strength of the duration and ex...
Preprint
COVID-19 remains a global concern due to vaccine protection waning and the emergence of immune-evasive variants. While the effectiveness of a second booster vaccine dose (i.e., fourth inoculation) is well proven, its safety has yet to be fully understood, and vaccine compliance remains low. We conducted a prospective observational study to compare...
Article
Despite extensive technological advances in recent years, objective and continuous assessment of physiologic measures after vaccination is rarely performed. We conducted a prospective observational study to evaluate short-term self-reported and physiologic reactions to the booster BNT162b2 mRNA (Pfizer-BioNTech, https://www.pfizer.com) vaccine dose...
Article
Social networks' ability to disseminate content to millions of users with just one click has made them a major playground for political marketing. Campaigners seek to identify a small subset of seed users in a social network to maximize the spread of influence. However, political content diffusion has a distinct nature —some users may invert a mess...
Article
Full-text available
Background Clinical trial guidelines for assessing the safety of vaccines, are primarily based on self-reported questionnaires. Despite the tremendous technological advances in recent years, objective, continuous assessment of physiological measures post-vaccination is rarely performed. Methods We conducted a prospective observational study during...
Article
Full-text available
Social networks’ ability to disseminate content to millions of users with just one click has made them a major playground for political marketing. Campaigners seek to identify a small subset of seed users in a social network to maximize the spread of influence. However, political content diffusion has a distinct nature—some users may invert a messa...
Preprint
Background: The rapid rise in hospitalizations associated with the Delta-driven COVID-19 resurgence, and the imminent risk of hospital overcrowding, led the Israeli government to initialize a national third (booster) COVID-19 vaccination campaign in early August 2021, offering the BNT162b2 mRNA vaccine to individuals who received their second dose...
Article
Full-text available
Background Influenza is a substantial cause of morbidity and mortality for Israel and the Palestinian territory. Given the extensive interaction between the two populations, vaccination in one population may indirectly benefit the other via reduced transmission. Due to the mobility and extensive contacts, Palestinians employed in Israel could be a...
Article
Current COVID-19 screening efforts mainly rely on reported symptoms and the potential exposure to infected individuals. Here, we developed a machine-learning model for COVID-19 detection that uses four layers of information: (i) sociodemographic characteristics of the individual, (ii) spatio-temporal patterns of the disease, (iii) medical condition...
Article
Background: Contact mixing plays a key role in the spread of COVID-19. Thus, mobility restrictions of varying degrees up to and including nationwide lockdowns have been implemented in over 200 countries. To appropriately target the timing, location, and severity of measures intended to encourage social distancing at a country level, it is essentia...
Article
Full-text available
Vaccination is the most efficient means of preventing influenza infection and its complications. While previous studies have considered the externalities of vaccination that arise from indirect protection against influenza infection, they have often neglected another key factor–the spread of vaccination behavior among social contacts. We modeled in...
Article
Full-text available
Pertussis is a highly contagious bacterial disease that primarily affects infants. To optimize the pertussis vaccination schedule in Israel and evaluate the cost-effectiveness of alternative strategies that add or remove booster doses, we developed an age-structured model for pertussis transmission. Our model was calibrated using 16 years of data f...
Article
Full-text available
The unprecedented restrictions imposed due to the COVID-19 pandemic altered our daily habits and severely affected our well-being and physiology. The effect of these changes is yet to be fully understood. Here, we analysed highly detailed data on 169 participants for two to six months, before and during the second COVID-19 lockdown in Israel. We ex...
Preprint
Background Contact mixing plays a key role in the spread of COVID-19. Thus, mobility restrictions of varying degrees up to and including nationwide lockdowns have been implemented in over 200 countries. To appropriately target the timing, location, and severity of measures intended to encourage social distancing at a country level, it is essential...
Preprint
Background: Clinical trial guidelines for assessing the safety of vaccines, including the FDA criteria, are primarily based on subjective, self-reported questionnaires. Despite the tremendous technological advances in recent years, objective, continuous assessment of physiological measures post-vaccination is rarely performed. Methods: To evaluate...
Article
Full-text available
Since the emergence of the SARS-CoV-2 pandemic, various genetic variants have been described. The B.1.1.7 variant, which emerged in England during December 2020, is associated with increased infectivity. Therefore its pattern of spread is of great importance. The Israeli government established three national programs: massive RT-PCR testing, focuse...
Article
Full-text available
Social media networks have become an essential tool for sharing information in political discourse. Recent studies examining opinion diffusion have highlighted that some users may invert a message's content before disseminating it, propagating a contrasting view relative to that of the original author. Using politically-oriented discourse related t...
Article
Full-text available
The internet is flooded with malicious content that can come in various forms and lead to information theft and monetary losses. From the ISP to the browser itself, many security systems act to defend the user from such content. However, most systems have at least one of three major limitations: 1) they are not personalized and do not account for t...
