Cosmin Boteanu

• Hospital Central de la Cruz Roja San José y Santa Adela

Background Beta‐lactams (BLs) are the predominant cause of immediate allergic reactions to drugs. Immediate hypersensitivity reactions (IHR) with positive provocation tests and negative skin and in vitro tests have undetermined mechanisms. We evaluated whether biomarkers of IgG‐dependent neutrophil activation could help to assess this subgroup of B...

Opinion statement To summarize the current knowledge of diagnosis in immediate perioperative hypersensitivity reactions (PHR). There is a growing interest in the diagnosis and management of PHR. Recently several clinical guidelines published on PHR; however, its implementation is unknown. The diagnosis and management of PHR is a challenge for both...

Background Cefazolin is a common trigger of perioperative anaphylaxis. The diagnostic approach is controversial as the optimal concentration for skin testing is uncertain, drug provocation tests (DPTs) are contraindicated in severe reactions, and in vitro tests are not thoroughly validated. Objective We aimed to characterize a large number of pati...

Cual es el momento mas recomendable para administrar la profilaxis antibiotica quirurgica y de esta manera y si se produce una reaccion favorexer un mas sencillo estudio alergologico de la misma

Purpose of Review To summarize the current knowledge of diagnosis and management of patients with perioperative immediate hypersensitivity reactions (POH) Recent Findings The diagnosis and management of POH is a challenge for both allergologists and anesthesiologists. They are rare entities; its difficulty lies in its poor clinical specificity, at...

Over recent years, the consumption of quinolones as first-line treatment has increased, leading to a growth in incidence of hypersensitivity reactions (HSRs) to this group of antibiotics. Both diagnosis and management of HSRs to quinolones are complex and controversial. These practical guidelines aim to provide recommendations for an effective clin...

Table of contents Poster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101) P92 16 years of experience with proton pump inhibitors (PPIs) Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna Martinez P93 Allergy evaluation of quinol...

IntroductionThe number of patients with Implantable Venous-Access Port Systems (IVAPS) seen in Phlebotomy Outpatients, as well as requests for drawing blood samples through this system instead of conventional venepuncture, are continuously increasing.The aim of this study was to assess if drawing blood samples through IVAPS, despite using a specifi...

IntroductionThe identification and immediate notification of critical results is crucial to assure appropriate patient care. The Emergency Laboratory has led a POCT blood gases and electrolytes project for 10 years (17 decentralized analyzers), according to scientific societies recommendations (SEQC and NACB). The objective of this study is to revi...