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Publications (81)
Introduction
It is well known that cardiovascular diseases are the leading cause of death worldwide. In Romania in 2015, cardiovascular diseases led to 153.953 deaths, representing 59.3% of deaths from all causes. Most people in Romania today have an unhealthy lifestyle, characterised mainly by a poor nutritious diet, low physical activity and a la...
Heart failure (HF) presents an increasingly significant problem as the population ages. The cause of HF plays a significant role in determining treatment options and outcomes. It is worth noting that several studies have identified gender disparities in both morbidity and mortality, which may suggest differing causes of HF. The purpose of this rese...
(1) Background: Heart failure (HF) remains one of the most frequent public health problems, with high mortality and hospitalization rates. Identifying an indicator with a prognostic role in patients with HF could represent a salutary solution in the future, as it could identify patients with a negative prognosis. Thus, our study focused on mean pla...
Funding Acknowledgements
Type of funding sources: Other. Main funding source(s): European Union’s Horizon 2020.
Background/Introduction
According to WHO cardiovascular diseases (CVDs) are the leading cause of mortality. Heart attacks and strokes account for more than four out of every five CVD fatalities. Early identification of patients at risk t...
Purpose
Despite all medical efforts and discoveries, heart failure (HF) remains one of the most important and common public health problems, with high mortality and hospitalization rates, due to decompensation of HF. In the present study, we aimed to identify a predictive factor through which we can evaluate the risk of readmission and mortality in...
72 yo male, presents for abdominal pain and motor deficiency of the left upper limb. Clinical examination reveal severe general condition, left brachial hemiparesis, right arm blood pressure (BP) 240/120 mmHg, left arm BP 210/100 mmHg, heart rate (HR) 110 bpm, arrhythmic, abdominal pain at superficial palpation, without other abnormalities. Biologi...
Purpose. The present study aim to identify whether an unhealthy lifestyle, defined as active smoking and hyper sodium diet, leads to a higher likelihood of readmission of patients with heart failure (HF) during the vulnerable period or to an increased risk of in-hospital mortality and one year mortality. The vulnerable period for patients with hear...
Objective. Demonstrating cardiovascular injury amoung a group of female patients suffering from anorexia, compared to a similarly-aged group of women with body mass within the normal range. Materials and methods. Clinical, biological and paraclinical parameters were determined in the two patient groups: Group A, consisting of 39 patients suffering...
The pulmonary embolism (PE) represents a medical condition with increasing incidence. The various clinical forms of PE have different prognosis, related to the presence of markers of right ventricle (RV) dysfunction (biochemical or imagistic). Material and method. In this study we included 82 consecutive patients with intermediate-high risk PE, ass...
There is a growing use of trans-radial catheterisation for angiography and percutaneous interventions. The advantages of trans-radial over traditional femoral access include a decrease in the incidence of access site bleeding complications and improved patient comfort and recovery. Ensuring short haemostasis, which controls arterial bleeding after...
Right distal transracial approach in the anatomical snuff box could reduce the probability of radial artery occlusion. Also, that approach allows a more comfortable hand position, especially in obese patients. We prospectively evaluated right distal transracial approach (DTRA) in patients treated trans-radially. Materials and methods: Prospective,...
Rationale:
Coronary chest pain is usually ischemic in etiology and has various electrocardiographic presentations. Lately, it has been recognized that myocardial bridging (MB) with severe externally mechanical compression of an epicardial coronary artery during systole may result in myocardial ischemia. Such a phenomenon can be associated with chr...
The objective of the study is to assess the efect of thrombolitic therapy on clinical prognostic markers in patients with intermediate-high risk pulmonary embolism compared to clasic therapy, and also the assessment of the bleeding risk associated with thrombolitic therapy.
Material and methods. We included 82 consecutive patients with intermediate...
Introduction. Right ventricle was long time considered to be the „insignificant chamber“, while recent studies
demonstrate that the right ventricle dilatation and sistolic dysfunction, is associated with increased cardiovascular
mortality and morbidity. This finding might be explained by the effect of thyroid hormone on increasing the total
blood v...
