Cornelius Fendler

Cornelius Fendler
University of Hamburg | UHH · Institute of Applied Physics

Dr. rer. nat.

About

10
Publications
1,110
Reads
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77
Citations
Citations since 2016
10 Research Items
77 Citations
201620172018201920202021202205101520253035
201620172018201920202021202205101520253035
201620172018201920202021202205101520253035
201620172018201920202021202205101520253035

Publications

Publications (10)
Article
Brain-on-a-chip (BoC) concepts should consider three-dimensional (3D) scaffolds to mimic the 3D nature of the human brain not accessible by conventional planar cell culturing. Furthermore, the essential key to adequately address drug development for human pathophysiological diseases of the nervous system, such as Parkinson's or Alzheimer's, is to e...
Article
Full-text available
Directed guidance of neurites is a pre-requisite for tailor-made designs of interfaces between cells and semiconducting components. Grayscale lithography, reactive ion etching, and ultraviolet nanoimprint lithography are potent semiconductor industry-compatible techniques for a cost- and time-effective fabrication of modulated surfaces. In this wor...
Article
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices. So far, human pluripotent stem cell-derived neurons—a revolutionary tool for studying physiological function and modeling neurodegenerative diseases—have not been applied to such innovative substrates, due to the highly demanding nat...
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In article number 1800329, Robert H. Blick and co‐workers utilize the inherently given freedom of the 3D design feasible by two‐photon polymerization direct laser writing for the tailor‐made preparation of neuronal cell culture platforms. Specifically, the scaffold consists of microtowers connected to each other by free‐standing tubes. Neurite outg...
Article
Full-text available
Correction for ‘Culturing and patch clamping of Jurkat T cells and neurons on Al 2 O 3 coated nanowire arrays of altered morphology’ by Jann Harberts et al. , RSC Adv. , 2019, 9 , 11194–11201.
Article
While modern day integrated electronic circuits are essentially designed in a 2D fashion, the brain can be regarded as a 3D circuit. The thus enhanced connectivity enables much more complex signal processing as compared to conventional 2D circuits. Recent technological advances in the development of nano/microscale 3D structuring have led to the de...
Article
Full-text available
Nanowire substrates play an increasingly important role for cell cultures as an approach for hybrid bio-semiconductor junctions. We investigate Jurkat T cells and neurons from mice cultured on Al 2 O 3 coated ordered and randomly distributed nanowires. Cell viability was examined by life/membrane staining reporting comparable viability on planar an...
Article
Full-text available
We make use of the physical mechanism of proton pumping in the so-called Complex I within mitochondria membranes. Our model is based on sequential charge transfer assisted by conformational changes which facilitate the indirect electron-proton coupling. The equations of motion for the proton operators are derived and solved numerically in combinati...

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