Claus-Martin Muth

Claus-Martin Muth
Ulm University | UULM · Department of Anesthesiology, Division of Emergency medicine

MD, PhD

About

132
Publications
24,632
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2,555
Citations
Citations since 2016
6 Research Items
1261 Citations
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200

Publications

Publications (132)
Article
Full-text available
Introduction: Cardiac arrest is a leading cause of death in industrialised countries. Cardiopulmonary resuscitation (CPR) guidelines follow the principles of closed chest compression as described for the first time in 1960. Mechanical CPR devices are designed to improve chest compression quality, thus considering the improvement of resuscitation ou...
Article
Full-text available
Background Cardiac arrest is an event with a limited prognosis which has not substantially changed since the first description of cardiopulmonary resuscitation (CPR) in 1960. A promising new treatment approach may be mechanical CPR devices (mechanical CPR). Methods In a retrospective analysis of the German Resuscitation Registry between 2007–2014,...
Article
Full-text available
The aim of the EuReCa ONE study was to determine the incidence, process, and outcome for out of hospital cardiac arrest (OHCA) throughout Europe. This was an international, prospective, multi-centre one-month study. Patients who suffered an OHCA during October 2014 who were attended and/or treated by an Emergency Medical Service (EMS) were eligibl...
Article
Der Tauchunfall (DecompressionIncident, DCI) entsteht in der Dekompressionsphase von Tauchgängen. Ursächlich hierfür kann entweder eine arterielle Gasembolie (AGE) infolge eines pulmonalen Barotraumas sein oder aber die Bildung von Inertgasblasen infolge der Reduktion des Umgebungsdrucks beim Auftauchen. Während traditionell die Annahme galt, dass...
Article
Emergency medical service is called by a 54-year-old man bitten by his rattlesnake. Upon initial survey we find the patient in a cardiopulmonary stable condition. He has bite marks and pain on his rapidly swelling middle finger of his right hand. Our initial treatment is immobilization of the patient. The snake raiser has already called the poison...
Article
Cardiac arrest is associated with a poor outcome if cardiopulmonary resuscitation (CPR) is delayed. Nevertheless, CPR performance by laypersons in witnessed cardiac arrest is frequently poor. The present study evaluated the effect of a media campaign on CPR performance. CPR performance of 1000 individuals who did not have any medical background was...
Article
Decompression illness (DCI) is the most important emergency resulting from exposure to hyperbaric environments. Immediate diagnosis and management mostly allow for complete recovery without sequelae. Emergency and critical care physicians need to be aware of the possible symptoms, since there are no DCI-specific symptoms, and the clinical presentat...
Conference Paper
Anästh Intensivmed 56:S424 WV-4.6 | In der Geschichte der Kardiopulmonalen Reanimation (CPR) wurde manch innovativer Ansatz in die internationalen Leitlinien aufgenommen, während andere verheißungsvolle Ideen später wieder verworfen werden mussten. Eine vielversprechende Entwicklung sind Kardiokompressionssysteme, über die in jüngster Zeit eine z...
Article
In-water resuscitation (IWR) is recommended in the 2010 guidelines of the European Resuscitation Council. As IWR represents a physical challenge to the rescuer, a novel Rescue Tube device with an integrated "Oxylator" resuscitator might facilitate IWR. The aim of the present study was the assessment of IWR using the novel Rescue Tube device. Tidal...
Article
Hintergrund Die Prognose von Patienten nach Herzstillstand hängt wesentlich vom schnellstmöglichen Beginn einer suffizienten Wiederbelebung ab. Das Ziel von Erste-Hilfe-Kursen ist es, die grundlegenden Maßnahmen zur Lebensrettung zu vermitteln um die Zeit bis zum Eintreffen des Rettungsdienstes zu überbrücken. Die vorliegende Studie untersucht die...
Article
Full-text available
Background Drowning is a relevant worldwide cause of severe disability and death. The delay of ventilations and chest compressions is a crucial problem in drowning victims. Hence, a novel helicopter-based ALS rescue concept with in-water ventilation and chest compressions was evaluated. Methods Cardio pulmonary resuscitation (CPR) and vascular acce...
Article
Introduction: Full-face-masks (FFM) prevent the diver's face from cold and can support nasal breathing underwater. The aim of the study was to evaluate the effect of the use of FFMs on lung function and wellbeing. Methods: Twenty-one, healthy, non-asthmatic divers performed two cold-water dives (4⁰C, 25 min, 10 metres' depth) - one with a FFM an...
Article
Ein 25-jähriger Mann wird gegen 19.00 Uhr abends leblos im Wasser treibend von Angestellten eines Schwimmbades entdeckt, während die Schwimmmeister im kleineren Nachbarbecken Schwimmunterricht für Kinder geben. Die Angestellten ziehen den Mann aus dem Wasser und beginnen mit Wiederbelebungsmaßnahmen.
