Dafna Sussman

Dafna Sussman
Ryerson University · Faculty of Engineering and Architectural Science

PhD in Medical Biophysics and Clinical Imaging

About

36
Publications
7,612
Reads
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430
Citations
Additional affiliations
July 2013 - present
SickKids
Position
  • Research Associate

Publications

Publications (36)
Article
Full-text available
Fetal MR imaging is subject to artifacts including motion, chemical shift, and radiofrequency artifacts. Currently, such artifacts are detected by the MRI operator, a process which is subjective, time consuming, and prone to errors. We propose a novel algorithm, RISE-Net, that can consistently, automatically, and objectively detect artifacts in 3D...
Article
Amniocentesis is the process of retrieving the nutrient‐rich amniotic fluid (AF) that encompasses the growing fetus in order to diagnose fetal diseases and developmental disorders. Currently, it is only performed on pregnant persons at risk and is invasive with the potential for infection and in some cases, miscarriage. A non‐invasive alternative i...
Article
Full-text available
Rapid development in Magnetic Resonance Imaging (MRI) has played a key role in prenatal diagnosis over the last few years. Deep learning (DL) architectures can facilitate the process of anomaly detection and affected-organ classification, making diagnosis more accurate and observer-independent. We propose a novel DL image classification architectur...
Article
Full-text available
Deep learning (DL) algorithms have become an increasingly popular choice for image classification and segmentation tasks; however, their range of applications can be limited. Their limitation stems from them requiring ample data to achieve high performance and adequate generalizability. In the case of clinical imaging data, images are not always av...
Article
OBJECTIVE To synthesize peer-reviewed evidence related to the use of artificial intelligence (AI) in surgical education DESIGN We conducted and reported a scoping review according to the standards outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis with extension for Scoping Reviews guideline and the fourth edition o...
Article
Objective To provide a systematic review of available brain MRI phantoms for comparison of structural and functional characteristics.Materials and methodsPhantoms were identified from a literature search using two databases including Google Scholar and PubMed. Narrow inclusion criteria were followed for identification of only tissue-mimicking MRI p...
Article
Full-text available
Segmentation of the fetus from 2-dimensional (2D) magnetic resonance imaging (MRI) can aid radiologists with clinical decision making for disease diagnosis. Machine learning can facilitate this process of automatic segmentation, making diagnosis more accurate and user independent. We propose a deep learning (DL) framework for 2D fetal MRI segmentat...
Article
Full-text available
Silicone rubber’s silicone-oxygen backbones give unique material properties which are applicable in various biomedical devices. Due to the diversity of potential silicone rubber compositions, the material properties can vary widely. This paper characterizes the dielectric and mechanical properties of two different silicone rubbers, each with a diff...
Article
Objective To provide a review and quantitative analysis of the available fetal MR imaging phantoms. Materials and methods A literature search was conducted across Pubmed, Google Scholar, and Ryerson University Library databases to identify fetal MR imaging phantoms. Phantoms were graded on a semi-quantitative scale in regards to four evaluation ca...
Article
Objective: This study aims to non-invasively quantify blood flow in the uterine arteries (UTA) and umbilical vein (UV) using phase-contrast magnetic resonance imaging (PC-MRI), and test whether these correlate with maternal fitness parameters. Method: Resting UTA and UV flows were measured in 23 healthy 30±3 year-old women who engaged in moderat...
Article
Objectives Fetal spina bifida is associated with progressive hydrocephalus, leading to postnatal ventriculoperitoneal shunting. The aim of this study was to document the evolution of the size of the fetal lateral ventricles throughout pregnancy in fetuses with spina bifida and to assess whether fetal surgery had a measurable impact on ventricular s...
Data
video of fetal blood flow acquired using multidimensional flow encoding (3D flow-encoding within a 2D slice, in-plane flows shown for clarity).
Article
Purpose: To image multidimensional flow in fetuses using golden-angle radial phase contrast cardiovascular magnetic resonance (PC-CMR) with motion correction and retrospective gating. Methods: A novel PC-CMR method was developed using an ungated golden-angle radial acquisition with continuously incremented velocity encoding. Healthy subjects (n = 5...
