Cristian Catalin Gavat

GRIGORE T. POPA University of Medicine and Pharmacy, 16 Universitatii Street Iasi 700115 Romania · Biomedical Sciences Department, Faculty of Medical Bioengineering

Ibuprofen is a prominent member of the group of non-steroidal anti-inflammatory drugs (NSAIDs), with good anti-inflammatory action, a very effective analgesic, with increased antipyretic effect. The aim of this research was to exactly quantify pure Ibuprofen content in tablets of a pharmaceutical, by a spectrophotometric analysis method in the Visi...

Sodium valproate is a established antiepileptic drug of first choice, primarily used to treat epilepsy, but also bipolar disorder and prevent migraine headaches. Valproate increases concentrations of gamma-aminobutyric acid in the brain, due to inhibition of enzymes responsible for the catabolism of gamma-aminobutyric acid. Main goal of this resear...

The purpose of conducted study was to determine which of the different types of statins ensure a better control of biological markers in diabetic patients and which of the lipid molecules studied, could be a first choice of lipid-lowering therapy in people suffering from diabetes. The measurement of blood glucose levels depending on type of statin...

Ascorbic acid is a water-soluble vitamin provided with strong antioxidant action, that fulfills an important immune protective role of the body against infections and prevents various cancers appearance. The main goal of this study was to exactly quantify pure ascorbic acid in tablets of two pharmaceuticals. Proposed objective consisted in improvem...

The aim of this research was to exactly quantify pure sodium metamizole from tablets , using a brand new and developed spectrophotometric analysis method in Visible range (VIS). Main objectives consisted in comparing Sodium Metamizole found content with the stated amount of pure active substance declared by pharmaceutical company, according to the...

A spectrophotometric method in visible range measuring the active compound content of pharmaceutical tablets was developed and proposed to be validated and applied. The analysis method was highly precise (presenting the relative standard deviation values within the accepted range of values, RSD ≤ 5%), and highly accurate (presenting the average rec...

The aim of this study was to evaluate the main metabolic changes in the case of hepatitis B virus (HBV) / human immunodeficiency virus (HIV) coinfection. A retrospective study, on 482 HIV infected patients was assessed, at Iasi Regional HIV-AIDS Center Iasi, between 2000-2014. Subjects were divided into 2 groups, according to the presence or absenc...

The aim of this research was to exactly quantify the pure sodium metamizole content from pharmaceutical tablets, by using a spectro-photometric analysis method in visible range. The method applied has been subjected to a validation protocol which consisted in analyzing the following parameters: linearity of the method, limit of detection (LD) and l...

The objective was to use of a minimum number of ISI (International Sensitivity Index) to determine the International Normalized Ratio (INR). This specific calibration methods allowed to calculate ISI for all other thromboplastines comparative with the reference thromboplastine. Bigger values than 1 show a decrease sensitivity, as compared with the...

Ibuprofen is a prominent member of the group of non-steroidal anti-inflammatory drugs (NSAIDs), with good anti-inflammatory action, a very effective analgesic, with increased antipyretic effect. The aim of this research was to exactly quantify pure Ibuprofen content in tablets of a pharmaceutical, by a spectrophotometric analysis method in the Visi...

The purpose of conducted study was to determine which of the different types of statins ensure a better control of biological markers in diabetic patients and which of the lipid molecules studied, could be a first choice of lipid-lowering therapy in people suffering from diabetes. The measurement of blood glucose levels depending on type of statin...

The aim was to exactly quantify the amount of pure ketoprofen of a pharmaceutical by a new, developed ultraviolet (UV) spectrophotometric method. The maximum absorption wavelength was determined to be at λ = 254 nm for a ketoprofen alcoholic standard solution of 1.4 µg/mL. The applied method was statistically validated. The amount of pure ketoprofe...

Reactive dyes are synthetic organic compounds used on a wide scale in textile industry, for painting materials of different types and compositions (e.g. 100% cotton, wool, natural satin, viscose, synthetic fibres). Reactive dyes are solid compounds (powders) completely water soluble at normal temperature and pressure conditions. Their structures co...

and Holt Romania Foundation REVISTA DE CERCETARE SI INTERVENTIE SOCIALA is indexed by ISI Thomson Reuters-Social Sciences Citation Index (Sociology and Social Work Domains) Working together www.rcis.ro expert projects publishing A retrospective study was made on 195 institutionalized elderly people and was carried out between 2002-2006 in three so...

