
Constantinos H KarabatsasUniversity of West Attica Athens Greece
Constantinos H Karabatsas
MD, PhD, FEBOphth, MRCOphth, FRCSEd(Ophth)
About
65
Publications
10,154
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1,359
Citations
Introduction
Additional affiliations
April 2018 - present
University of West Attica (UNIWA)
Position
- Professor (Assistant)
Description
- • Teaching to undergraduate students • Postgraduate Teaching (MSc course) to Medical Doctors (Ophthalmologists) and Registered Optometrists
April 2018 - present
University of West Attica (UNIWA)
Position
- Professor (Assistant)
September 2014 - present
Hellenic Eye Bank Demokritos
Position
- Board Member
Education
October 2000 - October 2000
University of Crete – Medical School, VEIC
Field of study
- Refractive Surgery, Ophthalmology
September 1997 - September 1997
May 1996 - May 1996
European Board of Ophthalmology
Field of study
- Ophthalmology
Publications
Publications (65)
This prospective observational study investigates the impact of cataract surgery on anterior segment
parameters in nonglaucomatous and primary open-angle glaucoma (POAG) eyes, utilizing anterior segment
optical coherence tomography (AS-OCT). The study involved 42 Caucasian patients, divided into a control
group and a POAG group. Comprehensive ophth...
Purpose: To compare the morphological changes in the meibomian glands and meibomian glands loss between contact lens and non-contact lenses wears in a young population. The contact lens wearers wore C.L. for max 6 years. Methods: Examination of the meibomian gland (MG) by using a corneal topographer CSO MODI 2 incorporating Phoenix-Meibography Imag...
Placido topographer CSO Phoenix had been used to measure 30 peoples corneas with astigmatism < 0.50 Dc (University of West Attica) and their refractive maps were taken. The refractive power map was used with measurements taken at the horizontal (180°), vertical (90°), and oblique axes (45° and 135°) for each of these 30 people. The keratometric mea...
To compare the effect of bimatoprost and the fixed combination latanoprost-timolol (LTFC) on 24-hour systolic (SBP) and diastolic (DBP) blood pressure and on 24-hour ocular perfusion pressure (OPP).
200 patients with glaucoma or ocular hypertension, controlled on the unfixed combination of latanoprost and timolol or eligible for dual therapy being...
Purpose
To compare 1-year results: safety, efficacy, refractive and keratometric stability, of femtosecond myopic laser-assisted in situ keratomileusis (LASIK) with and without concurrent prophylactic high-fluence cross-linking (CXL) (LASIK-CXL).
Methods
We studied a total of 155 consecutive eyes planned for LASIK myopic correction. Group A repres...
Background
The purpose of this study was to investigate plasma homocysteine levels and polymorphisms in genes encoding enzymes in the metabolic pathway of homocysteine in association with primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXFG).
Methods
A total of 156 glaucoma patients (76 with POAG and 80 with PXFG) and 135 contro...
The aim of this work was to demonstrate the ultrastructural appearance of the human ocular surface glycocalyx in normal subjects. Conjunctival tissue specimens from 7 normal subjects were obtained by bulbar conjunctival biopsy, and examined by transmission electron microscopy. The free surface of the apical conjunctival epithelial cells was charact...
h4>ABSTRACT
A 57-year-old woman was treated by photodynamic therapy for macular edema due to idiopathic juxtafoveal telangiectasis (presumed type 1A) without subretinal neovascularization. Initial visual acuity of the treated eye was 20/200 and it improved to 20/40 by 3 months after the photodynamic therapy session. Visual acuity remained stable 3...
To compare the effect of bimatoprost and the fixed combination of latanoprost and timolol (LTFC) on 24-hour mean intraocular pressure (IOP) after patients are switched from a nonfixed combination of latanoprost and timolol.
Randomized, double-masked, multicenter clinical trial.
Two hundred patients with glaucoma or ocular hypertension.
Included wer...
Understanding the mathematical relationships of volume blood flow and wall shear stress with respect to microvessel diameter is necessary for the study of vascular design. Here, for the first time, volume flow and wall shear stress were quantified from axial red blood cell velocity measurements in 104 conjunctival microvessels of 17 normal human vo...
