Conchita Martín

Complutense University of Madrid | UCM · Facultad de Odontología

Uneven gingival margins may cause visible asymmetries during smiling and may reflect alterations in the tooth shape and morphology, particularly in cases requiring restorative procedures. Despite being perceived as a minor health condition, presence of uneven gingival margins usually impacts the smile aesthetics and could affect the individual's ap...

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determine the effectiveness and safety of botulinum toxins as an intervention to reduce the negative consequences of sleep bruxism in adults.

The prevalence of intrabony defects in patients with advanced periodontitis stages III and IV is high. These patients usually need both periodontal treatment and orthodontic therapy, including tooth movement through bone defects, to improve masticatory function, aesthetics, and overall quality of life. Clinical practice guidelines recommend periodo...

Objectives: To assess the risk of bias (RoB) of randomized controlled trials (RCTs) published in dental journals in the Spanish language. Methods: A systematic retrospective survey was conducted of all RCTs published from 1980 to 2019 in dentistry Spanish and Latin American journals. We extracted data and performed RoB assessments using the Cochra...

In stage IV periodontitis patients with pathologic tooth migration (PTM), interdisciplinary treatment includes regenerative periodontal surgery (RPS) with an application of biomaterials and orthodontic therapy (OT) to restore function, esthetics and thereby quality of life (QoL). In a 24-month randomized trial we explored the synergy between regene...

Background: Without a phase of retention after successful orthodontic treatment, teeth tend to 'relapse', that is, to return to their initial position. Retention is achieved by fitting fixed or removable retainers to provide stability to the teeth while avoiding damage to teeth and gums. Removable retainers can be worn full- or part-time. Retainer...

Aim: To obtain input from multiple stakeholders and generate agreement on essential outcomes in implant dentistry using the Delphi methodology and incorporate them into an international consensus defining a core outcome set. Materials and methods: Candidate outcomes in implant dentistry were generated from scientific evidence through five commis...

Aim: To obtain input from multiple stakeholders and generate agreement on essential outcomes in implant dentistry using the Delphi methodology and incorporate them into an international consensus defining a core outcome set. Materials and methods: Candidate outcomes in implant dentistry were generated from scientific evidence through five commis...

Application of intermittent forces by vibration is proposed as an easy‐to‐use accelerator of dental movement. The purpose of this study was to determine the effect of intermittent vibrational force application during orthodontic aligner treatment on receptor activator of nuclear factor‐kappa B ligand (RANKL) and osteoprotegerin (OPG) concentrations...

Background: We conducted research to investigate the effects of the eruption sequence of posterior teeth, arch dimensions, and incisor inclination on dental crowding. Material and methods: A cross-sectional analytic study was performed on 100 patients (54 boys and 46 girls; mean ages: 11.69 and 11.16 years, respectively). Seq1 (canine-3-/second...

Objectives The aims of the present longitudinal retrospective observational case series study were to investigate the survival and success rates of primary non-surgical endodontic therapy. Materials and methods Patients with at least one endodontically treated tooth (ETT), with 5 years of follow-up and in compliance with the recall programme of at...

Aim: To answer the following PICOS question: in adult patients with peri-implantitis, what is the efficacy of surgical therapy with chemical surface decontamination of implant surfaces in comparison with surgical therapy alone or surgery with placebo decontamination, on probing pocket depth (PD) reduction and bleeding on probing (BoP)/suppuration...

Cone beam computed tomography (CBTCT) scans (n = 45) and digital dental casts (n = 45) were both used to measure the maxillary transverse dimensions in patients with impacted maxillary canines. The objectives were to explore the associations of these dimensions with the impaction and patient characteristics, and to compare the measurements between...

Background Class III malocclusion is associated with high sexual dimorphism, especially in individuals older than 13 years of age, with significant differences in growth between males and females during the pubertal and postpubertal stages, and in adulthood. The aim of this research was to examine differences between males and females in long-term...

Background: The objective of this study was to determine the effect of antibiotic prophylaxis in preventing postoperative infections after extraction of impacted mandibular third molars. Material and methods: A Parallel-group, randomized, blind, placebo-controlled trial was performed. 154 patients were randomly allocated to 2 groups; experimenta...