Textile dyes have been reported of causing various stages of contact dermatitis. Reactive dyes are widely applied in dyeing cellulose fiber based textiles (100% cotton), skin fibers (hemp, flax), regenerated cellulose (cellulose acetate, viscose), protein fibers (natural silk, wool). The human body comes in contact daily with such compounds. This a...

Ibuprofen is a prominent member of the group of non-steroidal anti-inflammatory drugs (NSAIDs), with good anti-inflammatory action, a very effective analgesic, with increased antipyretic effect. The aim of this research was to exactly quantify pure Ibuprofen content in tablets of a pharmaceutical, by a spectrophotometric analysis method in the Visi...

Ibuprofen is a prominent member of the group of non-steroidal anti-inflammatory drugs (NSAIDs), with good anti-inflammatory action, a very effective analgesic, with increased antipyretic effect. The aim of this research was to exactly quantify pure Ibuprofen content in tablets of a pharmaceutical, by a spectrophotometric analysis method in the Visi...

The paper describes the photochemical stability of a commercial triphenodioxazine dye (Reactive Blue_204) linked onto a cotton fabric. Preliminary studies have shown that as a result of irradiation, the dye and its photodegradation products can pass directly onto the skin under conditions that mimic human perspiration and cause side-effects. The co...

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Certificate of Course Completion. Nature Masterclasses. SPRINGER NATURE

This is to certify that: Cristian-Catalin Gavat has completed the online course for the Wiley Reviewer Academy.

Researcher Academy Certificate of Excellence. This certifies that. Cristian-Catalin Gavat has successfully completed every module within the Certified Peer Reviewer Course - Elsevier

Certificate of Completion for successfully completing the online course ACS Reviewer Lab, demonstrating their understanding on the principles of high quality of peer review including reviewer ethics, instructions for reviewers, and tools and components for writing a constructive review.

Ascorbic acid is a water-soluble vitamin provided with strong antioxidant action, that fulfills an important immune protective role of the body against infections and prevents various cancers appearance. The main goal of this study was to exactly quantify pure ascorbic acid in tablets of two pharmaceuticals. Proposed objective consisted in improvem...

The aim of this research was to exactly quantify pure sodium metamizole from tablets , using a spectrophotometric analysis in Visible range. The method applied has been subjected to a validation protocal which consisted in analyzing the following parameters: linearity of the method, detection limit (LD) , quantitation limit (LQ), Sandell’s sensitiv...

The aim of this research was to exactly quantify pure sodium metamizole from tablets , using a spectrophotometric analysis in Visible range. The method applied has been subjected to a validation protocal which consisted in analyzing the following parameters: linearity of the method, detection limit (LD) ,quantitation limit (LQ). Following actual do...

Reactive dyes are synthetic organic compounds used on a wide scale in textile industry, for painting materials of different types and compositions (e.g. 100% cotton, wool, natural satin, viscose, synthetic fibres). Reactive dyes are solid compounds (powders) completely water soluble at normal temperature and pressure conditions. Their structures co...

The purpose of conducted study was to determine which of the different types of statins ensure a better control of biological markers in diabetic patients and which of the lipid molecules studied, could be a first choice of lipid-lowering therapy in people suffering from diabetes. The measurement of blood glucose levels depending on type of statin...

This study assessed the medication used in type 2 diabetes treatment, depending on the glycaemia level and set out the oral anti-diabetics which are recommended, in three study stages: admission, hospitalization and discharge. Eighty patients were selected and diagnosed with diabetes mellitus 2 type, who were registered in the diabetes and nutritio...

Textile dyes have been reported of causing various stages of contact dermatitis. Reactive dyes are widely applied in dyeing cellulose fiber based textiles (100% cotton), skin fibers (hemp, flax), regenerated cellulose (cellulose acetate, viscose), protein fibers (natural silk, wool). The human body comes in contact daily with such compounds. This a...