Article
Concussion induces transient, and oftentimes chronic, lingering impairment to mental functioning, which must be driven by some underlying neurobiological perturbation – however, the physical changes related to sequelae are difficult to detect. Previous imaging studies on concussion have focused on alterations to cortical anatomy, but few have exami...
Article
Full-text available
Background: Posttraumatic stress disorder (PTSD), an anxiety disorder that can develop after exposure to psychological trauma, impacts up to 20% of soldiers returning from combat-related deployment. Advanced neuroimaging holds diagnostic and prognostic potential for furthering our understanding of its etiology. Previous imaging studies on combat-re...
Article
Full-text available
Introduction: This study is the first to characterize normal development and sex differences across neuroanatomical structures in cortical, subcortical, and cerebellar brain regions in a single large cohort. Methods: One hundred and ninety-two magnetic resonance images were examined from 96 typically developing females and 96 age-matched typical...
Article
Regular physical activity during an uncomplicated pregnancy has been shown to improve health-related pregnancy outcomes while being harmless for the fetus. The benefits of regular exercise led the American Association of Obstetricians and Gynaecologists (ACOG) to recommend that a minimum of 30 min of moderate exercise a day occurs on most days of t...
Article
Full-text available
Autism Spectrum Disorder (ASD) is a clinically diagnosed, heterogeneous, neurodevelopmental condition, whose underlying causes have yet to be fully determined. A variety of studies have investigated either cortical, subcortical, or cerebellar anatomy in ASD, but none have conducted a complete examination of all neuroanatomical parameters on a singl...
Article
Full-text available
IntroductionThe ketogenic diet (KD) has seen an increase in popularity for clinical and non-clinical purposes, leading to rise in concern about the diet's impact on following generations. The KD is known to have a neurological effect, suggesting that exposure to it during prenatal brain development may alter neuro-anatomy. Studies have also indicat...
Article
Full-text available
The use of the ketogenic diet (KD) among women of child-bearing age has been increasing, leading to increased interest in identifying the diet's suitability during gestation. To date, no studies have thoroughly investigated the effect of a gestational KD on offspring growth. Since ketones have been reported to play a role in cerebral lipid and myel...
Article
Full-text available
Fragile X Syndrome is the most common inherited cause of autism. Fragile X mental retardation protein (FMRP), which is absent in fragile X, is an mRNA binding protein that regulates the translation of hundreds of different mRNA transcripts. In the adult brain FMRP is expressed primarily in neurons; however, it is also expressed in developing glial...
Article
Full-text available
Background The increasing use of the ketogenic diet (KD), particularly by women of child-bearing age, raises a question about its suitability during gestation. To date, no studies have thoroughly investigated the direct implications of a gestational ketogenic diet on embryonic development. Methods To fill this knowledge gap we imaged CD-1 mouse em...
Article
Full-text available
This paper presents an anatomically-correct eye model for the ground squirrel, a diurnal, highly-developed mammal with high visual acuity. This model can assist in understanding the relationship between ocular structural development and its corresponding function. The eye model is constructed based on anatomical measurements of thicknesses and indi...
Article
We present the results of the design studies of the science calibration system for the adaptive optics and infrared instruments of the Thirty Meter Telescope. The two major requirements of the science calibration system are to provide pupil-simulated telescope beams to the adaptive optics system for calibration of the telescope pupil and to provide...
Conference Paper
The rat eye model of age-related macular degeneration can give both high resolution imaging of fundus structures and localized light delivery in potential therapies. We induced and tracked AMD-like damage in vivo.
Conference Paper
Anatomical elliptical and spherical GRIN models of the rat eye are constructed in Zemax. The elliptical model agrees better with experimental measurements of spherical aberration and HO-RMS 20deg. off-axis than the spherical model.

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