A myriad variety of therapeutic agents or chemical substances can induce either a transient or persistent increase in blood pressure, or interfere with the blood pressure-lowering effects of antihypertensive drugs. The mechanism of drug-induced hypertension are multiple, including sodium retention and extracellular volume expansion, act...
Age is an important prognostic factor in the outcome of acute coronary syndromes (ACS). A substantial percentage of patients who experience ACS is more than 75 years old, and they represent the fastest-growing segment of the population treated in this setting. These patients present different patterns of responses to pharmacotherapy, namely, a high...
Refractory angina pectoris (RAP) is a clinical problem, frequently encountered in the elderly, associated with high health-care costs. Until recently, the goal of RAP treatment aimed at improving the quality of life (QoL) because it was thought that mortality rates were not different between stable angina pectoris and RAP. Our purpose was at determ...
This paper examines the home monitoring system used in our Department of Cardiology in the Future Internet Social Technological Alignment in Healthcare (FI-STAR) project - a project focused on secondary prevention in cardiology (www.fi-star.eu). The system used is composed of bluetooth capable medical devices that collect vital parameters though Ca...
Thyroid pathology is rarely involved in the pathogenesis of sudden death in young people. We report here the cases of two young patients with decreased levels of thyroid hormones whose death was caused by an increased thrombotic status, with venous thrombosis and pulmonary thromboembolism. In both cases the thyroid pathology was not considered as t...
Objective: It is well known that NTproBNP is useful in diagnosis of heart failure. This is a pilot study that aims to study the importance of NTproBNP in patients without heart failure(but with conditions at risk of developing heart failure)for guiding treatment to prevent heart failure. Design and method: We included 164 patients who were present...
Objective: The thrombolytic therapy in patients with intermediary risk pulmonary embolism is a debated subject. According to the ESC Guidelines for the Management of Acute Pulmonary Embolism (2014) the thrombolytic therapy in patients with intermediary - high risk pulmonary embolism (defined as PESI score >85, echocardiography signs of RV dysfuncti...
Objective: Particular case of hypertension-case report Design and method: We report the case of 74 year old women, permanently hospitalized to a chronic diseases hospital, with Alzheimer disease and stroke in history, presented to our emergency unit, with one week elevated BP values around 180 / 100mmHg. At presentation the patient was obtundation,...
Objective: The purpose of our study was to analise the blood pressure (BP) profile in patients with acute pulmonary edema (APE)/ acute heart failure (AHF). Design and method: We analised 2 groups of 50 patients. The first group included patients hospitalized for APE/AHF symptoms and BP > 180 mmhg. The second group included patients who attended the...
Objective: Systolic blood pressure (SBP) measured at hospital admission is an important prognostic factor in predicting the risk of death during hospitalization and at 3 months after discharge in patients with preserved left ventricular function and in those with systolic dysfunction. Design and method: We conducted a prospective study on a sample...
Background: Advanced disease prevention solutions using telemedicine are vital for the future in order to decrease the burden produced by the cardio-vascular diseases. This solutions need to ensure more accessibility, high performance and good data privacy. Material and Method: Study groups consist of 48 acute myocardial infarction patients: 24 hom...
Increasing costs of treatments have led to the apparition of the medical tourism. Patients in high-income countries seek to solve their health problems in developing countries where the cost of medical treatment is much lower. This cost difference has led to the medical tourism industry that is currently estimated with an annual growth rate of abou...
The presence of peripheral arterial disease (PAD) is associated with higher cardiovascular morbidity and mortality, regardless of gender or its clinical form of presentation (symptomatic or asymptomatic). PAD is considered an independent predictor for cardiovascular mortality, more important for survival than clinical history of coronary artery dis...
Cavernous haemangioma (cavernoma) is a benign vascular lesion, exceptionally located in cauda equina. We report a case, diagnosed and operated in the Department of Neurosurgery from Pitesti County Emergency Hospital, of a 60-year-old woman with history of lumbar region distress, who presented with low back pain, paravertebral muscle contracture, an...