A retrospective study was made on 195 institutionalized elderly people and was carried out between 2002-2006 in three social care centers from Galati county: “Sf. Spiridon” retirement home (A), “Stefan cel Mare” social care center (B) and Medical-social center (C). The aim of this study is to find out the real social life conditions of institutiona...

Ergonomic devices are often designed to provide more comfort and to increase productivity but they can also help avoid pain and specific injuries. The ergonomic design of a computer keyboard needs expertise in ergonomics and bio-mechanics. The existence of a large category of typists with slow typing skills, visually searching the seemingly random...

The influence of ultraviolet irradiation of different doses (λ > 300 nm) on the structural and color modifications of cotton fabrics painted with four different azo-triazine dyes (Reactive Yellow 143, Reactive Orange 13, Reactive Red 183, and Reactive Red 2) was studied. High irradiation doses up to 3500 J cm–2 led to changes in the dyes structures...

Bioreactive polysaccharides have been most commonly used as drugs or drug delivery systems. The present paper describes the biological activity of some artificial and natural polyanionic polysaccharides. Results regarding oxidized cellulose and carboxymethylcellulose modified with benzocaine or N - hydroxy - 3,4 - dihydroxybenzamide (Didox) complet...

Abstract AIM: To evaluate immune system response, skin and hepatic reactivity in Swiss mice after retro auricular local administration of two textile dyes. MATERIAL AND METHODS: On 3 groups of white Swiss mice: group I (Cibacron Yellow F-4G), group II (Cibacron Orange P-2R) and control group (DMSO dimethylsulfoxide), substances were applied on lef...

Abstract Reactive Red 183, Reactive Red 2 and Reactive Blue 204 (red dye, green dye and blue dye) are three reactive dyes frequently used in textile industry. In some atmospheric conditions ( high temperature, perspiration, pH values, UV/IR radiations), some quantities of these hydrolyzed dyes, could pass from textile clothes directly into the huma...

EXPERIMENTAL RESEARCHES ON EFFECTS OF TWO REACTIVE DYES, REACTIVE RED 183 AND REACTIVE YELLOW 143, ON IMMUNE SYSTEM OF SWISS MICE. Abstract. Reactive Red 183 and Reactive Yellow 143 are two reactive dyes frequently used in textile industry, for textile textile cotton dyeing fabrics. These dyes attaches on cotton fiber through powerful covalent boun...

SPECTROSCOPY ANALYSIS METHOD OF TWO REACTIVE DYES USED IN TEXTILE INDUSTRY (Abstract): Reactive Blue 204 and Reactive Red 183 are two reactive dyes frequently used for textile painting and printing. Before using in chemical laboratory analysis, these reactive dyes must be evaluated through validation methods which consists of linearity, stability o...

EXPERIMENTAL STUDY REGARDING THE INFLUENCE OF REACTIVE DYES, REACTIVE BLUE 204 AND REACTIVE RED 183 UPON SOME IMMUNOLOGICAL PARAMETERS (Abstract): Reactive Blue 204 and Reactive Red 2 are two reactive dyes frequently used in textile industry. In some atmospheric conditions, high temperature, perspiration , pH values UV, IR radiations, they could pa...

CV LIST OF Recent Papers: Cristian-Catalin Gavat

SPECTROSCOPY ANALYSIS OF REACTIVE RED 2 DYE (Abstract): Reactive Red 2 is a reactive red dye used for textile painting and printing. Before using in chemical laboratory analysis, this reactive dye must be evaluated through validation methods, which consists of: linearity, specificity, precision, accuracy and stability of solutions. The aim of this...

WATER QUALITY !N IASI COUNTY BETWEEN 2003-2006 RELATED TO POPULA­TIION'S HlDRICAL MORBITY (Abstract): we have analyzed the water distributed in Iasi county, between years 2003 and 2006, for the chemical and bacteriological quality and simulta­neously we've followed the morbidity of some hydric diseases (hepatitis with virus A, bacillary dysentery,...

The body mass index (BMI) shows a rate of 17.4% patients suffering from first degree fatness and 56.5% from second degree fatness. The frequency of the illness increases with age, the differences established being statistically important for a p of 0.001. 45.6% persons were diagnosed with HTA, with differences statistically important at a p of 0.01...