Aim To compare the outcomes after early (4 weeks post-surgically) or late (6 months post-surgically) orthodontic therapy (OT) following regenerative surgery of intrabony defects (IDs). Material and Methods In a multi-center, parallel-group, randomized clinical trial 43 patients with stage IV periodontitis were randomized to receive either early (n...

Aim To answer these PICO questions: #1: In adult patients with malocclusion, what are the effects of orthodontic tooth movement (OTM) on clinical attachment level (CAL) changes in treated periodontitis patients with a healthy but reduced periodontium compared to non‐periodontitis patients? #2: In adult patients with treated periodontitis and malocc...

Bonding strategies within different brackets and dental materials are still a challenge concerning adhesion and dental surface damage. This study compared the shear and tensile bond strength of orthodontic ceramic and metallic brackets to enamel, acrylic, and ceramic surfaces after thermal cycling. Dental surfaces were divided into three groups: en...

The main aim of this study was to generate an adequate sub-phenotypic clustering model of class III skeletal malocclusion in an adult population of southern European origin. The study design was conducted in two phases, a preliminary cross-sectional study and a subsequent discriminatory evaluation by main component and cluster analysis to identify...

Current phenotypic characterizations of Class III malocclusion are influenced more by gender or ethnic origin than by raw linear skeletal measurements. The aim of the present research is to develop a Class III skeletal malocclusion sub-phenotype characterization based on proportional cranial measurements using principal component analysis and clust...

Aim: To answer the following PICOS questions: in patients with periodontitis, which is the efficacy of adjunctive systemic antimicrobials, in comparison with subgingival debridement plus a placebo, in terms of probing pocket depth (PPD) reduction, in randomized clinical trials with at least 6 months of follow-up. Material and methods: A systemat...

Aim: To answer the following PICOS question: in adult patients with periodontitis, which is the efficacy of adjunctive locally delivered antimicrobials, in comparison with subgingival debridement alone or plus a placebo, in terms of probing pocket depth (PPD) reduction, in randomized clinical trials with at least 6 months of follow-up. Material a...

Aim: To assess the efficacy and adverse effects of resective surgery compared to access flap in patients with periodontitis. Methods: Randomized controlled trials with a follow-up ≥ 6 months were identified in ten databases. Screening, data extraction, and quality assessment were conducted by two reviewers. The primary outcome was probing pocket...

Aim: To evaluate the efficacy of adjunctive therapies in reducing gingivitis and plaque by means of a systematic review of randomized clinical trials (RCTs). Material and methods: A search protocol was designed to identify 6-month RCTs that investigated efficacy of adjuncts to mechanical plaque control on gingivitis and plaque. Following screeni...

Background Poor oral hygiene is strongly associated with oral and systemic diseases. Alongside mechanical tooth cleaning, the adjunctive use of mouthrinses has been widely advocated. Although research on the efficacy of various mouthrinse formulations is very active, there are a lack of conclusive data regarding their adverse effects. Methods We u...

Objective: The aim of this study was to explore the methods, reporting and transparency of clinical trials in orthodontics and compare them to the field of periodontics, as a standard within dentistry. Design/setting: Cross-sectional bibliographic study. Methods: A total of 300 trials published in 2017-2018 and evenly distributed in orthodonti...

Aim The aim of this network meta‐analysis (NMA) was to compare the efficacy of different oral hygiene products for chemical biofilm control, in 6‐month home‐use, randomised clinical trials (RCTs), in terms of changes in gingival index (GI). Material and Methods Six‐month RCTs assessing GI were identified and screened for inclusion. Relevant inform...

Objectives The primary aim of this systematic review was to evaluate the effect of external tooth bleaching products on plaque indices and to compare it to a placebo or a negative control. Methods A protocol was developed aimed to answer the next focused question: What is the effect of tooth bleaching compared to no‐treatment or a placebo, in subj...

Objective: We aimed to systematically review articles investigating the efficiency of the clustering of skeletal class III malocclusion phenotypic subtypes of different ethnic origins as a diagnostic tool. Methods: The review protocol was structured in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses stateme...

Background To identify controlled clinical trials (CCTs) published in Spanish and in Latin American dental journals, and provide access to this body of evidence in a single source. Methods Handsearching, following Cochrane Collaboration guidelines, of CCTs published in Spanish dental journals from Spain and Latin America. For each eligible trial,...

