Curtis Andrew Dumond

Curtis Andrew Dumond
The Ohio State University | OSU · Division of Cardiac Surgery

Master of Science in Cardiovascular Perfusion

About

7
Publications
3,445
Reads
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18
Citations
Introduction
Skills and Expertise
Lung
Ventilation
Spirometry
Respiratory Physiology
Acute Lung Injury
Respiratory Mechanics
Mechanical Ventilation
Lung Transplantation
Pulmonology
Additional affiliations
December 2012 - July 2017
The Ohio State University
The Ohio State University
  • Division of Cardiac Surgery
  • Columbus, United States
Position
  • Laboratory Manager
Education
August 2017 - May 2019
Medical University of South Carolina
Medical University of South Carolina
Field of study
  • Perfusion
August 2011 - May 2017
The Ohio State University
The Ohio State University
Field of study
  • Radiation Therapy

Publications

Publications (7)
Pegylated-Catalase Is Protective in Lung Ischemic Injury and Oxidative Stress
Article
  • Jul 2020
Background Lung transplant ischemia-reperfusion injury (IRI) is typified by toxic metabolites and oxygen free radicals leading to worse graft function. Catalase is an enzyme involved in oxidative-stress detoxification. We hypothesize that direct delivery of highly concentrated polyethylene glycol-catalase (PEG-CAT) during normothermic ex-vivo lung...
A Novel Negative Pressure-Flow Waveform to Ventilate Lungs for Normothermic Ex Vivo Lung Perfusion
Article
  • May 2020
Ex vivo lung perfusion (EVLP) is increasingly used to treat and assess lungs before transplant. Minimizing ventilator induced lung injury (VILI) during EVLP is an important clinical need, and negative pressure ventilation (NPV) may reduce VILI compared with conventional positive pressure ventilation (PPV). However, it is not clear if NPV is intrins...
Figure 1: Perfusion Circuit. Components of the circuit are labeled. The...
Figure 2: Operating room and surgical instrument set-up. The surgical...
Figure 3: Prepare the 16 G portal vein cuff. Begin with a 16 G...
Figure 4: Midline incision. Make a midline incision from the xiphoid...
+2 Figure 13: Portal vein cuff and superior IVC cannulation. Cannulate the...
A Small Animal Model of Ex Vivo Normothermic Liver Perfusion
Article
Full-text available
  • Jun 2018
There is a significant shortage of liver allografts available for transplantation, and in response the donor criteria have been expanded. As a result, normothermic ex vivo liver perfusion (NEVLP) has been introduced as a method to evaluate and modify organ function. NEVLP has many advantages in comparison to hypothermic and subnormothermic perfusio...
Figure 1: Anatomical Illustrations. A. Anatomical illustration of the...
Figure 2: Anatomical Illustrations. Anatomical illustration of the rat...
Figure 3: Instrument Set-up. This figure demonstrates the instrument...
Figure 4: Operating Room Set-up. This figure demonstrates the operating...
+8 Figure 5: Trimming of Abdominal Hair. This figure demonstrates the...
Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
Article
Full-text available
  • Feb 2017
Major hepatic surgery with inflow occlusion, and liver transplantation, necessitate a period of warm ischemia, and a period of reperfusion leading to ischemia/reperfusion (I/R) injury with myriad negative consequences. Potential I/R injury in marginal organs destined for liver transplantation contributes to the current donor shortage secondary to a...
Figure 1 Cardiopulmonary bypass circuit is an open circuit in which...
Table 1 Comparison of mechanical circulatory support modalities 
Figure 3 Extracorporeal lung assist, Interventional Lung Assist, or the...
Figure 4 Only 15%-20% of donor organs meet standard criteria for lung...
Mechanical circulatory support in lung transplantation: Cardiopulmonary bypass, extracorporeal life support, and ex-vivo lung perfusion
Article
Full-text available
  • Jul 2015
Lung transplant is the standard of care for patients with end-stage lung disease refractory to medical management. There is currently a critical organ shortage for lung transplantation with only 17% of offered organs being transplanted. Of those patients receiving a lung transplant, up to 25% will develop primary graft dysfunction, which is associa...
Determination of Optimum Ventilation Strategy for Ex-Vivo Lung Perfusion: Comparing Negative and Positive Pressure Ventilation
Article
  • Apr 2015
Mechanical circulatory support in lung transplantation: Cardiopulmonary bypass, extracorporeal life support, and ex-vivo lung perfusion.
Article
  • Jan 2015
Abstract Lung transplant is the standard of care for patients with end-stage lung disease refractory to medical management. There is currently a critical organ shortage for lung transplantation with only 17% of offered organs being transplanted. Of those patients receiving a lung transplant, up to 25% will develop primary graft dysfunction, which i...

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