Conference Paper
Anästh Intensivmed 55:S13-S14 | Fragestellung Ein halbes Jahrhundert nach Erstbeschreibung der Kardiopulmonalen Reanimation (CPR) durch Kouwenhoven et al. im Jahr 1960 hat sich trotz intensiver Forschung und ständiger Weiterentwicklungen kaum etwas an der schlechten Prognose der Patienten verändert [1]. Eine besondere Bedeutung für das Überleben...
Article
Background: Diving with self-contained underwater breathing apparatus (SCUBA) has become a popular recreational activity in children and adolescents. Compared to adults, children are expected to be at increased risk for hypothermia during SCUBA diving, which may also result in bradycardia. Research question: The objective of this study was to evalu...
Article
Decompression injuries are potentially life-threatening incidents, generated by a rapid decline in ambient pressure in scuba diving, which results in formation of gas bubbles in the blood and tissues. Regardless whether decompression sickness (DCS) or arterial gas embolism (AGE) is present, the most important therapy in the field is oxygen resuscit...
Article
Objective: Drowning is associated with a high mortality and morbidity and a common cause of death. In-water resuscitation (IWR) in the case of drowning accidents has been recommended by certain resuscitation guidelines in the last several years. IWR has been discussed controversially in the past, especially with regard to the delay of chest compre...
Article
Full-text available
In-water resuscitation has recently been proposed in the European resuscitation guidelines. Initiation of mechanical ventilation underwater might be considered when an immediate ascent to the surface is impossible or dangerous. The present study evaluated the feasibility of such ventilation underwater. A resuscitation manikin was ventilated using a...
Article
Decompression injuries are potentially life-threatening incidents, generated by a rapid decline in ambient pressure in scuba diving, which results in formation of gas bubbles in the blood and tissues. Regardless whether decompression sickness (DCS) or arterial gas embolism (AGE) is present, the most important therapy in the field is oxygen resuscit...
Article
Introduction: Drowning is a common cause of death in young adults. The 2010 guidelines of the European Resuscitation Council call for in-water-resuscitation (IWR). There has been controversy about IWR amongst emergency and diving physicians for decades. The aim of the present study was assessing the efficacy of IWR. Methods: In this randomized c...
Chapter
Ein 62-jähriger Wattwanderer wird von der Mannschaft eines Seenotkreuzers aufgenommen und im Hafen an den Notarzt übergeben. Er sei aus unklarer Ursache kurzzeitig bewusstlos gewesen und mit dem Kopf unter Wasser gelangt. Die körperliche Untersuchung ergibt bis auf eine Lippenzyanose und auskultatorisch Rasselgeräusche über der Lunge keine weiteren...
Article
Full-text available
Background: Acute pulmonary embolism (APE) is an important clinical problem in patients after major surgery and often remains a difficult diagnosis because of unspecific clinical symptoms. Therefore, we investigated the role of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the detection of APE. Methods: In 44 patients with s...
Article
Introduction: In water resuscitation has been reported to enhance the outcome of drowning victims. Mouth-to-mouth ventilation during swimming is challenging. Therefore, the efficacy of ventilation utilities was evaluated. Methods: Ventilation was assessed with the Oxylator ventilator, as well as the consecutive self-contained underwater breathin...
Article
Recompression during decompression has been suggested to possibly reduce the risk of decompression sickness (DCS). The main objective of the current study was to investigate the effects of FLIRT (First Line Intermittent Recompression Technique) on bubble detection in man. 29 divers underwent 2 simulated dives in a dry recompression chamber to a dep...
Article
Full-text available
Decompression injuries are potentially life-threatening incidents, generated by a rapid decline in ambient pressure. Although typically seen in divers, they may be observed in compressed air workers and others exposed to hyperbaric environments. Decompression illness (DCI) results from liberation of gas bubbles in the blood and tissues. DCI may be...
Article
Unlabelled: Diving with self-contained underwater breathing apparatus (SCUBA) has become a popular recreational activity in children and adolescents. This article provides an extensive review of the current literature. Conclusions: Medical contraindications to SCUBA diving for adults apply to children and adolescents, too, but must be adapted. A...
Article
The purpose of this study was to monitor heart rate (HR) and rhythm during open water SCUBA dives. Nine children performed 25-min open water SCUBA dives to 8 m depth. Before, during and after these dives, ECG was recorded. Compared with predive heart rate, heart rate declined by -24 ± 8% (range -36%; -15%) during the dive. In some children a furthe...
Article
In response to the letter of colleagues Hawkins and Sempsrott, we totally agree that in future articles on drowning, only the new terminology should be used. We are aware of the World Congress on Drowning 2002 in Amsterdam, and recognize that a change in the terminology of drowning accidents was proposed. In the following years there was a debate o...
