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Cynthia E Krafft

Cynthia E Krafft

PhD

About

17
Publications
3,593
Reads
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1,113
Citations
Introduction
Skills and Expertise
Additional affiliations
July 2013 - December 2014
University of California, Davis
Position
  • PostDoc Position
August 2008 - May 2013
University of Georgia
Position
  • PhD Student

Publications

Publications (17)
Article
Aniridia is a panocular disorder characterized chiefly by iris hypoplasia. Most cases result from mutations of the PAX6 gene, which is important in both eye and brain development. In addition to ocular alterations, differences in global brain volume and functional connectivity have been reported in humans with aniridia. Understanding neural alterat...
Chapter
Childhood overweight/obesity and ADHD are common conditions of interest to researchers investigating the relationship between regular physical activity and children's cognition. Children in these populations are less physically active and have lower cognitive function than typically developing children. Research may identify the effects of regular...
Article
While antisaccade paradigms invoke circuitry associated with cognitive control and attention-deficit/hyperactivity disorder (ADHD), there is a dearth of functional magnetic resonance imaging (fMRI) investigations using antisaccade tasks among children with ADHD. Neural correlates associated with antisaccade performance were examined with fMRI in 11...
Article
Full-text available
Early adolescent onset of substance use is a robust predictor of future substance use disorders. We examined the relation between age of substance use initiation and resting state functional connectivity (RSFC) of the core reward processing (nucleus accumbens; NAcc) to cognitive control (prefrontal cortex; PFC) brain networks. Adolescents in a long...
Article
Hyperactivity is a key symptom and the most observable manifestation of attention-deficit/hyperactivity disorder (ADHD). The over-activity associated with ADHD can cause specific challenges in academic settings, extracurricular activities and social relationships. Cognitive control challenges are also well established in ADHD. The current study inc...
Article
Full-text available
Attention Deficit/Hyperactivity Disorder (ADHD) is associated with different impairment profiles in the symptom domains of hyperactivity/impulsivity and/or inattention. An additional symptom domain of sluggish cognitive tempo (SCT) has also been proposed. Although there is a degree of correlation between the SCT symptom domain and inattention, it h...
Article
Full-text available
Mutations affecting the PAX6 gene result in aniridia, a condition characterized by the lack of an iris and other panocular defects. Among humans with aniridia, structural abnormalities also have been reported within the brain. The current study examined the functional implications of these deficits through "resting state" or task-free functional ma...
Article
Cognitive control is required for flexible responses in changing environments and can be assessed by measuring antisaccade error rate. Considerable variance in antisaccade error rate is observed in healthy participants, which motivated the current study to explore the cognitive factors affecting antisaccade performance. Relationships exist between...
Article
During childhood, verbal learning and memory are important for academic performance. Recent functional MRI studies have reported on the functional correlates of verbal memory proficiency, but few have reported the underlying structural correlates. The present study sought to test the relationship between fronto-temporal white matter integrity and v...
Article
In childhood, excess adiposity and low fitness are linked to poor academic performance, lower cognitive function, and differences in brain structure. Identifying ways to mitigate obesity-related alterations is of current clinical importance. This study examined the effects of an 8-month exercise intervention on the uncinate fasciculus, a white matt...
Article
Full-text available
Aerobic fitness is associated with white matter integrity (WMI) in adults as measured by diffusion tensor imaging (DTI). This study examined the effect of an 8-month exercise intervention on WMI in children. Participants were 18 sedentary, overweight (BMI ≥85th percentile) 8- to 11-year-old children (94% Black), randomly assigned to either an aerob...
Article
Objective: Children who are less fit reportedly have lower performance on tests of cognitive control and differences in brain function. This study examined the effect of an exercise intervention on brain function during two cognitive control tasks in overweight children. Design and methods: Participants included 43 unfit, overweight (BMI ≥ 85th...
Article
Children with low aerobic fitness have altered brain function compared to higher-fit children. This study examined the effect of an 8-month exercise intervention on resting state synchrony. Twenty-two sedentary, overweight (body mass index ⩾ 85th percentile) children 8-11 years old were randomly assigned to one of two after-school programs: aerobic...
Article
Cognitive control is required for correct antisaccade performance. High antisaccade error rates characterize certain psychiatric disorders, but can be highly variable, even among healthy groups. Antisaccade data were acquired from a large sample of healthy undergraduates, and error rate was quantified. Participants who reliably made few errors (goo...
Chapter
Full-text available
Saccades are rapid eye movements that move the eyes to a location of interest. Regions within posterior parietal cortex (PPC) have consistently shown activation in brain imaging studies of saccades, ostensibly reflecting shifts of visual attention and the transformation of sensory input into motor commands. Saccades range from the most basic reflex...
Article
Full-text available
Functional imaging studies of emotional processing typically contain neutral control conditions that serve to remove simple effects of visual perception, thus revealing the additional emotional process. Here we seek to identify similarities and differences across 100 studies of emotional face processing and 57 studies of emotional scene processing,...

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