Cüneyt Tamer

• Doctor of Philosophy
• Ondokuz Mayıs University

Background Repurposing off-label drugs during epidemics or pandemics with unknown/known pathogens, particularly when their side effects and complications are already known, can be a strategic approach, as seen during the COVID-19 pandemic. Developing surrogate in vitro experimental models (passage-to-passage), which mimic epidemic/pandemic-like tra...

Maedi-Visna is a slowly progressive infection of sheep that affects the respiratory and nervous systems and causes significant yield losses worldwide. This study was conducted to assess the seroprevalence of Maedi-Visna infection in sheep across several provinces in the Central Black Sea region of Türkiye, namely Samsun, Sinop, Ordu, Giresun, Amasy...

Infectious pancreatic necrosis virus (IPNV) causes economic losses with a highly variable mortality rate worldwide, especially in rainbow trout. The virus has a double-stranded bi-partite RNA genome designated segment A and B. New complete genome sequences of nine rainbow trout isolates from Turkey were determined and subjected to phylogenetic anal...

Virüs genomlarının çevrilmemiş bölgelerinin (UTR'ler), mRNA'ların çekirdek dışına taşınması ve translasyon verimliliği dahil olmak üzere gen ifadesinin transkripsiyon sonrası düzenlenme-sinde önemli roller oynadığı bilinmektedir. Birçok hastalığın moleküler profilinin çıkarılması, mRNA'ların çevrilmemiş bölgelerinin hastalığın ilerlemesinde ve yatk...

Aquareovirus A (AqRV A) has been known to cause low or intermediate diseases among various salmon species and mollusks. Additionally, Piscine orthoreovirus (PRV), divided into subtypes PRV-1, PRV-2 and PRV-3, has been reported in rainbow trout, coho salmon and Atlantic salmon. In this study, we investigated the presence of these aquatic reoviruses...

Background & objectives: West Nile virus (WNV) is transmitted by a mosquito-borne virus whose natural reservoir is birds. Humans and horses are considered accidental hosts. Even if the vast majority of WNV infections in humans have asymptomatic or mild disease settings, serious neurological disorders with lethal outcomes can also be observed in ar...

Lumpy Skin Diseases Virus (LSDV), belonging to the capripoxvirus genus of the Poxviridae family, causes significant infections in cattle, especially in African and Middle East countries. LSD is an arboviral disease that spreads with bloodsucking flies as the primary source of infection. However, in experimental studies, nucleic acid belonging to th...

Current evidence have now demonstrated that SARS-CoV-2 infects a wide array of mammalian animals; however, the full range of hosts and the viral circulation in companion animals remains to be clarified. In this context, as no such evidenced cases have been reported from Turkey, we aimed to screen for SARS-CoV-2 nucleic acid in housed dogs and cats...

Background The canine parvovirus, with its many variants, is responsible for a pivotal and common viral infection affecting millions of dogs and other carnivore species worldwide, particularly the wild ones, which are considered as the main reservoir hosts. To that end, this study investigated the presence of canine parvovirus (CPV) in red foxes (V...

Mavidil virusu (MDV) Avrupa’da önemli verim kayıplarına sebep olan vektörlerle nakledilen ve özellikle koyunlarda teratojenik etkiye sahip bir virustur. Bu çalışma Orta Karadeniz bölgesinde yer alan Samsun, Sinop, Ordu, Giresun ve Amasya illerinde MDV’nin seroprevalansını araştırmak amacıyla yapıldı. Her bir ilden 80 adet olmak üzere toplam 400 ade...

Two pandemics over the first two decades of the 21 st century have shown that viruses with epidemic and pandemic potentials constitute a major threat to human health due to the lack of effective antivirals. Developing new antivirals and treatment strategies is also as important as vaccines play a crucial role in the first line of preventing viral i...

Lymphocystis disease viruses (LCDVs) are viruses that infect bony fish which has been found in different locations across the globe. Four virus species have been classified by the International Committee on Taxonomy of Viruses (ICTV), despite remarkable discrepancies in genome size. Whole genome sequencing and phylogenetic analysis of LCDVs from wi...

Tick-borne encephalitis (TBE) is an endemic viral zoonotic disease in many regions of Eurasia. In this study, whole blood, serum samples and the hard ticks collected from a variety of ruminant species (cattle, goat and sheep) in the middle Black Sea region of Turkey were investigated for the presence of RNA and IgG antibodies against Tick-borne enc...

Viral diseases of fish cause significant economic losses in the aquaculture industry. Viral haemorrhagic septicemia virus (VHSV) is one of the most important viral diseases that affects more than 80 fish species. Detection of the disease, especially in the field, is critical to managing disease prevention and control programmes. Recombinase pol-yme...