Article
Introduction: Scuba diving has become a popular recreational activity among children and adolescents. However, compared to data in adults, only scarce information is available with regard to both possible and actual complications of scuba diving. Methods: Any complications that could be observed in 44 boys and girls aged 8 to 15 years while partici...
Article
An increasing number of children and adolescents is diving with Self-Contained Underwater Breathing Apparatus (SCUBA). SCUBA diving is associated with health risks such as pulmonary barotrauma, especially in children and in individuals with airflow limitation. As no data has been published on the effects of open-water diving on pulmonary function i...
Article
Inzwischen ist Tauchen eine sehr beliebte und verbreitete Sportart und wird zunehmend auch von Frauen in fast allen Altersstufen ausgeübt. Es ist deshalb wahrscheinlich, im gynäkologischen Alltag mit tauchmedizinischen Fragestellungen konfrontiert zu werden. Um nun gynäkologischen Kollegen eine adäquate Beratung ihrer tauchenden Patientinnen zu erm...
Article
Hyperbaric oxygen (HBO) therapy is increasingly being used in different areas of medical practice. While demonstrated to be effective in several settings, its mechanism of action is not well understood. In the present study, we determined the effects of HBO on wound epithelialization and neovascularization in an in vivo hairless mouse ear “impaired...
Article
Full-text available
Peripartum cardiomyopathy (PPCM) is an uncommon type of heart failure of unknown cause occurring late in pregnancy or in the postpartum period. Because of its low incidence and the unspecific symptoms PPCM is often undetected or misdiagnosed. Unfortunately, PPCM is a disease whose underlying etiology and natural history remain incompletely understo...
Article
Full-text available
Hyperbaric oxygen (HBO) therapy is used for the treatment of a variety of diseases, but also leads to oxidative stress as a result of increased formation of reactive oxygen species. The consequences may be damage to the lung, the central nervous system and the genome. The oxidative attack on DNA causes, among other damage, single and double strand...
Article
Full-text available
A single exposure to hyperbaric oxygen (HBO), i.e., pure oxygen breathing at supra-atmospheric pressures, causes oxidative DNA damage in humans in vivo as well as in isolated lymphocytes of human volunteers. These DNA lesions, however, are rapidly repaired, and an adaptive protection is triggered against further oxidative stress caused by HBO expos...
Article
Full-text available
The incidence and nature of cardiac arrhythmias during static apnea were studied by monitoring the electrocardiogram (ECG) and oxygen saturation (SaO(2)) of 16 recreational breath-hold divers. All subjects completed a maximal apnea with a mean (+/-SD) breath-hold duration of 281 (+/-73) s without clinical complications. Both heart rate (HR) and SaO...
Article
Unfälle am und im Wasser sind im Vergleich zu anderen Notsituationen selten. Daher spielen diese in der Ausbildung zum Rettungsassistenten und Notarzt nur eine untergeordnete Rolle. Allerdings erfordern Unfälle am und im Wasser vom Rettungsdienst häufig spezielle Rettungsmaßnahmen und eine besondere medizinische Versorgung. Die vorliegende Arbeit s...
Article
Full-text available
Breath-hold divers employ glossopharyngeal insufflation (GI) in order to prevent the lungs from compressing at great depth and to increase intrapulmonary oxygen stores, thus increasing breath-hold time. The presented case study shows the physiological data and dynamic magnetic resonance imaging (dMRI) findings of acute hyperinflation, deliberately...
Article
Full-text available
About 10% of all sport scuba divers are children and adolescents. Little is known about the particular risks and consequences of this sport on a child's health. Due to the peculiarities of childhood anatomy and physiology, certain restrictions apply to the diving fitness of children and adolescents. Before starting scuba training, the presence of p...
Article
Etwa 10% aller Sporttaucher sind jünger als 18Jahre. Bislang gibt es nur unzureichende Erkenntnisse zu möglichen Risiken und insbesondere Folgen des Tauchens mit Gerät im Kindesalter. Aufgrund der Besonderheiten der kindlichen Anatomie und Physiologie müssen für Kinder und Jugendliche Einschränkungen der medizinischen Fitness zum Tauchen und auch d...
Article
Hypothermia in near-drowning victims is a serious problem that impacts clinical decision-making. The purpose of this trial was to determine the reliability of tympanic temperature measurements compared to oral temperature measurements after immersion in water. After ethical approval was obtained, we studied oral and tympanic temperature in 25 volun...
Article
Full-text available
Competitive breath-hold divers (BHD) employ glossopharyngeal insufflation (GI) to increase intrapulmonary oxygen stores and prevent the lungs from dangerous compressions at great depths. Glossopharyngeal insufflation is associated with inflation of the lungs beyond total lung capacity (TLC). It is currently unknown whether GI transiently over-diste...
