Damla Serçe Unat

• Md at Dr. Suat Seren Göğüs Hastalıkları Ve Cerrahisi Eğitim Ve Araştırma Hastanesi

Introduction: Brain Metastasis (BM) in Non-Small Cell Lung Cancer (NSCLC) is still important reason of morbidity and mortality despite the advances in the cancer treatment. Using Tyrosine Kinase Inhibitors against Epidermal Growth Factor Receptors (EGFR) mutations revolutionized in NSCLC treatment. We investigated whether the presence of EGFR mutat...

Background and aim There is not any available test that provides sufficient prognostic information to guide treatment decisions in idiopathic pulmonary fibrosis (IPF). The aim of our study was to determine the predictive factors of mortality in patients with IPF treated with antifibrotics. Methods Patients with diagnosis of IPF who were treated wi...

OBJECTIVE: The optimal anticoagulant treatment regimen in hospitalized coronavirus disease 2019 (COVID-19) patients is uncertain. This study aimed to compare the rates of disease progression and mortality in patients treated with low-molecular-weight heparin (LMWH) according to baseline d-dimer levels and in those who received a fixed-dose regimen...

Introduction: Unlike other laboratory tests, spirometry requires the participant’s full compliance with the maneuvers in the test for an acceptable test result. In this study, we aimed to determine the suitability of spirometric tests regarding acceptability and the factors associated with acceptability. Materials and methods: Before the test, o...

Giriş: Alt solunum yolu enfeksiyonları (ASYE) hastaneye ayaktan başvurularda ve yatan hastalarda önemli mortalite ve morbidite nedenidir. Hastane yatışı gerektiren ASYE vakalarında antibiyoterapinin zamanında başlanması önemlidir. Enfeksiyon tablosuna yol açan etkeni belirlemek için solunum yolu kültürleri alınmadan başlanan ampirik antibiyoterapi...

Infections are still among the most important causes of morbidity and mortality in patients with lung cancer, which has the highest rate of cancer-related deaths in the world. Microsporidia, which are opportunistic parasitic fungi, primarily localize to the intestine by ingestion but can disseminate to the respiratory tract or can be acquired by sp...

Introduction: The purpose of this study is to determine how long patients who developed pneumothorax were followed up on in the emergency department, how many patients required chest tube placement, and what factors influenced the need for a chest tube in patients who underwent computed tomography (CT)-guided percutaneous transthoracic fine needle...

Objective: In this study, we aimed to evaluate the role of 18F-fluorodeoxyglucose PET/computerized tomography (18F-FDG PET/CT)-based radiomic features in the differentiation of infection and malignancy in consolidating pulmonary lesions and to develop a prediction model based on radiomic features. Material and methods: The images of 106 patients...

Introduction: Infection complications in lung cancer (LC), one of the most common cancers in the world, are still among the most important causes of death. Of them, P. jirovecii, which is as an opportunistic infection, causes a life-threatening type of pneumonia in cancer patients. This preliminary study aimed to determine the incidence and clinic...

Objective: Various studies have shown that diabetes mellitus (DM) increases the risk of thrombosis in the venous system as well as in the arterial system. In this study, it was aimed to evaluate the association between admission blood glucose levels and clinical severity, recurrence, and mortality in pulmonary embolism in patients with DM. Materi...

Introduction: The optimal anticoagulant treatment regimen in hospitalized COVID-19 patients is debated amid studies investigating the effectiveness of different dosing strategies. Aims and Objectives: The aim of this study was to compare the rates of disease progression and mortality in patients treated with LMWH according to a protocol based on b...

Although diagnostic and therapeutic advances in Lung cancer (LC) have increased the survival of patients, infection and its complications are still among the most important causes of mortality. The disruption of tissue caused by tumor mass, management of cancer therapy and alteration in the humoral/cellular immune systems due to both cancer itself...

Objective: The aim of this study is to determine the role of metabolic and volumetric parameters obtained from 18Fluorine-Fluorodeoxyglucose PET/computed tomography (18F-FDG PET/CT) imaging on progression-free survival (PFS) and overall survival (OS) in patients with advanced nonsquamous cell lung carcinoma (NSCLC) with anaplastic lymphoma kinase...

Lung carcinoma is one the most common cancer and the leading cause of cancer-related death worldwide. Increasing evidences have shown that Cryptosporidium spp., an opportunistic parasite, is associated with cancers, causing a life-threatening infection. The most common clinical form of Cryptosporidium is intestinal infection. However, respiratory c...

Background: Coronavirus disease 2019 (COVID-19) related chronic lung changes secondary to severe disease have become well known. The aim of this study was to determine the risk factors that affect the development of interstitial lung disease in subjects with COVID-19 pneumonia who were hospitalized. Methods: Patients hospitalized with COVID-19 p...

Introduction: Antibiotics reduce the risk of short-term mortality. Certain bacteria may be resistant to initial regimens which is related to mortality. The aim of this study was to find risk factors for the presence of resistant bacteria during exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Materials and Methods: Ethics committee ap...

Background: Direct oral anticoagulants (DOACs) have been used in acute pulmonary thromboembolism as an alternative to warfarin due to drug interactions, narrow therapeutic range, and necessary close International Normalized Ratio (INR) monitoring. Phase 3 study results have reported that these drugs are at least as effective as warfarin and benefi...

COVID-19 hastalığının patogenezinde tromboembolik süreçlerin çok etkin olduğu bilinmektedir. Tromboembolizm ve D-dimer artışının kötü prognoz ve mortalite ile ilişkili olduğu saptanmıştır. Bu nedenle COVID-19 hastalığı tedavisinde düşük molekül ağırlıklı heparin (DMAH) kullanımı oldukça yaygındır. COVID-19 pnömonisi olup pulmoner tromboemboli (PTE)...

INTRODUCTION: Pulmonary thromboembolism (PTE) is a disease that mortal and hardly diagnosed. Since findings of PTE are nonspesific diagnosed can be so hard sometimes. Major risk factors are malignancy, immobility, previous surgery, thrombophilia, advanced age, and genetic factors. Studies on the relationship between gender and prognosis in PTE have...