Infectious pancreatic necrosis (IPN) is a highly contagious disease causing high mortality in juvenile trouts. Since there is no effective way to treatment against IPNV, early diagnosis and prevention play an important role in combating the disease. The different types of IPNV vaccines (inactive, live, recombinant, DNA, etc) have been produced from...

Infectious pancreatic necrosis (IPN) is a highly contagious disease of young salmonid fish and is one of the most severe economic diseases in aquaculture. In Turkey, an increase in infectious pancreatic necrosis virus (IPNV) outbreaks in freshwater rainbow trout have been reported in recent years. This study aimed to analyze the VP2 gene from recen...

The aim of this study was to investigate the presence of caprine herpes virus-1 (CpHV-1) and bovine herpes virus-1 (BoHV-1) in 269 goat sera collected from small-scale family farms located in six provinces within the Black Sea region of northern Turkey. The overall seropositivity for alpha-herpesvirus in the native goats was found as 19.33% using B...

Infectious Pancreatic Necrosis Virus (IPNV) and Viral hemorrhagic septicemia virus (VHSV) cause significant losses in the aquaculture industry. There have been few reports of the use of screening rainbow trout for antibodies against IPNV and VHSV as an epidemiological tool. Several ELISAs using a whole virus or recombinant IPNV and VHSV proteins ha...

West Nile virus (WNV) is a mosquito‐borne virus of a re‐emergence importance with a wide range of vertebrate hosts. Granted, it causes asymptomatic infection, but fatal cases and neurologic disorders were also recorded, especially in humans, horses and some exposed birds. The virus is globally spread and birds are considered an amplifying and reser...

Infectious pancreatic necrosis (IPN) is a highly contagious disease causing high mortality in juvenile trouts. Since there is no effective way to treatment against IPNV, early diagnosis and prevention play an important role in combating the disease. The different types of IPNV vaccines (inactive, live, recombinant, DNA, etc) have been produced from...

Bovine parainfluenza virus‐3 (BPIV‐3), also known as bovine respirovirus 3, causes serious respiratory infection in ungulates, often involving other pathogens, such as viruses, bacteria and mycoplasmas. In this study, we evaluated antibody titers against virus genotypes A (BPIV‐3a) and C (BPIV‐3c). We conducted a serological survey and comparison a...

The aquatic virus, infectious pancreatic necrosis virus (IPNV), is known to infect various farmed fish, in particular salmonids, and is responsible for large economic losses in the aquaculture industry. Common practices to detect the virus include qPCR tests based on specific primers and serum neutralization tests for virus serotyping. Following th...

Marek's disease (MD) is an important disease of avian species and a potential threat to the poultry industry worldwide. In this study, 16 dead commercial chickens from flocks with suspected MD were necropsied immediately after death. Pathological findings were compatible with MD, and gallid alphaherpesvirus 2 was identified in PCR of spleen samples...

Viral haemorrhagic septicaemia (VHS) is a serious disease of finfish with a high mortality rate (70%) worldwide. It is caused by infectious viral haemorrhagic septicaemia virus (VHSV). No commercial vaccine is available against VHSV so far. In the present study, we aimed to develop a sustainable recombinant subunit vaccine against a local isolate o...

İnsanoğlu, tarih boyunca çeşitli mikroorganizmalar tarafından meydana getirilen enfeksiyonlardan muzdarip olmuş ve maalesef olmaya devam etmektedir. Bu enfeksiyonlardan bazıları sınırlı bir bölge de hastalıklar meydana getirirken, bazıları ise ciddi epidemilere hatta dünyayı etkisi altına alan pandemilere neden olmuştur. Son olarak Coronaviridae ai...

Infectious pancreatic necrosis virus (IPNV) and viral haemorrhagic septicaemia virus (VHSV) are two of the major viral threats faced by the aquaculture industry in Turkey. The aim of our study was to investigate the pathogenicity of two Turkish viral strains isolated locally from the Bolu VHSV strain (Accession number: KM972678.1) and the HAH‐4 IPN...

Bovine respiratory disease (BRD) is a huge economic burden on the livestock industries of countries worldwide. Bovine respiratory syncytial virus (BRSV) is one of the most important pathogens that contributes to BRD. In this study, we report the identification and first isolation, with molecular characterization, of a new BRSV strain from lung spec...

Özet: İnsanoğlu yaklaşık bir asır sonra etkisini tüm dünyada hissettiren viral bir pandemi ile karşı karşıya kalmıştır. Çin’de 2019 yılı Aralık ayında varlığı tespit edilen ve son olarak Severe Acute Respiratory Syndrome coronavirus 2 (SARSCoV2) olarak adlandırılan yeni insan coronavirüs salgını, birkaç ay gibi kısa bir sürede pandemi seviyesine u...