Objective: To assess the clinical, microbiological, and patient-based effects of using a cetylpyridinium chloride (CPC) toothpaste and mouth rinse in orthodontic patients. Design: Parallel randomized controlled, triple-blinded trial (participants, examiners, outcomes' assessors). A computer-generated list was used to allocate treatments. Central...

Objectives: The aim of this study was to systematically review the available literature about in vitro orthodontic bond strength tests regarding bonding brackets to acrylic teeth. Methods: A comprehensive electronic database search with no date or language limits was conducted. Relevant studies were selected based on predefined criteria: in vitro i...

Background: A necessary step to use neuromuscular analysis as diagnostic tool is to establish normal reference values for the physiological range in a healthy population. Surface electromyographic (sEMG) activity of the jaw muscles and mandibular kinematics were measured in young adults with theoretically ideal dental occlusion to determine normal...

Objective: This systematic review aimed to evaluate the scientific evidence on the efficacy of desensitizing mouthwashes for the treatment of dentin hypersensitivity (DH) and root sensitivity (RS). Material and methods: A thorough search in MEDLINE, PubMed and Cochrane Plus Library was conducted up to February 2015. Randomized clinical trials, p...

Introducción Cada vez es más frecuente que pacientes adultos demanden someterse a tratamiento ortodóntico para mejorar su función y su estética dental. Así mismo, las consecuencias de la enfermedad periodontal (con mayor incidencia con la edad), como la migración dental patológica, requieren de ortodoncia para su corrección. Existe controversia sob...

Aim: The aim of this systematic review and network meta-analysis (NMA) was to compare the efficacy of different anti-plaque chemical agents, in 6-month, home-use, randomised clinical trials (RCTs), in terms of plaque index (PlI) changes. Material and methods: RCTs assessing PlI were identified, screened and evaluated for inclusion. Relevant info...

Objectives: The aim of this study was to investigate whether the presence of a natural mediotrusive contact influences electromyographic (EMG) pattern activity in patients with temporomandibular disorders (TMDs). Method: Bilateral surface EMG activity of the anterior temporalis (AT), masseter (MM), and sternocleidomastoid (SCM) muscles was recor...

Objectives: There is scarce knowledge regarding the influence of a natural mediotrusive contact on mandibular and cervical muscular activity. The purpose of this study was to analyze the EMG activity of the anterior temporalis (AT) and sternocleidomastoid (SCM) muscles during awake grinding in healthy subjects with or without a natural mediotrusive...

Objective: To compare the effect of placing the definitive abutment at the time of implant placement versus at a later stage, on the soft and hard tissue changes around dental implants. Material and methods: Platform-switched implants were placed in the posterior maxilla or mandible of partial edentulous patients and they were randomized to rece...

To assess the soft tissue and to determine the potential association between changes in soft and hard tissue after early chin cup treatment in prognathic children. A total of 42 children (21 boys, 21 girls) with skeletal Class III malocclusion due to mandibular prognathism were examined before (mean age, 8.5 ± 0.5 years) and after (mean age, 11.4 ±...

Objective. This study evaluated the effect of a natural mediotrusive contact on the electromyographic (EMG) activity of the anterior temporalis and sternocleidomastoid muscles during chewing in healthy subjects. Materials and methods. The study sample included two groups of 15 subjects each (Group 1: with natural mediotrusive contact; Group 2: with...

The reliability of spectrophotometric measurements of gingival color has not been tested. The purpose of this study was to evaluate the repeatability and reproducibility of gingival color measurements with a digital spectrophotometer. Measurement error was estimated by determining the interrater agreement and by repeating measurements in different...

Summary OBJECTIVE: The aim of this prospective longitudinal investigation was to compare the relationship between the temporomandibular joint (TMJ) condyles and the temporal fossae by means of tomography before and after the orthodontic correction of Class II, division 1 malocclusion using the activator appliance. The final sample consisted of 26 c...

AimThe aim of this systematic review was to evaluate the efficacy of adjunctive chemical plaque control for managing gingivitis, in 6-month, home-use, randomised clinical trials (RCT).Material and MethodsA protocol was designed, including inclusion and exclusion criteria to identify RCT assessing gingival and/or bleeding indexes. Electronic and han...

