Courteney TunsteadNational University of Ireland, Maynooth | NUI Maynooth · Department of Biology
Courteney Tunstead
Bachelor of Science
PhD student investigating MSC therapy in the treatment of ARDS | BSc Biomedical Science | Founder of Courteney’s Corner
About
8
Publications
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Publications
Publications (8)
Enhancing mesenchymal stromal cell (MSC) therapeutic efficacy through licensing with proinflammatory cytokines is now well established. We have previously shown that macrophage migration inhibitory factor (MIF)‐licensed MSCs exerted significantly enhanced therapeutic efficacy in reducing inflammation in house dust mite (HDM)‐driven allergic asthma....
Macrophage migration inhibitory factor (MIF) expression is controlled by a functional promoter polymorphism, where the number of tetranucleotide repeats (CATTn) corresponds to the level of MIF expression. To examine the role of this polymorphism in a pre‐clinical model of allergic asthma, novel humanized MIF mice with increasing CATT repeats (CATT5...
Mesenchymal Stromal Cells (MSCs) have attracted attention as a cell-based therapy due to their
immunomodulatory and immunoregulatory properties. MSCs have been investigated in clinical trials for the
treatment of a variety of inflammatory conditions, such as Acute Respiratory Distress Syndrome (ARDS).
Studies have shown that MSCs require activation...
