Clement Achille

SGS · Health

3D-printed porous microfluidics has been proposed to realize complex passive lab-on-chips. The performance of these devices depends on capillary flow design and control. To this end, a predictive multiscale model of capillary imbibition in porous channels obtained through powder-based 3D printing was developed. Pore-network modelling was used to ob...

Rapid diagnostic testing at the site of the patient is essential when a fully equipped laboratory is not accessible. To maximize the impact of this approach, low‐cost, disposable tests that require minimal user‐interference and external equipment are desired. Fluid transport by capillary wicking removes the need for bulky ancillary equipment to act...

Rapid diagnostic testing at the site of the patient is essential when a fully equipped laboratory is not accessible. In article number 2008712, Rob Ameloot and co-workers present a novel powder-based 3D-printing method that enables monolithic capillarity-driven microfluidic devices. Precise spatial control over the internal surface chemistry of por...

Correction for ‘4D synchrotron microtomography and pore-network modelling for direct in situ capillary flow visualization in 3D printed microfluidic channels’ by Agnese Piovesan et al. , Lab Chip , 2020, 20 , 2403–2411, DOI: 10.1039/D0LC00227E.

Powder-based 3D printing was employed to produce porous, capillarity-based devices suitable for passive microfluidics. Capillary imbibition in such devices was visualized in-situ through dynamic synchrotron X-ray microtomography performed at the European Synchrotron Radiation Facility (ESRF) with sub-second time resolution. The obtained reconstruct...

High fluxes and low fouling are practically highly desired in all membrane processes. One generic way to realize this is by introducing surface patterns on the membrane to increase the active area and the surface roughness. A new method to prepare flat-sheet patterned membranes using a patterned knife combined with a modified phase inversion proces...

Stand-alone and portable lab-on-chips (LOC) can be obtained by exploiting capillary flow in porous media. Poly-methyl methacrylate (PMMA) platforms obtained through powder-based 3D printing are appropriate for capillarity-driven LOCs. However, fluid flow in such platforms needs to be characterized well. For this purpose a 3D pore-network (PN) was e...

The present invention relates to a method for three dimensional printing of a porous object enabling the capillary transport of hydrophilic fluids, for use as liquid handling device, for example as a point of care diagnostic device. The invention also provides the porous object obtainable or obtained by such methods, and its use in liquid handling...

Computer-aided fabrication technologies combined with simulation and data processing approaches are changing our way of manufacturing and designing functional objects. Also in the field of catalytic technology and chemical engineering the impact of additive manufacturing, also referred to as 3D printing, is steadily increasing thanks to a rapidly d...

RNA interference (RNAi) is a promising approach for cancer treatment. Site specific and controlled delivery of RNAi could be beneficial to the patient, while at the same time reducing undesirable off-target side effects. We utilized electrospinning to generate a biodegradable scaffold capable of incorporating and delivering a bioactive plasmid enco...