Objective Systematically review the scientific evidence for efficiency of anti-inflammatory agents against gingivitis, either as solo treatments or adjunctive therapies.MethodsA protocol was developed aimed to answer the following focused question: “Are anti-inflammatory agents effective in treating gingivitis as solo or adjunct therapies?”. RCTs a...

Objective: To determine whether the morphology of the mandible (size and shape) differs among adult subjects with skeletal Class I, Class II and Class III. Methods: A sample of 187 white adults (92 males, 95 females; age range, 20–30 years; mean age, 25.6 ± 4.2 years) from Granada (southern Spain) were randomly selected and grouped according to t...

Objective: The aim of this randomized study was to compare the effect of slow maxillary expansion with expansion plates and Hyrax expanders on the lateral shift of the mandible after cross-bite correction. Method: Thirty children (15 boys, 15 girls), aged 7.1 to 11.8 y., with unilateral posterior cross-bite and functional shift were randomly divi...

Aim: The aim of this study was to test the agreement between orthopantomography (OPG) based 2D measurements and the KPG index, a new index based on 3D Cone Beam Computed Tomography (CBCT) images, in predicting orthodontic treatment duration and difficulty level of impacted maxillary canines. Materials and methods: OPG and CBCT images of 105 impa...

Objective: The aim of this study was to identify controlled clinical trials (CCT) published in dentistry journals from Spain, as well as to assess their methodological quality, with an emphasis on their design and reporting of results Method: A retrospective electronic and hand search of the available literature was conducted, starting in 2011, of...

Objective: the aim of this study was to test two buffer solutions in order to attain a reliable and reproducible analysis of inflammatory cytokines (IL-1β, IL-6, TNF-α, OPG, OPN and OC), in gingival crevicular fluid (GCF) by flow cytometry. Material and Methods: GCF samples from healthy volunteers were collected with perio-paper strips and diluted...

The aim of this randomised prospective study was to evaluate the effects of slow maxillary expansion with expansion plates and Hyrax expanders on the kinematics of the mandible after cross-bite correction. Thirty children (15 boys and 15 girls), aged 7·1–11·8, with unilateral cross-bite and functional shift were divided into two groups: expansion p...

The aim of this study was to evaluate both intra- and interoperator reliability of a radiological three-dimensional classification system (KPG index) for the assessment of degree of difficulty for orthodontic treatment of maxillary canine impactions. Cone beam computed tomography (CBCT) scans of fifty impacted canines, obtained using three differen...

Objectives This study was designed to determine the effects of probiotics in prevention and/or treatment of periodontal diseases. Materials and methods We performed broad searches in the MEDLINE, Embase, and Cochrane databases and selected articles that satisfied the description of randomized clinical trials comparing the administration of probioti...

To obtain an overall quantitative estimate of the association between pregnancy and gingival inflammation. Medline and EMBASE databases were searched through August 2011. Prospective cohort or cross-sectional studies assessing the effect of pregnancy on gingival inflammation evaluated by the gingival index (GI) and/or bleeding on probing were inclu...

Objectives: The aim of this double blind randomized clinical trial was to evaluate the clinical efficacy of a topical sialogogue spray containing 1% malic acid on elderly people affected by xerostomia Methods: Forty one individuals (mean age: 78.7 years) with xerostomia were randomly assigned to two groups. The first group (“intervention group”)...

We have recently presented the Old Spanish Pointer dog, with a 15-20% spontaneous congenital cleft palate rate, as a unique experimental model of this disease. This study aimed to describe the cleft palate of these dogs for surgical research purposes and to determine whether congenital cleft palate influences maxillofacial growth. Seven newborn Old...

Objectives: A longitudinal study was performed to evaluate the jaw muscle activity and mandibular kinematics after Teuscher activator treatment and at 2 years after orthodontic treatment completion. Material and Methods: Twenty-seven children with Class II division 1 malocclusion were evaluated before treatment (T0; mean: 11.6 years), after functi...

Abstract OBJECTIVE: To evaluate the expression of an activator of nuclear factor-kappa (RANK), osteoprotegerin (OPG), osteopontin (OPN), and transforming growth factor ß1 (TGF-ß1) in gingival crevicular fluid (GCF) of teeth subjected to orthodontic forces. MATERIALS AND METHODS: A randomized, pilot clinical trial including 10 healthy volunteers was...

