Csanad Botond Penzes

Csanad Botond Penzes
Eötvös Loránd University · Laboratory of Colloid and Supramolecular Systems

Doctor of Philosophy

About

10
Publications
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166
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Introduction
Csanad Botond Penzes currently works as a technical consultant at Interkerám Ceramic Basic Material Manufacturing and Trading Co. Ltd.. in Kecskemét. Csanad did research in Polymer Chemistry and Surface Chemistry at Eötvös Loránd University.

Publications

Publications (10)
Article
Biodegradable polylactic/glycolic acid copolymers are widely used as colloidal drug delivery systems. PLGA nanoparticles were prepared using non-ionic, PEO-containing block copolymer (Pluronic) and charged polymeric (PEI) surface modifiers. Physicochemical properties such as size, size distribution, zeta potential, surface composition, and colloid...
Article
Electrochemical and mechanical properties of ruthenium films electrodeposited on gold have been investigated in aqueous perchloric acid solutions. Cyclic voltammograms recorded at slow sweep rates in rotating disk experiments were highly asymmetric with respect to the electrode potential axis, and a negative current could be observed even during th...
Article
Surface behaviour of mixed monolayers of DPPC and mycolic acid as a specific membrane component of Mycobacterium tuberculosis were studied by Langmuir-balance technique. Additivity analysis of the surface pressure–area isotherms showed that mixed layers are expanded at higher temperature (36 °C) while negative excess surface areas were obtained dep...
Article
The antibacterial behavior of cationic polyelectrolytes is studied using model membrane experiments and in vitro bacterial investigations. The molecular interaction with lipid films is evaluated by the degree of penetration of the polymers into Langmuir monolayers of neutral or negatively charged lipids. The polymer/lipid interaction results in str...
Article
Full-text available
Isoniazid (INH) is a first line drug for treatment of the widespread deadly disease caused by Mycobacterium tuberculosis. Peptide conjugate of INH was designed and synthesised for targeted and receptor mediated cellular uptake of INH. Chemical composition, hydrophobicity (n-octanol/water partition coefficient), and membrane affinity (using a Langmu...
Article
Biodegradable polyesters such as poly(lactic-co-glycolic acid) copolymers (PLGA) are preferred materials for drug carrier systems although their surface hydrophobicity greatly limits their use in controlled drug delivery. PLGA thin films on a solid support blended with PEG-containing compound (Pluronic) were used as model systems to study the inter...
Conference Paper
Tuberculosis is a major problem throughout the world causing 1.9 million deaths annually, and induces a major global public health problem. The pathogen responsible for the disease is Mycobacterium tuberculosis. Drug candidates expected to be specific inhibitors of dUTPase an essential enzyme of Mycobacterium tuberculosis were identified in silico....
Article
Tensiometry, sum-frequency vibrational spectroscopy, and atomic force microscopy were employed to assess the cell penetration ability of a peptide conjugate of the antituberculotic agent isoniazide. Isoniazide was conjugated to peptide (91)SEFAYGSFVRTVSLPV(106), a functional T-cell epitope of the immunodominant 16 kDa protein of Mycobacterium tuber...
Conference Paper
Full-text available
Tuberculosis remains a major problem throughout the world causing large number of deaths, more than that from any other single infectious disease [1]. The treatment of the chronic inflammatory caused by Mycobacterium tuberculosis (Mtb) requires prolonged chemotherapy often associated with unwanted side effects and developing resistant bacterium str...

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