Background: Venous thromboembolism represents the third cause of cardiovascular disease after coronary artery disease and stroke with remarkable complications and high recurrence rate. Up to 50% of the new cases of venous thromboembolism are idiopathic, and patients with this condition require special care and follow up. Thrombophilic factors have...
Venous thromboembolism is a manifest disease that includes deep vein thrombosis and pulmonary embolism. It is the third most common cardiovascular disorder after coronary artery disease and stroke.
This paper mainly intends to pursue the manner in which spatial distribution of the medical infrastructure is correlated to the hospitalized patients' flow having as diagnosis Acute Myocardial Infarction. In this context, we will describe territorial distribution elements for the hospital beds by various medical specialties as well as the way in wh...
The authors present various means of implementing obligation ethics at workplace in the the medical system. In addition, the study presents the results of a research regarding the perceptions of nurses over the obligations involved by the contract between the employer and its employees. A series of behavior norms and types of regulations' will be m...
A priority of medical university education is that to train students to work on completing their studies in university research departments of medicine or university hospitals. The aim of this work was to provide students from several universities of medicine methods used to analyze geographic features of patients with acute myocardial infarction h...
Heart failure patients present an important thrombo-embolic risk, including symptomatic or silent peripheral arterial embolism, pulmonary embolism and stroke. Patients in sinus rhythm that have concomitant depressed (<35%) left ventricular ejection fraction have a 4% rate of embolic events. Several prospective randomized trials of anticoagulation i...
Aortic stenosis (AS) is the most frequent valvular heart disease encountered in our daily practice. Although there are clear guidelines for severe AS management, cardiologists often have few treatment options for patients with moderate AS; however, there is higher mortality in this patient subgroup versus an age-matched population. The authors revi...
Background: Primary aldosteronism is the leading cause of secondary hypertension, the management of this disease requiring an interdisciplinary approach.
Objectives: Evaluation of evolutionary features of patients with secondary hypertension and primary aldosteronism.
Methodology: We have followed 26 patients diagnosed with secondary hypertension...
Survey and long-term clinical post-trial follow-up (interviews/correspondence) on nine chronic, post spinal cord injury (SCI) tetraplegics.
To assess feasibility of the use of Electroencephalography-based Brain-Computer Interface (EEG-BCI) for reaching/grasping assistance in tetraplegics, through a robotic arm.
Physical and (neuromuscular) Rehabili...
Addressing emergency cardiac pathology is an area studied very little by students of the fourth year of study at the University of Medicine during the cardiology module. The aim of this study is to optimize the relationship between theoretical knowledge they obtain from the cardiology course and their application in the emergency room for urgent re...
Heart failure (HF) is a common, costly, disabling and deadly syndrome. Heart failure is a progressive disease characterized by high prevalence in society, significantly reducing physical and mental health, frequent hospitalization and high mortality (50% of the patients survive up to 4 years after the diagnosis, the annual mortality varying from 5%...
Thyroid pathology is rarely involved in the pathogenesis of sudden death in young people, and usually, when this is the case, is associated with acute changes of thyroid hormone blood levels. Three main thyroid causes of sudden death are known and used in tanathologic chains: thyrotoxicosis, myxedematous coma and, as of recently, lymphocytic thyroi...
In this paper, we search an adequate quantitative method based on minimum variance spectral analysis in order to reflect the dependence of the speech quality on the correct positioning of the dental prostheses. We also search some quantitative parameters, which reflect the correct position of dental prostheses in a sensitive manner.
During the past decade idiopathic venous thromboembolism has become a separate entity, a chronic illness which has required prolonged anticoagulation and other prevention strategies to avoid recurrences. This article reviews recent developments regarding unprovoked venous thromboembolism and its relation with thrombophilia. In the beginning, the la...
The paper emphasizes the importance of verbal and nonverbal communication in the development of student license thesis on medical topics. We present the methods that can be used in the learning process of students in medical education. Thus, from theoretical and practical presentations made to them, responses to different questions need to be taken...