Article
Diving with self-contained underwater breathing apparatuses has become a popular sports activity and an increasing number of persons participate in this kind of sport. Until now only little is known about the diving behaviour and the medical problems of scuba divers. Aim of the study was to collect epidemiological data of diving behaviour and of il...
Chapter
Introduction: Hyperbaric oxygen has been shown both in experimental and clinical settings to improve wound healing, particularly in cases where the tissue is compromised. In the present study, we measured the effects of hyperbaric oxygen therapy (HBO) on wound epithelialization and neovascularization in an in vivo hairless mouse ear »impaired« woun...
Chapter
Der schwere Tauchunfall ist ein potenziell lebensbedrohliches Ereignis, das bei Tauchern und anderweitig überdruckexponierten Personen in der Dekompressionsphase auftreten kann. Durch einen raschen Abfall des Umgebungsdruckes kommt es zur Bildung freier Gasblasen in Blut und Geweben und dadurch zur Dekompressionserkrankung (DCI, von engl. »decompre...
Article
Full-text available
In diving mammals splenic contraction increases circulating red cell volume, whereas in humans increased haemoglobin concentrations have been reported. It is unknown, however, whether repetitive apnea diving also comprises an adaptive increase in total red cell volume as reported in endurance athletes. The first aim of the study therefore was to in...
Article
Full-text available
Emergencies on or in water are relatively rare in the rescue service. For this reason, water accident treatment and management does not receive much attention in the training of emergency medicine physicians. Consequently doctors working in emergency medicine often have minimal knowledge in this area. On the other hand, the number of fatal accident...
Article
Notfälle am und im Wasser sind im Rettungsdienst vergleichsweise selten. Entsprechend spielen die Wasserunfälle in der Notarztausbildung eine eher untergeordnete Rolle. Notwendiges einsatzspezifisches Wissen und Erfahrung sind bei den im Notarztdienst tätigen Kollegen daher meist gering ausgeprägt. Andererseits nimmt die Zahl der tödlichen Unfälle...
Article
We previously reported in healthy volunteers that a cantaloupe melon extract chemically combined with wheat gliadin (melon extract/gliadin) and containing SOD, catalase and residual glutathione peroxidase (GPx), protected against DNA strand-break damage induced by hyperbaric oxygen (HBO), a well-established model of DNA damage resulting from oxidat...
Article
Diving accidents represent a departure from the routine practice of emergency physicians. The incidence of non-fatal diving accidents is reported as 1-2 per 10,000 dives. Apart from adequate intravenous hydration, oxygen is the only medication with a proven effect in the treatment of diving accidents. After a typical diving accident, administration...
Article
Für den Notarzt stellt der Tauchunfall trotz einer Inzidenz für nichttödliche Tauchunfälle von 1–2/10.000 Tauchgänge eine Situation abseits der Routine dar. Neben adäquater Flüssigkeitssubstitution ist Sauerstoff das einzige Medikament, für das eine spezifische Wirkung bei der Behandlung eines Tauchunfalls belegt ist. Nach einem typischen Tauchunfa...
Article
Obstructive changes in lung function have been reported with cumulative scuba diving exposure. The aim of this study was to investigate the decline in FEV1 in scuba divers over time. Prospective controlled cohort study. German Naval Medical Institute. Four hundred sixty-eight healthy, male, military scuba divers and 122 submariners (control subject...
Article
To investigate the hemodynamic and metabolic effects of the peroxisome proliferator-activated receptor (PPAR)-gamma ligand and nuclear-factor (NF)-kappa B inhibitor 15-deoxy-Delta12,14-prostaglandin-J2 (15d-PGJ2) during long-term, hyperdynamic porcine endotoxemia. Prospective, randomized, controlled experimental study with repeated measures. Invest...
Chapter
Full-text available
The modalities of HBO therapy application must be seen according to the patient’s clinical situation. The range is from patients with minor impairment of state of health to critically ill patients. The potentially hazardous hyperbaric environment must be taken in to account in the selection of patients to be treated with HBO. With carefully perform...
Article
It is increasingly recognized that professional diving may elicit adverse long-term effects on the lungs, but conflicting results have been reported from distinct diving cohorts. This study reports the longitudinal change in lung function in professional divers who employ closed-circuit oxygen rebreathing apparatuses. All oxygen divers who attended...
Article
Full-text available
This study aimed to establish epidemiological data on diving habits and outcome of subjects with respiratory diseases who are considered at increased risk for diving injuries. We conducted a cross-sectional demographics and prevalence study by distribution of an anonymous questionnaire with an issue of a widespread sport diving magazine. The questi...
Article
Apnea diving is a fascinating example of applied physiology. The record for apnea diving as an extreme sport is 171 meters, 8:58 minutes. The short time beneath the surface induces profound cardiovascular and respiratory effects. Variations of blood-gas tensions result from the interaction of metabolism and the rapid sequence of compression and dec...