Cosmin Iulian Codrea

• Doctor of Engineering
• The Institute of Physical Chemistry of the Romanian Academy

New gelatin methacryloyl (GelMA)—strontium-doped nanosize hydroxyapatite (SrHA) composite hydrogel scaffolds were developed using UV photo-crosslinking and 3D printing for bone tissue regeneration, with the controlled delivery capacity of strontium (Sr). While Sr is an effective anti-osteoporotic agent with both anti-resorptive and anabolic propert...

A challenge in tissue engineering and the pharmaceutical sector is the development of controlled local release of drugs that raise issues when systemic administration is applied. Strontium is an example of an effective anti-osteoporotic agent, used in treating osteoporosis due to both anti-resorptive and anabolic mechanisms of action. Designing bon...

Development of efficient controlled local release of drugs that prevent systemic side effects is a challenge for anti-osteoporotic treatments. Research for new bone-regeneration materials is of high importance. Strontium (Sr) is known as an anti-resorptive and anabolic agent useful in treating osteoporosis. In this study, we compared two different...

Juglone (5-hydroxy-1,4-naphthoquinone) (J) is a naphthoquinone structured allelochemical that is mostly found in the roots, leaves, nut-hulls, bark, and wood of walnut (Juglans regia). In this study, the biocompatibility, mechanical, thermal, chemical, morphological, and antimicrobial properties of the poly(lactic acid) (PLA) (w/v)/J (10, 20, 30 mg...

In the COVID-19 pandemic context, numerous concerns have been raised regarding the hygienic status of certain objects we interact with on a daily basis, and especially cash money and their potential to harbor and transmit pathogenic bacteria. Therefore, in the present study, we analyzed different currency bills represented by British pounds (5£, 10...

Acid rain is a major problem for animals, plants, buildings, and also for the top glass of photovoltaic (PV) solar panels and greenhouses. Air pollutants such as NOx, NH3, and H2S can mix with water in the atmosphere to form acid rain. It was discovered that atmospheric water vapor adsorbed on the surface of glass can also lead to corrosion of the...

This research aims to synthesize hydroxyapatite powders from a biogenic calcium source (hen eggshell) and study the effect of two maturation methods (a classical method and a combined short time maturation at 135°C in microwave-assisted hydrothermal conditions) on its final properties. The synthesized specimens consist of nanometric polycrystalline...

Multifunctional composite coatings composed of metal oxide nanoparticles dispersed in polymer matrices are an advanced solution to solve the problem of stone heritage deterioration. Their innovative design is meant to be stable, durable, transparent, easy to apply and remove, non-toxic, hydrophobic, and permeable. Coating formulations for the prote...

The increase in osteoporotic fracture worldwide is urging bone tissue engineering research to find new, improved solutions both for the biomaterials used in designing bone scaffolds and the anti-osteoporotic agents capable of promoting bone regeneration. This review aims to report on the latest advances in biomaterials by discussing the types of bi...