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In global cancer statistics, colorectal carcinoma (CRC) ranks third by incidence and second by mortality, causing 10.0% of new cancer cases and 9.4% of oncological deaths worldwide. Despite the development of screening programs and preventive measures, there are still high numbers of advanced cases. Multiple problems compromise the treatment of met...
Heterogeneity is a characteristic feature of malignant tumours. It challenges the treatment regimens as well as can impair the diagnostic accuracy. Glioblastoma multiforme (GBM), a high-grade malignant glial tumour, is known for the extreme morphological heterogeneity giving rise also to the term itself. was to evaluate heterogeneity of pathogeneti...
Glioblastoma (GBM) has very poor prognosis despite aggressive therapy including surgical treatment. At present, few molecular markers could clarify GBM prognosis in greater detail. However, better understanding of the molecular pathogenesis would be the mainstay of improved, more personalized treatment modalities. Recent large-scale molecular studi...
In dogs with pH-electrodes indwelled in different portions of the stomach and duodenum, the zone of maximal hydrochloric acid formation was found in the angle area of the minor curvature. The bottom area of the stomach also revealed a high acid-forming function. The intrastomach milieu on the major curvature from the body till antral portion reveal...