Purpose: To study whether absolute change in intraocular pressure (IOP) when
switching between treatments is correlated with central corneal thickness (CCT).
Methods: This was a multicentric randomized, double masked clinical trial in 7
Europen centers. A total of 200 glaucoma or ocular hypertension patients participated.
Included were patients who...
Purpose: : To study the intraoperative and postoperative efficacy of the use of capsular tension rings (CTR) in cataract surgery complicated by Zinn zonule instability.
Methods: : Retrospective chart review of 47 eyes from 46 patients who underwent cataract surgery from May 2001 to November 2005 in the Ophthalmology Department, University of Thess...
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare entity first described in 1975, affecting mainly young women and adolescents. We present a case of a 52-year-old female patient (one of the oldest in the literature) who complained of fever, anorexia, nausea, and vomiting. After she was admitted to our hospital, laboratory tests rev...
To demonstrate the ultrastructural appearance of the conjunctival surface epithelium in patients with Sjögren's syndrome (SS) compared with normal subjects.
Conjunctival tissue specimens from seven normal subjects and eight patients with SS were obtained by bulbar conjunctival biopsy and examined by transmission electron microscopy.
The average num...
The aim of the present study was to evaluate the effect of latanoprost monotherapy on the aqueous humour concentrations of TGF-beta1, MMP-2, TIMP-2, MMP-9 and gelatinolytic activity in patients treated for exfoliative glaucoma (XFG). Aqueous samples from 50 XFG patients treated with latanoprost and 50 age-matched XFG patients treated with timolol w...
To study the influence of glycemic control and the presence of microalbuminuria on the initial response to panretinal photocoagulation (PRP) in patients with a high-risk proliferative diabetic retinopathy (PDR).
This was a prospective cohort study with a two-by-two factorial design. We used full-scattered PRP to treat 115 eyes of type 2 diabetic pa...
Purpose: To present our initial experience with the Ex–Press (Optonol) miniature glaucoma implant for intraocular pressure (IOP) control.
Methods: Twenty (20) eyes of 20 patients ( 11 males, 9 females ) with medically uncontrolled primary open angle glaucoma ( 11 eyes ) or exfoliative glaucoma ( 9 eyes ) were treated surgically with the use of an...
To evaluate the 24-hour efficacy of brimonidine purite versus dorzolamide, each added to latanoprost.
Double-masked, 2-center, prospective, crossover comparison.
Primary open-angle glaucoma (POAG) subjects.
Subjects were randomized to brimonidine purite or dorzolamide, each given twice daily, for the first 6-week treatment period after a 6-week lat...
The association between retinopathy in type 2 diabetes [diabetic retinopathy (DR)] and the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene has been investigated in several case-control studies. These studies rendered contradictory results, some indicating that the polymorphism is associated with the risk of developing DR...
To evaluate agreement in measurements of astigmatic axis power and location between keratometry and computer assisted videokeratography (corneal topography) on normal corneas with less than 1.50 D of idiopathic astigmatism.
Keratometric readings with the 10 SL/O Zeiss ophthalmometer and corneal topographic maps with the TMS-1 were obtained by two i...
To compare the diurnal intraocular pressure (IOP) efficacy and safety of timolol vs latanoprost in subjects with exfoliation glaucoma (XFG).
A 3-month prospective, single-masked, active-controlled, parallel comparison performed in six centres in Greece that randomized subjects in a 1 : 1 ratio to either latanoprost in the evening (2000 hours) and p...
PURPOSES To evaluate the efficacy and safety dorzolamide 2 versus brimonidine 0.15 each given twice daily added to latanoprost 0.005 given each evening.
METHODS 33 patients were initiated on latanoprost therapy for up to six weeks and randomized to either dorzolamide or brimonidine for six weeks in a double-masked fashion (Period 1). Patients were...
Purpose: To compare intraocular pressure (IOP) measurements with the Goldman applanation tonometer and the digital portable tonometer TGDc-01 (Raysan Enterprise, Russia) which measures IOP through the eyelids.
Methods: IOP measurements were taken in a total of 100 eyes ( 40 normals, 40 eyes with glaucoma, 20 eyes with corneal disease) by two indep...
Objective
To compare postoperative astigmatism induced by two different suturing techniques in penetrating keratoplasty (PKP).