Article
Full-text available
Background Applying heavy nationwide restrictions is a powerful method to curtail COVID-19 transmission but poses a significant humanitarian and economic crisis. Thus, it is essential to improve our understanding of COVID-19 transmission, and develop more focused and effective strategies. As human mobility drives transmission, data from cellphone d...
Article
Full-text available
Background Seasonal influenza remains a major cause of morbidity and mortality in the USA. Despite the US Centers for Disease Control and Prevention recommendation promoting the early antiviral treatment of high-risk patients, treatment coverage remains low. Methods To evaluate the population-level impact of increasing antiviral treatment timeline...
Preprint
Current efforts for COVID-19 screening mainly rely on reported symptoms and potential exposure to infected individuals. Here, we developed a machine-learning model for COVID-19 detection that utilizes four layers of information: 1) sociodemographic characteristics of the tested individual, 2) spatiotemporal patterns of the disease observed near the...
Preprint
Full-text available
Since the emergence of the SARS-CoV-2 pandemic various generic variants have been described. Of specific interest is a new variant, which was observed in England during December 2020 and is now termed B.1.1.7. This variant is now associated with increased infectivity and therefore its spread within the community is of great importance. The Israeli...
Article
Full-text available
Low adherence to prescribed medications causes substantial health and economic burden. We analyzed primary data from electronic medical records of 250,000 random patients from Israel’s Maccabi Healthcare services from 2007 to 2017 to predict whether a patient will purchase a prescribed antibiotic. We developed a decision model to evaluate whether a...
Preprint
Seasonal influenza remains a major health burden in the United States. Despite recommendations of early antiviral treatment of high-risk patients, the effective treatment coverage remains very low. We developed an influenza transmission model that incorporates data on infectious viral load, social contact, and healthcare-seeking behavior, to evalua...
Preprint
Background Applying heavy nationwide restrictions is a powerful method to curtail COVID-19 transmission but poses a significant humanitarian and economic crisis. Thus, it is essential to improve our understanding of COVID-19 transmission and develop more focused and effective strategies. As human mobility drives transmission, data from cell phone d...
Preprint
Full-text available
The unprecedented COVID-19 pandemic that swiped across the globe led many countries to apply heavy nationwide restrictions and control measures. Analyzing aggregate and anonymized 15 mobility data from the cell-phone devices of>3 million users in Israel, we identified that poorer 16 regions exhibited lower and slower compliance with the restriction...
Article
Full-text available
Background: Seasonal influenza vaccination coverage remains suboptimal in most developed countries, despite longstanding recommendations of public health organizations. The individual's decision regarding vaccination is located at the core of non-adherence. We analyzed large-scale data to identify personal and social behavioral patterns for influe...
Article
Pertussis incidence in developed countries, including Israel, has increased over the past two decades despite the addition of two booster doses in children. However, as pertussis is characterized by a multi-annual periodicity, and since clinical diagnosis can miss cases, determining disease trends at the population level is challenging. To bridge t...
Preprint
Full-text available
Background: Seasonal influenza vaccination coverage remains suboptimal in most developed countries, despite longstanding recommendations of public health organizations. The individual’s decision regarding vaccination is located at the core of non-adherence. We analyzed large-scale data to identify personal and social behavioral patterns for influen...
Preprint
Full-text available
Background Seasonal influenza vaccination coverage remains suboptimal in most developed countries, despite longstanding recommendations of public health organizations. The individual’s decision regarding vaccination is located at the core of non-adherence. We analyzed large-scale data to identify personal and social behavioral patterns for influenz...
Article
Full-text available
During the initial months of the 2013–2016 Ebola epidemic, rapid geographical dissemination and intense transmission challenged response efforts across West Africa. Contextual behaviours associated with increased risk of exposure included travel to high-transmission settings, caring for sick and preparing the deceased for traditional funerals. Alth...
Article
Full-text available
Respiratory syncytial virus (RSV) is the most common cause of US infant hospitalization. Additionally, RSV is responsible for 10,000 deaths annually among the elderly across the United States, and accounts for nearly as many hospitalizations as influenza. Currently, several RSV vaccine candidates are under development to target different age groups...
Article
Background: Vaccination against rotavirus has shown great potential for reducing the primary cause of severe childhood gastroenteritis. Previous economic evaluations of rotavirus vaccination in France have not modeled the potential impact of vaccines on disease burden via reduced transmission. Objective: To determine the cost-effectiveness of th...
Article
The 2014-2015 Ebola epidemic has been the most protracted and devastating in the history of the disease. To prevent future outbreaks on this scale, it is imperative to understand the reasons that led to eventual disease control. Here, we evaluated the shifts of Ebola dynamics at national and local scales during the epidemic in Liberia. We used a tr...
Article
Full-text available
Background Poverty has been implicated as a challenge in the control of the current Ebola outbreak in West Africa. Although disparities between affected countries have been appreciated, disparities within West African countries have not been investigated as drivers of Ebola transmission. To quantify the role that poverty plays in the transmission o...