Background and objective: Studies performed over the last 15 years have suggested that periodontal diseases may be associated with adverse pregnancy outcomes. However, this association has not been found in all populations. The aim of this study was to evaluate whether periodontal status and the presence of specific periodontal pathogens may influ...

Objectives: The aim of this study was to select a model of cephalometric variables to predict best results of early chin-cup treatment of Class III malocclusion due to mandibular prognatism. Methods: Forty-two patients (20 boys, 22 girls) with Class III malocclusion were treated with a chin-cup for a period of 2.31±1.04 years. Cephalometric radio...

Objectives: To examine the activity of jaw muscles at rest and during maximal voluntary clenching (MVC) in children with unilateral posterior crossbite (UPXB) and functional lateral shift in the early mixed dentition and to evaluate sex differences. Material and Methods: The sample included 30 children (15 males, 15 females) aged 6 to 10 years old,...

Objective: The aim of this prospective case series study was to evaluate the influence of early orthodontic tooth movement on the level of Nitric Oxide (NO) in saliva. Method: Ten healthy females (mean age 25.8 yr) requiring orthodontic treatment participated in the study. Ten age-matched non-treated females served as control group. Exclusion cri...

Objectives: To assess calcitonin (CT) levels in gingival crevicular fluid (GCF) during initial orthodontic tooth movement in both tension and compression sites, and its possible association with the experienced dental pain.. Methods: Fifteen children (mean age: 12.6 years) requiring orthodontic closure of the upper midline diastema participated i...

Objective: To evaluate the expression of an activator of nuclear factor-kappa (RANK), osteoprotegerin (OPG), osteopontin (OPN), and transforming growth factor ß1 (TGF-ß1) in gingival crevicular fluid (GCF) of teeth subjected to orthodontic forces. Materials and methods: A randomized, pilot clinical trial including 10 healthy volunteers was condu...

There are many cone beam computed tomography (CBCT) scanners available on the market: detector technology, algorithm precision, and scanner settings influence image quality. The aim of this study was to compare the accuracy of linear measurements made on images of the same sample obtained using two different CBCT scanners. Twenty-eight linear measu...

The aim of this systematic review was to evaluate the best timing for placing implants after tooth extraction, by comparing early vs. delayed implant placement and evaluating the hard and/or soft tissue ridge dimensional changes and the outcomes related with implant survival and prosthesis success. An online search of the main databases including T...

This systematic review aims to evaluate the scientific evidence on the efficacy in the surgical protocols designed for preserving the alveolar ridge after tooth extraction and to evaluate how these techniques affect the placement of dental implants and the final implant supported restoration. A thorough search in MEDLINE-PubMed, Embase and the Coch...

The aim of this study was to evaluate masticatory muscle activity and kinematics of mandible changes in children with unilateral posterior cross-bite (UPXB) after orthodontic treatment, and one year after retention. Twenty-five children with UPXB and functional mandibular shift were evaluated before treatment (mean age 12.5years), after treatment (...

The aim of this controlled randomized clinical trial was to evaluate the efficacy of a xenogeneic collagen matrix (CM) to augment the keratinized tissue around implants supporting prosthetic restorations at 6 months when compared with the standard treatment, the connective tissue autograft, CTG). This randomized longitudinal parallel controlled cli...

Objectives: The aim of this prospective study was to compare the changes in mandibular shift and rest position in males and females with functional unilateral posterior cross-bite (FUCB) after maxillary expansion. Methods: The sample included 15 males and 15 females that were balanced regarding age, dental and skeletal maturation. Skeletal asymme...

Objectives: The aim of this transversal study was to compare the differences in electromyographic (EMG) activity of masticatory muscles at rest and during clenching between males and females with functional unilateral posterior cross-bite (FUCB). Methods: The sample included 15 males and 15 females with FUCB (6-9 years of age) in the early mixed de...

To evaluate clinically and radiographically immediate implants 5 years after insertion and to compare them with delayed-placed implants in the same subjects Twenty-two consecutive patients that needed at least two implants for replacing hopeless teeth, one immediately upon extraction and the other in a delayed fashion (at least 4 months post-extrac...

Objectives: to test for differences in dental maturation between control (C) and functional unilateral posterior cross-bite (FPCB) children and between sides within each group (right vs. left in C and cross-bite vs. non-cross-bite in FPCB subjects); to compare the dental age using the Demirjian method between groups and between sides within each gr...