Heart failure (HF) is a syndrome characterized by high prevalence in society, frequent hospitalization, reduced quality of life and high mortality (overall, 50% of patients are dead at an interval of 4 years, annual mortality varying from 5% to 75%). Outcomes in heart failure are highly variable, prognosis of individual patients differs considerabl...
A 43-year-old white male, obese (BMI = 43.2), heavy smoker (60 cigarettes/day), arrives at the hospital in a stable non-ST-segment elevation myocardial infarction (NSTEMI) setting [chest pain which started 4 h prior to his arrival, electrocardiogram (ECG) showing negative T-waves in inferior leads and flattened T-waves in lateral leads, troponin el...
The aim of this article is to analyze the effects of the molecular basis of vascular events following spinal cord injury and their contribution in pathogenesis.
First of all, we reviewed the anatomy of spinal cord vessels.
The pathophysiology of spinal cord injuries revealed two types of pathogenic mechanisms. The primary event, the mechanic traum...
The aim of this article is to analyze the vascular dysfunctions occurring after spinal cord injury (SCI). Vascular dysfunctions are common complications of SCI. Cardiovascular disturbances are the leading causes of morbidity and mortality in both acute and chronic stages of SCI.Neuroanatomy and physiology of autonomic nervous system, sympathetic an...
The diabetic patients represent a population with a high risk of morbidity and mortality because of vascular complications. Out of them, all the patients with acute ST-elevation myocardial infarction have a more reserved prognostic than those without diabetes mellitus. Moreover, the patients with impaired glucose tolerance have a more severe evolut...
This paper mainly represents the synthesis of the theoretical basis for an interdisciplinary health/engineering project of scientifically advanced] applied research. The project aims a non-invasive data gathering, at the skin level, for important physiological signals - by means of somel specific sensors embedded in special textile fabrics, approac...
The image of the future European textile and clothing industry can only be built around a dynamic concept, based on multidisciplinary knowledge and innovation, flexible integrated and client oriented, through business networks. The functionalization of textile materials is of major importance and represents and essential component in the textile pr...
Left ventricular (LV) remodeling after acute ST-elevation myocardial infarction (STEMI) is an important predictor of mid and long-term prognosis. Pathological cardiac remodeling is associated with the development of LV systolic dysfunction and of congestive heart failure. The role of angiotensin converting enzyme (ACE) inhibitors in preventing card...
Cardio-vascular diseases are the major cause of mortality, the first role had ischemic cardiac disease follow-up by stroke. Each of these diseases account for some 15 million deaths per year that is 30% from the total number of death. The highest mortality is registered in the countries of former USSR and those of east Europe. France and Japan had...
In this paper, the most adequate quantitative parameters are sought that reflect the dependence of speech sound distortions on the correct position of dental mountings. We suggest the Hurst fractal exponent and some parameters calculated from the Paul wavelet transform of speech sound are useful as quantitative parameters. The investigations are fo...
The end-point of this retrospective study was to evaluate the standard of care in terms of in-hospital morbidity and mortality for patients with acute myocardial infarction (AMI) treated by thrombolysis within the first 12 hours from the start of the symptoms in five cardiology centers from Bucarest for a period of 5 years (2000-2004). This retrosp...
The end-point of this retrospective study was to evaluate the standard of care in terms of in-hospital morbidity and mortality for patients with acute myocardial infarction (AMI) treated by thrombolysis within the first 12 hours from the start of the symptoms in five cardiology centers from Bucarest for a period of 5 years (2000-2004). This retrosp...
In 1999 Romania started its health care reform by promulgating the Health Insurance Law. A functional and efficient health care system needs procedures for monitoring and evaluation of the medical services, communication between different service providers and entities involved in the system, integration and availability of the information. The fin...
Non-insulin-dependent diabetes mellitus (NIDDM) is frequently associated with macroangiopathies and coronary heart diseases. Lipoprotein lipase (LPL), an enzyme known to undergo significant functional alterations in diabetic state, is also a potential atherogenic protein. Since, to the best of our knowledge, there are no data concerning LPL secrete...