Data
Heat maps depicting zone-level contact matrices for July, August, and September 2014. Montserrado County, Liberia is comprised of 22 zones. Case investigation data on the zones of residence for cases and their reported contacts were used to generate relative probabilities of contacts between and within zones. Increasingly less inter-zone contacts w...
Data
Frequency distributions for time between symptom onset and hospitalization from case investigation data. For each individual reporting current or prior hospitalization, the number of days between his/her date of symptom onset and date of hospital admission was calculated. Data are provided per epidemic month in 2014. (DOCX)
Data
Temporal trends in Ebola-related behaviors and case fatality, stratified by socioeconomic status (SES). Data are provided per epidemic month in 2014. (DOCX)
Data
Case classification data. The dataset consists information about individuals reported as suspected, probable, or confirmed Ebola cases in Montserrado County between February 28, 2014 and December 1, 2014. (XLSX)
Data
Frequency distributions for time between symptom onset and death from case investigation data. For each non-surviving case, the number of days between his/her date of symptom onset and date of death was calculated. Data are provided per epidemic month in 2014. (DOCX)
Data
Contact tracing data. The dataset consists of information on 1,585 suspected, probable, or confirmed cases whose contacts were traced between July 7, 2014 and October 28, 2014. (XLSX)
Data
Frequency distributions for the number of contacts per case from case investigation data. Data are provided per epidemic month in 2014. (DOCX)
Data
Histogram of a truncated gamma distribution for the rate ratio, or expected change in transmission rate given a tenfold change in viral load. (DOCX)
Article
Full-text available
Background: Contact patterns and vaccination decisions are fundamental to transmission dynamics of infectious diseases. We report on age-specific contact patterns in Japan and their effect on influenza vaccination behaviour. Methods: Japanese adults (N=3146) were surveyed in Spring 2011 to assess the number of their social contacts within a 24 h...
Article
Full-text available
There are two errors in Fig 1. In Fig 1, the label for the edge connecting the latent state (E) to the removed state (R) should be τχ. The label for the edge connecting the latent state (E) to the observed state (TE) should be τ(1-χ). Please see the corrected Fig 1 here. Fig 1 A) Our dynamic model is driven by the spatial correlation of individua...
Article
Full-text available
As a devastating Ebola outbreak in West Africa continues, non-pharmaceutical control measures including contact tracing, quarantine, and case isolation are being implemented. In addition, public health agencies are scaling up efforts to test and deploy candidate vaccines. Given the experimental nature and limited initial supplies of vaccines, a mas...
Article
Using Ebolavirus genomic and epidemiological data, we conduct the first joint analysis where both data types are used to fit dynamic transmission models for an ongoing outbreak. Our results indicate that transmission is clustered, highlighting a potential bias in medical demand forecasts, and provide the first empirical estimate of underreporting....
Article
Full-text available
Background: The Ebola outbreak that is sweeping across West Africa is the largest, most volatile, and deadliest Ebola epidemic ever recorded. Liberia is the most profoundly affected country, with more than 3500 infections and 2000 deaths recorded in the past 3 months. Objective: To evaluate the contribution of disease progression and case fatali...
Article
Full-text available
Influenza vaccination is the primary approach to prevent influenza annually. WHO/CDC recommendations prioritize vaccinations mainly on the basis of age and co-morbidities, but have never considered influenza infection history of individuals for vaccination targeting. We evaluated such influenza vaccination policies through small-world contact netwo...
Article
Full-text available
Background Influenza vaccination is the most efficient and cost-effective method to prevent influenza. To increase vaccination coverage, health authorities use various intervention programs (IPs), such as cost subsidies or placing vaccination centers in malls to make vaccination more accessible. Nevertheless, vaccination coverage has been sub-optim...
Article
In the majority of developed countries, the level of influenza vaccination coverage in all age groups is suboptimal.Hence, the authorities offer different kinds of incentives for people to become vaccinated such as subsidizing immunization or placing immunization centers in malls to make the process more accessible. We built a theoretical epidemiol...
Article
The history of HIV/AIDS in Romania is different compared to the rest of the world. Here, the vast majority of HIV-positive patients have been infected since infancy and have been receiving HAART treatment for at least ten years. This situation is a unique environment to check for long-term cardiac involvement in HIV-positive patients with a long ev...
Article
Full-text available
Background: Influenza vaccination is the most efficient and cost-effective method to prevent influenza. WHO/CDC recommendations have never considered the effect of previous individual illness on determining future vaccination policy for that individual.Methods: Several Contact networks epidemiology simulations, and, independently, empirical validat...
Conference Paper
Purpose: Vaccination is the most efficient and cost effective method to prevent influenza, reducing morbidity and mortality rates not only for those vaccinated, but also for the entire population by reducing the spread of the virus. In the context of contact network epidemiology, an individual who is located in the center of the network is more lik...

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