Czernych Radoslaw

• PhD
• Assistant at Medical University of Gdansk

(1) Background: Haemorrhagic strokes (HS), including intracerebral (ICH) and subarachnoid haemorrhages (SAH), account for approximately 10–15% of strokes worldwide but are associated with worse functional outcomes and higher rates of mortality, and financial burden than ischemic stroke. There is evidence that confirmed poor air quality may increase...

The presented study investigates and compares the genotoxic potential of four commonly used diesters of phthalic acid (phthalates) in the presence and absence of S9 metabolic activation by using the SOS/umuC assay on Salmonella typhimurium TA1535 [pSK1002]. Phthalates are plasticizers with a wide range of applications for manufacturing plastic and...

(1) Background: More than 1.8 million people in the European Union die every year as a result of CVD, accounting for 36% of all deaths with a large proportion being premature (before the age of 65). There are more than 300 different risk factors of CVD, known and air pollution is one of them. The aim of this study was to investigate whether daily c...

Indoor air quality is strongly affected by the contamination of ambient air and that related to building and finishing materials and to human activity. Poor ventilation of closed spaces facilitates retention of greater quantity of pollutants. Infants and children are at particular risk of exposure to indoor air pollutants as they undergo rapid phys...

The presented study investigates and compares the estrogenic and androgenic activities of commonly used diesters of phthalic acid (phthalates) using the XenoScreen YES/YAS assay. Phthalates are commonly used plasticizers in polymers dedicated for i.e. food and drug containers. Since phthalates are not chemically bonded to the polymer, they can leac...

Shale gas exploitation by hydraulic fracturing involves a number of environmental hazards, among which the neutralization and management of fracturing flowback waters is of particular importance. Chemical compounds present in the flowback water mainly constitute a threat to surface waters. The aim of our research was to determine the effects of the...

Plasticisers such as bisphenol A (BPA), bisphenol S (BPS), and phthalates (PAE) are commonly used in daily life in electronic equipment, cans, plastic food containers, and bottles. These substances can interact with oestrogen receptors as well as androgen receptors and therefore they are called endocrine disrupting chemicals (EDC). The aim of this...

Although there are numerous publications on the monitoring of emerging contaminants (ECs), the vast majority of them do not address the monitoring of metabolites and transformation products (TPs) of the parent compounds. ECs, depending on their stability in an environment and metabolic pathways, may exist in either substantially smaller or larger a...

A rapid and selective method for trace amounts determination of cyclophosphamide in surface water samples has been developed. A solid phase extraction SPE method for extraction and clean-up procedure has been optimized for determination by reversed-phase high-performance liquid chromatography with tandem mass spectrometry. The analyses proceed in t...

Indoor air quality is strongly affected by the contamination of ambient air as well as contaminants related with indoor materials and certain daily human activities. The group of distinctive concern, when the exposure to indoor air pollutants is concerned, are infants and children. The pace of physiological and biochemical changes that children und...

Indoor pollutants can enter our bodies by ingestion, inhalation or skin infiltration. The principal effects of exposure are related to the size of the dose. Healthy indoor environments should contain only low levels of chemicals and biological substances. The emissions of Volatile Organic Compounds (VOC's) from building and furniture materials can...