To create a clinically useful classification for post-keratoplasty corneas based on corneal topography.
A total of 360 topographic maps obtained with the TMS-1, from 95 eyes that had undergone penetrating keratoplasty (PKP), were reviewed independently by two examiners in a masked fashion, and were categorised according to a proposed classification...
To compare postoperative astigmatism induced by two different suturing techniques in penetrating keratoplasty (PKP).
A monocenter, prospective, randomized clinical trial with a longitudinal 1-year follow-up.
A total of 95 eyes undergoing PKP were randomized into 2 groups. Of these, 51 eyes were allocated to the combined interrupted and continuous s...
To assess the effectiveness of computerized videokeratography (CVK) in refining the surgical design and in improving predictability of surgical correction of postkeratoplasty astigmatism.
A prospective, controlled, randomized, clinical trial.
A total of 31 postkeratoplasty eyes, divided into 2 groups (group A, 16 eyes; group B, 15 eyes), with more...
To evaluate intra- and interobserver variability in measurements on normal and astigmatic corneas with keratometry and computerized videokeratography.
Keratometric readings with the 10 SL/O Zeiss keratometer and topographic maps with the TMS-1 were obtained by two independent examiners on 32 normal and 33 postkeratoplasty corneas. Inter- and intrao...
This study was initiated to investigate the role of different therapeutic modalities in the outcome of the surgical treatment of pterygium.
The results of treatment of pterygia with a variety of surgical techniques were studied in 56 eyes (49 patients) operated on at Bristol Eye Hospital during a period of five years. The surgical techniques includ...
As new methods for corneal curvature measurement have evolved, users of videokeratscopes need to know the practical limitations of these instruments. We assessed agreement between keratometry and videokeratography in measuring highly astigmatic corneas.
Two independent examiners made three keratometric and videokeratographic measurements on each of...
Carbomer gel is a water-soluble polymeric resin that has been reported to maintain the tear film in contact with the eye for an extended period. The efficacy and safety of this new artificial tear were assessed.
A multicenter, single-masked, randomized, placebo-controlled study was carried out on 123 patients with moderate-to-severe dry eyes. The p...
A 12-year-old high myope girl presented with a cilioretinal artery occlusion in her left eye. Three years previously, she had undergone posterior scleral support surgery to prevent the progression of her myopia. The general medical workup of the patient did not reveal any causative factor for retinal artery occlusion. A possible relation between th...
Astigmatism is a common complication after penetrating keratoplasty (PKP) that
affects visual rehabilitation in a considerable number of patients. The scope of this
thesis was to investigate different aspects of problem "post-PKP astigmatism" with
the aid of computer assisted video-keratography (CAVK) through four parallel
studies.
First, the agree...
A 78-year-old female patient who had a third penetrating keratoplasty for aphakic bullous keratopathy and iris fixation of a posterior chamber intraocular lens using a single, 10-0 nylon running suture technique developed a suture track leak postoperatively. Attempts to ease the tension on the suture track reduced the astigmatism and stopped the le...
In spite of improvements in surgical techniques, donor materials and postoperative care, high astigmatism remains a quite common problem following penetrating keratoplasty [1]. Whenever the residual astigmatism cannot be corrected with spectacles or contact lenses, surgical treatment is required. Relaxing incisions combined with compression sutures...
Purpose: To assess the agreement in astigmatic measurements between standard keratometry and computer assisted videokeratography (CAVK), in postkeratoplasty corneas. Methods: Keratometry readings (Zeiss keratometer) and corneal topographic maps (TMS-1, Tomey) were obtained by two examiners on 28 postkeratoplasty corneas, within a year from the PKP....
Pellucid marginal corneal degeneration (PMCD) is an uncommon cause of inferior peripheral corneal ectasia, affecting patients between the ages of 20 and 40 years. Although histopathologically it is considered a variant of keratoconus, it differs in that the marked corneal steepening occurs more inferiorly, above a narrow band of corneal stromal thi...
This study was initiated to investigate risk factors for and outcome of Acanthamoeba keratitis.
Results of treatment were studied in 22 patients (23 eyes) presenting to Bristol Eye Hospital between 1985 and February 1995. Details related to the use and disinfection of contact lenses were also obtained. An additional two patients who were seen at Br...