This study aimed to investigate the presence of bovine herpesvirus 1 by molecular techniques in two cases of respiratory disease in beef cattle, reported from Amasya Province of Turkey in 2018. Nasal swab and lung tissue samples were taken. The presence of bovine herpesvirus-1 (BoHV-1) was confirmed by the PCR method using glycoprotein B (gB) gene-...

This study was conducted in Samsun Province of Turkey to investigate the serological status of domesticated water buffaloes for both Crimean-Congo Hemorrhagic Fever (CCHF) and Lumpy Skin Disease (LSD). Serum was collected from a total of 272 water buffaloes from different age groups and both genders; of the total, 48.1% had been vaccinated against...

Infectious pancreatic necrosis (IPN), viral hemorrhagic septicemia (VHS) and infectious hematopoietic ne-crosis (IHN) are the most significant viral diseases of salmonid species. This study examined the seroprevalence of infectious pancreatic necrosis virus (IPNV), viral hemorrhagic septicemia virus (VHSV) and infectious hematopoietic necrosis viru...

Infectious pancreatic necrosis (IPN), viral hemorrhagic septicemia (VHS) and infectious hematopoietic necrosis (IHN) are the most significant viral diseases of salmonid species. This study examined the seroprevalence of infectious pancreatic necrosis virus (IPNV), viral hemorrhagic septicemia virus (VHSV) and infectious hematopoietic necrosis virus...

Bovine parainfluenza 3 virus (BPI3V)is one of the most important respiratory pathogens and a leading cause of serious respiratory illnesses in cattle, both independent of and in connection with other pathogens involved in the bovine respiratory disease complex (BRDC). In this study, we aimed to identify the historical circulation of genotype C bovi...

A respiratory disease outbreak on a cattle farm in northern Turkey produced respiratory tract symptoms and severe pneumonia symptoms in 20 calves. Eight calves died, and a lung specimen from one carcass was analysed for bacteria and for viruses of the Bovine respiratory diseases complex. Bacteriological analysis was negative, but antigen detection...

Effect of Apigenin on Herpes Simplex Virus-1 Titer

West Nile virus (WNV) is an important arthropod-borne pathogen and a leading cause of morbidity and mortality in human and animal populations in many parts of the world. The presence of WNV in Turkey has been reported in various studies during the last 15 years. In this study, 1500 horse serum samples collected from Ardahan Province in Northeastern...

Aim: This study was designed and implemented at University of Khartoum to investigate the effect of camel milk mixed with camel urine and camel urine alone on hematological parameters of albino rats. Materials and Methods: 30 Wister Albino rats of both sexes weighing 85-105 g were brought and divided into 3 groups. Group 1 (control group) received...

The aim of this study was to investigate the prevalence and distribution patterns of LSDV infections in the provinces of northern Turkey, and to detect the factors influencing the epidemiology of LSD virus infections (age, breed, season, climate, geography, population dynamic, animal movement), as well as to assess the diagnostic value of the sampl...

Hayvancılıkta reprodüksiyon sorunları işletmelerin mücadele edeceği önemli sorunlardan birisi olarak kabul edilir ve erken teşhisi edilmesi önem taşır. Teratojen ajanlar ise, gebelik döneminde gelişimsel bozukluklara neden olarak reprodüktif sorunlar oluşturan önemli etkenlerdendir. Enfeksiyöz teratojen ajanlar içerisinde sınıflandırılan viral etke...

Foot-and-mouth disease (FMD) is one of the major endemic trans-boundary livestock diseases of so-cio-economic importance in Turkey and worldwide. Goats constitute the third largest susceptible population of domestic livestock in Turkey. FMD surveillance and control strategies in the country largely ignore small ruminants, known to be critical in th...

Bovine viral diarrhea virus (BVDV) and Bovine herpes virus type-1 (BHV-1) are economically important pathogens leading to critical health problems for widespread ruminant populations worldwide. This study was conducted in order to update the seroprevalence of both viruses in non-vaccinated ruminant breeding enterprises in the Black Sea Region of Tu...

In February 2016, a local respiratory disease outbreak with two fatalities was reported in Samsun, Turkey. A non-cytopathic bovine viral diarrhea virus (ncp-BVDV) was identified from the organ and leucocyte samples of dead juvenile heifers using RT-PCR with specific primers for the NS2/3 gene coding region. The NS2/3 gene of BVDV was sequenced and...

There is a lack of information about the seroprevalence of pestiviruses in indigenous and composite goat breeds in Turkey. In this study, blood samples randomly collected from different domestic goat breeds (Anatolian black goat, Maltese and Saanen). The material consisted of 368 domestic goats, including 121 Anatolian black breeds, 125 Maltese bre...